| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kentaro Ide, Sanai Takahashi, Keiko Sakai, Yuki Taga, Tomonori Ueno, David Dickens, Rosalind Jenkins, Francesco Falciani, Takako Sasaki, Kazuhiro Ooi, Shuichi Kawashiri, Kazunori Mizuno, Shunji Hattori, Takao Saka. The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells. The Journal of biological chemistry. vol 297. issue 1. 2021-08-24. PMID:34029590. |
in addition, pro-hyp has profound effects on cell proliferation, with significantly upregulated extracellular signal-regulated kinase phosphorylation and extracellular matrix production and increased type i collagen network organization. |
2021-08-24 |
2023-08-13 |
mouse |
| Nadia Garibaldi, Barbara M Contento, Gabriele Babini, Jacopo Morini, Stella Siciliani, Marco Biggiogera, Mario Raspanti, Joan C Marini, Antonio Rossi, Antonella Forlino, Roberta Besi. Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta. Matrix biology : journal of the International Society for Matrix Biology. vol 98. 2021-08-12. PMID:33798677. |
therefore, the effect of the chemical chaperone 4-phenylbutyrate (4-pba) on cell homeostasis, collagen trafficking, matrix production and mineralization was investigated in primary osteoblasts from two murine models of moderate oi, col1a1 |
2021-08-12 |
2023-08-13 |
Not clear |
| Lenin Proaño, Raissa Borges Curtarelli, Mariane Beatriz Sordi, Izabella Thaís Silva, Gislaine Fongaro, Márcio Côrrea, Marco Aurélio Bianchini, Ariadne Cristiane Cabral Cru. Increasing the Thickness of the Collagen Xenogeneic Matrix Prevents Early Matrix Degradation and Improves the Proliferation, Adhesion, and Viability of Human Gingival Fibroblasts and Mesenchymal Stem Cells. The International journal of periodontics & restorative dentistry. vol 41. issue 4. 2021-08-03. PMID:34328477. |
this in vitro study evaluated the influence of xenogeneic collagen matrix thickness on cell adhesion, morphology, viability, proliferation, and matrix degradation. |
2021-08-03 |
2023-08-13 |
human |
| Bryan Falcones, Héctor Sanz-Fraile, Esther Marhuenda, Irene Mendizábal, Ignacio Cabrera-Aguilera, Nanthilde Malandain, Juan J Uriarte, Isaac Almendros, Daniel Navajas, Daniel J Weiss, Ramon Farré, Jorge Oter. Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells. Polymers. vol 13. issue 14. 2021-07-29. PMID:34301107. |
we here propose a strategy for improving the therapeutic efficacy of mscs based on cell preconditioning by growing them in native extracellular matrix (ecm) derived from the lung. |
2021-07-29 |
2023-08-13 |
Not clear |
| Joseph d'Alessandro, Alex Barbier-Chebbah, Victor Cellerin, Olivier Benichou, René Marc Mège, Raphaël Voituriez, Benoît Ladou. Cell migration guided by long-lived spatial memory. Nature communications. vol 12. issue 1. 2021-07-26. PMID:34226542. |
while it is established that cells can modify their environment by depositing biochemical signals or mechanically remodelling the extracellular matrix, the impact of such self-induced environmental perturbations on cell trajectories at various scales remains unexplored. |
2021-07-26 |
2023-08-13 |
Not clear |
| Zahra Gounani, Didem Şen Karaman, Arun P Venu, Fang Cheng, Jessica M Rosenhol. Coculture of P. aeruginosa and S. aureus on cell derived matrix - An in vitro model of biofilms in infected wounds. Journal of microbiological methods. vol 175. 2021-07-21. PMID:32593628. |
coculture of p. aeruginosa and s. aureus on cell derived matrix - an in vitro model of biofilms in infected wounds. |
2021-07-21 |
2023-08-13 |
cattle |
| Jesper Bergwik, Amanda Kristiansson, Jörgen Larsson, Simon Ekström, Bo Åkerström, Maria Allhor. Binding of the human antioxidation protein α Redox biology. vol 41. 2021-07-05. PMID:33607500. |
heparin is found mainly in mast cells, while heparan sulfate is found in connective tissue, extracellular matrix and on cell membranes in most tissues. |
2021-07-05 |
2023-08-13 |
human |
| Gerald Schwerdt, Michael Kopf, Michael Gekl. The Impact of the Nephrotoxin Ochratoxin A on Human Renal Cells Studied by a Novel Co-Culture Model Is Influenced by the Presence of Fibroblasts. Toxins. vol 13. issue 3. 2021-06-30. PMID:33803529. |
we studied the effect of ota on cell survival, the expression of genes and/or proteins related to cell death, extracellular matrix and energy homeostasis. |
2021-06-30 |
2023-08-13 |
human |
| Ana M Reyes-Ramos, Yasmín R Álvarez-García, Natalia Solodin, Jorge Almodovar, Elaine T Alarid, Wandaliz Torres-Garcia, Maribella Domenec. Collagen I Fibrous Substrates Modulate the Proliferation and Secretome of Estrogen Receptor-Positive Breast Tumor Cells in a Hormone-Restricted Microenvironment. ACS biomaterials science & engineering. vol 7. issue 6. 2021-06-21. PMID:33688723. |
in this study, the impact of a type i collagen matrix orientation and fibrous architecture on cell proliferation and response to estrogen receptor (er) therapy were examined using estrogen-dependent breast tumor cells (mcf-7 and t-47d) cultured in a hormone-restricted environment. |
2021-06-21 |
2023-08-13 |
Not clear |
| Martina Muck, Benedikt Wolfsjäger, Karoline Seibert, Christian Maier, Shaukat Ali Lone, Achim Walter Hassel, Werner Baumgartner, Johannes Heit. Femtosecond Laser-Processing of Pre-Anodized Ti-Based Bone Implants for Cell-Repellent Functionalization. Nanomaterials (Basel, Switzerland). vol 11. issue 5. 2021-06-05. PMID:34065199. |
while earlier experiments with fibroblasts had shown that femtosecond laser-processing followed by electrochemical anodization had a significant impact on cell adhesion reduction, for osteoblasts the same conditions resulted in an activation of the cells with increased production of extracellular matrix material. |
2021-06-05 |
2023-08-13 |
human |
| Jun Zhu, Qiwei Fu, Jiahua Shao, Jinhui Peng, Qirong Qian, Yiqin Zhou, Yi Che. Over-expression of MEG3 promotes differentiation of bone marrow mesenchymal stem cells into chondrocytes by regulating miR-129-5p/RUNX1 axis. Cell cycle (Georgetown, Tex.). vol 20. issue 1. 2021-06-03. PMID:33410373. |
we investigated the effects of over-expression and knockdown of meg3 on cell viability, cell differentiation, and the expressions of meg3, mir-129-5p, col2, chondrocyte differentiation-related genes (sry-type high-mobility-group box 9 (sox9), sox5, aggrecan, silent information regulator 1 (sirt1), and cartilage oligomeric matrix protein (comp)). |
2021-06-03 |
2023-08-13 |
Not clear |
| Weidong Zhang, Genglei Chu, Huan Wang, Song Chen, Bin Li, Fengxuan Ha. Effects of Matrix Stiffness on the Differentiation of Multipotent Stem Cells. Current stem cell research & therapy. vol 15. issue 5. 2021-05-27. PMID:32268870. |
in addition, as stiffness-mediated cell differentiation may be affected by other factors, the combined effects of matrix stiffness and viscoelasticity, surface topography, chemical composition, and external mechanical stimuli on cell differentiation are also summarized. |
2021-05-27 |
2023-08-13 |
Not clear |
| Jinfu Chen, Junjun Zhu, Tianfei Zhu, Jiaming Cui, Zhenhan Deng, Kang Chen, Chongfei Chang, Yiyun Geng, Fei Chen, Kan Ouyang, Jianyi Xiong, Manyi Wang, Daping Wang, Weimin Zh. Pathological changes of frozen shoulder in rat model and the therapeutic effect of PPAR-γ agonist. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 39. issue 4. 2021-05-17. PMID:33222263. |
in the study, the effect of ppar-γ agonist cddo-im treatment on cell proliferation, migration, and extracellular matrix proteins synthesis (vimentin, α-smooth muscle actin, collagen i, and collagen iii) were tested by cell proliferation test, scratches test, real-time quantitative polymerase chain reaction, and western blot analysis. |
2021-05-17 |
2023-08-13 |
rat |
| A A Malik, B Wennberg, P Gerle. The Impact of Elastic Deformations of the Extracellular Matrix on Cell Migration. Bulletin of mathematical biology. vol 82. issue 4. 2021-05-14. PMID:32248312. |
the impact of elastic deformations of the extracellular matrix on cell migration. |
2021-05-14 |
2023-08-13 |
human |
| Ronald G Ireland, Mark Kibschull, Julie Audet, Maya Ezzo, Boris Hinz, Stephen J Lye, Craig A Simmon. Combinatorial extracellular matrix microarray identifies novel bioengineered substrates for xeno-free culture of human pluripotent stem cells. Biomaterials. vol 248. 2021-05-14. PMID:32283392. |
to address this need, we developed an extracellular matrix (ecm) microarray screening platform capable of tightly controlling substrate stiffness and ecm protein composition to screen the effects of these cues and their interactions on cell fate. |
2021-05-14 |
2023-08-13 |
human |
| Harshita Arora, Nan Shang, Khushwant S Bhullar, Jianping W. Pea protein-derived tripeptide LRW shows osteoblastic activity on MC3T3-E1 cells via the activation of the Akt/Runx2 pathway. Food & function. vol 11. issue 8. 2021-05-14. PMID:32756709. |
furthermore, tripeptide lrw increased matrix mineralization as evidenced by alizarin-s red staining and nodule formation, osteoprotegerin levels (opg; 2-fold increase), and wound healing based on cell migration assay. |
2021-05-14 |
2023-08-13 |
Not clear |
| Rúben F Pereira, Bianca N Lourenço, Paulo J Bártolo, Pedro L Granj. Bioprinting a Multifunctional Bioink to Engineer Clickable 3D Cellular Niches with Tunable Matrix Microenvironmental Cues. Advanced healthcare materials. vol 10. issue 2. 2021-05-14. PMID:33135399. |
bioprinted cell-adhesive and protease-degradable hydrogels modulate cell proliferation and ecm deposition in a matrix-stiffness dependent manner over 14 days of culture regardless of cell spreading, demonstrating the ability to probe the effect of matrix cues on cell response. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yuanbo Jia, Yanzhong Wang, Lele Niu, Hang Zhang, Jin Tian, Dengfeng Gao, Xiaohui Zhang, Tian Jian Lu, Jin Qian, Guoyou Huang, Feng X. The Plasticity of Nanofibrous Matrix Regulates Fibroblast Activation in Fibrosis. Advanced healthcare materials. vol 10. issue 8. 2021-05-14. PMID:33511795. |
the effect of ecm elasticity on cell behaviors has been extensively investigated, while less attention has been paid to the effect of matrix fiber-network plasticity at microscale, although plastic remodeling of fibrous matrix is a common phenomenon in fibrosis. |
2021-05-14 |
2023-08-13 |
Not clear |
| Akram Shafiee, Mousa Kehtari, Zeinab Zarei, Masoud Soleimani, Reyhaneh Varshochian, Amirhossein Ahmadi, Fatemeh Atyabi, Rassoul Dinarvan. An in situ hydrogel-forming scaffold loaded by PLGA microspheres containing carbon nanotube as a suitable niche for neural differentiation. Materials science & engineering. C, Materials for biological applications. vol 120. 2021-05-14. PMID:33545882. |
the cell-extracellular matrix (ecm) interactions are known to have a strong impact on cell behaviors in neural tissues. |
2021-05-14 |
2023-08-13 |
Not clear |
| Ilia Platzman, Christine Anna Muth, Cornelia Lee-Thedieck, Diego Pallarola, Ralitsa Atanasova, Ilia Louban, Eva Altrock, Joachim P Spat. Surface Properties of Nanostructured Bio-Active Interfaces: Impacts of Surface Stiffness and Topography on Cell-Surface Interactions. RSC advances. vol 3. issue 32. 2021-05-11. PMID:33791090. |
due to their ability to confer key functions of the native extracellular matrix (ecm) poly(ethylene glycol) (peg)-based and peg-modified materials have been extensively used as biocompatible and biofunctionalized substrate systems to study the influence of environmental parameters on cell adhesion |
2021-05-11 |
2023-08-13 |
Not clear |