| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natsuko Tanabe, Emi Ito-Kato, Naoto Suzuki, Atsushi Nakayama, Bunnai Ogiso, Masao Maeno, Koichi It. IL-1alpha affects mineralized nodule formation by rat osteoblasts. Life sciences. vol 75. issue 19. 2004-10-04. PMID:15350829. |
we examined the effect of il-1alpha on cell proliferation, alkaline phosphatase (alpase) activity, mineralized nodule formation, and the expression of extracellular matrix proteins in rat osteosarcoma cell lines. |
2004-10-04 |
2023-08-12 |
rat |
| b' H S Taskinen, S Ruohonen, M Jagodic, M Khademi, T Olsson, M R\\xc3\\xb6ytt\\xc3\\xa. Distinct expression of TGF-beta1 mRNA in the endo- and epineurium after nerve injury. Journal of neurotrauma. vol 21. issue 7. 2004-09-23. PMID:15307908.' |
tgf-beta is a multifunctional regulatory protein with important effects on cell proliferation and differentiation, immune reactivity and extracellular matrix (ecm). |
2004-09-23 |
2023-08-12 |
rat |
| Mohammed Akmal, Anil Kesani, Bobby Anand, Abhinav Singh, Mike Wiseman, Allen Goodshi. Effect of nicotine on spinal disc cells: a cellular mechanism for disc degeneration. Spine. vol 29. issue 5. 2004-08-31. PMID:15129075. |
: to evaluate the effects of nicotine on cell proliferation, extracellular matrix production, and viability of np cells in three-dimensional alginate constructs cultured in vitro. |
2004-08-31 |
2023-08-12 |
Not clear |
| L Postiglione, G Di Domenico, G Giordano-Lanza, P Ladogana, M Turano, C Castaldo, F Di Meglio, S Cocozza, S Montagnan. Effect of human granulocyte macrophage-colony stimulating factor on differentiation and apoptosis of the human osteosarcoma cell line SaOS-2. European journal of histochemistry : EJH. vol 47. issue 4. 2004-08-10. PMID:14706926. |
effects on cell differentiation were determined by ecm (extracellular matrix) mineralization, morphology of some typical mature osteoblast differentiation markers, such as osteopontin and sialoprotein ii (bsp-ii), and production of bone ecm components such as collagen i. |
2004-08-10 |
2023-08-12 |
human |
| Chunnuan Chen, Kathryn Chen, Shang-Tian Yan. Effects of three-dimensional culturing on osteosarcoma cells grown in a fibrous matrix: analyses of cell morphology, cell cycle, and apoptosis. Biotechnology progress. vol 19. issue 5. 2004-07-21. PMID:14524722. |
osteosarcoma cells were cultured in stirred tank bioreactors with either a fibrous matrix or nonporous microcarriers to study the environmental effects on cell growth, morphology, cell cycle, and apoptosis. |
2004-07-21 |
2023-08-12 |
Not clear |
| R Matthew Klein, Mingzhe Zheng, Anthony Ambesi, Livingston Van De Water, Paula J McKeown-Long. Stimulation of extracellular matrix remodeling by the first type III repeat in fibronectin. Journal of cell science. vol 116. issue Pt 22. 2004-06-08. PMID:14576359. |
these findings are consistent with a model in which the binding of iii1c to the extracellular matrix results in a conformational remodeling of the fibronectin matrix, which has both short- and long-term effects on cell physiology. |
2004-06-08 |
2023-08-12 |
human |
| Buket Aybar, Ayhan Bilir, Handan Akçakaya, Tasşkin Ceyha. Effects of tricalcium phosphate bone graft materials on primary cultures of osteoblast cells in vitro. Clinical oral implants research. vol 15. issue 1. 2004-04-20. PMID:14731185. |
the results demonstrate that tcp graft material has no adverse effect on cell count, viability and morphology, and this material provides a matrix that favors limited cell proliferation. |
2004-04-20 |
2023-08-12 |
rat |
| Jiale He, Linda G Bau. Presentation of galectin-1 by extracellular matrix triggers T cell death. The Journal of biological chemistry. vol 279. issue 6. 2004-04-01. PMID:14617626. |
t cell apoptosis can be initiated by a variety of triggers, including galectin-1, a soluble, secreted lectin that binds to oligosaccharide ligands on cell surface glycoproteins, or to oligosaccharide ligands on extracellular matrix glycoproteins in tissue stroma. |
2004-04-01 |
2023-08-12 |
Not clear |
| Cecilia C Furnus, Alberto Valcarcel, Fernando N Dulout, Ana Lía Errecald. The hyaluronic acid receptor (CD44) is expressed in bovine oocytes and early stage embryos. Theriogenology. vol 60. issue 9. 2004-03-16. PMID:14580646. |
hyaluronic acid (ha) is a high molecular weight polysaccharide found in the extracellular matrix of most animal tissues, that exerts a profound influence on cell behavior. |
2004-03-16 |
2023-08-12 |
mouse |
| Julie Lanthier, Richard R Desrosier. Protein L-isoaspartyl methyltransferase repairs abnormal aspartyl residues accumulated in vivo in type-I collagen and restores cell migration. Experimental cell research. vol 293. issue 1. 2004-03-11. PMID:14729060. |
in this study, we investigated the alteration of aspartyl residues in extracellular matrix (ecm) proteins, type-i collagen and fibronectin, and in integrin- and ecm-binding motifs during aging, as well as the resulting effects on cell biological functions such as migration and attachment. |
2004-03-11 |
2023-08-12 |
rat |
| J B Schüttert, M H Liu, N Gliem, G M Fiedler, S Zopf, C Mayer, G A Müller, R W Grunewal. Human renal fibroblasts derived from normal and fibrotic kidneys show differences in increase of extracellular matrix synthesis and cell proliferation upon angiotensin II exposure. Pflugers Archiv : European journal of physiology. vol 446. issue 3. 2004-03-05. PMID:12684791. |
we investigated the influence of ang ii on cell proliferation and synthesis of extracellular matrix (collagen i, iii and fibronectin) in human renal fibroblasts derived from normal (tk 173 cell line) and fibrotic (tk 188 cell line) kidneys which possess both ang ii type l and type 2 (at1 and at2) receptors. |
2004-03-05 |
2023-08-12 |
human |
| J B Schüttert, M H Liu, N Gliem, G M Fiedler, S Zopf, C Mayer, G A Müller, R W Grunewal. Human renal fibroblasts derived from normal and fibrotic kidneys show differences in increase of extracellular matrix synthesis and cell proliferation upon angiotensin II exposure. Pflugers Archiv : European journal of physiology. vol 446. issue 3. 2004-03-05. PMID:12684791. |
the ang ii mediated effect on cell proliferation and extracellular matrix synthesis was diminished in the presence of the at1 receptor blocker losartan in both cell lines. |
2004-03-05 |
2023-08-12 |
human |
| Karine Hellemans, Peggy Verbuyst, Erik Quartier, Frans Schuit, Krista Rombouts, Ross A S Chandraratna, Detlef Schuppan, Albert Geert. Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids. Hepatology (Baltimore, Md.). vol 39. issue 1. 2004-03-04. PMID:14752828. |
retinoic acids, rar, and rxr selective agonists and an rar antagonist were used to evaluate the effects of retinoid signalling on matrix synthesis by northern blotting and immunoprecipitation, and on cell proliferation by brdu incorporation. |
2004-03-04 |
2023-08-12 |
rat |
| Sajjad Razaq, Robert J Wilkins, Jill P G Urba. The effect of extracellular pH on matrix turnover by cells of the bovine nucleus pulposus. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 12. issue 4. 2004-01-21. PMID:12883962. |
the results showed that acid conditions had a profound effect on cell matrix turnover; at ph 6.4, total production of most species measured was inhibited by more than 50% compared to production at ph 7.2; production of sulphated gags and of timp-1 fell by >90%. |
2004-01-21 |
2023-08-12 |
cattle |
| Andrzej Chciałowsk. [The importance of inhibition of adhesion molecules in allergic inflammation]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 14. issue 84. 2004-01-14. PMID:14524255. |
these molecules are glycoprotein particles present on cell surface and on intracellular matrix proteins. |
2004-01-14 |
2023-08-12 |
Not clear |
| Satoko Nakajima, Tetsuji Tanaka, Naohiko Umesaki, Osamu Ishik. Leukemia inhibitory factor regulates cell survival of normal human endometrial stromal cells. International journal of molecular medicine. vol 11. issue 3. 2004-01-13. PMID:12579339. |
further, the extracellular matrix did not affect these stimulatory effects of lif on cell viability of 8-br-camp-stimulated endometrial stromal cells. |
2004-01-13 |
2023-08-12 |
human |
| J A Keelan, M Blumenstein, R J A Helliwell, T A Sato, K W Marvin, M D Mitchel. Cytokines, prostaglandins and parturition--a review. Placenta. vol 24 Suppl A. 2004-01-05. PMID:12842412. |
prostaglandins, released by the membranes in response to stretch and the actions of pro-inflammatory cytokines, act not only upon the myometrium and cervix, but may also exert paracrine/autocrine effects on cell viability and matrix protein integrity. |
2004-01-05 |
2023-08-12 |
Not clear |
| Alan A Woods, Michael J Davie. Fragmentation of extracellular matrix by hypochlorous acid. The Biochemical journal. vol 376. issue Pt 1. 2003-12-09. PMID:12911330. |
the effect of such matrix modifications on cellular behaviour is poorly understood, though it is known that changes in matrix materials can have profound effects on cell adhesion, proliferation, growth and phenotype. |
2003-12-09 |
2023-08-12 |
Not clear |
| Jin Woo Lee, Yun Hee Kim, Hee Boong Park, Li-Hui Xu, William G Cance, Joel A Block, Sean P Scull. The C-terminal domain of focal adhesion kinase reduces the tumor cell invasiveness in chondrosarcoma cell lines. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 21. issue 6. 2003-11-18. PMID:14554221. |
in the current manuscript we examine the effect of fak inhibition on cell attachment to extracellular matrix (ecm) and in vitro invasion. |
2003-11-18 |
2023-08-12 |
human |
| Bo Hu, Shuhui Wang, Yingze Zhang, Carol A Feghali, Jeffrey R Dingman, Timothy M Wrigh. A nuclear target for interleukin-1alpha: interaction with the growth suppressor necdin modulates proliferation and collagen expression. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 17. 2003-10-29. PMID:12913118. |
based on these findings, we propose that the constitutively up-regulated expression of pre-il-1 alpha in the nuclei of ssc fibroblasts up-regulates proliferation and matrix production of ssc fibroblasts through binding necdin, and by counteracting its effects on cell growth and collagen production. |
2003-10-29 |
2023-08-12 |
Not clear |