| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
at the molecular level, we largely replicated the es effects, such as reduced serotonin transporter (sert) expression in the amygdala and increased norepinephrine transporter (net) expression in the medial prefrontal cortex (mpfc) and hippocampus. |
2024-02-09 |
2024-02-12 |
mouse |
| Sophia Armand, Christelle Langley, Annette Johansen, Brice Ozenne, Oliver Overgaard-Hansen, Kristian Larsen, Peter Steen Jensen, Gitte Moos Knudsen, Barbara Jacquelyn Sahakian, Dea Siggard Stenbæk, Patrick MacDonald Fishe. Functional brain responses to emotional faces after three to five weeks of intake of escitalopram in healthy individuals: a double-blind, placebo-controlled randomised study. Scientific reports. vol 14. issue 1. 2024-02-07. PMID:38326352. |
short-term intake of selective serotonin reuptake inhibitors (ssris) modulates threat-related amygdala responses in healthy individuals. |
2024-02-07 |
2024-02-10 |
Not clear |
| Vanessa K Tassone, Fatemeh Gholamali Nezhad, Ilya Demchenko, Alice Rueda, Venkat Bha. Amygdala biomarkers of treatment response in major depressive disorder: An fMRI systematic review of SSRI antidepressants. Psychiatry research. Neuroimaging. vol 338. 2024-01-06. PMID:38183847. |
functional neuroimaging studies have demonstrated abnormal activity and functional connectivity (fc) of the amygdala among individuals with major depressive disorder (mdd), which may be rectified with selective serotonin reuptake inhibitor (ssri) treatment. |
2024-01-06 |
2024-01-09 |
Not clear |
| Alberto Fernández-Teruel, Toni Cañete, Daniel Sampedro-Viana, Ignasi Oliveras, Rafael Torrubia, Adolf Tobeñ. Contribution of the Roman rat lines/strains to personality neuroscience: neurobehavioral modeling of internalizing/externalizing psychopathologies. Personality neuroscience. vol 6. 2023-12-19. PMID:38107777. |
for example, relative to rla rats, rhas exhibit decreased function of the prefrontal cortex (pfc), hippocampus and amygdala, increased functional tone of the mesolimbic dopamine system, a deficit of central metabotropic glutamate-2 (mglu2) receptors, increased density of serotonin 5-ht2a receptors in the pfc, impairment of gabaergic transmission in the pfc, alterations of several synaptic markers and increased density of pyramidal immature dendrític spines in the pfc. |
2023-12-19 |
2023-12-21 |
rat |
| Kaito Kurogi, Fuka Taniguchi, Ryohei Matsuo, Marina Shinozuka, Raiki Suzaki, Shinobu Yasu. Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion. European journal of pharmacology. 2023-10-20. PMID:37858834. |
in mice housed in large cages, sex-specific dysregulation of brain monoamine systems was observed; dopamine turnover to homovanillic acid or norepinephrine in the prefrontal cortex was elevated in males, while serotonin turnover to 5-hydroxyindoleacetic acid in the amygdala was increased in females. |
2023-10-20 |
2023-11-08 |
mouse |
| Shubham Ghuge, Ziaur Rahman, Nagesh Bhale, Amol G Dikundwar, Manoj P Dandeka. Multistrain probiotic rescinds quinpirole-induced obsessive-compulsive disorder phenotypes by reshaping of microbiota gut-brain axis in rats. Pharmacology, biochemistry, and behavior. 2023-10-07. PMID:37804865. |
our probiotic formulation also prevented the elevated mrna expression of interleukin-6, tumor-necrosis factor-α, and c-reactive protein in the amygdala and dysregulated levels of 5-hydroxytryptamine, dopamine, and noradrenaline in the frontal cortex of quinpirole-injected rats. |
2023-10-07 |
2023-10-15 |
rat |
| Emi Hasegawa, Yulong Li, Takeshi Sakura. Regulation of REM Sleep in Mice: The Role of Dopamine and Serotonin Function in the Basolateral Amygdala. Neuroscience research. 2023-09-11. PMID:37696450. |
regulation of rem sleep in mice: the role of dopamine and serotonin function in the basolateral amygdala. |
2023-09-11 |
2023-10-07 |
mouse |
| Yi Jiang, Jie Zhou, Bai-Lin Song, Yan Wang, Dong-Lin Zhang, Zheng-Tian Zhang, Lai-Fu Li, Ying-Juan Li. 5-HT1A receptor in the central amygdala and 5-HT2A receptor in the basolateral amygdala are involved in social hierarchy in male mice. European journal of pharmacology. 2023-09-02. PMID:37659688. |
5-ht receptors are abundantly expressed in the amygdala, which is considered as the central node for the perception and learning of social hierarchy. |
2023-09-02 |
2023-09-07 |
mouse |
| Yi Jiang, Jie Zhou, Bai-Lin Song, Yan Wang, Dong-Lin Zhang, Zheng-Tian Zhang, Lai-Fu Li, Ying-Juan Li. 5-HT1A receptor in the central amygdala and 5-HT2A receptor in the basolateral amygdala are involved in social hierarchy in male mice. European journal of pharmacology. 2023-09-02. PMID:37659688. |
after the tube test, the amygdala and 5-ht neurons in the dorsal raphe nucleus were activated in lower-rank individuals. |
2023-09-02 |
2023-09-07 |
mouse |
| Yi Jiang, Jie Zhou, Bai-Lin Song, Yan Wang, Dong-Lin Zhang, Zheng-Tian Zhang, Lai-Fu Li, Ying-Juan Li. 5-HT1A receptor in the central amygdala and 5-HT2A receptor in the basolateral amygdala are involved in social hierarchy in male mice. European journal of pharmacology. 2023-09-02. PMID:37659688. |
our findings provide novel insights into the divergent functions of 5-ht receptors in the amygdala related to social hierarchy, which is closely related to our health and welfare. |
2023-09-02 |
2023-09-07 |
mouse |
| Francesco Tortora, Abed L Hadipour, Simone Battaglia, Alessandra Falzone, Alessio Avenanti, Carmelo M Vicari. The Role of Serotonin in Fear Learning and Memory: A Systematic Review of Human Studies. Brain sciences. vol 13. issue 8. 2023-08-26. PMID:37626553. |
accumulating evidence from both animal and human studies suggests that brain regions involved in fc, such as the amygdala, hippocampus, and prefrontal cortex, possess a high density of 5-ht receptors, implicating the crucial involvement of serotonin in aversive learning. |
2023-08-26 |
2023-09-07 |
human |
| Rebecca Ravenelle, Carolina Fernandes-Henriques, Jinah Lee, Jia Liu, Ekaterina Likhtik, Nesha S Burghard. Serotonergic Modulation of the BNST-CeA Circuit Promotes Sex Differences in Fear Learning. bioRxiv : the preprint server for biology. 2023-07-18. PMID:37461483. |
here, we show that serotonin differentially affects fear learning and communication in the extended amygdala of male and female mice. |
2023-07-18 |
2023-08-14 |
mouse |
| Aleeza Sunderji, Heather D Gallant, Alexander Hall, Andrew D Davis, Irina Pokhvisneva, Michael J Meaney, Patricia P Silveira, Roberto B Sassi, Geoffrey B Hal. Serotonin transporter (5-HTT) gene network moderates the impact of prenatal maternal adversity on orbitofrontal cortical thickness in middle childhood. PloS one. vol 18. issue 6. 2023-06-15. PMID:37319261. |
here, we investigate whether the function of a network of genes co-expressed with the serotonin transporter in the amygdala moderates the impact of prenatal maternal adversity on the structure of the orbitofrontal cortex (ofc) in middle childhood and/or the degree of temperamental inhibition exhibited in toddlerhood. |
2023-06-15 |
2023-08-14 |
Not clear |
| Aleeza Sunderji, Heather D Gallant, Alexander Hall, Andrew D Davis, Irina Pokhvisneva, Michael J Meaney, Patricia P Silveira, Roberto B Sassi, Geoffrey B Hal. Serotonin transporter (5-HTT) gene network moderates the impact of prenatal maternal adversity on orbitofrontal cortical thickness in middle childhood. PloS one. vol 18. issue 6. 2023-06-15. PMID:37319261. |
our results indicate that in the presence of a low functioning serotonin transporter gene network in the amygdala, higher levels of prenatal adversity are associated with greater right ofc thickness at 6-12 years old. |
2023-06-15 |
2023-08-14 |
Not clear |
| Nina Colombel, Guillaume Ferreira, Regina M Sullivan, Gérard Coureau. Dynamic developmental changes in neurotransmitters supporting infant attachment learning. Neuroscience and biobehavioral reviews. 2023-05-31. PMID:37257712. |
here we review the neural circuitry supporting this neonatal odor learning, unique compared to adults, focusing specifically on the early roles of neurotransmitters such as glutamate, gaba (gamma-aminobutyric acid), serotonin, dopamine and norepinephrine, in the olfactory bulb, the anterior piriform cortex and amygdala. |
2023-05-31 |
2023-08-14 |
Not clear |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). |
2023-05-30 |
2023-08-14 |
Not clear |
| Guoyi Tang, Yuan Guo, Li Zhang, Tao Wang, Ruotong Li, Jie Yang, Yixuan Wang, Jian Li. 5-HT Behavioural brain research. 2023-05-11. PMID:37169129. |
5-ht parkinson's disease (pd) is commonly accompanied with anxiety, multiple studies indicate that the basolateral amygdaloid nucleus (bla) is closely related to modulation of anxiety and expresses serotonin |
2023-05-11 |
2023-08-14 |
Not clear |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
we examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of neurotransmitters, including dopamine, serotonin, glutamate, glutamine, and gaba in the amygdala and hippocampus. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
dopamine, serotonin, glutamate, glutamine, and gaba were extracted from both the amygdala and hippocampus and were separated and quantified using a developed and validated hplc-ms/ms method. |
2023-04-28 |
2023-08-14 |
rat |