All Relations between hypertrophic and matrix compartment

Reference Sentence Publish Date Extraction Date Species
Chen Chen, Xiyu Zhang, Cuiting Zheng, Zhenqiang Gao, Xi Jiang, Yunfei Bai, Yan Men. Sulfasalazine exacerbates Angiotensin II induced cardiac remodeling by activating Akt signal pathway. Clinical and experimental pharmacology & physiology vol issue 2022 35538895 angiotensin ii (ang ii) results in cardiac fibrosis and hypertrophy partly through activation of inflammation, which increases the fibroblasts and promotes extracellular matrix production. 2022-05-11 2022-05-12 Not clear
Abu Mohammad Syed, Sourav Kundu, Chetan Ram, Uttam Kulhari, Akhilesh Kumar, Madhav Nilakanth Mugale, Purusottam Mohapatra, Upadhyayula Suryanarayana Murty, Bidya Dhar Sah. Up-regulation of Nrf2/HO-1 and inhibition of TGF-\\xce\\xb21/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice. Free radical biology & medicine vol issue 2022 35513128 oxidative damage and accumulation of extracellular matrix (ecm) components play a crucial role in the adverse outcome of cardiac hypertrophy. 2022-05-05 2022-05-07 Not clear
Zhaojie Lyu, Yifeng Da, Hongkai Liu, Zhihao Wang, Yong Zhu, Jing Tia. Chsy1 deficiency reduces extracellular matrix productions and aggravates cartilage injury in osteoarthritis. Gene vol issue 2022 35390446 it was found that chsy1 deficiency resulted in a reduction of extracellular matrix production in chondrocytes and a promotion of endochondral osteogenesis, which was indicated by the decreased expression of early chondrocytes genes (col2a1, sox9), and the increased expression of cartilage hypertrophy genes (col10a1, runx2, mmp13, mmp3). 2022-04-07 2022-04-14 Not clear
Yingying Guo, Dan Li, Xian-Feng Cen, Hong-Liang Qiu, Yu-Lan Ma, Yi Liu, Si-Hui Huang, Li-Bo Liu, Man Xu, Qi-Zhu Tan. Diosmetin Protects against Cardiac Hypertrophy via p62/Keap1/Nrf2 Signaling Pathway. Oxidative medicine and cellular longevity vol 2022 issue 2022 35242278 an important pathophysiological consequence of pressure overload-induced cardiac hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes and extracellular matrix. 2022-03-24 2022-03-06 Not clear
Alberto Aimo, Oriol Iborra-Egea, Nicola Martini, Carolina Galvez-Monton, Silvia Burchielli, Giorgia Panichella, Claudio Passino, Michele Emdin, Antoni Bayes-Geni. Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis. Scientific reports vol 12 issue 1 2022 35304529 we identified 6 causative motives of post-mi remodeling (cardiomyocyte cell death, impaired myocyte contractility, extracellular matrix remodeling and fibrosis, hypertrophy, renin-angiotensin-aldosterone system activation, and inflammation), 4 pirfenidone targets and 21 bioflags (indirect effectors). 2022-03-19 2022-04-14 Not clear
Ye Lu, Chengyuan Zhang, Shilin Jiang, Feng Yua. Anti-Dlx5 Retards the Progression of Osteoarthritis through Inhibiting Chondrocyte Hypertrophy and Apoptosis. Evidence-based complementary and alternative medicine : eCAM vol 2022 issue 2022 35280506 the results showed that administration of anti-dlx5 improved pathological changes of osteoarthritis cartilages, characterized by decreased chondrocyte proliferation, chondrocyte hypertrophy, and matrix damage. 2022-03-14 2022-04-14 Not clear
Kimberley C W Wang, Graham M Donovan, Sejal Saglani, Thais Mauad, Alan L James, John G Elliot, Peter B Nobl. Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia. Respirology (Carlton, Vic.) vol issue 2022 35266251 this study characterized thickening of the asm layer from foetal life to childhood and elucidated the underlying mechanism in terms of hypertrophy, hyperplasia and extracellular matrix (ecm) deposition. 2022-03-10 2022-04-14 Not clear
Arijit Bhattacharjee, Dhirendra S Katt. A human osteoarthritis mimicking goat cartilage explant-based disease model for drug screening. ALTEX vol issue 2022 35258089 treatment with il1\xce\xb2 induced oa-like traits in goat cartilage explants and caused a shift in cartilage homeostasis towards enhanced catabolism, resulting in higher matrix degradation, overexpression of degradative and inflammatory mediators and chondrocyte hypertrophy. 2022-03-08 2022-03-09 Not clear
Arijit Bhattacharjee, Dhirendra S Katt. A human osteoarthritis mimicking goat cartilage explant-based disease model for drug screening. ALTEX vol issue 2022 35258089 finally, we evaluated the translational relevance of the developed ex vivo oa model by comparing it with late-stage oa patient samples and observed a striking resemblance in terms of matrix degradation, expression of degradative enzymes, chondrocyte hypertrophy and inflammation. 2022-03-08 2022-03-09 Not clear
Yingying Guo, Dan Li, Xian-Feng Cen, Hong-Liang Qiu, Yu-Lan Ma, Yi Liu, Si-Hui Huang, Li-Bo Liu, Man Xu, Qi-Zhu Tan. Diosmetin Protects against Cardiac Hypertrophy via p62/Keap1/Nrf2 Signaling Pathway. Oxidative medicine and cellular longevity vol 2022 issue 2022 35242278 an important pathophysiological consequence of pressure overload-induced cardiac hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes and extracellular matrix. 2022-03-04 2022-03-06 Not clear
Changshun He, Bo Jiang, Mo Wang, Pengwei Ren, Sae-Il Murtada, Alexander W Caulk, Guangxin Li, Lingfeng Qin, Roland Assi, Constantinos J Lovoulos, Martin A Schwartz, Jay D Humphrey, George Tellide. mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice. JCI insight vol 7 issue 3 2022 35132962 medial thickening results from smooth muscle cell hypertrophy and extracellular matrix accumulation, including matricellular proteins. 2022-02-08 2022-02-13 Not clear
Jan M Leerink, Mabel van de Ruit, Elizabeth A M Feijen, Leontien C M Kremer, Annelies M C Mavinkurve-Groothuis, Yigal M Pinto, Esther E Creemers, Wouter E M Ko. Extracellular matrix remodeling in animal models of anthracycline-induced cardiomyopathy: a meta-analysis. Journal of molecular medicine (Berlin, Germany) vol 99 issue 9 2021 34052857 collagens, matrix metalloproteinases (mmps), inflammation markers, transforming growth factor \xc3\x9f signaling markers, and markers for cardiac hypertrophy were upregulated, whereas the protein kinase b (akt) pro-survival pathway was downregulated. 2022-02-05 2022-01-13 Not clear
Megumi Nakamura, Mu-Chen Yang, Keijyu Ashida, Miyuki Mayanagi, Yasuyuki Sasan. Calcification and resorption of mouse Meckel's cartilage analyzed by von Kossa and tartrate-resistant acid phosphatase histochemistry and scanning electron microscopy/energy-dispersive X-ray spectrometry. Anatomical science international vol issue 2021 34859366 the results demonstrated that the intermediate portion of meckel's cartilage is resorbed by chondroclasts after chondrocyte hypertrophy and cartilage matrix calcification and that the mineral concentration of calcified meckel's cartilage is comparable to that of the surrounding bone. 2022-02-05 2022-01-13 Not clear
Mapula Razwinani, Keolebogile Shirley Motaun. The influence of friedelin, resinone, tingenone and betulin of compounds on chondrogenic differentiation of porcine adipose-derived mesenchymal stem cells (pADMSCs). Biochimie vol issue 2022 35121053 the study investigated the influence of friedelin, resinone, tingenone and betulin plant-based secondary metabolite compounds on cellular proliferation, extracellular matrix (ecm) components synthesis, expression of chondrogenic markers and maturation of differentiated chondrocytes (cell proliferation and hypertrophy) in porcine adipose-derived mesenchymal stem cells (padmscs) undergoing chondrogenic differentiation. 2022-02-05 2022-02-06 Not clear
Jianlin Feng, Maria K Armillei, Albert S Yu, Bruce T Liang, Loren W Runnels, Lixia Yu. Ca Journal of cardiovascular development and disease vol 6 issue 4 2021 31547577 ca cardiac fibrosis is the excessive deposition of extracellular matrix proteins by cardiac fibroblasts and myofibroblasts, and is a hallmark feature of most heart diseases, including arrhythmia, hypertrophy, and heart failure. 2022-01-29 2022-01-13 Not clear
Jinying Liu, Hongjian Lian, Jiang Yu, Jie Wu, Xiangyang Chen, Peng Wang, Lei Tian, Yunfei Yang, Jiaqi Yang, Dong Li, Shuzhen Gu. Study on diverse pathological characteristics of heart failure in different stages based on proteomics. Journal of cellular and molecular medicine vol issue 2022 35048506 the results of the kegg pathway enrichment analysis and go function annotation revealed critical pathways associated with the transition from cardiac hypertrophy to heart failure, such as energy pathways and matrix reorganization. 2022-01-20 2022-01-27 Not clear
Ying Zhang, Zhengzheng Li, Ying He, Meng Zhang, Yiping Feng, Qian Fang, Tianyou Ma, Xianghua Deng, Jinghong Che. Transforming growth factor-\\xce\\xb2 receptors mediates matrix degradation and abnormal hypertrophy in T-2 toxin-induced hypertrophic chondrocytes. Toxicon : official journal of the International Society on Toxinology vol issue 2022 34995556 transforming growth factor-\xce\xb2 receptors mediates matrix degradation and abnormal hypertrophy in t-2 toxin-induced hypertrophic chondrocytes. 2022-01-07 2022-01-13 Not clear
Ying Zhang, Zhengzheng Li, Ying He, Meng Zhang, Yiping Feng, Qian Fang, Tianyou Ma, Xianghua Deng, Jinghong Che. Transforming growth factor-\\xce\\xb2 receptors mediates matrix degradation and abnormal hypertrophy in T-2 toxin-induced hypertrophic chondrocytes. Toxicon : official journal of the International Society on Toxinology vol issue 2022 34995556 this study investigated whether transforming growth factor-\xce\xb2 receptor i (tgf-\xce\xb2ri) and tgf-\xce\xb2rii mediate matrix degradation and abnormal hypertrophy in t-2 toxin-induced hypertrophic chondrocytes. 2022-01-07 2022-01-13 Not clear
Ying Zhang, Zhengzheng Li, Ying He, Meng Zhang, Yiping Feng, Qian Fang, Tianyou Ma, Xianghua Deng, Jinghong Che. Transforming growth factor-\\xce\\xb2 receptors mediates matrix degradation and abnormal hypertrophy in T-2 toxin-induced hypertrophic chondrocytes. Toxicon : official journal of the International Society on Toxinology vol issue 2022 34995556 the upregulated expression of tgf-\xce\xb2ri and tgf-\xce\xb2rii mediates the abnormal chondrocyte hypertrophy and extracellular matrix degeneration observed in t-2 toxin-induced hypertrophic chondrocytes. 2022-01-07 2022-01-13 Not clear
Maria Marketou, Joanna Kontaraki, Spyros Maragkoudakis, Christos Danelatos, Sofia Papadaki, Stelios Zervakis, Anthoula Plevritaki, Panos Vardas, Fragiskos Parthenakis, George Kochiadaki. Effects of sodium-glucose cotransporter-2 inhibitors on cardiac structural and electrical remodeling: from myocardial cytology to cardiodiabetology. Current vascular pharmacology vol issue 2021 34961447 sglt2i ameliorate myocardial extracellular matrix remodeling, cardiomyocyte stiffness and concentric hypertrophy, achieving beneficial remodeling of the left ventricle with significant implications for the pathogenesis and outcome of heart failure. 2021-12-28 2022-01-13 Not clear
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