| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abdessattar Khlaifia, Eve Honoré, Julien Artinian, Isabel Laplante, Jean-Claude Lacaill. mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination. Molecular brain. vol 15. issue 1. 2022-06-17. PMID:35715811. |
hippocampal ca1 parvalbumin-expressing interneurons (pv ins) play a central role in controlling principal cell activity and orchestrating network oscillations. |
2022-06-17 |
2023-08-14 |
Not clear |
| Hannah Twarkowksi, Victor Steininger, Min Jae Kim, Amar Saha. A dentate gyrus- CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. eLife. vol 11. 2022-02-22. PMID:35191834. |
although ca1 parvalbumin inhibitory neurons (pv ins) orchestrate hippocampal-cortical communication, we know less about ca3 pv ins or dg - ca3 principal neuron - in circuit mechanisms that contribute to evolution of hippocampal-cortical ensembles during memory consolidation. |
2022-02-22 |
2023-08-13 |
Not clear |
| Davide Cavalieri, Alexandra Angelova, Anas Islah, Catherine Lopez, Marco Bocchio, Yannick Bollmann, Agnès Baude, Rosa Cossar. CA1 pyramidal cell diversity is rooted in the time of neurogenesis. eLife. vol 10. 2021-12-09. PMID:34723790. |
using a combination of neuroanatomy, slice physiology, connectivity tracing, and cfos staining in mice, we show that birthdate is a strong predictor of ca1 principal cell diversity. |
2021-12-09 |
2023-08-13 |
mouse |
| Xia Liang, Li-Ming Hsu, Hanbing Lu, Jessica A Ash, Peter R Rapp, Yihong Yan. Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32239141. |
the ca3 and ca1 principal cell fields of the hippocampus are vulnerable to aging, and age-related dysfunction in ca3 may be an early seed event closely linked to individual differences in memory decline. |
2021-11-29 |
2023-08-13 |
rat |
| Julie Faitg, Clay Lacefield, Tracey Davey, Kathryn White, Ross Laws, Stylianos Kosmidis, Amy K Reeve, Eric R Kandel, Amy E Vincent, Martin Picar. 3D neuronal mitochondrial morphology in axons, dendrites, and somata of the aging mouse hippocampus. Cell reports. vol 36. issue 6. 2021-09-09. PMID:34380033. |
we examine somatic, dendritic, and axonal mitochondria in the dentate gyrus and cornu ammonis 1 (ca1) of the mouse hippocampus, two subregions with distinct principal cell types and functions. |
2021-09-09 |
2023-08-13 |
mouse |
| Heiko Braak, Kelly Del Tredic. From the Entorhinal Region via the Prosubiculum to the Dentate Fascia: Alzheimer Disease-Related Neurofibrillary Changes in the Temporal Allocortex. Journal of neuropathology and experimental neurology. vol 79. issue 2. 2020-07-27. PMID:31913466. |
such a progression might recapitulate a sequence of transsynaptic spreading of abnormal tau from 1 projection neuron to the next: from pre-α cells to distal dendrites in the prosubiculum and ca1; then, from ca1 or prosubicular pyramids to ca2 principal cells and ca3/ca4 mossy cells; finally, from ca4 mossy cells to dentate granule cells. |
2020-07-27 |
2023-08-13 |
Not clear |
| Nicolette Ognjanovski, Christopher Broussard, Michal Zochowski, Sara J Ato. Hippocampal Network Oscillations Rescue Memory Consolidation Deficits Caused by Sleep Loss. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 10. 2019-11-06. PMID:30060138. |
rhythmic optogenetic activation of pv+ interneurons following learning generates ca1 oscillations with coherent principal neuron firing. |
2019-11-06 |
2023-08-13 |
mouse |
| Ivan Soltesz, Attila Losoncz. CA1 pyramidal cell diversity enabling parallel information processing in the hippocampus. Nature neuroscience. vol 21. issue 4. 2019-05-16. PMID:29593317. |
however, heterogeneity within hippocampal principal cell populations, in particular within pyramidal cells at the main ca1 output node, is increasingly recognized and includes developmental, molecular, anatomical, and functional differences. |
2019-05-16 |
2023-08-13 |
Not clear |
| D J Hamilton, C M White, C L Rees, D W Wheeler, G A Ascol. Molecular fingerprinting of principal neurons in the rodent hippocampus: A neuroinformatics approach. Journal of pharmaceutical and biomedical analysis. vol 144. 2018-02-05. PMID:28549853. |
here we focus on the principal cell layers of dentate gyrus (dg), ca3, ca2, and ca1, which together contain approximately 90% of hippocampal neurons. |
2018-02-05 |
2023-08-13 |
mouse |
| D J Hamilton, C M White, C L Rees, D W Wheeler, G A Ascol. Molecular fingerprinting of principal neurons in the rodent hippocampus: A neuroinformatics approach. Journal of pharmaceutical and biomedical analysis. vol 144. 2018-02-05. PMID:28549853. |
thus, gene expression data for those layers can be justifiably linked to the respective principal neuron types: granule cells in dg and pyramidal cells in ca3, ca2, and ca1. |
2018-02-05 |
2023-08-13 |
mouse |
| Antonio Fernández-Ruiz, Azahara Oliva, Gergő A Nagy, Andrew P Maurer, Antal Berényi, György Buzsák. Entorhinal-CA3 Dual-Input Control of Spike Timing in the Hippocampus by Theta-Gamma Coupling. Neuron. vol 93. issue 5. 2017-09-14. PMID:28279355. |
the theta-phase preference and excitatory strength of the afferent ca3 and entorhinal inputs effectively timed the principal neuron activity, as well as regulated distinct ca1 interneuron populations in multiple tasks and behavioral states. |
2017-09-14 |
2023-08-13 |
Not clear |
| Sitthisak Thongrong, Barbara Hausott, Letizia Marvaldi, Alexandra S Agostinho, Luca Zangrandi, Johannes Burtscher, Barbara Fogli, Christoph Schwarzer, Lars Klimaschewsk. Sprouty2 and -4 hypomorphism promotes neuronal survival and astrocytosis in a mouse model of kainic acid induced neuronal damage. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26540287. |
neuronal degeneration was reduced in ca1 and ca3 principal neuron layers as well as in scattered neurons of the contralateral ca1 and hilar regions. |
2017-01-06 |
2023-08-13 |
mouse |
| Bénédicte Amilhon, Carey Y L Huh, Frédéric Manseau, Guillaume Ducharme, Heather Nichol, Antoine Adamantidis, Sylvain William. Parvalbumin Interneurons of Hippocampus Tune Population Activity at Theta Frequency. Neuron. vol 86. issue 5. 2015-08-24. PMID:26050044. |
interneurons expressing the markers parvalbumin (pv) and somatostatin (som) are leading candidates to participate in intrinsic rhythm generation and principal cell (pc) coordination in distal ca1 and subiculum. |
2015-08-24 |
2023-08-13 |
Not clear |
| Andrea Bibbig, Steven Middleton, Claudia Racca, Martin J Gillies, Helen Garner, Fiona E N Lebeau, Ceri H Davies, Miles A Whittingto. Beta rhythms (15-20 Hz) generated by nonreciprocal communication in hippocampus. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17287437. |
1) in conditions where activity projected to area ca1 produces only very low principal cell recruitment the local population rhythm mimics the gamma rhythm projected from ca3. |
2007-07-10 |
2023-08-12 |
Not clear |
| Andrea Bibbig, Steven Middleton, Claudia Racca, Martin J Gillies, Helen Garner, Fiona E N Lebeau, Ceri H Davies, Miles A Whittingto. Beta rhythms (15-20 Hz) generated by nonreciprocal communication in hippocampus. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17287437. |
2) in the presence of serotonin ca1 principal cell recruitment was appreciably enhanced, resulting in dual activation of ca1 basket cells through both feedforward and feedback excitations. |
2007-07-10 |
2023-08-12 |
Not clear |
| Chyze W Ang, Gregory C Carlson, Douglas A Coulte. Hippocampal CA1 circuitry dynamically gates direct cortical inputs preferentially at theta frequencies. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 42. 2006-03-15. PMID:16237162. |
therefore, ca1 circuit integration of excitatory inputs endows the ca1 principal cell with a novel property: the ability to function as a temporally specific "and" gate that provides for sequence-dependent readout of distal inputs. |
2006-03-15 |
2023-08-12 |
Not clear |
| Douglas Nitz, Bruce McNaughto. Differential modulation of CA1 and dentate gyrus interneurons during exploration of novel environments. Journal of neurophysiology. vol 91. issue 2. 2004-03-31. PMID:14523073. |
the data indicate that inhibitory networks in the ca1 and dentate gyrus areas are modulated in a divergent fashion during the acquisition of novel spatial information and that interneuron activities can be used to detect those regions of an environment subject to redistribution of principal cell spatial activity patterns. |
2004-03-31 |
2023-08-12 |
human |
| Martin Theis, Kausik Si, Eric R Kande. Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 16. 2003-10-03. PMID:12871996. |
we next examined the expression of all four genes in the hippocampus and found that mcpeb-1, -2, and -4 transcripts are expressed in the principal cell layer in the ca3 and ca1 region and in the dentate gyrus of the hippocampus. |
2003-10-03 |
2023-08-12 |
mouse |
| Johannes Graulich, Ulrike Hoffmann, Rolf F Maier, Karsten Ruscher, Jörn K Pomper, Hae-Kyung Ko, Siegrun Gabriel, Michael Obladen, Uwe Heineman. Acute neuronal injury after hypoxia is influenced by the reoxygenation mode in juvenile hippocampal slice cultures. Brain research. Developmental brain research. vol 137. issue 1. 2002-10-16. PMID:12128252. |
pi fluorescence increased after hypoxia in all principal cell layers of the hippocampus but again showed a larger enhancement after hyperoxic reoxygenation as compared to normoxic reoxygenation (e.g., by a factor of 3.9 vs. 1.7 for ca1 and 120 min of hypoxia). |
2002-10-16 |
2023-08-12 |
rat |
| E D Kirson, Y Yaar. Unique properties of NMDA receptors enhance synaptic excitation of radiatum giant cells in rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 13. 2000-07-26. PMID:10864941. |
we used the whole-cell patch-clamp technique in adult hippocampal slices to assess the role of nmda receptors in synaptic excitation of a recently discovered excitatory projection neuron, the ca1 radiatum giant cell (rgc). |
2000-07-26 |
2023-08-12 |
rat |