All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Yvonne Peck, Ling Yen Ng, Jie Yi Lois Goh, Changyou Gao, Dong-An Wan. A three-dimensionally engineered biomimetic cartilaginous tissue model for osteoarthritic drug evaluation. Molecular pharmaceutics. vol 11. issue 7. 2016-05-04. PMID:24579704. up-regulation of matrix metalloproteinase-1 (mmp-1) and mmp-3 genes suggested increased degradative activity, while chondrocytic hypertrophic differentiation was observed. 2016-05-04 2023-08-12 Not clear
Stacey C Skaalure, Stanley Chu, Stephanie J Bryan. An enzyme-sensitive PEG hydrogel based on aggrecan catabolism for cartilage tissue engineering. Advanced healthcare materials. vol 4. issue 3. 2016-05-03. PMID:25296398. in contrast, matrix deposition in the nondegradable hydrogels consists of aggrecan and collagens i, ii, and x, indicative of hypertrophic cartilage. 2016-05-03 2023-08-13 cattle
Shuang Yang, Sumita Mishra, Lijun Chen, Jian-Ying Zhou, Daniel W Chan, Subroto Chatterjee, Hui Zhan. Integrated glycoprotein immobilization method for glycopeptide and glycan analysis of cardiac hypertrophy. Analytical chemistry. vol 87. issue 19. 2016-05-02. PMID:26378618. we identified 291 unique glycopeptides from 195 glycoproteins; the comparative studies between wt and tac mice indicate the overexpression of extracellular proteins for heart matrix remodeling and the down-regulation of proteins associated with energy metabolism in cardiac hypertrophy. 2016-05-02 2023-08-13 mouse
T Akisaka, C V Ga. The plasma membrane and matrix vesicles of mouse growth plate chondrocytes during differentiation as revealed in freeze-fracture replicas. The American journal of anatomy. vol 173. issue 4. 2016-04-23. PMID:20726124. imp-aggregated and imp-free matrix vesicles became increasingly frequent in the later stages of differentiation, particularly in the late hypertrophic stage. 2016-04-23 2023-08-12 mouse
Xiaozhi Bai, Ting He, Jiaqi Liu, Yunchuan Wang, Lei Fan, Ke Tao, Jihong Shi, Chaowu Tang, Linlin Su, Dahai H. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Experimental dermatology. vol 24. issue 5. 2016-04-22. PMID:25683490. loureirin b inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via tgf-β/smad pathway. 2016-04-22 2023-08-13 human
Mario Notari, Julián Pulecio, Ángel Ray. Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease. BioMed research international. vol 2015. 2016-04-21. PMID:26221581. for instance, acute myocardial infarction induces cardiac tissue necrosis and apoptosis but also initiates a pathological remodelling response of the left ventricle that includes hypertrophic growth of cardiomyocytes and fibrotic deposition of extracellular matrix components. 2016-04-21 2023-08-13 Not clear
Chia-Li M Shih, Kolapo M Ajuwo. Inhibition of MMP-13 prevents diet-induced obesity in mice and suppresses adipogenesis in 3T3-L1 preadipocytes. Molecular biology reports. vol 42. issue 7. 2016-03-10. PMID:25682268. adipose tissue remodeling by the matrix metalloproteases (mmps) is critical for tissue hypertrophy and obesity. 2016-03-10 2023-08-13 mouse
Jing-Jing Yang, Yan-ru Huang, Yi-gang Wan, Shan-mei Shen, Zhi-min Mao, Wei Wu, Jian Ya. [Regulative mechanisms of mammalian target of rapamycin signaling pathway in glomerular hypertrophy in diabetic nephropathy and interventional effects of Chinese herbal medicine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 16. 2016-03-10. PMID:26790279. rapamycin, the inhibitor of mtor, could suppress glomerular inherent cell hypertrophy, cell proliferation, glomerular basement membrane (gbm) thickening and mesangial matrix deposition in model rats with dn. 2016-03-10 2023-08-13 rat
Wei-Jian Ni, Hai-Hua Ding, Li-Qin Tan. Berberine as a promising anti-diabetic nephropathy drug: An analysis of its effects and mechanisms. European journal of pharmacology. vol 760. 2016-03-08. PMID:25912800. diabetic nephropathy is a progressive kidney disorder and is pathologically characterized by thickened glomerular and tubular basement membranes, accumulation of the extracellular matrix and increased mesangial hypertrophy. 2016-03-08 2023-08-13 Not clear
Koichi Matsuo, Yukiko Kuroda, Nobuhito Nango, Kouji Shimoda, Yoshiaki Kubota, Masatsugu Ema, Latifa Bakiri, Erwin F Wagner, Yoshihiro Takeda, Wataru Yashiro, Atsushi Momos. Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus. Development (Cambridge, England). vol 142. issue 22. 2016-03-04. PMID:26428006. terminally differentiated hypertrophic chondrocytes are calcified, vascularized, and removed by chondroclasts before bone matrix is laid down by osteoblasts. 2016-03-04 2023-08-13 mouse
Hirohisa Kawahata, Daisuke Sotobayashi, Motokuni Aoki, Hideo Shimizu, Hironori Nakagami, Toshio Ogihara, Ryuichi Morishit. Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse. Hypertension research : official journal of the Japanese Society of Hypertension. vol 38. issue 6. 2016-03-03. PMID:25693858. it was also confirmed by a significant increase in the mrna expression of sox9 and runt-related transcription factor 2 (runx2), which are genes related to chondrocyte differentiation, and type x collagen, matrix metalloproteinase (mmp)-13 and indian hedgehog (ihh), which are hypertrophic chondrocyte-specific molecular markers. 2016-03-03 2023-08-13 mouse
Jianquan Chen, Nilsson Holguin, Yu Shi, Matthew J Silva, Fanxin Lon. mTORC2 signaling promotes skeletal growth and bone formation in mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 30. issue 2. 2016-02-22. PMID:25196701. subsequently, the embryonic skeletal elements are shortened due to a delay in chondrocyte hypertrophy, with no change in proliferation, apoptosis, cell size, or matrix production. 2016-02-22 2023-08-13 mouse
Nirmalya Dey, Amit Bera, Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S Kasinath, Goutam Ghosh Choudhur. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression. Cellular signalling. vol 27. issue 7. 2016-02-16. PMID:25797045. high glucose enhances microrna-26a to activate mtorc1 for mesangial cell hypertrophy and matrix protein expression. 2016-02-16 2023-08-13 Not clear
Nirmalya Dey, Amit Bera, Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S Kasinath, Goutam Ghosh Choudhur. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression. Cellular signalling. vol 27. issue 7. 2016-02-16. PMID:25797045. high glucose milieu inhibits pten expression to activate akt kinase and induces glomerular mesangial cell hypertrophy and matrix protein expression in diabetic nephropathy. 2016-02-16 2023-08-13 Not clear
Nirmalya Dey, Amit Bera, Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S Kasinath, Goutam Ghosh Choudhur. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression. Cellular signalling. vol 27. issue 7. 2016-02-16. PMID:25797045. akt-mediated phosphorylation of tuberin and pras40 regulates mtorc1, which is necessary for mesangial cell hypertrophy and matrix protein expression. 2016-02-16 2023-08-13 Not clear
Nirmalya Dey, Amit Bera, Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S Kasinath, Goutam Ghosh Choudhur. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression. Cellular signalling. vol 27. issue 7. 2016-02-16. PMID:25797045. together our results provide the first evidence for the involvement of mir-26a in high glucose-induced mesangial cell hypertrophy and matrix protein expression. 2016-02-16 2023-08-13 Not clear
Ilja L Krugliko. Microstructural inhomogeneity of electrical conductivity in subcutaneous fat tissue. PloS one. vol 10. issue 3. 2016-01-27. PMID:25734656. this effect is connected with different electrical conductivities of pathways inside (triglycerides in adipocytes) and outside (extra-cellular matrix) the cells and to the different weighting of these pathways in hypertrophic and hyperplastic types of swat. 2016-01-27 2023-08-13 Not clear
Ilja L Krugliko. Microstructural inhomogeneity of electrical conductivity in subcutaneous fat tissue. PloS one. vol 10. issue 3. 2016-01-27. PMID:25734656. the application of the rf current to hypertrophic swat, which normally has a strongly developed extracellular matrix with high concentrations of hyaluronan and collagen in a peri-cellular space of adipocytes, can produce, micro-structurally, a highly inhomogeneous temperature distribution, characterized by strong temperature gradients between the peri-cellular sheath of the extra-cellular matrix around the hypertrophic adipocytes and their volumes. 2016-01-27 2023-08-13 Not clear
Jenny Y Y Ooi, Natasha K Tuano, Haloom Rafehi, Xiao-Ming Gao, Mark Ziemann, Xiao-Jun Du, Assam El-Ost. HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes. Epigenetics. vol 10. issue 5. 2016-01-25. PMID:25941940. pressure overload-induced cardiac hypertrophy was associated with histone acetylation of genes implicated in cardiac contraction, collagen deposition, inflammation, and extracellular matrix identified by chip-seq. 2016-01-25 2023-08-13 human
Amaia Rodríguez, Silvia Ezquerro, Leire Méndez-Giménez, Sara Becerril, Gema Frühbec. Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism. American journal of physiology. Endocrinology and metabolism. vol 309. issue 8. 2016-01-25. PMID:26330344. the mechanisms underlying the development of obesity and its associated comorbidities include the hypertrophy and/or hyperplasia of adipocytes, adipose tissue inflammation, impaired extracellular matrix remodeling, and fibrosis together with an altered secretion of adipokines. 2016-01-25 2023-08-13 Not clear