| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Perla Ayala, Jose I Lopez, Tejal A Desa. Microtopographical cues in 3D attenuate fibrotic phenotype and extracellular matrix deposition: implications for tissue regeneration. Tissue engineering. Part A. vol 16. issue 8. 2011-01-25. PMID:20235832. |
in this work, the effect of discrete micromechanical cues in three-dimensional (3d) system on cell proliferation, gene expression, and extracellular matrix synthesis was investigated. |
2011-01-25 |
2023-08-12 |
Not clear |
| Lin Gao, Robert S Smith, Li-Mei Chen, Karl X Chai, Lee Chao, Julie Cha. Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway. Biological chemistry. vol 391. issue 7. 2011-01-14. PMID:20482314. |
the effect of tk on cell migration and invasion are also blocked by inhibitors of protein kinase c, c-src, matrix metalloproteinase, egfr and extracellular signal-regulated kinase (erk). |
2011-01-14 |
2023-08-12 |
Not clear |
| Craig Horbinski, Colton Mojesky, Natasha Kypriano. Live free or die: tales of homeless (cells) in cancer. The American journal of pathology. vol 177. issue 3. 2010-12-13. PMID:20639456. |
anoikis, programed cell death that occurs on cell detachment from the extracellular matrix, thus disrupting integrin-ligand interactions, is a critical mechanism in preventing ectopic cell growth or attachment to an inappropriate matrix. |
2010-12-13 |
2023-08-12 |
Not clear |
| Young-Eun Cho, Ethel Alcantara, Santhy Kumaran, Kun-Ho Son, Ho-Yong Sohn, Jong-Hwa Lee, Chung-Sig Choi, Tae-Youl Ha, In-Sook Kwu. Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells. Nutrition research (New York, N.Y.). vol 30. issue 7. 2010-12-10. PMID:20797483. |
this cellular alp activity stimulation by ryrp extract was confirmed by the staining of alp activity on cell matrix layers for matrix calcification. |
2010-12-10 |
2023-08-12 |
Not clear |
| Tina Manon-Jensen, Yoshifumi Itoh, John R Couchma. Proteoglycans in health and disease: the multiple roles of syndecan shedding. The FEBS journal. vol 277. issue 19. 2010-10-27. PMID:20840585. |
proteolytic processes in the extracellular matrix are a major influence on cell adhesion, migration, survival, differentiation and proliferation. |
2010-10-27 |
2023-08-12 |
Not clear |
| Frederick Grinnell, W Matthew Petrol. Cell motility and mechanics in three-dimensional collagen matrices. Annual review of cell and developmental biology. vol 26. 2010-10-26. PMID:19575667. |
we describe several matrix contraction models, the interactions between fibroblasts and collagen fibrils at global and subcellular levels, unique features of mechanical feedback between cells and the matrix, and the impact of the cell-matrix tension state on cell morphology and mechanical behavior. |
2010-10-26 |
2023-08-12 |
Not clear |
| Chun-Jen Huang, Po-Yuan Tseng, Ying-Chih Chan. Effects of extracellular matrix protein functionalized fluid membrane on cell adhesion and matrix remodeling. Biomaterials. vol 31. issue 27. 2010-10-07. PMID:20580428. |
effects of extracellular matrix protein functionalized fluid membrane on cell adhesion and matrix remodeling. |
2010-10-07 |
2023-08-12 |
Not clear |
| Barbara Wegiel, Jenny L Persso. Effect of a novel botanical agent Drynol Cibotin on human osteoblast cells and implications for osteoporosis: promotion of cell growth, calcium uptake and collagen production. Phytotherapy research : PTR. vol 24 Suppl 2. 2010-09-20. PMID:19953582. |
the effects of drynol cibotin on cell growth, apoptosis, cell spreading, calcium uptake and production of bone matrix proteins collagen i and laminin b2 on human osteoblast cells were assessed by brdu incorporation, tunel assay, cell staining, intracellular ca2+ measurement and western blot analysis. |
2010-09-20 |
2023-08-12 |
human |
| Yufeng Zhang, Wei Fan, Zhaocheng Ma, Chengtie Wu, Wei Fang, Gang Liu, Yin Xia. The effects of pore architecture in silk fibroin scaffolds on the growth and differentiation of mesenchymal stem cells expressing BMP7. Acta biomaterialia. vol 6. issue 8. 2010-09-13. PMID:20188872. |
a cell viability colorimetric assay, alkaline phosphatase assay and reverse transcription-polymerase chain reaction were performed to analyze the effect of pore size on cell growth, the secretion of extracellular matrix (ecm) and osteogenic differentiation. |
2010-09-13 |
2023-08-12 |
mouse |
| Yihui Shi, Khalid Amin, Barbara G Sato, Steven J Samuelsson, Lidia Sambucetti, Zishan A Haroon, Keith Laderoute, Brian J Murph. The metal-responsive transcription factor-1 protein is elevated in human tumors. Cancer biology & therapy. vol 9. issue 6. 2010-09-10. PMID:20087061. |
we previously identified metal-responsive transcription factor-1 (mtf-1) as a positive contributor to mouse fibrosarcoma growth through effects on cell survival, proliferation, tumor angiogenesis and extracellular matrix remodeling. |
2010-09-10 |
2023-08-12 |
mouse |
| Barbara M Scher, Sucharita J Mistry, Nasreen S Haque, William Sche. Isolation and characterization of a large soluble form of fibronectin that stimulates adhesion, spreading, and alignment of mouse erythroleukemia cells. Experimental cell research. vol 316. issue 15. 2010-09-08. PMID:20547151. |
studies of this af should shed light on adhesion of cells to extracellular matrix molecules and on cell migration, both of which are critical in several biological processes such as wound healing, metastasis, matrix formation and structure, and organ development. |
2010-09-08 |
2023-08-12 |
mouse |
| Caroline Spiteri, Igal Raizman, Robert M Pilliar, Rita A Kande. Matrix accumulation by articular chondrocytes during mechanical stimulation is influenced by integrin-mediated cell spreading. Journal of biomedical materials research. Part A. vol 94. issue 1. 2010-08-17. PMID:20128012. |
thus, the objectives of this study were to determine the effect of compressive mechanical stimulation on cell shape and the role of integrins and mt1-mmp in mediating these changes and influencing matrix accumulation. |
2010-08-17 |
2023-08-12 |
cattle |
| John A Stella, Antonio D'Amore, William R Wagner, Michael S Sack. On the biomechanical function of scaffolds for engineering load-bearing soft tissues. Acta biomaterialia. vol 6. issue 7. 2010-08-16. PMID:20060509. |
the current state of the art in biomaterial processing enables a degree of controllable microstructure that can be used for the development of model systems to deduce fundamental biological implications of matrix morphologies on cell function. |
2010-08-16 |
2023-08-12 |
Not clear |
| Yona Nadir, Benjamin Brenne. Heparanase procoagulant effects and inhibition by heparins. Thrombosis research. vol 125 Suppl 2. 2010-08-11. PMID:20434010. |
heparanase is an endo-beta-d-glucuronidase capable of cleaving heparan sulfate (hs) side chains of heparan sulfate proteoglycans (hspg) on cell surfaces and the extracellular matrix, activity that is strongly implicated in tumor metastasis and angiogenesis. |
2010-08-11 |
2023-08-12 |
mouse |
| Noor Huda Daud, Cho Sanda Aung, Amitha K Hewavitharana, Ashley S Wilkinson, Jean-Thomas Pierson, Sarah J Roberts-Thomson, P Nicholas Shaw, Gregory R Monteith, Michael J Gidley, Marie-Odile Para. Mango extracts and the mango component mangiferin promote endothelial cell migration. Journal of agricultural and food chemistry. vol 58. issue 8. 2010-07-26. PMID:20349963. |
the promigratory effect of mango extracts or mangiferin was unrelated to an effect on cell proliferation, and did not involve a change in the production of matrix metalloprotease-2 or -9 by the endothelial cells. |
2010-07-26 |
2023-08-12 |
cattle |
| Guo-You Zhang, Tao Cheng, Ming-Hua Zheng, Cheng-Gang Yi, Hua Pan, Zhi-Jie Li, Xing-Long Chen, Qing Yu, Liang-Fu Jiang, Fei-Ya Zhou, Xiao-Yang Li, Jing-Quan Yang, Ting-Gang Chu, Wei-Yang Ga. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist inhibits transforming growth factor-beta1 and matrix production in human dermal fibroblasts. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 63. issue 7. 2010-06-30. PMID:19617014. |
to investigate the effect of the ppar-gamma agonist troglitazone on cell growth and matrix production in human dermal fibroblasts (hdf), hdf were cultured and grown in a different concentration of troglitazone. |
2010-06-30 |
2023-08-12 |
human |
| Jeffrey John, Angela Throm Quinlan, Chiara Silvestri, Kristen Billia. Boundary stiffness regulates fibroblast behavior in collagen gels. Annals of biomedical engineering. vol 38. issue 3. 2010-06-30. PMID:20012205. |
in all cases, boundary stiffness has a strong influence on cell behavior, most notably eliciting higher basal tension and activated force (in response to kcl) and more pronounced remodeling of the collagen matrix at higher boundary stiffness levels. |
2010-06-30 |
2023-08-12 |
human |
| M Cucchiarini, S Schetting, E F Terwilliger, D Kohn, H Madr. rAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions. Gene therapy. vol 16. issue 11. 2010-06-29. PMID:19641531. |
effects of the treatment on cell proliferation and survival, extracellular matrix synthesis, and expression of the alpha-smooth muscle actin (alpha-sma) contractile marker were monitored using biochemical, immunohistochemical, histological, and histomorphometric analyses. |
2010-06-29 |
2023-08-12 |
human |
| Li-Yi Sun, Dean-Kuo Hsieh, Po-Cheng Lin, Hsien-Tai Chiu, Tzyy-Wen Chio. Pulsed electromagnetic fields accelerate proliferation and osteogenic gene expression in human bone marrow mesenchymal stem cells during osteogenic differentiation. Bioelectromagnetics. vol 31. issue 3. 2010-06-17. PMID:19866474. |
in this study, we examined the effect of pulsed electromagnetic fields (pemfs) on cell proliferation, alkaline phosphatase (alp) activity, mineralization of the extracellular matrix, and gene expression in bone marrow mesenchymal stem cells (bmmscs) during osteogenic differentiation. |
2010-06-17 |
2023-08-12 |
human |
| John A Pedersen, Seth Lichter, Melody A Swart. Cells in 3D matrices under interstitial flow: effects of extracellular matrix alignment on cell shear stress and drag forces. Journal of biomechanics. vol 43. issue 5. 2010-06-09. PMID:20006339. |
cells in 3d matrices under interstitial flow: effects of extracellular matrix alignment on cell shear stress and drag forces. |
2010-06-09 |
2023-08-12 |
Not clear |