| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Canepar. Is Purkinje Neuron Hyperpolarisation Important for Cerebellar Synaptic Plasticity? A Retrospective and Prospective Analysis. Cerebellum (London, England). vol 19. issue 6. 2021-08-19. PMID:32654026. |
is purkinje neuron hyperpolarisation important for cerebellar synaptic plasticity? |
2021-08-19 |
2023-08-13 |
Not clear |
| Margherita De Silva, Javad Sadeghinezhad, Jens R Nyengaard, Mahdi Aghabalazadeh Asl, Ava Saeidi, Nadia De Sordi, Roberto Chiocchetti, Annamaria Grandi. Design-based stereological study of the guinea-pig (Cavia porcellus) cerebellum. Journal of anatomy. vol 239. issue 2. 2021-08-18. PMID:33763861. |
cerebellar total volume, gray and white matter volume fractions, molecular and granular layers volume fractions, cerebellar surface area, purkinje cellular and nuclear volumes, and the purkinje cell total count were stereologically estimated. |
2021-08-18 |
2023-08-13 |
human |
| Margherita De Silva, Javad Sadeghinezhad, Jens R Nyengaard, Mahdi Aghabalazadeh Asl, Ava Saeidi, Nadia De Sordi, Roberto Chiocchetti, Annamaria Grandi. Design-based stereological study of the guinea-pig (Cavia porcellus) cerebellum. Journal of anatomy. vol 239. issue 2. 2021-08-18. PMID:33763861. |
the cerebellar surface area was estimated through the use of test lines; purkinje cellular and nuclear volumes were analysed using the nucleator technique, whereas the purkinje cell total count was obtained by means of the optical disector technique. |
2021-08-18 |
2023-08-13 |
human |
| Anton N Shuvaev, Olga S Belozor, Oleg I Mozhei, Elena D Khilazheva, Andrey N Shuvaev, Yana V Fritsler, S Kasparo. Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice. International journal of molecular sciences. vol 22. issue 15. 2021-08-16. PMID:34360588. |
here we induced reactive transformation of cerebellar bergmann glia (bg) using this novel optogenetic approach and tested whether memantine could counteract changes in bg and purkinje cell (pc) morphology and expression of the main glial glutamate transporter-excitatory amino acid transporter 1 (eaat1). |
2021-08-16 |
2023-08-13 |
mouse |
| Jan Voog. The Theories of Gerbrandus Jelgersma (1859-1942) on the Function of the Cerebellum. Cerebellum (London, England). 2021-08-12. PMID:34383219. |
both afferent systems of the cerebellum, the mossy fiber-parallel fiber system and the climbing fibers terminate on the purkinje cell dendrites. |
2021-08-12 |
2023-08-13 |
Not clear |
| Jan Voog. The Theories of Gerbrandus Jelgersma (1859-1942) on the Function of the Cerebellum. Cerebellum (London, England). 2021-08-12. PMID:34383219. |
when the purkinje cell compares these inputs and notices a difference between instruction and execution, it sends a correction through the descending limb of the superior cerebellar peduncle to the anterior horn cells. |
2021-08-12 |
2023-08-13 |
Not clear |
| Ryaan El-Andari, Felipe Cunha, Barbara Tschirren, Andrew N Iwaniu. Selection for Divergent Reproductive Investment Affects Neuron Size and Foliation in the Cerebellum. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32784306. |
purkinje cell size and cerebellar foliation did not significantly covary with any cerebellar measures, but differed significantly between the selection lines. |
2021-08-10 |
2023-08-13 |
Not clear |
| Ryaan El-Andari, Felipe Cunha, Barbara Tschirren, Andrew N Iwaniu. Selection for Divergent Reproductive Investment Affects Neuron Size and Foliation in the Cerebellum. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32784306. |
these results suggest that within species, the layers of the cerebellum increase in a coordinated fashion, but purkinje cell size and cerebellar foliation do not increase proportionally with overall cerebellum size. |
2021-08-10 |
2023-08-13 |
Not clear |
| Ryaan El-Andari, Felipe Cunha, Barbara Tschirren, Andrew N Iwaniu. Selection for Divergent Reproductive Investment Affects Neuron Size and Foliation in the Cerebellum. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32784306. |
in contrast, selection for differential reproductive investment affects purkinje cell size and cerebellar foliation, but not other quantitative measures of cerebellar anatomy. |
2021-08-10 |
2023-08-13 |
Not clear |
| Ilona Klejbor, Saleh Mahmood, Natalia Melka, Adriana Ebertowska, Janusz Morys, Ewa K Stachowiak, Michal K Stachowiak, Mulchand S Pate. Phenylbutyrate administration reduces changes in the cerebellar Purkinje cells population in PDC‑deficient mice. Acta neurobiologiae experimentalis. vol 80. issue 3. 2021-08-04. PMID:32990288. |
in contrast, administration of phenylbutyrate variably lessened the ill effects of pdc deficiency on purkinje cell populations in different areas of the cerebellum. |
2021-08-04 |
2023-08-13 |
mouse |
| Carrie Sheeler, Juao-Guilherme Rosa, Ella Borgenheimer, Aaron Mellesmoen, Orion Rainwater, Marija Cvetanovi. Post-symptomatic Delivery of Brain-Derived Neurotrophic Factor (BDNF) Ameliorates Spinocerebellar Ataxia Type 1 (SCA1) Pathogenesis. Cerebellum (London, England). vol 20. issue 3. 2021-07-31. PMID:33394333. |
expression of brain-derived neurotrophic factor (bdnf), growth factor important for the survival and function of cerebellar neurons, is decreased in atxn1[82q] mice, the purkinje neuron specific transgenic mouse model of sca1. |
2021-07-31 |
2023-08-13 |
mouse |
| Qinji Zhou, Jingwen Qin, Yaying Liang, Wei Zhang, Siyuan He, Fadel Tissir, Yibo Qu, Libing Zho. Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity. iScience. vol 24. issue 7. 2021-07-27. PMID:34308297. |
celsr3 is required for purkinje cell maturation and regulates cerebellar postsynaptic plasticity. |
2021-07-27 |
2023-08-13 |
Not clear |
| Daneck Lang-Ouellette, Kim M Gruver, Amy Smith-Dijak, François G C Blot, Chloe A Stewart, Pauline de Vanssay de Blavous, Connie H Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L Faust, Martijn Schonewille, Alanna J Wat. Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function. Nature communications. vol 12. issue 1. 2021-07-26. PMID:34226561. |
purkinje cell axonal swellings enhance action potential fidelity and cerebellar function. |
2021-07-26 |
2023-08-13 |
mouse |
| Daneck Lang-Ouellette, Kim M Gruver, Amy Smith-Dijak, François G C Blot, Chloe A Stewart, Pauline de Vanssay de Blavous, Connie H Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L Faust, Martijn Schonewille, Alanna J Wat. Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function. Nature communications. vol 12. issue 1. 2021-07-26. PMID:34226561. |
axonal swellings have been found on purkinje cell axons in the cerebellum both in healthy development and in neurodegenerative diseases, and computational models predicts that axonal swellings impair axonal function. |
2021-07-26 |
2023-08-13 |
mouse |
| Min-Min Lou, Xiao-Qiang Tang, Guang-Ming Wang, Jia He, Fang Luo, Ming-Feng Guan, Fei Wang, Huan Zou, Jun-Ying Wang, Qun Zhang, Ming-Jian Xu, Qi-Li Shi, Li-Bing Shen, Guo-Ming Ma, Yi Wu, Yao-Yang Zhang, Ai-Bin Liang, Ting-Hua Wang, Liu-Lin Xiong, Jian Wang, Jun Xu, Wen-Yuan Wan. Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons. Nature communications. vol 12. issue 1. 2021-07-22. PMID:34210972. |
bs-drl1 mediated ddr exhibits cell-type specificity in the cortex and cerebellum in gamma-irradiated mice and bs-drl1 knockout mice show impaired motor function and concomitant purkinje cell degeneration. |
2021-07-22 |
2023-08-13 |
mouse |
| Esther Suk King Lai, Hisako Nakayama, Taisuke Miyazaki, Takanobu Nakazawa, Katsuhiko Tabuchi, Kouichi Hashimoto, Masahiko Watanabe, Masanobu Kan. An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:34262438. |
functional magnetic resonance imaging and examination of post-mortem brain in asd patients implicate alteration of cerebellar morphology and purkinje cell (pc) loss. |
2021-07-16 |
2023-08-13 |
mouse |
| Sabine C Winkler, Etsuko Shimobayashi, Josef P Kapfhamme. PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32860158. |
in a transgenic mouse model of sca14 expressing the human s361g mutation, purkinje cell dendritic development is impaired in cerebellar slice cultures similar to pharmacological activation of pkc. |
2021-07-01 |
2023-08-13 |
mouse |
| Sabine C Winkler, Etsuko Shimobayashi, Josef P Kapfhamme. PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32860158. |
mirna-mediated crmp2 knockdown decreased purkinje cell dendritic outgrowth in dissociated cerebellar cultures as did the transfection of crmp2 mutants with a modified thr555 site. |
2021-07-01 |
2023-08-13 |
mouse |
| Khoa Tran-Anh, Jingyun Zhang, Viet Tuan Nguyen-Minh, Hirofumi Fujita, Tatsumi Hirata, Izumi Sugihar. Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. vol 7. issue 6. 2021-06-18. PMID:33055198. |
common origin of the cerebellar dual somatotopic areas revealed by tracking embryonic purkinje cell clusters with birthdate tagging. |
2021-06-18 |
2023-08-13 |
Not clear |
| Khoa Tran-Anh, Jingyun Zhang, Viet Tuan Nguyen-Minh, Hirofumi Fujita, Tatsumi Hirata, Izumi Sugihar. Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. vol 7. issue 6. 2021-06-18. PMID:33055198. |
as developing pcs guide formation of the module-specific proper neuronal circuits in the cerebellum, we hypothesized that the rearrangement of embryonic purkinje cell (pc) clusters shapes the adult cerebellar compartmentalization. |
2021-06-18 |
2023-08-13 |
Not clear |