All Relations between microglial cell and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Yoon-Jung Kim, So-Young Hwang, Ji-Sun Hwang, Jung-Weon Lee, Eok-Soo Oh, Inn-Oc Ha. C6 glioma cell insoluble matrix components enhance interferon-gamma-stimulated inducible nitric-oxide synthase/nitric oxide production in BV2 microglial cells. The Journal of biological chemistry. vol 283. issue 5. 2008-04-02. PMID:17981810. we found that ifn-gamma-stimulated inos induction and nitric oxide release was greater in microglia cultured on c6 glioma cell-derived matrices compared with microglia cultured on primary rat astrocyte-derived matrices. 2008-04-02 2023-08-12 rat
Michael Zeh, Peter Lorenz, Peter Kreutzmann, Peter Schönfel. Hydroxy-1-aryl-isochromans: protective compounds against lipid peroxidation and cellular nitrosative stress. Redox report : communications in free radical research. vol 13. issue 1. 2008-03-28. PMID:18284848. measurements of thiobarbituric acid reactive substances (tbars) in rat brain mitochondria, nitric oxide analysis in microglia cultures, and cell viability analysis were performed. 2008-03-28 2023-08-12 rat
Bin Xing, Tao Xin, Randy Lee Hunter, Guoying Bin. Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt. Journal of neuroinflammation. vol 5. 2008-03-27. PMID:18205920. in the present study we explored: (1) the effect of the ppar-gamma agonist pioglitazone on lipopolysaccharide (lps)-induced inos activity and nitric oxide (no) generation by microglia; (2) the differential role of p38 mitogen-activated protein kinase (p38 mapk), c-jun nh(2)-terminal kinase (jnk), and phosphoinositide 3-kinase (pi3k) on lps-induced no generation; and (3) the regulation of p38 mapk, jnk, and pi3k by pioglitazone. 2008-03-27 2023-08-12 Not clear
J J Neher, G C Brow. Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system. Biochemical Society transactions. vol 35. issue Pt 5. 2008-02-05. PMID:17956303. lta-activated microglia kill co-cultured neurons apparently via nitric oxide, superoxide and peroxynitrite, which may induce apoptosis of neurons that are then phagocytosed by microglia. 2008-02-05 2023-08-12 Not clear
Mitsuru Sato, Kazumasa Ogihara, Ryoko Sawahata, Kenji Sekikawa, Hiroshi Kitan. Impaired LPS-induced signaling in microglia overexpressing the Wiskott-Aldrich syndrome protein N-terminal domain. International immunology. vol 19. issue 8. 2008-01-25. PMID:17698982. furthermore, wasp tg microglia exhibited less cytotoxicity against co-cultured neurons after stimulation by lps and ifn-gamma, with a concordant decrease in nitric oxide production. 2008-01-25 2023-08-12 mouse
Shijie Jin, Jun Kawanokuchi, Tetsuya Mizuno, Jinyan Wang, Yoshifumi Sonobe, Hideyuki Takeuchi, Akio Suzumur. Interferon-beta is neuroprotective against the toxicity induced by activated microglia. Brain research. vol 1179. 2008-01-17. PMID:17905201. although ifn-beta enhanced the production of tumor necrosis factor (tnf)-alpha, interleukin (il)-1beta, and nitric oxide (no) by activated microglia, these molecules did not directly induce neurotoxicity in cultured cortical neurons. 2008-01-17 2023-08-12 Not clear
Doina Ganea, Elena Gonzalez-Rey, Mario Delgad. A novel mechanism for immunosuppression: from neuropeptides to regulatory T cells. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 1. issue 4. 2008-01-17. PMID:18040812. vip down-regulates the innate immune response by inhibiting the release of proinflammatory cytokines, chemokines, and nitric oxide by activated macrophages, microglia, and dendritic cells. 2008-01-17 2023-08-12 Not clear
Kyung-Hee Lee, Su-Jin Yun, Kyong Nyon Nam, Yong Song Gho, Eunjoo H Le. Activation of microglial cells by ceruloplasmin. Brain research. vol 1171. 2008-01-11. PMID:17727827. we observed that cp induced nitric oxide (no) release and inducible no synthase mrna expression in bv2 microglial cells and rat brain microglia. 2008-01-11 2023-08-12 rat
John B Schell, Courtney A Crane, Michael F Smith, Margo R Robert. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. Journal of neuroimmunology. vol 189. issue 1-2. 2007-11-28. PMID:17698208. differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. 2007-11-28 2023-08-12 mouse
John B Schell, Courtney A Crane, Michael F Smith, Margo R Robert. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. Journal of neuroimmunology. vol 189. issue 1-2. 2007-11-28. PMID:17698208. while the cytokine and chemokine responses of adult microglia were generally higher than those of neonatal cells stimulated ex vivo through tlrs, the nitric oxide response of neonatal microglia was markedly enhanced relative to the adult cells. 2007-11-28 2023-08-12 mouse
John B Schell, Courtney A Crane, Michael F Smith, Margo R Robert. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. Journal of neuroimmunology. vol 189. issue 1-2. 2007-11-28. PMID:17698208. we then went on to identify culture conditions such as exposure to m-scf or gm-csf that markedly enhanced the nitric oxide response of microglia, particularly those from the adult cns. 2007-11-28 2023-08-12 mouse
John B Schell, Courtney A Crane, Michael F Smith, Margo R Robert. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. Journal of neuroimmunology. vol 189. issue 1-2. 2007-11-28. PMID:17698208. finally, we demonstrate that the differential nitric oxide response of neonatal and adult microglia is not only limited to the mouse, but also extends to rat microglia. 2007-11-28 2023-08-12 mouse
Young Ae Kim, Gi-Young Kim, Kun-Young Park, Yung Hyun Cho. Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia. Journal of medicinal food. vol 10. issue 2. 2007-11-26. PMID:17651055. resveratrol inhibits nitric oxide and prostaglandin e2 production by lipopolysaccharide-activated c6 microglia. 2007-11-26 2023-08-12 rat
Young Ae Kim, Gi-Young Kim, Kun-Young Park, Yung Hyun Cho. Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia. Journal of medicinal food. vol 10. issue 2. 2007-11-26. PMID:17651055. in the present study, we investigated the effect of resveratrol on the production of nitric oxide (no) and prostaglandin (pg) e2 by lipopolysaccharide (lps)-activated c6 microglia. 2007-11-26 2023-08-12 rat
Luc Grandbarbe, Alessandro Michelucci, Tony Heurtaux, Karin Hemmer, Eleonora Morga, Paul Heuschlin. Notch signaling modulates the activation of microglial cells. Glia. vol 55. issue 15. 2007-11-20. PMID:17705199. notch stimulation in activated microglia, using a soluble form of its ligand jagged1, induces a decrease in pro-inflammatory cytokines secretion and nitric oxide production as well as an increase in phagocytic activity. 2007-11-20 2023-08-12 Not clear
Ryo Yamasaki, Jian Zhang, Ichiro Koshiishi, Dewi F Sastradipura Suniarti, Zhou Wu, Christoph Peters, Michael Schwake, Yasuo Uchiyama, Jun-Ichi Kira, Paul Saftig, Hideo Utsumi, Hiroshi Nakanish. Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice. Molecular and cellular neurosciences. vol 35. issue 4. 2007-10-30. PMID:17570679. involvement of lysosomal storage-induced p38 map kinase activation in the overproduction of nitric oxide by microglia in cathepsin d-deficient mice. 2007-10-30 2023-08-12 mouse
Ryo Yamasaki, Jian Zhang, Ichiro Koshiishi, Dewi F Sastradipura Suniarti, Zhou Wu, Christoph Peters, Michael Schwake, Yasuo Uchiyama, Jun-Ichi Kira, Paul Saftig, Hideo Utsumi, Hiroshi Nakanish. Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice. Molecular and cellular neurosciences. vol 35. issue 4. 2007-10-30. PMID:17570679. nitric oxide (no) and peroxynitrite, which are produced by activated microglia, are responsible for accelerated neurodegeneration in cathepsin d-deficient (cd-/-) mice. 2007-10-30 2023-08-12 mouse
Dong-Oh Moon, Sung-Yong Park, Kyeong-Jun Lee, Moon-Soo Heo, Ki-Cheon Kim, Mun-Ock Kim, Jae-Dong Lee, Yung Hyun Choi, Gi-Young Ki. Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia. International immunopharmacology. vol 7. issue 8. 2007-10-24. PMID:17570326. our results indicate that bv and mel suppress lps-induced nitric oxide (no) and inducible no synthase (inos) expression in a dose-dependent manner, without causing cytotoxicity in bv2 microglia. 2007-10-24 2023-08-12 bee
Qin Xiao, Weihua Zhao, David R Beers, Albert A Yen, Wenjie Xie, Jenny S Henkel, Stanley H Appe. Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. Journal of neurochemistry. vol 102. issue 6. 2007-10-19. PMID:17555556. following activation with lipopolysaccharide, msod1(g93a) microglia released more nitric oxide, more superoxide, and less insulin-like growth factor-1 than wild-type microglia. 2007-10-19 2023-08-12 mouse
Ju-Yu Wang, Jia-Yi Wan. Hypoxia/Reoxygenation induces nitric oxide and TNF-alpha release from cultured microglia but not astrocytes of the rat. The Chinese journal of physiology. vol 50. issue 3. 2007-10-19. PMID:17867433. hypoxia/reoxygenation induces nitric oxide and tnf-alpha release from cultured microglia but not astrocytes of the rat. 2007-10-19 2023-08-12 rat