All Relations between local circuit neuron and orbital frontal cortex
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Rebecca L Openshaw, David M Thomson, Greg C Bristow, Emma J Mitchell, Judith A Pratt, Brian J Morris, Neil Dawso. 16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability. Communications biology. vol 6. issue 1. 2023-05-24. PMID:37225770. |
here we show that mice reproducing this deletion (16p11.2 del mice) have reduced gabaergic interneuron gene expression (decreased parvalbumin mrna in orbitofrontal cortex, and male-specific decreases in gad67 mrna in parietal and insular cortex and medial septum). |
2023-05-24 |
2023-08-14 |
mouse |
Katherine J Robinson, Nicholas A Everett, Sarah J Baracz, Jennifer L Cornis. The effect of self-administered methamphetamine on GABAergic interneuron populations and functional connectivity of the nucleus accumbens and prefrontal cortex. Psychopharmacology. 2022-08-03. PMID:35920922. |
here we investigate meth-induced changes to neuronal nitric oxide synthase (nnos), parvalbumin and calretinin-expressing gabaergic interneuron populations within the nucleus accumbens (nac), prefrontal cortex (pfc) and orbitofrontal cortex (ofc). |
2022-08-03 |
2023-08-14 |
Not clear |
Haley L Goodwill, Gabriela Manzano-Nieves, Patrick LaChance, Sana Teramoto, Shirley Lin, Chelsea Lopez, Rachel J Stevenson, Brian B Theyel, Christopher I Moore, Barry W Connors, Kevin G Bat. Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice. Cell reports. vol 25. issue 9. 2019-12-11. PMID:30485800. |
impaired performance was associated with decreased expression and density of interneurons expressing parvalbumin (pv+) in orbitofrontal cortex (ofc), but not other interneuron subtypes. |
2019-12-11 |
2023-08-13 |
mouse |