| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling Wang, Sutong Wang, Weiyi Mo, Yaqing Li, Qing Yang, Yutao Tian, Chenguang Zheng, Jiajia Yang, Dong Min. Ultrasound stimulation attenuates CRS-induced depressive behavior by modulating dopamine release in the prefrontal cortex. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2024-03-19. PMID:38498742. |
these beneficial effects of fus might be due to protection in the da neuron of vta. |
2024-03-19 |
2024-03-21 |
human |
| Harris E Blankenship, Kelsey A Carter, Nina T Cassidy, Andrea N Markiewicz, Michael I Thellmann, Amanda L Sharpe, Willard M Freeman, Michael J Beckstea. VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014232. |
we found deficits in reward-based operant learning in ad mice, suggesting possible vta da neuron dysregulation. |
2023-11-28 |
2023-11-29 |
mouse |
| Millie Rincón-Cortés, Anthony A Grac. Sex-dependent emergence of prepubertal social dysfunction and augmented dopamine activity in a neurodevelopmental rodent model relevant for schizophrenia. Schizophrenia research. vol 262. 2023-11-03. PMID:37922841. |
male mam rats exhibited reduced social approach and increased vta da neuron activity compared to saline-treated (sal) males, whereas female mam rats exhibited enhanced play behaviors compared to sal females but no changes in social approach or vta population activity during this period. |
2023-11-03 |
2023-11-08 |
rat |
| Emily M Black, Shanna B Samels, Wei Xu, Jessica R Barson, Caroline E Bass, Sandhya Kortagere, Rodrigo A Españ. Hypocretin / Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and Motivation for Cocaine. Addiction neuroscience. vol 7. 2023-10-20. PMID:37854172. |
for example, hcrt drives vta da neuron activity and enhances the effects of cocaine on da transmission, while disrupting hcrtr1 attenuates da responses to cocaine. |
2023-10-20 |
2023-11-08 |
rat |
| E Liu, Kunkun Pang, Min Liu, Xu Tan, Zhaofang Hang, Shouhong Mu, Weikai Han, Qingwei Yue, Stefano Comai, Jinhao Su. Activation of Kv7 channels normalizes hyperactivity of the VTA-NAcLat circuit and attenuates methamphetamine-induced conditioned place preference and sensitization in mice. Molecular psychiatry. 2023-08-21. PMID:37604975. |
as different dopamine (da) neuron subpopulations in the vta participate in different neuronal circuits, it is a challenge to isolate these da neuron subtypes. |
2023-08-21 |
2023-09-07 |
mouse |
| Claudia Esposito-Zapero, Sandra Fernández-Rodríguez, María José Sánchez-Catalán, Teodoro Zornoza, María José Cano-Cebrián, Luis Graner. The rostromedial tegmental nucleus RMTg is not a critical site for ethanol-induced motor activation in rats. Psychopharmacology. 2023-07-20. PMID:37474756. |
it is well demonstrated that ethanol, like opioid drugs, provokes vta da neuron disinhibition by interacting (through its secondary metabolite, salsolinol) with mors present in vta gaba interneurons, but it is not known whether ethanol could disinhibit vta da neurons through the mors present in the rmtg/tvta. |
2023-07-20 |
2023-08-14 |
rat |
| Sarthak M Singhal, Vivien Zell, Lauren Faget, Lauren M Slosky, Lawrence S Barak, Marc G Caron, Anthony B Pinkerton, Thomas S Hnask. Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens. Neuropharmacology. 2023-04-13. PMID:37055008. |
strong expression of the g protein-coupled receptor (gpcr) neurotensin receptor 1 (ntr1) in ventral tegmental area (vta) dopamine (da) neurons and terminals makes it an attractive target to modulate da neuron activity and normalize da-related pathologies. |
2023-04-13 |
2023-08-14 |
mouse |
| María Villa, María Martínez-Vega, Aarón Del Pozo, Itziar Muneta-Arrate, Ana Gómez-Soria, Carolina Muguruza, María de Hoz-Rivera, Angela Romero, Laura Silva, Luis F Callado, Maria José Casarejos, José Martínez-Orgad. The Role of the Dopamine System in Post-Stroke Mood Disorders in Newborn Rats. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36834637. |
da neuron density in the ventral tegmental area, brain da concentration and da transporter (dat) expression as well as d2 receptor (d2r) expression and g-protein functional coupling were also studied. |
2023-02-25 |
2023-08-14 |
rat |
| Millie Rincón-Cortés, Anthony A Grac. Dopamine downregulation in novel rodent models useful for the study of postpartum depression. Frontiers in behavioral neuroscience. vol 16. 2023-01-09. PMID:36620861. |
we also present two novel rodent models based on postpartum adversity exposure (i.e., pup removal, scarcity-adversity) which result in ppd-relevant behavioral changes (e.g., disrupted mother-infant interactions, deficits in maternal behavior, depressive-like phenotypes) and attenuated ventral tegmental area (vta) da neuron activity consistent with a hypodopaminergic state. |
2023-01-09 |
2023-08-14 |
human |
| Yunyao Xie, Longwen Huang, Alberto Corona, Alexa H Pagliaro, Stephen D She. A dopaminergic reward prediction error signal shapes maternal behavior in mice. Neuron. 2022-12-21. PMID:36543170. |
trial-by-trial performance was correlated with the history of da neuron activity, but da signals were inconsistent with vta directly influencing the current trial. |
2022-12-21 |
2023-08-14 |
mouse |
| J Daniel Obray, Christina A Small, Emily K Baldwin, Eun Young Jang, Jin Gyeom Lee, Chae Ha Yang, Jordan T Yorgason, Scott C Steffense. Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine. Frontiers in cellular neuroscience. vol 16. 2022-07-29. PMID:35903367. |
pretreatment with domperidone, a peripheral-only da d2 receptor (d2r) antagonist, reduced intravenous da mediated increases in vta da neuron activity and nac da levels. |
2022-07-29 |
2023-08-14 |
Not clear |
| Daniela L Uliana, Felipe V Gomes, Anthony A Grac. Nucleus reuniens inactivation reverses stress-induced hypodopaminergic state and altered hippocampal-accumbens synaptic plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-04-29. PMID:35488085. |
the stress exposure increased the immobility in the fst and decreased vta da neuron population activity. |
2022-04-29 |
2023-08-13 |
rat |
| Millie Rincón-Cortés, Anthony A Grac. Adult stress exposure blunts dopamine system hyperresponsivity in a neurodevelopmental rodent model of schizophrenia. NPJ schizophrenia. vol 8. issue 1. 2022-03-26. PMID:35338155. |
mam rats exhibited a reduction in social approach and increased vta da neuron activity compared to sal rats or cms groups. |
2022-03-26 |
2023-08-13 |
rat |
| Millie Rincón-Cortés, Anthony A Grac. Adult stress exposure blunts dopamine system hyperresponsivity in a neurodevelopmental rodent model of schizophrenia. NPJ schizophrenia. vol 8. issue 1. 2022-03-26. PMID:35338155. |
apomorphine administration results were consistent with the model suggesting that reductions in vta da neuron activity in mam rats following fst exposure resulted from over-excitation, or depolarization block. |
2022-03-26 |
2023-08-13 |
rat |
| Johannes W de Jong, Kurt M Fraser, Stephan Lamme. Mesoaccumbal Dopamine Heterogeneity: What Do Dopamine Firing and Release Have to Do with It? Annual review of neuroscience. 2022-02-28. PMID:35226827. |
this contrast between heterogeneous functions of da release versus a homogeneous role for da neuron activity raises numerous questions regarding how vta da activity translates into nac da release. |
2022-02-28 |
2023-08-13 |
Not clear |
| Anne-Emilie Allain, Oceane Aribo, Maria-Carmen Medrano, Marie-Line Fournier, Sandrine S Bertrand, Stephanie Caill. Impact of acute and chronic nicotine administration on midbrain dopaminergic neuron activity and related behaviors in TRPV1 knock-out juvenile mice. The European journal of neuroscience. 2021-12-23. PMID:34939238. |
in conclusion, trpv1rs modulate nicotine-induced psychomotor sensitization in mice independently of a control on vta da neuron activity. |
2021-12-23 |
2023-08-13 |
mouse |
| Nitsan Goldstein, Jamie R E Carty, J Nicholas Betle. Specificity of varenicline in blocking mesolimbic circuit activation to natural and drug rewards. Neuroscience. 2021-12-19. PMID:34923039. |
we demonstrate that varenicline pretreatment enhances the suppression of nicotine-evoked da release by attenuating da neuron activity in the vta. |
2021-12-19 |
2023-08-13 |
mouse |
| Clément Solié, Benoit Girard, Beatrice Righetti, Malika Tapparel, Camilla Bellon. VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error. Nature neuroscience. 2021-12-03. PMID:34857949. |
using a social instrumental task, we then show that vta da neuron activity encodes social prediction error and drives social reinforcement learning. |
2021-12-03 |
2023-08-13 |
mouse |
| Susan F Sonnenschein, Anthony A Grac. Peripubertal mGluR2/3 Agonist Treatment Prevents Hippocampal Dysfunction and Dopamine System Hyperactivity in Adulthood in MAM Model of Schizophrenia. Schizophrenia bulletin. vol 47. issue 6. 2021-12-02. PMID:33928393. |
in either late adolescence (pd 47-56) or adulthood (pd 83-96), novel object recognition (nor) was tested, followed by anesthetized in vivo electrophysiological recordings of vta da neuron activity or ventral hippocampal (vhpc) pyramidal neuron activity. |
2021-12-02 |
2023-08-13 |
rat |
| Ludi Zhang, Jing Wang, Chenxu Niu, Yu Zhang, Tiantian Zhu, Dongyang Huang, Jing Ma, Hui Sun, Nikita Gamper, Xiaona Du, Hailin Zhan. Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice. Cell reports. vol 37. issue 5. 2021-11-17. PMID:34731609. |
in parallel, we observe increased activity of the dopaminergic (da) neuron in the midbrain ventral tegmental area (vta), and inhibition of this elevated vta da neuron activity reverses the behavioral manifestations of depression. |
2021-11-17 |
2023-08-13 |
mouse |