| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Emonard, C Munaut, M Melin, H Lortat-Jacob, J A Grimau. Interleukin-6 does not regulate interstitial collagenase, stromelysin and tissue inhibitor of metalloproteinases synthesis by cultured human fibroblasts. Matrix (Stuttgart, Germany). vol 12. issue 6. 1993-03-15. PMID:1287415. |
these results strongly suggest that il-6 is not involved in the extracellular matrix breakdown, either directly by acting on cell production of mmps or timp, or indirectly by modulating the effect of il-1 on the synthesis of mmps and timp. |
1993-03-15 |
2023-08-11 |
human |
| S C Evans, L C Lopez, B D Shu. Dominant negative mutation in cell surface beta 1,4-galactosyltransferase inhibits cell-cell and cell-matrix interactions. The Journal of cell biology. vol 120. issue 4. 1993-03-15. PMID:8432725. |
in control assays, inducing the tlgt protein had no effect on cell interactions with fibronectin (which is independent of galtase), or on the cytoskeleton attachment of another matrix receptor (beta 1 integrin), or on overall glycoprotein synthesis, thus eliminating nonspecific effects of the tlgt protein on cellular adhesion and metabolism. |
1993-03-15 |
2023-08-12 |
Not clear |
| S Eisenberg, E Sehayek, T Olivecrona, I Vlodavsk. Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. The Journal of clinical investigation. vol 90. issue 5. 1992-12-22. PMID:1430223. |
lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. |
1992-12-22 |
2023-08-11 |
human |
| L Ramsden, C C Ride. Selective and differential binding of interleukin (IL)-1 alpha, IL-1 beta, IL-2 and IL-6 to glycosaminoglycans. European journal of immunology. vol 22. issue 11. 1992-12-08. PMID:1425926. |
these findings suggest that during the immune response, interleukins will tend to be retained at sites of secretion by interaction with glycosaminoglycans in the extracellular matrix and on cell surfaces. |
1992-12-08 |
2023-08-11 |
Not clear |
| S S McCachren, V A Lightne. Expression of human tenascin in synovitis and its regulation by interleukin-1. Arthritis and rheumatism. vol 35. issue 10. 1992-11-06. PMID:1384510. |
tenascin is an extracellular matrix glycoprotein with effects on cell adhesion, cell migration, and lymphocyte activation. |
1992-11-06 |
2023-08-11 |
human |
| C T Basson, O Kocher, M D Basson, A Asis, J A Madr. Differential modulation of vascular cell integrin and extracellular matrix expression in vitro by TGF-beta 1 correlates with reciprocal effects on cell migration. Journal of cellular physiology. vol 153. issue 1. 1992-10-15. PMID:1522126. |
differential modulation of vascular cell integrin and extracellular matrix expression in vitro by tgf-beta 1 correlates with reciprocal effects on cell migration. |
1992-10-15 |
2023-08-11 |
Not clear |
| J Sandström, L Carlsson, S L Marklund, T Edlun. The heparin-binding domain of extracellular superoxide dismutase C and formation of variants with reduced heparin affinity. The Journal of biological chemistry. vol 267. issue 25. 1992-10-07. PMID:1517248. |
a fundamental property of the secretory tetrameric extracellular superoxide dismutase (ec-sod) is its affinity for heparin and analogues, in vivo, mediating attachment to heparan sulfate proteoglycans located on cell surfaces and in the connective tissue matrix. |
1992-10-07 |
2023-08-11 |
Not clear |
| M J Somerman, B Shroff, R A Foster, W T Butler, J J Sau. Mineral-associated adhesion proteins are linked to root formation. Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia. vol 88 Suppl 1. 1992-09-23. PMID:1508903. |
thus, significant research efforts have focused on understanding the effects of extracellular matrix proteins on cell function. |
1992-09-23 |
2023-08-11 |
mouse |
| M F Young, J M Kerr, K Ibaraki, A M Heegaard, P G Robe. Structure, expression, and regulation of the major noncollagenous matrix proteins of bone. Clinical orthopaedics and related research. issue 281. 1992-09-14. PMID:1499220. |
the noncollagenous proteins (ncps) that predominate the bone matrix have recently been the focus of intense investigation because of their potential influence on cell attachment, ca2+ and hydroxyapatite binding, and the mineralization of bone tissue. |
1992-09-14 |
2023-08-11 |
Not clear |
| J Hagège, M N Peraldi, E Rondeau, C Adida, F Delarue, R Medcalf, W D Schleuning, J D Srae. Plasminogen activator inhibitor-1 deposition in the extracellular matrix of cultured human mesangial cells. The American journal of pathology. vol 141. issue 1. 1992-08-18. PMID:1632457. |
we demonstrate that pai-1 is a major component of the extracellular matrix of cultured human mesangial cells, where its deposition is dependent on cell density. |
1992-08-18 |
2023-08-11 |
human |
| K V Honn, Y Q Chen, J Timar, J M Onoda, J S Hatfield, S E Fligiel, B W Steinert, C A Diglio, I M Grossi, K K Nelso. Alpha IIb beta 3 integrin expression and function in subpopulations of murine tumors. Experimental cell research. vol 201. issue 1. 1992-07-24. PMID:1377132. |
comparison of the amount of alpha iib beta 3 receptor expressed on cell surface with tumor cell ability to induce platelet aggregation (tcipa) and to adhere to fibronectin or subendothelial matrix revealed a positive correlation. |
1992-07-24 |
2023-08-11 |
Not clear |
| M H Barcellos-Hof. Mammary epithelial reorganization on extracellular matrix is mediated by cell surface galactosyltransferase. Experimental cell research. vol 201. issue 1. 1992-07-24. PMID:1612125. |
alpha-la present from the beginning of culture on reconstituted matrix had no effect on cell attachment but caused concentration-dependent inhibition of the first two steps of reorganization, i.e., cell elongation and network formation, which then interfered with subsequent events. |
1992-07-24 |
2023-08-11 |
Not clear |
| E G Schuet. Extracellular matrix regulation of hepatic transcription factors is dependent on cell structure. Hepatology (Baltimore, Md.). vol 15. issue 6. 1992-06-26. PMID:1592358. |
extracellular matrix regulation of hepatic transcription factors is dependent on cell structure. |
1992-06-26 |
2023-08-11 |
Not clear |
| S Adle. Integrin receptors in the glomerulus: potential role in glomerular injury. The American journal of physiology. vol 262. issue 5 Pt 2. 1992-06-24. PMID:1590413. |
the extracellular matrix (ecm) exerts important effects on cell function that play a vital role in such diverse processes as embryogenesis, wound healing, cancer metastasis, and inflammation. |
1992-06-24 |
2023-08-11 |
Not clear |
| W Casscell. Smooth muscle cell growth factors. Progress in growth factor research. vol 3. issue 3. 1992-06-11. PMID:1811790. |
further insights are apt to come from the increasing recognition that growth factors have other effects--on cell attachment, migration, survival, production of extracellular matrix, thrombosis, vaso-constriction, regulation of cytokine synthesis, and inhibition of growth. |
1992-06-11 |
2023-08-11 |
mouse |
| S I Galkina, G F Sud'Ina, L B Margoli. Cell-cell contacts alter intracellular pH. Experimental cell research. vol 200. issue 1. 1992-05-18. PMID:1563489. |
dependence of ph(i) on cell density could be simulated by different concentration of arg-gly-asp--which is part of the site of extracellular matrix proteins involved in integrin binding. |
1992-05-18 |
2023-08-11 |
Not clear |
| L L Hilenski, X H Ma, N Vinson, L Terracio, T K Bor. The role of beta 1 integrin in spreading and myofibrillogenesis in neonatal rat cardiomyocytes in vitro. Cell motility and the cytoskeleton. vol 21. issue 2. 1992-05-12. PMID:1373110. |
the influence of the extracellular matrix (ecm) on cell behavior, myofibrillogenesis and cytoarchitecture was investigated in neonatal rat cardiac myocytes in vitro. |
1992-05-12 |
2023-08-11 |
rat |
| D J Whitby, M W Ferguso. The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development (Cambridge, England). vol 112. issue 2. 1992-04-09. PMID:1724421. |
the cellular mechanisms underlying these differing forms of wound healing are unknown but the extracellular matrix (ecm), through its effects on cell function, may play a key role. |
1992-04-09 |
2023-08-11 |
mouse |
| T Gray, J Rundhaug, P Netteshei. Critical variables controlling cell proliferation in primary cultures of rat tracheal epithelial cells. In vitro cellular & developmental biology : journal of the Tissue Culture Association. vol 27A. issue 10. 1992-01-06. PMID:1960148. |
coating the dishes with extracellular matrix components had little effect on cell attachment or colony forming efficiency (cfe). |
1992-01-06 |
2023-08-11 |
rat |
| L J Kornberg, H S Earp, C E Turner, C Prockop, R L Julian. Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 19. 1991-10-31. PMID:1717976. |
because the extracellular matrix has profound influences on cell behavior, it seems likely that integrins transduce biochemical signals across the cell membrane. |
1991-10-31 |
2023-08-11 |
human |