| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Oyan, F Nilsen, A Goksøyr, B Holmqvis. Partial cloning of constitutive and inducible nitric oxide synthases and detailed neuronal expression of NOS mRNA in the cerebellum and optic tectum of adult Atlantic salmon (Salmo salar). Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891583. |
expression studies by means of in situ hybridization revealed abundant nnos mrna transcripts in distinct neuronal populations throughout the purkinje cell layer of the corpus cerebellum and the periventricular layer of the optic tectum. |
2000-09-25 |
2023-08-12 |
Not clear |
| O J Castejon, P Sim. Three-dimensional morphology of cerebellar climbing fibers. A study by means of confocal laser scanning microscopy and scanning electron microscopy. Scanning. vol 22. issue 4. 2000-09-14. PMID:10958387. |
the intracortical pathway of cerebellar climbing fibers have been traced by means of scanning electron microscopy (sem) and confocal laser scanning microscopy (clsm) to study the degree of lateral collateralization of these fibers in the granular purkinje cell and molecular layers. |
2000-09-14 |
2023-08-12 |
Not clear |
| A M Haeberlé, C Ribaut-Barassin, G Bombarde, J Mariani, G Hunsmann, J Grassi, Y Baill. Synaptic prion protein immuno-reactivity in the rodent cerebellum. Microscopy research and technique. vol 50. issue 1. 2000-08-22. PMID:10871550. |
although the physiological functions of prp(c) remain unknown, the concentration of prp(c) almost exclusively at the purkinje cell synapses in the cerebellum suggests its critical involvement in the synaptic relationships between cerebellar neurons in agreement with their known vulnerability to prp deficiencies. |
2000-08-22 |
2023-08-12 |
Not clear |
| J Udagawa, T Hatta, H Naora, H Otan. Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice. Brain research. vol 868. issue 2. 2000-08-18. PMID:10854577. |
at e16.5, it was expressed in the premamillary hypothalamic nucleus, superficial gray matter of the superior colliculus, external germinal and purkinje cell layers of the cerebellum, and facial nucleus. |
2000-08-18 |
2023-08-12 |
mouse |
| F J Seil, R Drake-Bauman. TrkB receptor ligands promote activity-dependent inhibitory synaptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884321. |
addition of neurotrophins to untreated cerebellar cultures did not increase the complement of purkinje cell axosomatic synapses. |
2000-08-03 |
2023-08-12 |
mouse |
| F J Seil, R Drake-Bauman. TrkB receptor ligands promote activity-dependent inhibitory synaptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884321. |
application of antibodies to bdnf and nt-4 to cerebellar explants exposed to picrotoxin to increase neuronal activity prevented the hyperinnervation of purkinje cell somata by inhibitory terminals characteristic of cultures exposed to picrotoxin alone. |
2000-08-03 |
2023-08-12 |
mouse |
| K Mertz, T Koscheck, K Schillin. Brain-derived neurotrophic factor modulates dendritic morphology of cerebellar basket and stellate cells: an in vitro study. Neuroscience. vol 97. issue 2. 2000-07-27. PMID:10799762. |
the dendrites of cerebellar basket/stellate cells show a highly stereotyped orientation relative to granule cell axons (parallel fibers) and purkinje cell dendrites. |
2000-07-27 |
2023-08-12 |
Not clear |
| N Hadj-Sahraoui, F Frédéric, N Delhaye-Bouchaud, J Marian. Gender effect on Purkinje cell loss in the cerebellum of the heterozygous reeler mouse. Journal of neurogenetics. vol 11. issue 1-2. 2000-07-21. PMID:10876649. |
gender effect on purkinje cell loss in the cerebellum of the heterozygous reeler mouse. |
2000-07-21 |
2023-08-12 |
mouse |
| J L Ingram, S M Peckham, B Tisdale, P M Rodie. Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. Neurotoxicology and teratology. vol 22. issue 3. 2000-07-12. PMID:10840175. |
reductions in purkinje cell number and cerebellar volume, particularly of the posterior lobe, have also been reported in people with autism. |
2000-07-12 |
2023-08-12 |
human |
| S J Baloyannis, V Costa, G Deretzi, D Michmizo. Intraventricular administration of substance p increases the dendritic arborisation and the synaptic surfaces of Purkinje cells in rat's cerebellum. The International journal of neuroscience. vol 101. issue 1-4. 2000-07-07. PMID:10765993. |
the increased number of synapses between the purkinje cell dendrites and the parallel fibres in the animals, which received substance p intraventricularly, in correlation to control animals, supports a neurotrophine-like activity of the substance p in the mammalian cerebellum, enforcing the pre-programmed capability of the purkinje cells to develop new synaptic surfaces. |
2000-07-07 |
2023-08-12 |
rat |
| N Inamura, T Araki, Y Enokido, C Nishio, S Aizawa, H Hatanak. Role of p53 in DNA strand break-induced apoptosis in organotypic slice culture from the mouse cerebellum. Journal of neuroscience research. vol 60. issue 4. 2000-06-23. PMID:10797547. |
exposure to bleomycin significantly increased the numbers of tunel-, p53-, and c-jun-positive neurons in the wild-type mouse cerebellar internal granular layer (igl) and purkinje cell layer (pl). |
2000-06-23 |
2023-08-12 |
mouse |
| C Hansel, D J Linde. Long-term depression of the cerebellar climbing fiber--Purkinje neuron synapse. Neuron. vol 26. issue 2. 2000-06-23. PMID:10839365. |
long-term depression of the cerebellar climbing fiber--purkinje neuron synapse. |
2000-06-23 |
2023-08-12 |
Not clear |
| M Hobom, S Dai, E Marais, L Lacinova, F Hofmann, N Klugbaue. Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit. The European journal of neuroscience. vol 12. issue 4. 2000-06-21. PMID:10762351. |
in situ hybridization of mouse brain sections revealed the highest expression of alpha2delta-2 mrna in the purkinje cell layer of the cerebellum, habenulae and septal nuclei, and a lower expression in the cerebral cortex, olfactory bulb, thalamic and hypothalamic nuclei, as well as the inferior and superior colliculus. |
2000-06-21 |
2023-08-12 |
mouse |
| U Wüllner, M Weller, J Kornhuber, A Bornemann, J B Schulz, P Riederer, T Klockgethe. Altered expression of calcium- and apoptosis-regulating proteins in multiple system atrophy Purkinje cells. Movement disorders : official journal of the Movement Disorder Society. vol 15. issue 2. 2000-06-09. PMID:10752575. |
additional dna end-labeling (isel) studies revealed only one possible apoptotic purkinje cell nucleus, but nuclei in the cerebellar white matter, probably oligodendrocytes, in the cerebellum of patients with msa. |
2000-06-09 |
2023-08-12 |
Not clear |
| J Kotera, K Fujishige, K Omor. Immunohistochemical localization of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in rat tissues. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 48. issue 5. 2000-06-09. PMID:10769052. |
immunohistochemical analysis showed that the anti-pde5 antibody detected immunoactive materials in purkinje cell layers of the cerebellum, proximal renal tubules, collecting renal ducts, and epithelial cells of pancreatic ducts in rats. |
2000-06-09 |
2023-08-12 |
human |
| B Lingärde, S A Jönsson, A Luts, A Bru. Cerebellar abnormalities in mental illness. A study on Purkinje cell density in schizophrenic men. European child & adolescent psychiatry. vol 9. issue 1. 2000-06-08. PMID:10795852. |
the linear purkinje cell density in the cerebellar vermis was investigated in a small cohort of adult onset schizophrenic men with well-documented hippocampal abnormalities. |
2000-06-08 |
2023-08-12 |
Not clear |
| K Tsutsui, K Ukena, M Usui, H Sakamoto, M Takas. Novel brain function: biosynthesis and actions of neurosteroids in neurons. Neuroscience research. vol 36. issue 4. 2000-06-07. PMID:10771104. |
we recently demonstrated neuronal neurosteroidogenesis in the brain and indicated that the purkinje cell, a typical cerebellar neuron, actively synthesizes several neurosteroids de novo from cholesterol in both mammals and non-mammals. |
2000-06-07 |
2023-08-12 |
Not clear |
| K Tsutsui, K Ukena, M Usui, H Sakamoto, M Takas. Novel brain function: biosynthesis and actions of neurosteroids in neurons. Neuroscience research. vol 36. issue 4. 2000-06-07. PMID:10771104. |
pregnenolone sulfate, one of neurosteroids synthesized in the purkinje neuron, may contribute to some important events in the cerebellum by modulating neurotransmission. |
2000-06-07 |
2023-08-12 |
Not clear |
| T Yokota, T Uchihara, J Kumagai, T Shiojiri, J J Pang, M Arita, H Arai, M Hayashi, M Kiyosawa, R Okeda, H Mizusaw. Postmortem study of ataxia with retinitis pigmentosa by mutation of the alpha-tocopherol transfer protein gene. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 4. 2000-06-05. PMID:10727494. |
because robust expression of alpha-ttp was detected in the cerebellum as well as in the liver and the tissue concentration of vitamin e in the cerebellum was still low even after oral supplementation, the mild purkinje cell loss might be related to the mutant alpha-ttp in the cerebellum. |
2000-06-05 |
2023-08-12 |
Not clear |
| D H Gutmann, Y Zhang, M J Hasbani, M P Goldberg, T L Plank, E Petri Hensk. Expression of the tuberous sclerosis complex gene products, hamartin and tuberin, in central nervous system tissues. Acta neuropathologica. vol 99. issue 3. 2000-05-23. PMID:10663963. |
in the mouse cerebellum in vivo, tuberin predominantly localizes to the perinuclear region of the purkinje cell, whereas hamartin is distributed along neuronal or astrocytic processes. |
2000-05-23 |
2023-08-12 |
mouse |