All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Minghao Qu, Mingjue Chen, Weiyuan Gong, Shaochuan Huo, Qinnan Yan, Qing Yao, Yumei Lai, Di Chen, Xiaohao Wu, Guozhi Xia. Pip5k1c Loss in Chondrocytes Causes Spontaneous Osteoarthritic Lesions in Aged Mice. Aging and disease. vol 14. issue 2. 2023-04-03. PMID:37008048. pip5k1c loss promotes extracellular matrix (ecm) degradation, chondrocyte hypertrophy and apoptosis, and inhibits chondrocyte proliferation in the articular cartilage of aged mice. 2023-04-03 2023-08-14 mouse
Qian Yu, Qiang Dai, Zonglin Huang, Chen Li, Li Yan, Xin Fu, Qian Wang, Yi Zhang, Lei Cai, Zhigang Yang, Ran Xia. Microfat exerts an anti-fibrotic effect on human hypertrophic scar via fetuin-A/ETV4 axis. Journal of translational medicine. vol 21. issue 1. 2023-04-02. PMID:37004048. hypertrophic scar is a fibrotic disease following wound healing and is characterized by excessive extracellular matrix deposition. 2023-04-02 2023-08-14 human
Manjula P Mony, Kelly A Harmon, Ryan Hess, Amir H Dorafshar, Sasha H Shafikhan. An Updated Review of Hypertrophic Scarring. Cells. vol 12. issue 5. 2023-03-11. PMID:36899815. hypertrophic scarring (hts) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. 2023-03-11 2023-08-14 Not clear
Shenyi Jiang, Shuhao Qian, Lingxi Zhou, Jia Meng, Rushan Jiang, Chuncheng Wang, Xinguo Fang, Chen Yang, Zhihua Ding, Shuangmu Zhuo, Zhiyi Li. Mapping the 3D remodeling of the extracellular matrix in human hypertrophic scar by multi-parametric multiphoton imaging using endogenous contrast. Heliyon. vol 9. issue 2. 2023-03-06. PMID:36873151. mapping the 3d remodeling of the extracellular matrix in human hypertrophic scar by multi-parametric multiphoton imaging using endogenous contrast. 2023-03-06 2023-08-14 human
Irina V Kologrivova, Natalia V Naryzhnaya, Olga A Koshelskaya, Tatiana E Suslova, Elena S Kravchenko, Olga A Kharitonova, Vladimir V Evtushenko, Alla A Boshchenk. Association of Epicardial Adipose Tissue Adipocytes Hypertrophy with Biomarkers of Low-Grade Inflammation and Extracellular Matrix Remodeling in Patients with Coronary Artery Disease. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36830779. association of epicardial adipose tissue adipocytes hypertrophy with biomarkers of low-grade inflammation and extracellular matrix remodeling in patients with coronary artery disease. 2023-02-25 2023-08-14 Not clear
Lei Huang, Meng Jin, Ruiying Gu, Kunlin Xiao, Mengnan Lu, Xinyu Huo, Mengyao Sun, Zhi Yang, Zhiyuan Wang, Weijie Zhang, Liqiang Zhi, Ziang Meng, Jie Ma, Jianbing Ma, Rui Zhan. miR-199a-5p Reduces Chondrocyte Hypertrophy and Attenuates Osteoarthritis Progression via the Indian Hedgehog Signal Pathway. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835852. further investigations demonstrated that mir-199a-5p could directly regulate ihh expression and reduce chondrocyte hypertrophy and matrix degradation via the ihh signal pathway in the primary human chondrocytes. 2023-02-25 2023-08-14 human
Chin-Chan Lee, Chia-Chun Chen, Cheng-Kai Hsu, Yih-Ting Chen, Chun-Yu Chen, Kai-Jie Yang, Ming-Jui Hung, I-Wen W. Urinary microRNA in Diabetic Kidney Disease: A Literature Review. Medicina (Kaunas, Lithuania). vol 59. issue 2. 2023-02-25. PMID:36837555. previous literatures have reported its potential role in the pathophysiology of diabetic kidney disease, including regulation of transforming growth factor-β1-mediated fibrosis, extracellular matrix and cell adhesion proteins, cellular hypertrophy, growth factor, cytokine production, and redox system activation. 2023-02-25 2023-08-14 Not clear
Joshua S Godwin, Casey L Sexton, Nicholas J Kontos, Bradley A Ruple, Darryn S Willoughby, Kaelin C Young, C Brooks Mobley, Michael D Robert. Extracellular matrix content and remodeling markers do not differ in college-aged men classified as higher- and lower-responders to resistance training. Journal of applied physiology (Bethesda, Md. : 1985). 2023-02-09. PMID:36759158. we determined if skeletal muscle extracellular matrix (ecm) content and remodeling markers adapted with resistance training or were associated with hypertrophic outcomes. 2023-02-09 2023-08-14 human
Charly Robert, Frédéric Kerff, Fabrice Bouillenne, Maxime Gavage, Marylène Vandevenne, Patrice Filée, André Matagn. Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. The Journal of biological chemistry. 2023-01-15. PMID:36642181. additionally, several in vitro cell-based assays, including enzymatic measurements, rt-qpcr and matrix staining, demonstrated their biological activity during cell chondrogenic and hypertrophic differentiation. 2023-01-15 2023-08-14 human
Guoqing Li, Su Liu, Huihui Xu, Yixiao Chen, Jiapeng Deng, Ao Xiong, Deli Wang, Jian Weng, Fei Yu, Liang Gao, Changhai Ding, Hui Zen. Potential effects of teriparatide (PTH (1-34)) on osteoarthritis: a systematic review. Arthritis research & therapy. vol 25. issue 1. 2023-01-07. PMID:36609338. in vitro studies (n = 11) concluded that pth (1-34) was important for chondrocytes via increasing the proliferation and matrix synthesis but preventing apoptosis or hypertrophy. 2023-01-07 2023-08-14 Not clear
James T Pearso. Set7 methyltransferase roles in myocardial protection from chronic stressors. Clinical science (London, England : 1979). vol 137. issue 1. 2023-01-05. PMID:36601782. recent transcriptome and fourier transform infrared spectroscopy analyses and in vivo assessments of cardiac function by lunardon and colleagues now reveal a clear role of set7 in the regulation of the extracellular matrix composition and cardiac hypertrophy in response to chronic isoproterenol induced cardiac stress. 2023-01-05 2023-08-14 Not clear
Helena M Viola, Caitlyn Richworth, Tanya Solomon, Ian L Chin, Henrietta Cserne Szappanos, Srinivasan Sundararaj, Dmitry Shishmarev, Marco G Casarotto, Yu Suk Choi, Livia C Hoo. A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. Communications biology. vol 6. issue 1. 2023-01-03. PMID:36596888. a maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. 2023-01-03 2023-08-14 human
Helena M Viola, Caitlyn Richworth, Tanya Solomon, Ian L Chin, Henrietta Cserne Szappanos, Srinivasan Sundararaj, Dmitry Shishmarev, Marco G Casarotto, Yu Suk Choi, Livia C Hoo. A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. Communications biology. vol 6. issue 1. 2023-01-03. PMID:36596888. we identify a mechanosensing feedback mechanism between the extracellular matrix and cytoskeletal network that regulates mitochondrial function under healthy conditions, but participates in the progression of hypertrophic cardiomyopathy pathophysiology resulting from sarcomeric gene mutations. 2023-01-03 2023-08-14 human
Hubert Kol. Obese visceral fat tissue inflammation: from protective to detrimental? BMC medicine. vol 20. issue 1. 2022-12-27. PMID:36575472. eventual lipid overload of hypertrophic adipocytes leads to endoplasmic reticulum stress and the secretion of a variety of signals causing increased sympathetic tone, lipolysis by adipocytes, lipid uptake by macrophages, matrix remodeling, angiogenesis, and immune cell activation. 2022-12-27 2023-08-14 Not clear
Shikha Chawla, Andrea Mainardi, Nilotpal Majumder, Laura Dönges, Bhupendra Kumar, Paola Occhetta, Ivan Martin, Christian Egloff, Sourabh Ghosh, Amitabha Bandyopadhyay, Andrea Barber. Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies. Cells. vol 11. issue 24. 2022-12-23. PMID:36552796. afterwards, we will present the strategies developed and proposed to impede chondrocyte hypertrophy and cartilage matrix mineralization/calcification. 2022-12-23 2023-08-14 Not clear
Zhencheng Yu, Yun Li, Rao Fu, Yaxin Xue, Danyang Zhao, Dong Ha. Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway. Archives of dermatological research. 2022-12-16. PMID:36526799. abnormal fibroblast proliferation and excessive extracellular matrix (ecm) deposition lead to the formation of hypertrophic scars (hss). 2022-12-16 2023-08-14 human
Ashley A Thurstin, Allison N Egeli, Edie C Goldsmith, Francis G Spinale, Holly A LaVoi. Tissue Inhibitor of Metalloproteinase 4 (Timp4) Deletion in Mice Impacts Maternal Cardiac Function during Pregnancy and Postpartum. American journal of physiology. Heart and circulatory physiology. 2022-12-02. PMID:36459450. reversible physiological cardiac hypertrophy of the maternal heart occurs during pregnancy and involves extracellular matrix (ecm) remodeling. 2022-12-02 2023-08-14 mouse
Cassandra L Clift, Janet Saunders, Richard R Drake, Peggi M Ange. Perspectives on pediatric congenital aortic valve stenosis: Extracellular matrix proteins, post translational modifications, and proteomic strategies. Frontiers in cardiovascular medicine. vol 9. 2022-11-28. PMID:36439995. this is especially true in cases of pediatric congenital aortic valve stenosis (pcavs), in which extracellular matrix (ecm) dysregulation is a hallmark of the disease, eventually leading to left ventricular hypertrophy and heart failure. 2022-11-28 2023-08-14 Not clear
Yan Yang, Lutong Liu, Xiaojin Wu, Xue Wang, Qiang Lu, Zhen Zhan. CO Burns & trauma. vol 10. 2022-11-16. PMID:36380852. co hypertrophic scars are skin fibrotic diseases, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. 2022-11-16 2023-08-14 Not clear
Farideh Amirrad, Gregory A Fishbein, Robert A Edwards, Surya M Naul. Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-β Cell and tissue research. 2022-11-15. PMID:36376769. our histopathology data of human pkd hearts showed an increased extracellular matrix associated with cardiac hypertrophy and fibrosis. 2022-11-15 2023-08-14 human