| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Osamu Hoshino, Meihong Zheng, Yasuhiro Fukuok. Effect of cortical extracellular GABA on motor response. Journal of computational neuroscience. 2022-06-13. PMID:35695984. |
the flattening of sensory tuning in [formula: see text] caused by decreasing the concentration of gamma-aminobutyric acid (gaba) in extracellular space resulted in a decrease in the stimulus-sensitive [formula: see text] pyramidal cell activity while increasing the stimulus-insensitive [formula: see text] pyramidal cell activity, thereby prolonging the reaction time of mns to the applied feature stimulus. |
2022-06-13 |
2023-08-14 |
Not clear |
| Barna Dudok, Miklos Szoboszlay, Anirban Paul, Peter M Klein, Zhenrui Liao, Ernie Hwaun, Gergely G Szabo, Tristan Geiller, Bert Vancura, Bor-Shuen Wang, Sam McKenzie, Jesslyn Homidan, Lianne M F Klaver, Daniel F English, Z Josh Huang, György Buzsáki, Attila Losonczy, Ivan Soltes. Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior. Neuron. vol 109. issue 23. 2021-12-05. PMID:34648750. |
although aacs are the only cellular source of gaba targeting the initial segment, their in vivo activity patterns and influence over pyramidal cell dynamics are not well understood. |
2021-12-05 |
2023-08-13 |
mouse |
| Seham Alaiyed, Mondona McCann, Gouri Mahajan, Grazyna Rajkowska, Craig A Stockmeier, Kenneth J Kellar, Jian Young Wu, Katherine Conan. Venlafaxine Stimulates an MMP-9-Dependent Increase in Excitatory/Inhibitory Balance in a Stress Model of Depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 22. 2020-10-22. PMID:32269106. |
since parvalbumin-expressing interneurons are the predominant cell population that is enveloped by pnns, which enhance their ability to release gaba, excess pnn deposition likely increases pyramidal cell inhibition. |
2020-10-22 |
2023-08-13 |
mouse |
| Hyunjung Oh, Sean C Piantadosi, Brad R Rocco, David A Lewis, Simon C Watkins, Etienne Sibill. The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression. Biological psychiatry. vol 85. issue 6. 2020-02-03. PMID:30449530. |
a parallel downregulation of brain-derived neurotrophic factor (bdnf) and somatostatin (sst), a marker of inhibitory gamma-aminobutyric acid interneurons that target pyramidal cell dendrites, has been reported in several brain areas of subjects with major depressive disorder (mdd). |
2020-02-03 |
2023-08-13 |
human |
| Jinhong Jiang, Yali Peng, Zhen He, Lijuan Wei, Weidong Jin, Xiaoli Wang, Min Chan. Intrahippocampal injection of Cortistatin-14 impairs recognition memory consolidation in mice through activation of sst Brain research. vol 1666. 2018-03-13. PMID:28477863. |
in the hippocampus, cst-14 inhibits ca1 neuronal pyramidal cell firing and co-exists with gaba. |
2018-03-13 |
2023-08-13 |
mouse |
| James M Otis, Kidane B Dashew, Devin Muelle. Neurobiological dissociation of retrieval and reconsolidation of cocaine-associated memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 3. 2013-04-01. PMID:23325262. |
using patch-clamp electrophysiology, we also show that application of a β-ar antagonist prevents norepinephrine-induced potentiation of pl-mpfc pyramidal cell and γ-aminobutyric-acid (gaba) interneuron excitability. |
2013-04-01 |
2023-08-12 |
rat |
| Laia Lladó-Pelfort, Noemí Santana, Valentina Ghisi, Francesc Artigas, Pau Celad. 5-HT1A receptor agonists enhance pyramidal cell firing in prefrontal cortex through a preferential action on GABA interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21893679. |
5-ht1a receptor agonists enhance pyramidal cell firing in prefrontal cortex through a preferential action on gaba interneurons. |
2012-11-13 |
2023-08-12 |
rat |
| Jill R Glausier, David A Lewi. Selective pyramidal cell reduction of GABA(A) receptor α1 subunit messenger RNA expression in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 10. 2012-06-04. PMID:21677653. |
selective pyramidal cell reduction of gaba(a) receptor α1 subunit messenger rna expression in schizophrenia. |
2012-06-04 |
2023-08-12 |
human |
| Jill R Glausier, David A Lewi. Selective pyramidal cell reduction of GABA(A) receptor α1 subunit messenger RNA expression in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 10. 2012-06-04. PMID:21677653. |
these results suggest that pyramidal cell inhibition is reduced in schizophrenia, whereas inhibition of gaba neurons is maintained. |
2012-06-04 |
2023-08-12 |
human |
| Douglas Bennion, Tyron Jensen, Curtis Walther, John Hamblin, Andrew Wallmann, Jason Couch, Jacob Blickenstaff, Michael Castle, Lauren Dean, Sam Beckstead, Collin Merrill, Casey Muir, Teresa St Pierre, Bryan Williams, Stephen Daniel, Jeffrey G Edward. Transient receptor potential vanilloid 1 agonists modulate hippocampal CA1 LTP via the GABAergic system. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21645527. |
using field electrophysiology in hippocampal ca1 stratum radiatum we investigated how trpv1 agonists modulate ltp, low frequency stimulation-induced ltd, and (rs)-3,5-dihydroxyphenylglycine (dhpg)-induced ltd. first we confirmed that trpv1 agonists induce enhancement of ca1 pyramidal cell ltp in the absence the gaba(a) receptor antagonist picrotoxin. |
2012-05-25 |
2023-08-12 |
Not clear |
| Steve Gibbs, Bidisha Chattopadhyaya, Sébastien Desgent, Patricia N Awad, Olivier Clerk-Lamalice, Maxime Levesque, Rose-Mari Vianna, Rose-Marie Rébillard, Andrée-Anne Delsemme, David Hébert, Luc Tremblay, Martin Lepage, Laurent Descarries, Graziella Di Cristo, Lionel Carman. Long-term consequences of a prolonged febrile seizure in a dual pathology model. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21406232. |
a reduction of hippocampal volume on the side of the lesion preceded the srs and was associated with a loss of hippocampal neurons, a marked decrease in pyramidal cell spine density, an increase in the hippocampal levels of nmda receptor nr2a subunit, but no significant change in gaba receptors. |
2012-05-07 |
2023-08-12 |
rat |
| L Vivash, A Tostevin, D S H Liu, L Dalic, S Dedeurwaerdere, R J Hicks, D A Williams, D E Myers, T J O'Brie. Changes in hippocampal GABAA/cBZR density during limbic epileptogenesis: relationship to cell loss and mossy fibre sprouting. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:20816783. |
the temporal evolution of gaba(a)/cbzr density changes post-ka-induced se, and the relationship with decreases in hippocampal pyramidal cell numbers and mfs, may point to a key role for these changes in the pathogenesis of acquired limbic epileptogenesis. |
2011-11-22 |
2023-08-12 |
human |
| Florian Bähner, Elisa K Weiss, Gunnar Birke, Nikolaus Maier, Dietmar Schmitz, Uwe Rudolph, Michael Frotscher, Roger D Traub, Martin Both, Andreas Draguh. Cellular correlate of assembly formation in oscillating hippocampal networks in vitro. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 35. 2011-11-08. PMID:21768381. |
gaba(a) receptors had a dual role in pyramidal cell recruitment. |
2011-11-08 |
2023-08-12 |
mouse |
| Fumiko Arima-Yoshida, Ayako M Watabe, Toshiya Manab. The mechanisms of the strong inhibitory modulation of long-term potentiation in the rat dentate gyrus. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21535245. |
although ltp in both perforant path-dentate gyrus (dg) granule cell and ca3-ca1 pyramidal cell synapses is similarly dependent on activation of postsynaptic n-methyl-d-aspartate receptors, several reports suggest that modulation of ltp by γ-aminobutyric acid (gaba) receptor-mediated inhibitory inputs is stronger in perforant path-dg granule cell synapses. |
2011-09-16 |
2023-08-12 |
rat |
| Clotilde Lecrux, Xavier Toussay, Ara Kocharyan, Priscilla Fernandes, Sujay Neupane, Maxime Lévesque, Fabrice Plaisier, Amir Shmuel, Bruno Cauli, Edith Hame. Pyramidal neurons are "neurogenic hubs" in the neurovascular coupling response to whisker stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734275. |
these results demonstrate that changes in pyramidal cell activity, sculpted by specific types of inhibitory gaba interneurons, drive the cbf response to whisker stimulation and, further, that metabolically active astrocytes are also required. |
2011-09-09 |
2023-08-12 |
rat |
| Stephen I Deutsch, Richard B Rosse, Barbara L Schwartz, John Mastropaolo, Jessica A Burket, Abraham Weizma. Regulation of intermittent oscillatory activity of pyramidal cell neurons by GABA inhibitory interneurons is impaired in schizophrenia: rationale for pharmacotherapeutic GABAergic interventions. The Israel journal of psychiatry and related sciences. vol 47. issue 1. 2011-02-18. PMID:20686196. |
regulation of intermittent oscillatory activity of pyramidal cell neurons by gaba inhibitory interneurons is impaired in schizophrenia: rationale for pharmacotherapeutic gabaergic interventions. |
2011-02-18 |
2023-08-12 |
Not clear |
| Sang-Hun Lee, Csaba Földy, Ivan Soltes. Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534847. |
however, cb(1)r and cck-positive gabaergic terminals are present on pyramidal cell dendrites as well, but the principles of endocannabinoid control of gaba release in dendrites are not understood. |
2010-08-24 |
2023-08-12 |
Not clear |
| Misty M Stafford, Molly N Brown, Puneet Mishra, Gregg D Stanwood, Gregory C Mathew. Glutamate spillover augments GABA synthesis and release from axodendritic synapses in rat hippocampus. Hippocampus. vol 20. issue 1. 2010-03-09. PMID:19338018. |
under conditions of spatially and temporally coordinated release of glutamate and gaba within pyramidal cell dendrites, blocking glial glutamate uptake enhanced quantal release of gaba in a transporter-dependent manner. |
2010-03-09 |
2023-08-12 |
rat |
| Ivan Pavlov, Leonid P Savtchenko, Dimitri M Kullmann, Alexey Semyanov, Matthew C Walke. Outwardly rectifying tonically active GABAA receptors in pyramidal cells modulate neuronal offset, not gain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 48. 2009-12-22. PMID:19955387. |
hippocampal pyramidal cell excitability is regulated both by fast synaptic inhibition and by tonically active high-affinity extrasynaptic gaba(a) receptors. |
2009-12-22 |
2023-08-12 |
Not clear |
| Guillermo Gonzalez-Burgos, Diana C Rotaru, Aleksey V Zaitsev, Nadezhda V Povysheva, David A Lewi. GABA transporter GAT1 prevents spillover at proximal and distal GABA synapses onto primate prefrontal cortex neurons. Journal of neurophysiology. vol 101. issue 2. 2009-03-26. PMID:19073797. |
furthermore, we report that, at least in monkey dlpfc, gat1 similarly restricts gaba spillover onto perisomatic or dendritic inputs, critically controlling the spatiotemporal specificity of inhibitory inputs onto proximal or distal compartments of the pyramidal cell membrane. |
2009-03-26 |
2023-08-12 |
rat |