| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Federica Cordella, Caterina Sanchini, Maria Rosito, Laura Ferrucci, Natalia Pediconi, Barbara Cortese, Francesca Guerrieri, Giuseppe Rubens Pascucci, Fabrizio Antonangeli, Giovanna Peruzzi, Maria Giubettini, Bernadette Basilico, Francesca Pagani, Alfonso Grimaldi, Giuseppina D'Alessandro, Cristina Limatola, Davide Ragozzino, Silvia Di Angelantoni. Antibiotics Treatment Modulates Microglia-Synapses Interaction. Cells. vol 10. issue 10. 2021-11-25. PMID:34685628. |
hippocampal microglia from adult mice treated with oral antibiotics exhibited increased microglia density, altered basal patrolling activity, and impaired process rearrangement in response to damage. |
2021-11-25 |
2023-08-13 |
mouse |
| Yi Li, Lixia DU, Xiaofeng Guo, Xijing Zhan. [Cognitive impairments relate to the expression of α7 nicotinic acetylcholinergic receptor (α7nAChR) and the proportion of M1/M2 microglia in the hippocampus of male mice with sepsis-associated encephalopathy]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 11. 2021-11-24. PMID:34809734. |
[cognitive impairments relate to the expression of α7 nicotinic acetylcholinergic receptor (α7nachr) and the proportion of m1/m2 microglia in the hippocampus of male mice with sepsis-associated encephalopathy]. |
2021-11-24 |
2023-08-13 |
mouse |
| Yi Li, Lixia DU, Xiaofeng Guo, Xijing Zhan. [Cognitive impairments relate to the expression of α7 nicotinic acetylcholinergic receptor (α7nAChR) and the proportion of M1/M2 microglia in the hippocampus of male mice with sepsis-associated encephalopathy]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 11. 2021-11-24. PMID:34809734. |
the expression and distribution of α7 nicotinic acetylcholinergic receptor (α7nachr) and the proportion of m2 microglia in hippocampus of sae mice were detected by immunofluorescence staining, and the level of α7nachr protein was detected by western blot. |
2021-11-24 |
2023-08-13 |
mouse |
| Yi Li, Lixia DU, Xiaofeng Guo, Xijing Zhan. [Cognitive impairments relate to the expression of α7 nicotinic acetylcholinergic receptor (α7nAChR) and the proportion of M1/M2 microglia in the hippocampus of male mice with sepsis-associated encephalopathy]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 11. 2021-11-24. PMID:34809734. |
conclusion the expression level of α7nachr protein in hippocampus of sae male mice is significantly lower than that of sae female mice, and the proportion of m2 microglia is relatively lower, which lead to the cognitive dysfunction of sae male mice. |
2021-11-24 |
2023-08-13 |
mouse |
| Min Li, Junwen Hu, Yucong Peng, Jingbo Li, Reng Re. CircPTK2-miR-181c-5p-HMGB1: a new regulatory pathway for microglia activation and hippocampal neuronal apoptosis induced by sepsis. Molecular medicine (Cambridge, Mass.). vol 27. issue 1. 2021-11-23. PMID:33952191. |
circptk2-mir-181c-5p-hmgb1: a new regulatory pathway for microglia activation and hippocampal neuronal apoptosis induced by sepsis. |
2021-11-23 |
2023-08-13 |
mouse |
| Yun-Tao Zhao, Lulu Zhang, Haowen Yin, Ling Shen, Wenjing Zheng, Kun Zhang, Jian Zeng, Chuanyin Hu, You Li. Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling to improve stress-induced depressive behaviors in mice. Food & function. vol 12. issue 12. 2021-11-23. PMID:33998633. |
ht administration significantly suppressed microglia activation and inhibited the expression of tumor necrosis factor alpha and interleukin 1 beta in the hippocampus versus the untreated group. |
2021-11-23 |
2023-08-13 |
mouse |
| Amy C Reichelt, Claire A Lemieux, Oren Princz-Lebel, Ashmita Singh, Timothy J Bussey, Lisa M Saksid. Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33692414. |
age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption. |
2021-11-22 |
2023-08-13 |
mouse |
| Amy C Reichelt, Claire A Lemieux, Oren Princz-Lebel, Ashmita Singh, Timothy J Bussey, Lisa M Saksid. Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33692414. |
hfhs diet increased microgliosis in the adult cohort, and morphological changes to microglia were observed in the pfc and hippocampus of the adolescent cohort, with a shift to activated microglia phenotypes. |
2021-11-22 |
2023-08-13 |
mouse |
| Samuel B R Harley, Emily F Willis, Samreen N Shaikh, Daniel G Blackmore, Pankaj Sah, Marc J Ruitenberg, Perry F Bartlett, Jana Vukovi. Selective Ablation of BDNF from Microglia Reveals Novel Roles in Self-Renewal and Hippocampal Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 19. 2021-11-22. PMID:33785644. |
selective ablation of bdnf from microglia reveals novel roles in self-renewal and hippocampal neurogenesis. |
2021-11-22 |
2023-08-13 |
Not clear |
| Judith Leyh, Karsten Winter, Madlen Reinicke, Uta Ceglarek, Ingo Bechmann, Julia Landman. Long-term diet-induced obesity does not lead to learning and memory impairment in adult mice. PloS one. vol 16. issue 9. 2021-11-22. PMID:34587222. |
neurons and microglia were histologically analyzed within the mediobasal hypothalamus, hippocampus and frontal motor cortex after long-term hfd and change of diet. |
2021-11-22 |
2023-08-13 |
mouse |
| Marta Celorrio, Miguel A Abellanas, James Rhodes, Victoria Goodwin, Jennie Moritz, Sangeetha Vadivelu, Leran Wang, Rachel Rodgers, Sophia Xiao, Ilakkia Anabayan, Camryn Payne, Alexandra M Perry, Megan T Baldridge, Maria S Aymerich, Ashley Steed, Stuart H Fries. Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33691793. |
antibiotic-induced gut microbial dysbiosis established prior to tbi significantly worsened neuronal loss and reduced microglia activation in the injured hippocampus with concomitant changes in fear memory response. |
2021-11-18 |
2023-08-13 |
Not clear |
| Hongzhi Chen, Haichao Chu, Qian Jiang, Cong Wang, Yue Tia. Irf6 participates in sevoflurane-induced perioperative neurocognitive disorder via modulating M2, but not M1 polarization of microglia. Brain research bulletin. vol 177. 2021-11-18. PMID:34536519. |
perioperative neurocognitive disorder (pnd) frequently occurs in elderly patients following anesthesia, and is associated with pro-inflammatory activation of microglia in hippocampus. |
2021-11-18 |
2023-08-13 |
rat |
| Hongzhi Chen, Haichao Chu, Qian Jiang, Cong Wang, Yue Tia. Irf6 participates in sevoflurane-induced perioperative neurocognitive disorder via modulating M2, but not M1 polarization of microglia. Brain research bulletin. vol 177. 2021-11-18. PMID:34536519. |
microglia preferred to polarizing towards pro-inflammatory m1 subtype (inos+iba-1 +) in rat hippocampus post sevoflurane exposure, but not anti-inflammatory m2 subtype (arg-1 +iba-1 +). |
2021-11-18 |
2023-08-13 |
rat |
| Hongzhi Chen, Haichao Chu, Qian Jiang, Cong Wang, Yue Tia. Irf6 participates in sevoflurane-induced perioperative neurocognitive disorder via modulating M2, but not M1 polarization of microglia. Brain research bulletin. vol 177. 2021-11-18. PMID:34536519. |
co-immunofluorescence data further illustrated that sevoflurane decreased irf6 expression in hippocampal microglia. |
2021-11-18 |
2023-08-13 |
rat |
| Hongzhi Chen, Haichao Chu, Qian Jiang, Cong Wang, Yue Tia. Irf6 participates in sevoflurane-induced perioperative neurocognitive disorder via modulating M2, but not M1 polarization of microglia. Brain research bulletin. vol 177. 2021-11-18. PMID:34536519. |
collectively, these findings suggest that irf6 downregulation in hippocampal microglia may be a compensatory mechanism against sevoflurane-induced pnd in the elderly. |
2021-11-18 |
2023-08-13 |
rat |
| Jing-Yang Gu, Yao-Wei Xu, Lai-Peng Feng, Jiao Dong, Li-Qin Zhao, Cong Liu, Hui-Ying Wang, Xiang-Yang Zhang, Cai Song, Chang-Hong Wan. Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats. Brain research bulletin. vol 177. 2021-11-18. PMID:34653561. |
enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats. |
2021-11-18 |
2023-08-13 |
rat |
| Yunchang Mo, Lu Wang, Miao Ren, Wenjing Xie, Xiaoxiao Ye, Bingbing Zhou, Anqi Zhang, Qinxue Dai, Junlu Wan. Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus. Brain research bulletin. vol 177. 2021-11-18. PMID:34673136. |
electroacupuncture prevents lps- induced neuroinflammation via upregulation of pick-tlr4 complexes in the microglia of hippocampus. |
2021-11-18 |
2023-08-13 |
mouse |
| Armin Yazdani, Belal Howidi, Meng Zhu Shi, Nicol Tugarinov, Zehra Khoja, Pia Wintermar. Sildenafil improves hippocampal brain injuries and restores neuronal development after neonatal hypoxia-ischemia in male rat pups. Scientific reports. vol 11. issue 1. 2021-11-18. PMID:34764335. |
treatment with sildenafil preserved the gross morphology of the hippocampus, reverted the number of mature neurons to levels comparable to sham rats, significantly increased both the immature and mature oligodendrocytes, and significantly reduced the number of microglia and astrocytes. |
2021-11-18 |
2023-08-13 |
rat |
| Brittney Yegla, Jake Boles, Ashok Kumar, Thomas C Foste. Partial microglial depletion is associated with impaired hippocampal synaptic and cognitive function in young and aged rats. Glia. vol 69. issue 6. 2021-11-16. PMID:33586813. |
the role of microglia in mediating age-related changes in cognition and hippocampal synaptic function was examined by microglial depletion and replenishment using plx3397. |
2021-11-16 |
2023-08-13 |
rat |
| Jing Wang, Quanguang Zhang, Yujiao Lu, Yan Dong, Krishnan M Dhandapani, Darrell W Brann, Robert K Y. Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:34133773. |
here, we show that the b-series ganglioside gd3 and its biosynthetic enzyme, gd3-synthase (gd3s), were up-regulated predominantly in the microglia of mouse hippocampus from 2 to 7 days following global cerebral ischemia (gci). |
2021-11-16 |
2023-08-13 |
mouse |