| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isabelle M Renaud, Angele Chainey, Marie-France Belair, Chantal Mandet, Odile Michel, Isaac Myara, Jacques Chevalier, Gerard E Plant. Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination. Fundamental & clinical pharmacology. vol 18. issue 4. 2004-12-09. PMID:15312150. |
the hypertrophy of superficial glomeruli and the mesangial expansion of deep glomeruli observed in control rats were reduced in per/ind-treated obese rats. |
2004-12-09 |
2023-08-12 |
rat |
| Yong-Jin Kim, Yong-Lim Ki. A case of chronic renal allograft failure by effects of elderly donor. Clinical transplantation. vol 16 Suppl 8. 2003-04-15. PMID:12464129. |
characteristic microscopic features were: diffuse segmental to global glomerulosclerosis, hypertrophy of non-sclerotic glomerulus, tubular atrophy, arteriolar hyalinosis, interstitial lymphocytic infiltration with tubulitis and anti-iga deposition on glomeruli. |
2003-04-15 |
2023-08-12 |
Not clear |
| C A Mandarim-de-Lacerda, L M Pereir. Renal cortical remodelling by NO-synthesis blockers in rats is prevented by angiotensin-converting enzyme inhibitor and calcium channel blocker. Journal of cellular and molecular medicine. vol 5. issue 3. 2002-07-22. PMID:12067486. |
glomeruli had considerable alterations in l group rats (glomerular hypertrophy or sclerosis) and tubular atrophy. |
2002-07-22 |
2023-08-12 |
rat |
| L Paczek, Z Gaciong, I Bartlomiejczyk, K Sebekova, G Birkenmeier, A Heidlan. Protease administration decreases enhanced transforming growth factor-beta 1 content in isolated glomeruli of diabetic rats. Drugs under experimental and clinical research. vol 27. issue 4. 2002-06-26. PMID:11822224. |
in the present study in streptozotocin-diabetic rats we investigated whether the administration of phlogenzym, a fixed combination of the proteases trypsin and bromelain combined with the antioxidant rutosid, modulates renal hypertrophy and the formation of tgf-beta 1 in isolated glomeruli. |
2002-06-26 |
2023-08-12 |
rat |
| R Osterby, J Tapia, G Nyberg, J Tencer, J Willner, B Rippe, O Torffvi. Renal structures in type 2 diabetic patients with elevated albumin excretion rate. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 109. issue 11. 2002-04-11. PMID:11900054. |
the glomerular hypertrophy is interpreted as a compensatory phenomenon, leading to preservation of filtration surface in the open glomeruli. |
2002-04-11 |
2023-08-12 |
Not clear |
| J Herman, B Van Damme, R Van Damme-Lombaert. Dysplasia of tubular cells in a kidney- transplanted patient treated with recombinant human growth hormone. Pediatric transplantation. vol 5. issue 6. 2002-01-08. PMID:11737773. |
histologically, a progressive increase in the amount of hypertrophy of the tubules and of the glomeruli was seen after initiation of rhgh. |
2002-01-08 |
2023-08-12 |
human |
| F Cornacchia, A Fornoni, A R Plati, A Thomas, Y Wang, L Inverardi, L J Striker, G E Strike. Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors. The Journal of clinical investigation. vol 108. issue 11. 2002-01-03. PMID:11733560. |
clones of recipient glomerular mesangial cells with the donor genotype were found in all +/+ recipients that developed mesangial sclerosis and glomerular hypertrophy, whereas +/+ recipients of +/+ bm had normal glomeruli. |
2002-01-03 |
2023-08-12 |
mouse |
| B Fabris, R Candido, M Carraro, F Fior, M Artero, C Zennaro, M R Cattin, A Fiorotto, M Bortoletto, C Millevoi, M Bardelli, L Faccini, R Carrett. Modulation of incipient glomerular lesions in experimental diabetic nephropathy by hypotensive and subhypotensive dosages of an ACE inhibitor. Diabetes. vol 50. issue 11. 2001-12-07. PMID:11679443. |
in contrast, control of p(alb) in isolated glomeruli exposed to oncotic gradients, proteinuria, and glomerular and tubular hypertrophy was obtained with subhypotensive dosages (dq3 and dq4 groups) of the ace inhibitor. |
2001-12-07 |
2023-08-12 |
rat |
| L C Folmar, G R Gardner, M P Schreibman, L Magliulo-Cepriano, L J Mills, G Zaroogian, R Gutjahr-Gobell, R Haebler, D B Horowitz, N D Denslo. Vitellogenin-induced pathology in male summer flounder (Paralichthys dentatus). Aquatic toxicology (Amsterdam, Netherlands). vol 51. issue 4. 2001-06-28. PMID:11090901. |
the accumulation of vtg, and possibly other estrogen-inducible proteins, resulted in hepatocyte hypertrophy, disruption of spermatogenesis, and obstruction or rupture of renal glomeruli. |
2001-06-28 |
2023-08-12 |
Not clear |
| F Tomoda, M Takata, H Kinuno, S Tomita, K Yasumoto, H Inou. Renal structural properties in prehypertensive Dahl salt-sensitive rats. Hypertension (Dallas, Tex. : 1979). vol 36. issue 1. 2000-10-06. PMID:10904014. |
in conclusion, hypertrophic remodeling without vascular narrowing at preglomerular resistance vessels and structural defects in filtering at the glomeruli could occur in prehypertensive ds rats. |
2000-10-06 |
2023-08-12 |
rat |
| S M Daniele, S Arriaga, S M Martínez, M C Tarrés, S M Montenegro, A E D'Ottavio, N Hisano, J C Picena, L Morisol. Onset and evolution of nephropathy in rats with spontaneous diabetes mellitus. Journal of physiology and biochemistry. vol 56. issue 1. 2000-10-05. PMID:10879681. |
glomeruli showed diffuse hypertrophy of mesangial tissue and thickening of the basement membrane. |
2000-10-05 |
2023-08-12 |
rat |
| M Teschner, A Heidlan. [Lowered intrarenal protein degradation--an alternative path to glomerulosclerosis and tubulo-interstitial fibrosis]. Medizinische Klinik (Munich, Germany : 1983). vol 95. issue 7. 2000-09-13. PMID:10943099. |
the initiating hallmark of nephrosclerosis represents nephronal hypertrophy, due to an accumulation of proteins in the glomeruli and tubulointerstitium. |
2000-09-13 |
2023-08-12 |
Not clear |
| C Sassy-Prigent, D Heudes, C Mandet, M F Bélair, O Michel, B Perdereau, J Bariéty, P Bruneva. Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats. Diabetes. vol 49. issue 3. 2000-07-13. PMID:10868970. |
in parallel, the diabetic glomeruli became hypertrophic with an increase in the mesangial area. |
2000-07-13 |
2023-08-12 |
rat |
| K Sebeková, J Dämmrich, Z Krivosíková, A Heidlan. The effect of oral protease administration in the rat remnant kidney model. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 199. issue 3. 2000-02-14. PMID:10639701. |
the protein/dna ratio in isolated glomeruli and tubules, as an estimate of glomerular matrix accumulation and hypertrophy of tubules, was enhanced in 5/6 nx groups and a tendency towards lower values was observed after e treatment. |
2000-02-14 |
2023-08-12 |
rat |
| P Cortes, B L Riser, J Yee, R G Narin. Mechanical strain of glomerular mesangial cells in the pathogenesis of glomerulosclerosis: clinical implications. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 14. issue 6. 1999-08-05. PMID:10382990. |
in remnant glomeruli, the mechanical stretch is intense, being accounted for largely by the marked glomerular hypertrophy and increased glomerular compliance. |
1999-08-05 |
2023-08-12 |
Not clear |
| N Miyatake, K Shikata, J Wada, H Sugimoto, S Takahashi, H Makin. Differential distribution of insulin-like growth factor-1 and insulin-like growth factor binding proteins in experimental diabetic rat kidney. Nephron. vol 81. issue 3. 1999-05-17. PMID:10050087. |
igf-1 was gradually increased in the glomeruli of diabetic rats and correlated with glomerular hypertrophy. |
1999-05-17 |
2023-08-12 |
rat |
| M Nagata, M Hattori, Y Hamano, K Ito, K Saitoh, T Watanab. Origin and phenotypic features of hyperplastic epithelial cells in collapsing glomerulopathy. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 32. issue 6. 1999-01-04. PMID:9856511. |
the characteristic pathological feature of collapsing glomerulopathy (cg) is marked cell hyperplasia and hypertrophy within the glomeruli. |
1999-01-04 |
2023-08-12 |
Not clear |
| M Nagata, M Hattori, Y Hamano, K Ito, K Saitoh, T Watanab. Origin and phenotypic features of hyperplastic epithelial cells in collapsing glomerulopathy. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 32. issue 6. 1999-01-04. PMID:9856511. |
in collapsed glomeruli, hyperplastic and hypertrophic epithelial cells were frequently connected to pecs and collapsed glomerular basement membranes (gbms). |
1999-01-04 |
2023-08-12 |
Not clear |
| A Abd el-Aal, N H Fare. Renal alterations induced by Cerastes cerastes cerastes venom. Journal of natural toxins. vol 7. issue 1. 1998-09-30. PMID:9689602. |
histological examination of the kidneys in envenomated rats revealed the presence of atrophied glomeruli, cloudy materials within the proximal and distal convoluted tubules, atrophy and hypertrophy of quite a large number of tubular nuclei and mesangial proliferation. |
1998-09-30 |
2023-08-12 |
rat |
| S Oba, K Kimura, N Suzuki, N Mise, A Tojo, K Miyashita, Y Konno, Y Hirata, A Goto, M Omat. Relevance of periglomerular myofibroblasts in progression of human glomerulonephritis. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 32. issue 3. 1998-09-28. PMID:9740158. |
these findings indicate that periglomerular myofibroblasts appeared surrounding the nonsclerotic hypertrophic glomeruli, which may lead finally to glomerulosclerosis. |
1998-09-28 |
2023-08-12 |
human |