All Relations between microglial cell and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Jun Tan, Terrence Town, Mike Mulla. CD40-CD40L interaction in Alzheimer's disease. Current opinion in pharmacology. vol 2. issue 4. 2002-12-31. PMID:12127879. reactive microglia produce potentially neurotoxic substances such as tumor necrosis factor alpha and the reactive oxygen species nitric oxide, which can induce bystander neuronal injury at high levels. 2002-12-31 2023-08-12 mouse
Candice M Brown, Elizabeth Wright, Carol A Colton, Patrick M Sullivan, Daniel T Laskowitz, Michael P Vite. Apolipoprotein E isoform mediated regulation of nitric oxide release. Free radical biology & medicine. vol 32. issue 11. 2002-12-02. PMID:12031891. primary cultures of microglial cells of apoe4 transgenic mice also produced significantly more nitric oxide than microglia from apoe3 transgenic mice. 2002-12-02 2023-08-12 mouse
Narayan R Bhat, Fan Fa. Adenovirus infection induces microglial activation: involvement of mitogen-activated protein kinase pathways. Brain research. vol 948. issue 1-2. 2002-10-30. PMID:12383959. exposure of cultured rat brain microglia to adv resulted in an induced production of nitric oxide (no) and the expression of inducible nitric oxide synthase (inos) and the pro-inflammatory cytokine, tnfalpha. 2002-10-30 2023-08-12 rat
A-J Hao, S T Dheen, E-A Lin. Expression of macrophage colony-stimulating factor and its receptor in microglia activation is linked to teratogen-induced neuronal damage. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088748. our results showed that reactive microglia were capable of releasing various cytokines such as tumor necrosis factor-alpha, interleukin-1, interleukin-6, transforming growth factor-beta and nitric oxide. 2002-09-03 2023-08-12 Not clear
Shun-Fen Tzeng, Jia-Ling Lee, Jon-Sun Kuo, Chung-Shi Yang, Periyagamy Murugan, Lin Ai Tai, Kuo Chu Hwan. Effects of malonate C60 derivatives on activated microglia. Brain research. vol 940. issue 1-2. 2002-08-29. PMID:12020876. although inducible nitric oxide (inos) mrna and protein expression in lps-activated microglia were slightly decreased by trans-2 and trans-3, levels of nitrate and nitrite were unaffected. 2002-08-29 2023-08-12 Not clear
Eun Joo Kim, Kyoung Ja Kwon, Jee Young Park, Soo Hwan Lee, Chang Hyun Moon, Eun Joo Bai. Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. Brain research. vol 941. issue 1-2. 2002-08-14. PMID:12031542. lps induced inos expression and the release of nitric oxide in microglia, and cox-2 expression in neurons. 2002-08-14 2023-08-12 Not clear
Heiko Possel, Heiko Noack, Gerburg Keilhoff, Gerald Wol. Life imaging of peroxynitrite in rat microglial and astroglial cells: Role of superoxide and antioxidants. Glia. vol 38. issue 4. 2002-08-07. PMID:12007146. free radicals, such as superoxide and nitric oxide, are known to play a role in a number of inflammatory and degenerative brain diseases, in which resident microglia upregulate the inducible nitric oxide synthase (inos) and thus produce large amounts of nitric oxide. 2002-08-07 2023-08-12 rat
Heiko Possel, Heiko Noack, Gerburg Keilhoff, Gerald Wol. Life imaging of peroxynitrite in rat microglial and astroglial cells: Role of superoxide and antioxidants. Glia. vol 38. issue 4. 2002-08-07. PMID:12007146. simultaneously, microglia generate superoxide mainly via nadph-oxidase, which reacts at a diffusion-limited rate with nitric oxide to form the powerful oxidant peroxynitrite. 2002-08-07 2023-08-12 rat
Sabine Golde, Siddharthan Chandran, Guy C Brown, Alastair Compsto. Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression. Journal of neurochemistry. vol 82. issue 2. 2002-08-06. PMID:12124428. activated microglia release two potential neurotoxins, excitatory amino acids and nitric oxide (no), but their contribution to mechanisms of injury is poorly understood. 2002-08-06 2023-08-12 rat
Cynthia L Cooper, Gwang-Ho Jeohn, Peter Tobias, Jau-Shyong Hon. Serum-dependence of LPS-induced neurotoxicity in rat cortical neurons. Annals of the New York Academy of Sciences. vol 962. 2002-07-26. PMID:12076983. a murine microglial cell line, bv2, was used to assess the serum dependence of nitric oxide production and tumor necrosis factor a release in microglia. 2002-07-26 2023-08-12 human
Bin Liu, Hui-Ming Gao, Jiz-Yuh Wang, Gwang-Ho Jeohn, Cynthia L Cooper, Jau-Shyong Hon. Role of nitric oxide in inflammation-mediated neurodegeneration. Annals of the New York Academy of Sciences. vol 962. 2002-07-26. PMID:12076984. the hallmark of brain inflammation is the activation of glial cells, especially that of microglia that produce a variety of proinflammatory and neurotoxic factors, including cytokines, fatty acid metabolites, free radicals--such as nitric oxide (no) and superoxide. 2002-07-26 2023-08-12 Not clear
Benoît Chénais, Hamid Morjani, Jean-Claude Drapie. Impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool. Journal of neurochemistry. vol 81. issue 3. 2002-07-05. PMID:12065670. impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool. 2002-07-05 2023-08-12 Not clear
Won-Gon Kim, Nan-Kyu Song, Ick-Dong Yo. Trienomycin G, a new inhibitor of nitric oxide production in microglia cells, from Streptomyces sp. 91614. The Journal of antibiotics. vol 55. issue 2. 2002-05-31. PMID:12003002. trienomycin g, a new inhibitor of nitric oxide production in microglia cells, from streptomyces sp. 2002-05-31 2023-08-12 Not clear
Zhong Xie, Min Wei, Todd E Morgan, Paola Fabrizio, Derick Han, Caleb E Finch, Valter D Long. Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978825. the amyloid beta-peptide (abeta) activates microglia and promotes the generation of cytokines and oxygen species, including nitric oxide (no) and tumor necrosis factor alpha (tnf-alpha), which can be either neurotoxic or neuroprotective. 2002-05-20 2023-08-12 rat
Jae K Ryu, Won H Shin, Jean Kim, Eun H Joe, Yong B Lee, Kyung G Cho, Young J Oh, Seung U Kim, Byung K Ji. Trisialoganglioside GT1b induces in vivo degeneration of nigral dopaminergic neurons: role of microglia. Glia. vol 38. issue 1. 2002-05-10. PMID:11921200. our results indicate that in vivo neurotoxicity of gt1b against nigral dopaminergic neurons is at least in part mediated by nitric oxide released from activated microglia. 2002-05-10 2023-08-12 rat
A K Cross, M N Woodroof. Immunoregulation of microglial functional properties. Microscopy research and technique. vol 54. issue 1. 2002-05-07. PMID:11526951. the products of activated microglia include: cytokines (pro- and anti-inflammatory), chemokines, nitric oxide, superoxide radicals, and proteases. 2002-05-07 2023-08-12 Not clear
A Wong, S Dukic-Stefanovic, J Gasic-Milenkovic, R Schinzel, H Wiesinger, P Riederer, G Münc. Anti-inflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia. The European journal of neuroscience. vol 14. issue 12. 2002-04-12. PMID:11860491. we show in this study that ages increase nitric oxide production by induction of the inducible nitric oxide synthase (inos) on the mrna and protein level in the murine microglial cell line n-11. 2002-04-12 2023-08-12 Not clear
B Halliwel. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs & aging. vol 18. issue 9. 2002-04-03. PMID:11599635. others are generated for useful purposes, such as the role of nitric oxide in neurotransmission and the production of o2*- by activated microglia. 2002-04-03 2023-08-12 Not clear
Simone Roberta De, Maria Antonietta Ajmone-Cat, Alessia Nicolini, Luisa Minghett. Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures. Journal of neuropathology and experimental neurology. vol 61. issue 3. 2002-03-27. PMID:11895038. the presence of ps-liposomes strongly reduced the release of pro-inflammatory molecules such as nitric oxide, interleukin-1beta, and tumor necrosis factor-alpha by lps-activated microglia. 2002-03-27 2023-08-12 rat
S Cuzzocrea, E Mazzon, L Sautebin, I Serraino, L Dugo, G Calabró, A P Caputi, A Magg. The protective role of endogenous estrogens in carrageenan-induced lung injury in the rat. Molecular medicine (Cambridge, Mass.). vol 7. issue 7. 2002-02-08. PMID:11683373. we have recently demonstrated that 17beta-estradiol (e2) inhibits the increase of inducible nitric oxide synthetase (inos) activity in selected model systems such as macrophages, microglia, smooth muscle cells, and proposed that this effect might be associated with an anti-inflammatory activity of this hormone. 2002-02-08 2023-08-12 rat