Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Janna B Hart, Robert K Poon, Robert E Ward, Korry J Hintze, Sara M Freema. Effects of Dietary Fiber on Short Chain Fatty Acid Receptor mRNA in Microglia and Serotonergic Neurons in the Mouse Brain. Neuroscience. 2024-03-02. PMID:38431042. |
we found high colocalization of scfa receptors in both microglia and serotonergic neurons and discovered that scfa receptor expression in the dorsal raphe is driven by fiber solubility, while scfa receptor expression in the hippocampus is driven by fiber amount. |
2024-03-02 |
2024-03-06 |
mouse |
Kanza M Khan, Gabrielle Bierlein-De La Rosa, Natalie Biggerstaff, Govindhasamy Pushpavathi Selvakumar, Ruixiang Wang, Suzanne Mason, Michael E Dailey, Catherine A Marcinkiewc. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain, behavior, and immunity. 2022-07-30. PMID:35907582. |
here we report that mice exposed to adolescent intermittent access to ethanol (aie) exhibit increased pain sensitivity and depressive-like behaviors that persist for several weeks after alcohol cessation and are accompanied by elevated cd68 expression in microglia and reduced numbers of serotonin (5-ht)-expressing neurons in the dorsal raphe nucleus (drn). |
2022-07-30 |
2023-08-14 |
mouse |
Shannon Hall, Samüel Deurveilher, George S Robertson, Kazue Semb. Homeostatic state of microglia in a rat model of chronic sleep restriction. Sleep. vol 43. issue 11. 2021-04-14. PMID:32474610. |
after 27 and/or 99 h of csr, the number of cells immunoreactive for the microglia marker ionized calcium-binding adaptor molecule-1 (iba1) and the density of iba1 immunoreactivity were increased in 4/10 brain regions involved in sleep/wake regulation and cognition, including the prelimbic cortex, central amygdala, perifornical lateral hypothalamic area, and dorsal raphe nucleus. |
2021-04-14 |
2023-08-13 |
rat |
Ralf Brisch, Johann Steiner, Christian Mawrin, Marta Krzyżanowska, Zbigniew Jankowski, Tomasz Go. Microglia in the dorsal raphe nucleus plays a potential role in both suicide facilitation and prevention in affective disorders. European archives of psychiatry and clinical neuroscience. vol 267. issue 5. 2018-01-30. PMID:28229240. |
microglia in the dorsal raphe nucleus plays a potential role in both suicide facilitation and prevention in affective disorders. |
2018-01-30 |
2023-08-13 |
Not clear |
Ralf Brisch, Johann Steiner, Christian Mawrin, Marta Krzyżanowska, Zbigniew Jankowski, Tomasz Go. Microglia in the dorsal raphe nucleus plays a potential role in both suicide facilitation and prevention in affective disorders. European archives of psychiatry and clinical neuroscience. vol 267. issue 5. 2018-01-30. PMID:28229240. |
the dorsal raphe nucleus (drn) is the main source of serotonergic innervation of forebrain limbic structures disturbed in suicidal behaviour, in which an abnormal microglia reaction seems to play a role. |
2018-01-30 |
2023-08-13 |
Not clear |
Joshua L Cohen, Anooshah E Ata, Nateka L Jackson, Elizabeth J Rahn, Ryne C Ramaker, Sara Cooper, Ilan A Kerman, Sarah M Clinto. Differential stress induced c-Fos expression and identification of region-specific miRNA-mRNA networks in the dorsal raphe and amygdala of high-responder/low-responder rats. Behavioural brain research. vol 319. 2017-12-21. PMID:27865919. |
a dorsal raphe network linked three micrornas which were down-regulated in lrs (mir-206-3p, mir-3559-5p, and mir-378a-3p) to repression of genes related to microglia and immune response (cd74, cyth4, nckap1l, and rac2), the genes themselves were up-regulated in lr dorsal raphe. |
2017-12-21 |
2023-08-13 |
rat |