| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eoin Finegan, We Fong Siah, Stacey Li Hi Shing, Rangariroyashe H Chipika, Orla Hardiman, Peter Bed. Cerebellar degeneration in primary lateral sclerosis: an under-recognized facet of PLS. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2022-01-07. PMID:34991421. |
cerebellar manifestations are difficult to ascertain in pls as the clinical picture is dominated by widespread upper motor neuron signs. |
2022-01-07 |
2023-08-13 |
Not clear |
| Caleb J Murphy, Peter L Cathcart, Andrew P J Olso. Those eyes don't lie: a case of osmotic demyelination syndrome in a patient with hepatic encephalopathy. Diagnosis (Berlin, Germany). vol 3. issue 2. 2019-11-20. PMID:29536888. |
osmotic demyelination syndrome (ods), previously known as central pontine myelinolysis, is a rare neurological condition characterized by demyelination of the pons or extrapontine areas including the midbrain, thalamus, basal nuclei, and cerebellum, resulting in upper motor neuron dysfunction and pseudobulbar palsy. |
2019-11-20 |
2023-08-13 |
Not clear |
| Milos Stanojlovic, Xiaosha Pang, Yifeng Lin, Sarrabeth Stone, Marija Cvetanovic, Wensheng Li. Inhibition of Vascular Endothelial Growth Factor Receptor 2 Exacerbates Loss of Lower Motor Neurons and Axons during Experimental Autoimmune Encephalomyelitis. PloS one. vol 11. issue 7. 2017-08-02. PMID:27466819. |
interestingly, we found that treatment with su5416, a selective vegfr2 inhibitor, starting after the onset of eae clinical symptoms exacerbated lower motor neuron loss and axon loss in the lumbar spinal cord of mice undergoing eae, but did not alter purkinje neuron loss in the cerebellum or upper motor neuron loss in the cerebral cortex. |
2017-08-02 |
2023-08-13 |
mouse |
| Fayçal Hentati, Emna Hentati, Rim Amour. Giant axonal neuropathy. Handbook of clinical neurology. vol 115. 2014-04-01. PMID:23931822. |
clinically it is characterized by an age of onset during the first decade, progressive and severe motor sensory neuropathy followed, in some patients, by the occurrence of various central nervous system signs such as cerebellar syndrome, upper motor neuron signs, or epilepsy. |
2014-04-01 |
2023-08-12 |
Not clear |
| Joanne E Folker, Bruce E Murdoch, Louise M Cahill, Kristin M Rosen, Martin B Delatycki, Louise A Corben, Adam P Voge. Articulatory kinematics in the dysarthria associated with Friedreich's ataxia. Motor control. vol 15. issue 3. 2011-10-25. PMID:21878690. |
it is suggested that deviant lingual kinematics could be the outcome of disturbances to cerebellar function, or possibly in combination with disturbances to upper motor neuron systems. |
2011-10-25 |
2023-08-12 |
human |
| Geneviève Bernard, Isabelle Thiffault, Martine Tetreault, Maria Lisa Putorti, Isabelle Bouchard, Michel Sylvain, Serge Melançon, Rachel Laframboise, Pierre Langevin, Jean-Pierre Bouchard, Michel Vanasse, Adeline Vanderver, Guillaume Sébire, Bernard Brai. Tremor-ataxia with central hypomyelination (TACH) leukodystrophy maps to chromosome 10q22.3-10q23.31. Neurogenetics. vol 11. issue 4. 2011-01-18. PMID:20640464. |
all cases presented between the ages of 1 and 5 years with spasticity along with other upper motor neuron signs, prominent postural tremor, and cerebellar signs. |
2011-01-18 |
2023-08-12 |
Not clear |
| N Chakraborty, T Roy, A Hazra, A Biswas, K Bhattachary. Dysarthric Bengali speech: a neurolinguistic study. Journal of postgraduate medicine. vol 54. issue 4. 2009-05-07. PMID:18953144. |
dysarthria affects linguistic domains such as respiration, phonation, articulation, resonance and prosody due to upper motor neuron, lower motor neuron, cerebellar or extrapyramidal tract lesions. |
2009-05-07 |
2023-08-12 |
Not clear |
| S Singh, T Soloman, G Chacko, T P Josep. Primary angiitis of the central nervous system: an ante-mortem diagnosis. Journal of postgraduate medicine. vol 46. issue 4. 2001-10-11. PMID:11435655. |
she had left seventh nerve upper motor neuron type paresis, increased tone in all four limbs, exaggerated deep tendon reflexes, cerebellar signs, and papilloedema. |
2001-10-11 |
2023-08-12 |
Not clear |
| L P Erasmus, S Sarno, H Albrecht, M Schwecht, W Pöllmann, N Köni. Measurement of ataxic symptoms with a graphic tablet: standard values in controls and validity in Multiple Sclerosis patients. Journal of neuroscience methods. vol 108. issue 1. 2001-09-20. PMID:11459615. |
three hundred and forty-two consecutive patients with different symptoms in the upper limbs (upper motor neuron symptoms, cerebellar upper limb ataxia, and/or sensory deficits in the upper limbs) and 140 healthy controls took part in the study. |
2001-09-20 |
2023-08-12 |
Not clear |
| N Turjanski, A J Lees, D J Brook. Dopaminergic function in patients with posttraumatic parkinsonism: an 18F-dopa PET study. Neurology. vol 49. issue 1. 1997-09-03. PMID:9222188. |
posttraumatic encephalopathy (pte) is characterized by a combination of upper motor neuron, basal ganglia, cerebellar, and psychiatric disturbances. |
1997-09-03 |
2023-08-12 |
Not clear |
| I Darian-Smith, M P Galea, C Darian-Smit. Manual dexterity: how does the cerebral cortex contribute? Clinical and experimental pharmacology & physiology. vol 23. issue 10-11. 1997-02-19. PMID:8911739. |
each corticospinal neuron population has a unique thalamic input which can relay particular sensorimotor information from the sense organs, cerebellum and basal ganglia. |
1997-02-19 |
2023-08-12 |
monkey |
| G G Gascon, P Chavis, A Yaghmour, B Stigsby, A Shums, P Ozand, T Siddiqu. Familial childhood primary lateral sclerosis with associated gaze paresis. Neuropediatrics. vol 26. issue 6. 1996-10-28. PMID:8719747. |
examination revealed upper motor neuron findings of pseudobulbar palsy and spastic quadriplegia, without dementia, cerebellar, extrapyramidal or sensory signs. |
1996-10-28 |
2023-08-12 |
Not clear |
| A Berardelli, M Hallett, J C Rothwell, R Agostino, M Manfredi, P D Thompson, C D Marsde. Single-joint rapid arm movements in normal subjects and in patients with motor disorders. Brain : a journal of neurology. vol 119 ( Pt 2). 1996-10-01. PMID:8800955. |
in this paper, we also review the emg and kinematic abnormalities that are present during the execution of single-joint, rapid arm movements in patients with parkinson's disease, huntington's disease, sydenham's chorea, dystonia, athetosis, cerebellar deficits, upper motor neuron syndrome, essential tremor and large-fibre sensory neuropathy. |
1996-10-01 |
2023-08-12 |
human |
| V M Der Kaloustian, N I Jarudi, M J Khoury, A K Afifi, N B Bahuth, M E Deeb, J Shammas, M A Mikat. Familial spinocerebellar degeneration with corneal dystrophy. American journal of medical genetics. vol 20. issue 2. 1985-04-10. PMID:3872072. |
their manifestations include mental subnormality, bilateral corneal opacification starting in the second year of life and leading to severe visual impairment, and slowly progressive cerebellar abnormalities with variable dorsal column and upper motor neuron involvement. |
1985-04-10 |
2023-08-11 |
Not clear |
| J Egger, B D Lake, J Wilso. Mitochondrial cytopathy. A multisystem disorder with ragged red fibres on muscle biopsy. Archives of disease in childhood. vol 56. issue 10. 1982-01-28. PMID:7305411. |
thirteen children with abnormal mitochondria in muscle tissue, and a progressive neurological disorder that affected the cerebrum, cerebellum, extrapyramidal system, vestibular system, retina, upper motor neuron, lower motor neuron, and musculature, are reported. |
1982-01-28 |
2023-08-12 |
Not clear |
| P H Ward, D G Hanson, G Berc. Photographic studies of the larynx in central laryngeal paresis and paralysis. Acta oto-laryngologica. vol 91. issue 5-6. 1981-10-29. PMID:7270110. |
representative patients are used to describe typical patterns of abnormal laryngeal function which occur in upper motor neuron, extrapyramidal, cerebellar, nuclear and mixed foci of lesions. |
1981-10-29 |
2023-08-12 |
Not clear |
| J A Logemann, B Boshes, E R Blonsky, H B Fishe. Speech and swallowing evaluation in the differential diagnosis of neurologic disease. Neurologia, neurocirugia, psiquiatria. vol 18. issue 2-3 Suppl. 1978-11-29. PMID:616561. |
the speech, swallowing and respiratory patterns of patients with cerebellar, upper motor neuron, lower motor neuron and extra-pyramidal lesions (parkinsonism) were studied, 10 of each category. |
1978-11-29 |
2023-08-11 |
Not clear |
| M A Diamond, R H Murray, P G Schmi. Idiopathic postural hypotension: physiologic observations and report of a new mode of therapy. The Journal of clinical investigation. vol 49. issue 7. 1970-09-11. PMID:5432369. |
two patients with severe postural hypotension associated with upper motor neuron and cerebellar impairment (shy-drager syndrome) have been studied. |
1970-09-11 |
2023-08-11 |
Not clear |