All Relations between microglial cell and hippocampus

Reference Sentence Publish Date Extraction Date Species
Jie Luo, Jing-Qiong Wang, Li-Na Xie, An-Na Meng, Si-Si Zheng, Shou-Hong Zho. [Voluntary wheel running exercise regulates microglia polarization in hippocampus through STAT3 signal pathway to inhibit depression-like behavior induced by chronic stress in rats]. Sheng li xue bao : [Acta physiologica Sinica] vol 74 issue 2 2022 35503065 these results suggest that voluntary wheel running ameliorates the depression-like behavior induced by cwirs in rats, and the mechanism may be related to regulating hippocampal microglia polarization via stat3 signaling pathway. 2022-05-03 2022-05-06 Not clear
Li Lu, Xuan Liu, Juanhua Fu, Jun Liang, Yayi Hou, Huan Do. sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K-AKT signaling pathway. Scientific reports vol 12 issue 1 2022 35487953 after intracerebroventricular (icv) injection, the damage in hippocampal neurons increased, and the loss of neuronal synapses and activation of microglia increased compared to the control mice (treated with saline). 2022-04-29 2022-05-03 Not clear
Yu Ren, Qing Wang, Zexian Yang, Linyin Feng, Yu Zhan. MCC950 ameliorates the dementia symptom at the early age of line M83 mouse and reduces hippocampal \\xce\\xb1-synuclein accumulation. Biochemical and biophysical research communications vol 611 issue 2022 35472607 furthermore, immunostaining or immunoblotting experiments on the hippocampal tissue were performed, and the results suggested that mcc950 not only inhibited the expression of nlrp3, and suppressed the activation of astrocytes and microglia, but also promoted the mtor-mediated autophagy pathway to reduce human \xce\xb1-synuclein accumulation. 2022-04-26 2022-04-30 Not clear
Woo-Ju Song, Jeongtae Kim, Taekyun Shin, Myeong-Seon Jeong, Kil-Nam Kim, Jang-Hyuk Yun, Myung-Bok Wi. Esculetin and Fucoidan Attenuate Autophagy and Apoptosis Induced by Zinc Oxide Nanoparticles through Modulating Reactive Astrocyte and Proinflammatory Cytokines in the Rat Brain. Toxics vol 10 issue 4 2022 35448455 serum and brain homogenates were examined by enzyme-linked immunosorbent assay (elisa), and neurons, microglia, and astrocytes in the hippocampal region were examined with immunohistochemical analysis. 2022-04-21 2022-04-25 Not clear
Yixing Du, Faith H Brennan, Phillip G Popovich, Min Zho. Microglia maintain the normal structure and function of the hippocampal astrocyte network. Glia vol issue 2022 35394085 microglia maintain the normal structure and function of the hippocampal astrocyte network. 2022-04-08 2022-04-14 Not clear
Jada L-B Davis, Mara O'Connor, Hannah Erlbacher, Sarah L Schlichte, Hanna E Steven. The Impact of Maternal Antioxidants on Prenatal Stress Effects on Offspring Neurobiology and Behavior. The Yale journal of biology and medicine vol 95 issue 1 2022 35370489 cell types in the brain sensitive to oxidative stress-cortical microglia and cortical and hippocampal interneurons-may be altered by oxidative stress generated during prenatal stress and may be neurobiological substrates for altered behavior. 2022-04-04 2022-04-14 Not clear
Xiaomi Ding, Jing Zhou, Li Zhao, Mingyue Chen, Shenglin Wang, Ming Zhang, Xiaodong Zhang, Guohui Jian. Intestinal Flora Composition Determines Microglia Activation and Improves Epileptic Episode Progress. Frontiers in cellular and infection microbiology vol 12 issue 2022 35356535 the seizure grade, duration, latency, hippocampal potential, and energy density were used to evaluate seizures, and the changes in the polarization of microglia were detected by western blot. 2022-03-31 2022-04-14 Not clear
Julio David Vega-Torres, Perla Ontiveros-Angel, Esmeralda Terrones, Erwin C Stuffle, Sara Solak, Emma Tyner, Marie Oropeza, Ike Dela Pe\\xc3\\xb1a, Andre Obenaus, Byron D Ford, Johnny D Figuero. Short-term exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1. Translational psychiatry vol 12 issue 1 2022 35220393 nrg1 administration reduced psd-95 protein expression (30%) and selectively reduced hippocampal cytokine levels (il-33, gm-csf, ccl-2, ifn-\xce\xb3) while significantly impacting microglia morphology (increased span ratio and reduced circularity). 2022-03-18 2022-03-02 Not clear
Julio David Vega-Torres, Perla Ontiveros-Angel, Esmeralda Terrones, Erwin C Stuffle, Sara Solak, Emma Tyner, Marie Oropeza, Ike Dela Pe\\xc3\\xb1a, Andre Obenaus, Byron D Ford, Johnny D Figuero. Short-term exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1. Translational psychiatry vol 12 issue 1 2022 35220393 wd rats exhibited reduced right hippocampal volume (7%), altered microglia morphology (reduced density and increased lacunarity), and increased levels of cytokines implicated in neuroinflammation (il-1\xce\xb1, tnf-\xce\xb1, il-6). 2022-03-18 2022-03-02 Not clear
Sonja Fixemer, Corrado Ameli, Ga\\xc3\\xabl Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques G\\xc3\\xa9rardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-\\xce\\xb2 and \\xce\\xb1-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications vol 10 issue 1 2022 35296366 furthermore, how the nature of the hippocampal local pathological imprint is associated with microglia responses needs to be elucidated. 2022-03-17 2022-04-14 Not clear
Sonja Fixemer, Corrado Ameli, Ga\\xc3\\xabl Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques G\\xc3\\xa9rardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-\\xce\\xb2 and \\xce\\xb1-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications vol 10 issue 1 2022 35296366 to this purpose, we employed an automated pipeline for analysis of 3d confocal microscopy images to assess ca1, ca3 and dg/ca4 subfields microglia responses in post-mortem hippocampal samples from late-onset ad (n\xe2\x80\x89=\xe2\x80\x8910), dlb (n\xe2\x80\x89=\xe2\x80\x898) and age-matched control (ctl) (n\xe2\x80\x89=\xe2\x80\x8911) individuals. 2022-03-17 2022-04-14 Not clear
Pamela M Maras, Elaine K Hebda-Bauer, Megan H Hagenauer, Kathryn L Hilde, Peter Blandino, Stanley J Watson, Huda Aki. Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. Translational psychiatry vol 12 issue 1 2022 35292624 using detailed anatomical analyses, we compared hippocampal microglia profiles of bhrs and blrs and found that although the lines had similar numbers of microglia, selective breeding was associated with a shift in the morphological features of these cells. 2022-03-16 2022-04-14 Not clear
Rui Huang, Yuyuan Gao, Jianing Chen, Qingrui Duan, Peikun He, Jiahui Zhang, Heling Huang, Qingxi Zhang, Guixian Ma, Yuhu Zhang, Kun Nie, Lijuan Wan. TGR5 agonist INT-777 alleviates inflammatory neurodegeneration in parkinson's disease mouse model by modulating mitochondrial dynamics in microglia. Neuroscience vol issue 2022 35257795 therefore, pd cognitive impairment is associated with hippocampal tnf-\xce\xb1 elevation as a result of mitochondrial damage in microglia. 2022-03-14 2022-03-09 Not clear
Michael Ratz, Leonie von Berlin, Ludvig Larsson, Marcel Martin, Jakub Orzechowski Westholm, Gioele La Manno, Joakim Lundeberg, Jonas Fris\\xc3\\xa9. Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics. Nature neuroscience vol issue 2022 35210624 by reconstructing thousands of clones, we discovered fate-restricted progenitor cells in the mouse hippocampal neuroepithelium and show that microglia are derived from few primitive myeloid precursors that massively expand to generate widely dispersed progeny. 2022-03-09 2022-02-27 Not clear
Zhuo Fan, Wendi Zhang, Qi Cao, Lingyun Zou, Xiaobei Fan, Changcun Qi, Yuandong Yan, Bo Song, Bailin W. JAK2/STAT3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. Ecotoxicology and environmental safety vol 234 issue 2022 35248926 jak2/stat3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. 2022-03-08 2022-03-09 Not clear
Zhuo Fan, Wendi Zhang, Qi Cao, Lingyun Zou, Xiaobei Fan, Changcun Qi, Yuandong Yan, Bo Song, Bailin W. JAK2/STAT3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. Ecotoxicology and environmental safety vol 234 issue 2022 35248926 to explore the effects of acute paraquat (pq) exposure on the phenotypic polarization of hippocampal microglia and its mechanism. 2022-03-08 2022-03-09 Not clear
Jiamei Guo, Tian Qiu, Lixia Wang, Lei Shi, Ming Ai, Zhu Xia, Zhiping Peng, Anhai Zheng, Xiao Li, Li Kuan. Microglia Loss and Astrocyte Activation Cause Dynamic Changes in Hippocampal [ Frontiers in cellular neuroscience vol 16 issue 2022 35250485 microglia loss and astrocyte activation cause dynamic changes in hippocampal [ major depression is a serious and chronic mental illness. 2022-03-08 2022-03-09 Not clear
Rui Huang, Yuyuan Gao, Jianing Chen, Qingrui Duan, Peikun He, Jiahui Zhang, Heling Huang, Qingxi Zhang, Guixian Ma, Yuhu Zhang, Kun Nie, Lijuan Wan. TGR5 agonist INT-777 alleviates inflammatory neurodegeneration in parkinson's disease mouse model by modulating mitochondrial dynamics in microglia. Neuroscience vol issue 2022 35257795 therefore, pd cognitive impairment is associated with hippocampal tnf-\xce\xb1 elevation as a result of mitochondrial damage in microglia. 2022-03-08 2022-03-09 Not clear
Teresa Cramer, Raminder Gill, Zahra S Thirouin, Markus Vaas, Suchita Sampath, Fanny Martineau, Sara B Noya, Patrizia Panzanelli, Tania J J Sudharshan, David Colameo, Philip K-Y Chang, Pei You Wu, Roy Shi, Philip A Barker, Steven A Brown, Rosa C Paolicelli, Jan Klohs, Rebecca Anne McKinney, Shiva K Tyagaraja. Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia. Science advances vol 8 issue 9 2022 35245123 here, using in vitro organotypic hippocampal slice cultures and transient middle cerebral artery occlusion (mcao) in genetically engineered mice in vivo, we report that at 24 hours after ischemia, microglia release brain-derived neurotrophic factor (bdnf) to downregulate glutamatergic and gabaergic synapses within the peri-infarct area. 2022-03-07 2022-03-07 Not clear
Jiamei Guo, Tian Qiu, Lixia Wang, Lei Shi, Ming Ai, Zhu Xia, Zhiping Peng, Anhai Zheng, Xiao Li, Li Kuan. Microglia Loss and Astrocyte Activation Cause Dynamic Changes in Hippocampal [ Frontiers in cellular neuroscience vol 16 issue 2022 35250485 microglia loss and astrocyte activation cause dynamic changes in hippocampal [ major depression is a serious and chronic mental illness. 2022-03-07 2022-03-09 Not clear
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