| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huicong Li, Yunqian Wang, Baoping Chen, Jun Sh. Silencing of PAQR3 suppresses extracellular matrix accumulation in high glucose-stimulated human glomerular mesangial cells via PI3K/AKT signaling pathway. European journal of pharmacology. vol 832. 2018-10-08. PMID:29787774. |
therefore, in this study, we investigated the effects of paqr3 on cell proliferation and extracellular matrix (ecm) accumulation in human glomerular mesangial cells (mcs) cultured under high glucose (hg), and explored the underlying mechanism. |
2018-10-08 |
2023-08-13 |
human |
| Lavinia Arseni, Anita Lombardi, Donata Oriol. From Structure to Phenotype: Impact of Collagen Alterations on Human Health. International journal of molecular sciences. vol 19. issue 5. 2018-09-20. PMID:29738498. |
we discuss the different functions of the ecm including its impact on cell proliferation, migration and differentiation by highlighting the relevance of the bidirectional cross-talk between the matrix and surrounding cells. |
2018-09-20 |
2023-08-13 |
human |
| Anthony Hayes, Kazuyuki Sugahara, Brooke Farrugia, John M Whitelock, Bruce Caterson, James Melros. Biodiversity of CS-proteoglycan sulphation motifs: chemical messenger recognition modules with roles in information transfer, control of cellular behaviour and tissue morphogenesis. The Biochemical journal. vol 475. issue 3. 2018-09-14. PMID:29439148. |
chondroitin sulphate (cs) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (pgs) can no longer be regarded as merely hydrodynamic space fillers. |
2018-09-14 |
2023-08-13 |
Not clear |
| Chen Lin, Liyi Xie, Yan Lu, Zhihuang Hu, Jianhua Chan. miR-133b reverses cisplatin resistance by targeting GSTP1 in cisplatin-resistant lung cancer cells. International journal of molecular medicine. vol 41. issue 4. 2018-08-29. PMID:29328427. |
in addition, the knockdown of gstp1 by transfection with small interfering rna exerted similar effects on cell chemosensitivity, proliferation and migration as did ectopic mir‑133b expression, in addition to the upregulation of bax and downregulation of bcl‑2, survivin and matrix metalloproteinase expression. |
2018-08-29 |
2023-08-13 |
Not clear |
| Cheng-Hsun Lu, Chia-Huei Lin, Ko-Jen Li, Chieh-Yu Shen, Cheng-Han Wu, Yu-Min Kuo, Ting-Syuan Lin, Chia-Li Yu, Song-Chou Hsie. Intermediate Molecular Mass Hyaluronan and CD44 Receptor Interactions Enhance Neutrophil Phagocytosis and IL-8 Production via p38- and ERK1/2-MAPK Signalling Pathways. Inflammation. vol 40. issue 5. 2018-08-15. PMID:28730511. |
hyaluronan (ha), the natural ligand of cd44, is a simple repeated disaccharide with variable molecular mass that is widely distributed on cell surfaces and the connective tissue matrix. |
2018-08-15 |
2023-08-13 |
Not clear |
| Ji-Young Um, Seoung-Ae Lee, Joo-Hoo Park, Jae-Min Shin, Il-Ho Park, Heung-Man Le. Role of adenosine monophosphate-activated protein kinase on cell migration, matrix contraction, and matrix metalloproteinase-1 and matrix metalloproteinase-2 production in nasal polyp-derived fibroblasts. American journal of rhinology & allergy. vol 31. issue 6. 2018-08-08. PMID:29122080. |
role of adenosine monophosphate-activated protein kinase on cell migration, matrix contraction, and matrix metalloproteinase-1 and matrix metalloproteinase-2 production in nasal polyp-derived fibroblasts. |
2018-08-08 |
2023-08-13 |
Not clear |
| Ji-Young Um, Seoung-Ae Lee, Joo-Hoo Park, Jae-Min Shin, Il-Ho Park, Heung-Man Le. Role of adenosine monophosphate-activated protein kinase on cell migration, matrix contraction, and matrix metalloproteinase-1 and matrix metalloproteinase-2 production in nasal polyp-derived fibroblasts. American journal of rhinology & allergy. vol 31. issue 6. 2018-08-08. PMID:29122080. |
here, we investigated the physical role of ampk on cell migration, matrix contraction, and the production of matrix metalloproteinases (mmp) in nasal polyp-derived fibroblasts (npdf). |
2018-08-08 |
2023-08-13 |
Not clear |
| Dingqing Feng, Tingting Zhao, Keqin Yan, Haiyan Liang, Jing Liang, Ying Zhou, Weidong Zhao, Bin Lin. Gonadotropins promote human ovarian cancer cell migration and invasion via a cyclooxygenase 2-dependent pathway. Oncology reports. vol 38. issue 2. 2018-07-23. PMID:28677781. |
further results showed that enhancement of epithelial-mesenchymal transition (emt) and upregulation of matrix metalloproteinase (mmp)2 and mmp9 contributed to the stimulatory effect of gonadotropins on cell migration and invasion; these effects were sufficiently blocked by a selective cox2 inhibitor. |
2018-07-23 |
2023-08-13 |
human |
| David O Prichard, Anne Marie Byrne, James O Murphy, John V Reynolds, Jacintha O'Sullivan, Ronan Feighery, Brendan Doyle, Osama Sharaf Eldin, Stephen P Finn, Aoife Maguire, Deirdre Duff, Dermot P Kelleher, Aideen Lon. Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-αv trafficking. Journal of cellular and molecular medicine. vol 21. issue 12. 2018-07-18. PMID:28941013. |
cell line models of squamous epithelium (het-1a) and bo (qh) were used to examine the effects of bile acids on cell adhesion to extracellular matrix proteins (collagen, laminin, vitronectin, fibronectin) and expression of integrin ligands (α |
2018-07-18 |
2023-08-13 |
Not clear |
| Mingqi Qu, Ju Yu, Hongyuan Liu, Ying Ren, Chunxiao Ma, Xingyao Bu, Qing La. The Candidate Tumor Suppressor Gene SLC8A2 Inhibits Invasion, Angiogenesis and Growth of Glioblastoma. Molecules and cells. vol 40. issue 10. 2018-07-09. PMID:29047259. |
overexpression of slc8a2 had no effect on cell proliferation or cell cycle, but impaired the invasion and migration of u87mg cells, most likely through inactivating the extracellular signal-related kinases (erk)1/2 signaling pathway, inhibiting the nuclear translocation and dna binding activity of nuclear factor kappa b (nf-κb), reducing the level of matrix metalloproteinases (mmps) and urokinase-type plasminogen activator (upa)-its receptor (upar) system (erk1/2-nf-κb-mmps/upa-upar), and altering the protein levels of epithelial to mesenchymal transitions (emt)-associated proteins e-cardherin, vimentin and snail. |
2018-07-09 |
2023-08-13 |
mouse |
| Alicia Marsà, Constanza Cortés, Elisabet Teixidó, Alba Hernández, Ricard Marco. In vitro studies on the tumorigenic potential of the halonitromethanes trichloronitromethane and bromonitromethane. Toxicology in vitro : an international journal published in association with BIBRA. vol 45. issue Pt 1. 2018-06-25. PMID:28844819. |
the results indicate that long-term exposure to non-cytotoxic doses of tcnm and bnm did not cause carcinogenic transformation as indicated by the absence of morphological changes, no effects on cell growth, no changes in the level of matrix metalloproteinases (mmps) secretion, and no increased anchorage-independent cell growth capacity. |
2018-06-25 |
2023-08-13 |
human |
| Walter Mandaliti, Ridvan Nepravishta, Francesca Pica, Paola Sinibaldi Vallebona, Enrico Garaci, Maurizio Pac. Thymosin α1 Interacts with Hyaluronic Acid Electrostatically by Its Terminal Sequence LKEKK. Molecules (Basel, Switzerland). vol 22. issue 11. 2018-06-19. PMID:29077041. |
hyaluronan (ha) occurs ubiquitously in the extracellular matrix and on cell surfaces and has been related to a variety of diseases, and developmental and physiological processes. |
2018-06-19 |
2023-08-13 |
Not clear |
| Carlos J Arias, Richard L Surmaitis, Joseph B Schlenof. Cell Adhesion and Proliferation on the "Living" Surface of a Polyelectrolyte Multilayer. Langmuir : the ACS journal of surfaces and colloids. vol 32. issue 21. 2018-06-05. PMID:27191244. |
a comprehensive view of cell adhesion highlights the central role of robust protein adhesion, which is required before any secondary effects of matrix stiffness on cell fate can come into play. |
2018-06-05 |
2023-08-13 |
Not clear |
| Carrie Spencer, Stephanie Abend, Kevin J McHugh, Magali Saint-Genie. Identification of a synergistic interaction between endothelial cells and retinal pigment epithelium. Journal of cellular and molecular medicine. vol 21. issue 10. 2018-06-05. PMID:28402065. |
using a physiological long-term co-culture system, we determined the effect of retinal pigment epithelium-endothelial cell heterotypic interactions on cell survival, behaviour and matrix deposition. |
2018-06-05 |
2023-08-13 |
human |
| Tsai-Der Chuang, Omid Khorra. Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells. Reproductive sciences (Thousand Oaks, Calif.). vol 24. issue 9. 2018-05-11. PMID:28114878. |
tranilast (n-3,4-dimethoxycinnamoyl anthranilic acid) is an antiallergic agent with inhibitory effects on cell proliferation and extracellular matrix production. |
2018-05-11 |
2023-08-13 |
Not clear |
| Marianne R Sommer, Jolanda R Vetsch, Jessica Leemann, Ralph Müller, André R Studart, Sandra Hofman. Silk fibroin scaffolds with inverse opal structure for bone tissue engineering. Journal of biomedical materials research. Part B, Applied biomaterials. vol 105. issue 7. 2018-05-09. PMID:27407014. |
while cell number remained similar on both scaffold types, extracellular matrix mineralization nearly doubled on the newly developed scaffolds, suggesting a positive effect on cell differentiation. |
2018-05-09 |
2023-08-13 |
human |
| Claudia Tresoldi, Ilaria Stefani, Gaia Ferracci, Serena Bertoldi, Alessandro F Pellegata, Silvia Farè, Sara Manter. Alternating air-medium exposure in rotating bioreactors optimizes cell metabolism in 3D novel tubular scaffold polyurethane foams. Journal of applied biomaterials & functional materials. vol 15. issue 2. 2018-05-07. PMID:28362040. |
for tubular scaffolds, mass transfer is enhanced by introducing a convective flow through rotating bioreactors with positive effects on cell proliferation, scaffold colonization and extracellular matrix deposition. |
2018-05-07 |
2023-08-13 |
Not clear |
| Elza D van Deel, Aref Najafi, Dulce Fontoura, Erik Valent, Max Goebel, Kim Kardux, Inês Falcão-Pires, Jolanda van der Velde. In vitro model to study the effects of matrix stiffening on Ca The Journal of physiology. vol 595. issue 14. 2018-04-17. PMID:28485491. |
detachment of adult cardiomyocytes from the matrix enables the study of matrix effects on cell shortening, ca |
2018-04-17 |
2023-08-13 |
Not clear |
| Yuan Jiang, Jinlu Dai, Zhi Yao, Greg Shelley, Evan T Kelle. Abituzumab Targeting of αV-Class Integrins Inhibits Prostate Cancer Progression. Molecular cancer research : MCR. vol 15. issue 7. 2018-04-02. PMID:28314844. |
di17e6 promoted detachment and inhibited adhesion of prostate cancer cells to several extracellular matrix (ecm) proteins and cells found in the bone microenvironment but had no impact on cell viability, cell-cycle, and caspase-3/7 activity. |
2018-04-02 |
2023-08-13 |
Not clear |
| Penney M Gilbert, Valerie M Weave. Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Seminars in cell & developmental biology. vol 67. 2018-03-22. PMID:27641825. |
this review will highlight recent advances that elucidate the impact of matrix mechanics on cell behavior and fate across these length scales during times of homeostasis and in disease states. |
2018-03-22 |
2023-08-13 |
human |