| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nobuo Tsuboi, Tetsuya Kawamura, Takeo Ishii, Tatsuo Hosoy. Obesity-related nephropathy associated with a history of IgA nephropathy. Internal medicine (Tokyo, Japan). vol 47. issue 19. 2009-01-28. PMID:18827422. |
instead, a marked decrease in the glomerular density and hypertrophy of the remnant glomeruli were noted. |
2009-01-28 |
2023-08-12 |
Not clear |
| Shu Liu, Lihua Shi, Shuxia Wan. Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury. American journal of physiology. Renal physiology. vol 293. issue 5. 2007-12-18. PMID:17881461. |
these mice also exhibited glomerular hypertrophy, accompanied by increased tsp1, active tgf-beta, fibronectin accumulation in the glomeruli compared with control wt littermates. |
2007-12-18 |
2023-08-12 |
mouse |
| Enqi Liu, Masatoshi Morimoto, Shuji Kitajima, Tomonari Koike, Ying Yu, Hideo Shiiki, Michio Nagata, Teruo Watanabe, Jianglin Fa. Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions. Journal of the American Society of Nephrology : JASN. vol 18. issue 7. 2007-10-30. PMID:17554151. |
this study provides the first evidence that increased expression of vegf in glomeruli directly causes the glomerular hypertrophy that is associated with proteinuria, suggesting that vegf exerts multiple effects on the glomerular pathophysiologic processes. |
2007-10-30 |
2023-08-12 |
human |
| Jin-Ju Kim, Jin Ji Li, Dong-Sub Jung, Seung-Jae Kwak, Dong-Ryeol Ryu, Tae-Hyun Yoo, Seung Hyeok Han, Hoon Young Choi, Hyung Jong Kim, Dae Suk Han, Shin-Wook Kan. Differential expression of nephrin according to glomerular size in early diabetic kidney disease. Journal of the American Society of Nephrology : JASN. vol 18. issue 8. 2007-09-26. PMID:17599973. |
glomerular hypertrophy occurs in dn, yet hypertrophy does not develop in all glomeruli concurrently. |
2007-09-26 |
2023-08-12 |
rat |
| Masumi Yoshida, Hitoshi Kimura, Kouhei Kyuki, Mikio It. Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet. European journal of pharmacology. vol 548. issue 1-3. 2006-12-12. PMID:16979162. |
furthermore, glycogen degeneration of distal tubules, fatty degeneration of glomerular endothelium, and hypertrophy of glomeruli and mesangium were observed in the kidneys of the diabetic animals, when histopathological evaluation was performed at 4, 8 and 15 weeks (glomerular and mesangial hypertrophy was observed only at 15 weeks). |
2006-12-12 |
2023-08-12 |
rat |
| Lenin Mahimainathan, Falguni Das, Balachandar Venkatesan, Goutam Ghosh Choudhur. Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN. Diabetes. vol 55. issue 7. 2006-08-14. PMID:16804083. |
we link early renal hypertrophy with significant reduction in pten expression in the streptozotocin-induced diabetic kidney cortex and glomeruli, concomitant with activation of akt. |
2006-08-14 |
2023-08-12 |
mouse |
| Hirofumi Matsuoka, Yuichi Nakashima, Kazuhiro Oshim. Prognostic significance of the number of renal glomeruli in reflux nephropathy. BJU international. vol 98. issue 1. 2006-07-25. PMID:16831164. |
to monitor the decrease in the number of glomeruli in reflux nephropathy (rn) and to investigate its association with glomerular hypertrophy or clinical data, as some cases of rn progress to end-stage renal failure, although the mechanism of progression remains unknown and is generally thought to depend on remnant normal renal tissue mass, i.e. |
2006-07-25 |
2023-08-12 |
Not clear |
| Rebecca N Douglas-Denton, Bridgette J McNamara, Wendy E Hoy, Michael D Hughson, John F Bertra. Does nephron number matter in the development of kidney disease? Ethnicity & disease. vol 16. issue 2 Suppl 2. 2006-07-21. PMID:16774009. |
low nephron number is frequently, but not always, associated with hypertrophy of remaining glomeruli. |
2006-07-21 |
2023-08-12 |
human |
| Yongman Lv, Junwu Dong, Xiaochun Niu, Xiaocheng Li. Renoprotective effect of benazepril on diabetic nephropathy mediated by P42/44MAPK. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 1. 2006-05-30. PMID:15934302. |
there were glomeruli hypertrophy and slight or moderate mesangium proliferation in diabetic rats, while there was fragmentally proliferative mesangium in group c at the end of the 8th week. |
2006-05-30 |
2023-08-12 |
rat |
| Yongman Lv, Junwu Dong, Xiaochun Niu, Xiaocheng Li. Renoprotective effect of benazepril on diabetic nephropathy mediated by P42/44MAPK. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 1. 2006-05-30. PMID:15934302. |
benazepril can eliminate high filtration of glomeruli, decrease proteinuria, and eliminate renal hypertrophy as well as renal destruction. |
2006-05-30 |
2023-08-12 |
rat |
| G S Hill, D Heudes, C Jacquot, E Gauthier, J Bariét. Morphometric evidence for impairment of renal autoregulation in advanced essential hypertension. Kidney international. vol 69. issue 5. 2006-05-24. PMID:16518341. |
glomeruli were divided into four basic types: normal, hypertrophic, focal segmental glomerulosclerosis (fsgs) type, and sclerosing. |
2006-05-24 |
2023-08-12 |
Not clear |
| G S Hill, D Heudes, C Jacquot, E Gauthier, J Bariét. Morphometric evidence for impairment of renal autoregulation in advanced essential hypertension. Kidney international. vol 69. issue 5. 2006-05-24. PMID:16518341. |
this increase was due primarily to an increase in size of each type, for example, for hypertrophic glomeruli: total capillary area (22 205+/-10 426 vs 15 349+/-4577 microm(2), p=0.0038). |
2006-05-24 |
2023-08-12 |
Not clear |
| Jocelyn E Wiggins, Meera Goyal, Silja K Sanden, Bryan L Wharram, Kerby A Shedden, David E Misek, Rork D Kuick, Roger C Wiggin. Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. Journal of the American Society of Nephrology : JASN. vol 16. issue 10. 2006-03-30. PMID:16120818. |
hypertrophy above a certain threshold was associated with podocyte stress and then failure, culminating in reduced podocyte numbers in sclerotic glomeruli. |
2006-03-30 |
2023-08-12 |
rat |
| Maurice Bichara, Amel Attmane-Elakeb, Dennis Brown, Marie Essig, Zoubida Karim, Martine Muffat-Joly, Laetitia Micheli, Isabelle Eude-Le Parco, Françoise Cluzeaud, Michel Peuchmaur, Jean-Pierre Bonvalet, Françoise Poirier, Nicolette Farma. Exploring the role of galectin 3 in kidney function: a genetic approach. Glycobiology. vol 16. issue 1. 2006-03-01. PMID:16166603. |
compared to wt mice, gal 3-/- mice had approximately 11% fewer glomeruli (p < 0.04), associated with kidney hypertrophy (p < 0.006). |
2006-03-01 |
2023-08-12 |
mouse |
| Masumi Yoshida, Hitoshi Kimura, Kouhei Kyuki, Mikio It. Effect of combined vitamin E and insulin administration on renal damage in diabetic rats fed a high cholesterol diet. Biological & pharmaceutical bulletin. vol 28. issue 11. 2005-12-21. PMID:16272693. |
furthermore, glycogen degeneration of distal tubules, fatty degeneration of glomerular endothelium and hypertrophy of glomeruli and mesangium were observed in the kidneys of the diabetic animals when histopathological evaluation was performed at 4, 8, and 15 weeks (glomerular and mesangial hypertrophy were observed only at 15 weeks). |
2005-12-21 |
2023-08-12 |
rat |
| Zheng Feng, Anna Rita Plati, Qing-li Cheng, Mariana Berho, Anita Banerjee, Mylene Potier, Wen-che Jy, Andrew Koff, Liliane J Striker, Gary E Strike. Glomerular aging in females is a multi-stage reversible process mediated by phenotypic changes in progenitors. The American journal of pathology. vol 167. issue 2. 2005-09-29. PMID:16049323. |
the glomeruli of postmenopausal c57bl6 mice, and age-matched males, show progressive hypertrophy and glomerulosclerosis. |
2005-09-29 |
2023-08-12 |
mouse |
| Ruth Rasch, Finn Lauszus, Jesper Skovhus Thomsen, Allan Flyvbjer. Glomerular structural changes in pregnant, diabetic, and pregnant-diabetic rats. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 113. issue 7-8. 2005-09-13. PMID:16086816. |
enlargement of glomeruli in diabetes involves hypertrophy and hyperplasia concurrent with several morphological changes within the glomerulus. |
2005-09-13 |
2023-08-12 |
rat |
| Kosuke Okada, Naoko Ishikawa, Kouichiro Fujimori, Masanobu Goryo, Manabu Ikeda, Jun Sasaki, Daisaku Watanabe, Akiko Takasuga, Takashi Hirano, Yoshikazu Sugimot. Abnormal development of nephrons in claudin-16-defective Japanese black cattle. The Journal of veterinary medical science. vol 67. issue 2. 2005-04-18. PMID:15750313. |
histopathological examination of the kidneys showed reduction in the number of glomeruli, compensatory hypertrophy of glomeruli and tubules, and glomerular and tubular atrophy accompanied by interstitial fibrosis and lymphocytic infiltration. |
2005-04-18 |
2023-08-12 |
cattle |
| Jorge R Almeida, Carlos A Mandarim-de-Lacerd. Maternal gestational protein-calorie restriction decreases the number of glomeruli and causes glomerular hypertrophy in adult hypertensive rats. American journal of obstetrics and gynecology. vol 192. issue 3. 2005-04-01. PMID:15746696. |
maternal gestational protein-calorie restriction decreases the number of glomeruli and causes glomerular hypertrophy in adult hypertensive rats. |
2005-04-01 |
2023-08-12 |
rat |
| Peter Martinka, Jens Fielitz, Andreas Patzak, Vera Regitz-Zagrosek, Pontus B Persson, Harald M Staus. Mechanisms of blood pressure variability-induced cardiac hypertrophy and dysfunction in mice with impaired baroreflex. American journal of physiology. Regulatory, integrative and comparative physiology. vol 288. issue 3. 2005-03-29. PMID:15563577. |
adrenal tyrosine hydroxylase protein content and the number of renin-positive glomeruli were not different, suggesting that sympathetic activation and the systemic renin-angiotensin system did not contribute to cardiac hypertrophy. |
2005-03-29 |
2023-08-12 |
mouse |