All Relations between ca1 field and serotonin

Reference Sentence Publish Date Extraction Date Species
Q Pei, L Lewis, M E Sprakes, E J Jones, D G Grahame-Smith, T S Zetterstr\\xc3\\xb6. Serotonergic regulation of mRNA expression of Arc, an immediate early gene selectively localized at neuronal dendrites. Neuropharmacology vol 39 issue 3 2000 10698012 Additional 5-HT receptors as well as other neurotransmitters may also be involved, particularly in the striatum and in CA1 subfield of the hippocampus. 2000-05-16 2022-01-08 Not clear
S Gasparini, D DiFrancesc. Action of serotonin on the hyperpolarization-activated cation current (Ih) in rat CA1 hippocampal neurons. The European journal of neuroscience vol 11 issue 9 1999 10510173 Our data indicate that 5-HT modulates Ih by shifting its activation curve to more positive voltages and by increasing its maximal conductance, and that this action is likely to contribute to the 5-HT modulation of excitability of CA1 cells. 1999-11-24 2022-01-08 Not clear
A Raurich, G Mengod, F Artigas, R Cort\\xc3\\xa9. Displacement of the binding of 5-HT(1A) receptor ligands to pre- and postsynaptic receptors by (-)pindolol. A comparative study in rodent, primate and human brain. Synapse (New York, N.Y.) vol 34 issue 1 1999 10459173 The affinity of (-)pindolol for presynaptic 5-HT(1A) receptors in the dorsal raphe nucleus was similar to that observed in postsynaptic locations, such as hippocampus (areas CA1, CA3 and dentate gyrus) or entorhinal cortex. 1999-10-20 2022-01-08 Not clear
Y Zheng, P F Smith, C L Darlingto. Noradrenaline and serotonin levels in the guinea pig hippocampus following unilateral vestibular deafferentation. Brain research vol 836 issue 1-2 1999 10415419 The aim of this study was to determine levels of noradrenaline (NA), serotonin (5-HT) and the 5-HT metabolite, 5-hydroxyindoleacetic acid (5-HIAA), in the CA1, CA2 and dentate gyrus (DG) regions of the ipsilateral and contralateral hippocampi, at 10 h following deafferentation of the peripheral vestibular nerve (UVD) in guinea pig, using high-performance liquid chromatography (HPLC) with electrochemical detection (ECD). 1999-10-15 2022-01-08 Not clear
Y Zheng, P F Smith, C L Darlingto. Noradrenaline and serotonin levels in the guinea pig hippocampus following unilateral vestibular deafferentation. Brain research vol 836 issue 1-2 1999 10415419 No significant changes in 5-HT or 5-HIAA levels were seen in the ipsilateral or contralateral CA1, CA2 or DG following UVD. 1999-10-15 2022-01-08 Not clear
V M Sandler, W N Ros. Serotonin modulates spike backpropagation and associated [Ca2+]i changes in the apical dendrites of hippocampal CA1 pyramidal neurons. Journal of neurophysiology vol 81 issue 1 1999 9914282 The effect of serotonin (5-HT) on somatic and dendritic properties was analyzed in pyramidal neurons from the CA1 region in slices from the rat hippocampus. 1999-03-22 2022-01-08 Not clear
H H Hansen, J D Mikkelse. Long-term effects on serotonin transporter mRNA expression of chronic neonatal exposure to a serotonin reuptake inhibitor. European journal of pharmacology vol 352 issue 2-3 1998 9716368 The expression of 5-HT transporter, 5-HT1A receptor, and 5-HT1B receptor mRNA was examined in the dorsal raphe nucleus and in the CA1 of the hippocampus by means of quantitative in situ hybridisation histochemistry. 1998-11-04 2022-01-08 rat
H H Hansen, J D Mikkelse. Long-term effects on serotonin transporter mRNA expression of chronic neonatal exposure to a serotonin reuptake inhibitor. European journal of pharmacology vol 352 issue 2-3 1998 9716368 A small but significant increase in 5-HT1B receptor mRNA expression in the CA1 was seen after clomipramine, but not after Lu 10-134-C, probably reflecting clomipramine's affinity for both the 5-HT and noradrenaline transporters as well as for a number of monoamine receptor sites. 1998-11-04 2022-01-08 rat
T M Cabrera-Vera, G Battagli. Prenatal exposure to fluoxetine (Prozac) produces site-specific and age-dependent alterations in brain serotonin transporters in rat progeny: evidence from autoradiographic studies. The Journal of pharmacology and experimental therapeutics vol 286 issue 3 1998 9732413 For example, in adult control offspring, densities of 5-HT transporters were significantly greater in the cingulate cortex (+33%), basolateral amygdala (+58%), and CA1 area of the hippocampus (+78%); but significantly lower in the temporal cortex (-65%) and median raphe (-25%). 1998-10-08 2022-01-08 rat
O Cases, C Lebrand, B Giros, T Vitalis, E De Maeyer, M G Caron, D J Price, P Gaspar, I Sei. Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 18 issue 17 1998 9712661 In the telencephalon, transient 5-HT immunolabeling is observed in neurons in the CA1 and CA3 fields of the hippocampus, the central amygdala, the indusium griseum, and the deep layers of the anterior cingulate and retrosplenial cortices. 1998-09-09 2022-01-08 mouse
P A Broderick, O Hope, P Jeanno. Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal. Progress in neuro-psychopharmacology & biological psychiatry vol 22 issue 2 1998 9608607 Real time, in vivo microvoltammetric studies were performed, using miniature carbon-based sensors, to concurrently detect norepinephrine (NE) release and serotonin (5-HT) release, in 2 separate electrochemical signals, within CA1 region of hippocampus in the freely moving and behaving, male, Sprague Dawley laboratory rat. 1998-08-11 2022-01-08 Not clear
P A Broderick, O Hope, P Jeanno. Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal. Progress in neuro-psychopharmacology & biological psychiatry vol 22 issue 2 1998 9608607 Time course studies showed that the mechanism of action of the triazolobenzodiazepine (TBZD), adinazolam, (Deracyn) is dramatically different from that of the classical benzodiazepine (BZD), diazepam (Valium, i.e., adinazolam increased, whereas diazepam decreased, 5-HT release within CA1 region of hippocampus in the freely moving and behaving rat. 1998-08-11 2022-01-08 Not clear
A M Pugliese, M B Passani, R Corradett. Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. British journal of pharmacology vol 124 issue 1 1998 9630348 Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. 1998-08-04 2022-01-08 Not clear
A M Pugliese, M B Passani, R Corradett. Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. British journal of pharmacology vol 124 issue 1 1998 9630348 Since WAY 100635 selectively antagonizes 5-HT1A receptor-mediated actions of 5-HT, our data also demonstrate that the inhibitory action of 5-HT on excitatory synaptic transmission in CA1 is mediated by 5-HT1A receptors. 1998-08-04 2022-01-08 Not clear
R Y Shen, R Andrad. 5-Hydroxytryptamine2 receptor facilitates GABAergic neurotransmission in rat hippocampus. The Journal of pharmacology and experimental therapeutics vol 285 issue 2 1998 9580630 5-Hydroxytryptamine (5-HT; serotonin) administration enhances GABAergic synaptic activity recorded in pyramidal neurons of the CA1 region of hippocampus. 1998-06-08 2022-01-08 Not clear
R Y Shen, R Andrad. 5-Hydroxytryptamine2 receptor facilitates GABAergic neurotransmission in rat hippocampus. The Journal of pharmacology and experimental therapeutics vol 285 issue 2 1998 9580630 Therefore, we reinvestigated the effects of 5-HT on GABAergic synaptic activity recorded in pyramidal cells of the CA1 region. 1998-06-08 2022-01-08 Not clear
W Hesen, Y J Karten, S V van de Witte, M Jo\\xc3\\xabl. Serotonin and carbachol induced suppression of synaptic excitability in rat CA1 hippocampal area: effects of corticosteroid receptor activation. Journal of neuroendocrinology vol 10 issue 1 1998 9510054 Serotonin (5HT) and the cholinergic analogue carbachol (CCh) act on neurons in the hippocampal CA1 area through pre- and post-synaptic receptors. 1998-04-30 2022-01-08 rat
W Hesen, Y J Karten, S V van de Witte, M Jo\\xc3\\xabl. Serotonin and carbachol induced suppression of synaptic excitability in rat CA1 hippocampal area: effects of corticosteroid receptor activation. Journal of neuroendocrinology vol 10 issue 1 1998 9510054 In the present study, we examined the consequences of steroid modulation of these post-synaptic membrane effects and/or possible pre-synaptic effects by 5HT and CCh for the excitability in the CA1 area, using extracellular field potential or intracellular recordings from individual pyramidal neurons. 1998-04-30 2022-01-08 rat
W Hesen, Y J Karten, S V van de Witte, M Jo\\xc3\\xabl. Serotonin and carbachol induced suppression of synaptic excitability in rat CA1 hippocampal area: effects of corticosteroid receptor activation. Journal of neuroendocrinology vol 10 issue 1 1998 9510054 In slices from adrenally intact rats, both 5HT (3-30 microM) and CCh (1-10 microM) induced a dose-dependent suppression of the synaptic field responses evoked in the CA1 area by stimulation of the Schaffer collaterals. 1998-04-30 2022-01-08 rat
W Hesen, Y J Karten, S V van de Witte, M Jo\\xc3\\xabl. Serotonin and carbachol induced suppression of synaptic excitability in rat CA1 hippocampal area: effects of corticosteroid receptor activation. Journal of neuroendocrinology vol 10 issue 1 1998 9510054 These data suggest that the steroids modulate post-synaptic but not pre-synaptic 5HT effects and that this modulation is reflected in the excitability of the CA1 region. 1998-04-30 2022-01-08 rat
P A Broderic. Alprazolam, diazepam, yohimbine, clonidine: in vivo CA1 hippocampal norepinephrine and serotonin release profiles under chloral hydrate anesthesia. Progress in neuro-psychopharmacology & biological psychiatry vol 21 issue 7 1998 9421826 In vivo microvoltammetric studies were performed using miniature carbon based sensors to detect NE release and concurrent 5-HT release, with 2 separate neural electrochemical signals, within CA1 region of hippocampus, in the chloral hydrate anesthetized rat. 1998-01-28 2022-01-08 Not clear
P A Broderic. Alprazolam, diazepam, yohimbine, clonidine: in vivo CA1 hippocampal norepinephrine and serotonin release profiles under chloral hydrate anesthesia. Progress in neuro-psychopharmacology & biological psychiatry vol 21 issue 7 1998 9421826 Time course studies showed that the alpha 2-adrenergic antagonist, yohimbine, an anxiogenic agent, increased both NE and 5-HT release in CA1 region of hippocampus; the alpha 2-adrenergic agonist, clonidine, decreased NE release and increased 5-HT release in the same region. 1998-01-28 2022-01-08 Not clear
K Tokarski, A Czyrak, M Ma\\xc4\\x87kowiak, K Wedzony, M Bija. Prolonged treatment with antidepressants increases the 5-HT1A-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding. Acta physiologica Hungarica vol 84 issue 3 1997 9219632 5-HT and 8-OH-DPAT decreased the amplitude of population spikes evoked in the CA1 cell layer by electrical stimulation of the stratum radiatum. 1997-09-05 2022-01-08 Not clear
J L Yau, J Noble, J R Seck. Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin. Neuroscience vol 78 issue 1 1997 9135093 5-Hydroxytryptamine1A receptor messenger RNA expression was decreased in CA1 in both groups of rats, but increased in the dentate gyrus only in corticosterone-fixed rats, suggesting 5-hydroxytryptamine differentially regulates expression of this gene within hippocampal subfields. 1997-08-01 2022-01-08 rat
J L Yau, J Noble, J R Seck. Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin. Neuroscience vol 78 issue 1 1997 9135093 5-hydroxytryptamine2C receptor messenger RNA was decreased in ventral CA1 only in adrenal-intact rats, suggesting a corticosterone effect, and decreased in the subiculum in both groups, indicating 5-hydroxytryptamine mediation. 1997-08-01 2022-01-08 rat
R K Dishman, K J Renner, S D Youngstedt, T G Reigle, B N Bunnell, K A Burke, H S Yoo, E H Mougey, J L Meyerhof. Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain research bulletin vol 42 issue 5 1997 9092882 Brain concentrations of norepinephrine (NE), dopamine (DA), dihydroxyphenylacetic acid (DOPAC), 5-hydroxytryptamine (5-HT), and 5-hydroxyindole acetic acid (5-HIAA) were assayed in the locus coeruleus (LC), dorsal raphe (DR), central amygdala (AC), hippocampus (CA1), arcuate nucleus, paraventricular nucleus (PVN), and midbrain central gray. 1997-07-01 2022-01-07 rat
R K Dishman, K J Renner, S D Youngstedt, T G Reigle, B N Bunnell, K A Burke, H S Yoo, E H Mougey, J L Meyerhof. Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain research bulletin vol 42 issue 5 1997 9092882 Sedentary controls, compared with wheel runners, had 31% higher 5-HIAA concentrations in CA1 and 30% higher 5-HIAA concentrations in AC after uncontrollable foot shock and had 28% higher 5-HT and 33% higher 5-HIAA concentrations in AC averaged across both foot shock conditions. 1997-07-01 2022-01-07 rat
K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology vol 48 issue 6 1997 9112695 Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. 1997-06-26 2022-01-08 rat
K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology vol 48 issue 6 1997 9112695 Effects of repeated treatment with antidepressant drugs on the reactivity of CA1 neurons to 5-hydroxytryptamine (5-HT), (+/-)-8-hydroxy-2-(dipropyl-amino)-tetralin (8-OH-DPAT)--the 5-HT1A receptor agonist, and the zacopride-5-HT4 receptor agonist were examined in the rat hippocampus ex vivo. 1997-06-26 2022-01-08 rat
K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology vol 48 issue 6 1997 9112695 It has been concluded that adaptive changes in the responsiveness of CA1 cells to 5-HT, 8-OH-DPAT and zacopride, induced by repeated administration of antidepressant drugs do not involve presynaptic effects on excitatory synaptic transmission. 1997-06-26 2022-01-08 rat
S G Beck, S Birnstiel, K C Choi, W A Poulio. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 281 issue 1 1997 9103487 Fluoxetine treatment increased the potency of 5-HT for the 5-HT1A receptor-mediated hyperpolarization in area CA1, but not area CA3, and decreased the potency of baclofen for the GABA(B) receptor-mediated hyperpolarization in area CA1, but not area CA3. 1997-05-02 2022-01-07 rat
A Fletcher, E A Forster, D J Bill, G Brown, I A Cliffe, J E Hartley, D E Jones, A McLenachan, K J Stanhope, D J Critchley, K J Childs, V C Middlefell, L Lanfumey, R Corradetti, A M Laporte, H Gozlan, M Hamon, C T Douris. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist. Behavioural brain research vol 73 issue 1-2 1996 8788530 In vitro electrophysiological studies demonstrated that WAY-100635 had no 5-HT1A receptor agonist actions, but dose-dependently blocked the effects of agonists at both the postsynaptic 5-HT1A receptor in the CA1 region of the hippocampus, and the somatodendritic 5-HT1A receptor located on dorsal raphe 5-HT neurones. 1996-12-04 2022-01-07 mouse
W Hesen, M Jo\\xc3\\xabl. Modulation of 5HT1A responsiveness in CA1 pyramidal neurons by in vivo activation of corticosteroid receptors. Journal of neuroendocrinology vol 8 issue 6 1996 8809673 Altogether, this study presents further evidence that 5HT transmission in hippocampal CA1 area is modulated by differential steroid receptor activation as may occur under physiological circumstances due to different plasma concentrations of corticosterone. 1996-11-21 2022-01-07 rat
D Schmitz, R M Empson, U Heineman. Serotonin and 8-OH-DPAT reduce excitatory transmission in rat hippocampal area CA1 via reduction in presumed presynaptic Ca2+ entry. Brain research vol 701 issue 1-2 1996 8925288 Using concentrations of 5-HT within a range of 10-50 microM we observed no change in excitatory postsynaptic potentials (EPSPs) in CA1 cells evoked by Schaffer collateral stimulation. 1996-10-25 2022-01-07 Not clear
D Umbriaco, S Garcia, C Beaulieu, L Descarrie. Relational features of acetylcholine, noradrenaline, serotonin and GABA axon terminals in the stratum radiatum of adult rat hippocampus (CA1). Hippocampus vol 5 issue 6 1996 8646286 In a well-defined sector of adult rat hippocampus (CA1, stratum radiatum), the ultrastructural features of acetylcholine (ACh), noradrenaline (NA), serotonin (5-HT) and GABA axon terminals (varicosities) were compared by electron microscopy after immunostaining with antibodies against choline acetyltransferase, NA, 5-HT and glutamic acid decarboxylase. 1996-07-23 2022-01-07 Not clear
D Schmitz, R M Empson, U Heineman. Serotonin reduces inhibition via 5-HT1A receptors in area CA1 of rat hippocampal slices in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 15 issue 11 1995 7472476 We studied the effects of serotonin (5-HT) on intrinsic and synaptic responses of hippocampal CA1 cells. 1995-12-26 2022-01-07 Not clear
N Haddjeri, P Blie. Pre- and post-synaptic effects of the 5-HT3 agonist 2-methyl-5-HT on the 5-HT system in the rat brain. Synapse (New York, N.Y.) vol 20 issue 1 1995 7624830 Microiontophoretic applications of 5-HT and of the 5-HT3 agonist 2-methyl-5-HT produced a current-dependent suppression of firing activity of both hippocampal (CA1 and CA3) and cortical neurons in anesthetized rats. 1995-08-31 2022-01-07 rat
M Bijak, M Pap. The effect of chronic treatment with imipramine on the responsiveness of hippocampal CA1 neurons to phenylephrine and serotonin in a chronic mild stress model of depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology vol 5 issue 1 1995 7613100 The effect of chronic mild stress (CMS) and chronic treatment with the tricyclic antidepressant drug imipramine (10 mg/kg/day for 5 weeks) on neuronal responsiveness to the alpha 1-noradrenergic agonist phenylephrine and serotonin (5-HT) was examined ex vivo, in the CA1 cell layer of the rat hippocampal slice preparation. 1995-08-24 2022-01-07 Not clear
S Birnstiel, S G Bec. Modulation of the 5-hydroxytryptamine4 receptor-mediated response by short-term and long-term administration of corticosterone in rat CA1 hippocampal pyramidal neurons. The Journal of pharmacology and experimental therapeutics vol 273 issue 3 1995 7791083 Corticosterone (CT) treatment decreases the magnitude of the 5-hydroxytryptamine (5-HT)1A receptor-mediated hyperpolarization in rat CA1 hippocampal pyramidal neurons. 1995-07-21 2022-01-07 rat
J L Yau, P A Kelly, J R Seck. Increased glucocorticoid receptor gene expression in the rat hippocampus following combined serotonergic and medial septal cholinergic lesions. Brain research. Molecular brain research vol 27 issue 1 1995 7877448 In the present study we found that combined medial septal cholinergic and central 5-HT lesions increase hippocampal GR mRNA expression, specifically in CA1 and CA2 subfields, whereas MR mRNA expression was similar to controls. 1995-04-06 2022-01-07 rat
G E Torres, Y Chaput, R Andrad. Cyclic AMP and protein kinase A mediate 5-hydroxytryptamine type 4 receptor regulation of calcium-activated potassium current in adult hippocampal neurons. Molecular pharmacology vol 47 issue 1 1995 7838128 In the CA1 region of the hippocampus, activation of serotonin receptors of the 5-hydroxytryptamine (5-HT)4 subtype increases membrane excitability by reducing the calcium-activated potassium current responsible for the slow afterhyperpolarization observed in these cells. 1995-02-28 2022-01-07 Not clear
M Bijak, K Tokarsk. Prolonged administration of imipramine and (+)-oxaprotiline, but not citalopram, results in sensitization of the rat hippocampal CA1 neurons to serotonin ex vivo. Polish journal of pharmacology vol 46 issue 3 1995 8000448 Prolonged (14 days, twice daily), but not acute, application of imipramine and (+)-oxaprotiline (10 mg/kg) induced sensitization of hippocampal CA1 neurons to the inhibitory effect of 5-hydroxytryptamine (5-HT), as studied ex vivo in the rat hippocampal slice preparation. 1995-01-25 2022-01-07 Not clear
M Frankfurt, C R McKittrick, V N Luin. Short-term fluoxetine treatment alters monoamine levels and turnover in discrete brain nuclei. Brain research vol 650 issue 1 1994 7525014 The major metabolite of 5-HT, 5-hydroxyindoleacetic acid (5-HIAA), was decreased by fluoxetine treatment in the ventromedial hypothalamic nucleus (VMN), the lateral hypothalamic area and the CA1 region of the hippocampus. 1994-12-07 2022-01-07 rat
L Ballerini, R Corradetti, A Nistri, A M Pugliese, G Stocc. Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin releasing hormone on rat hippocampal CA1 neurons. The European journal of neuroscience vol 6 issue 6 1994 7952282 Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin releasing hormone on rat hippocampal CA1 neurons. 1994-12-07 2022-01-07 Not clear
L Ballerini, R Corradetti, A Nistri, A M Pugliese, G Stocc. Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin releasing hormone on rat hippocampal CA1 neurons. The European journal of neuroscience vol 6 issue 6 1994 7952282 Intracellular recording from CA1 neurons of the rat hippocampal slice preparation was used to examine the possibility of functional interactions between 5-hydroxytryptamine (5-HT) and thyrotropin releasing hormone (TRH), which act as cotransmitters in other areas of the central nervous system. 1994-12-07 2022-01-07 Not clear
G J Blatt, J C Chen, D L Rosene, L Volicer, J R Galle. Prenatal protein malnutrition effects on the serotonergic system in the hippocampal formation: an immunocytochemical, ligand binding, and neurochemical study. Brain research bulletin vol 34 issue 5 1994 8082044 In the present investigation, compared to well-nourished controls, 220 day malnourished rats exhibited a decrease in the 5-HT fiber density in the dentate gyrus (DG) and CA3 subfield and, a 15-25% decrease 5-HT uptake sites assayed with [3H]-citalopram in CA3 and CA1. 1994-10-13 2022-01-07 rat
P D Hrdina, T B V. Chronic fluoxetine treatment upregulates 5-HT uptake sites and 5-HT2 receptors in rat brain: an autoradiographic study. Synapse (New York, N.Y.) vol 14 issue 4 1994 8248854 Chronic administration of fluoxetine produced significant increases in the density of 5-HT uptake sites in layers of frontoparietal cortex (by 32-43%), of striate cortex (by 55%), in CA1 field of hippocampus (by 111%) and in superior colliculus (by 20%). 1994-01-03 2022-01-07 Not clear
H Uneyama, M Munakata, N Akaik. 5-HT response of rat hippocampal pyramidal cell bodies. Neuroreport vol 3 issue 7 1992 1421122 Serotonin (5-HT) responses of pyramidal neurones freshly dissociated from rat ventral hippocampal CA1 region were investigated by using nystatin-perforated whole-cell recording. 1992-12-14 2022-01-07 Not clear
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 263 issue 1 1992 1403796 5-hydroxytryptamine (5-HT) hyperpolarizes hippocampal pyramidal cells in both areas CA1 and CA3 through an increase in potassium conductance. 1992-11-20 2022-01-07 Not clear
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 263 issue 1 1992 1403796 The 5-HT1 agonist 5-carboxyamidotryptamine and 5-HT were full agonists and the 5-HT1A-selective ligand 8-hydroxydipropyl-aminotetralin hydrobromide was a partial agonist in both CA3 and CA1. 1992-11-20 2022-01-07 Not clear
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 263 issue 1 1992 1403796 The agonists were a half-log unit less potent and the maximum response elicited by 5-carboxyamidotryptamine and 5-HT was greater in area CA3 than in area CA1. 1992-11-20 2022-01-07 Not clear
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 263 issue 1 1992 1403796 Based on these results, we conclude that the hyperpolarization elicited by 5-HT in areas CA1 and CA3 is mediated by the 5-HT1A receptor. 1992-11-20 2022-01-07 Not clear
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.) vol 10 issue 4 1992 1585262 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. 1992-06-18 2022-01-07 Not clear
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.) vol 10 issue 4 1992 1585262 In the presence of spiperone to block the 5-HT1A-mediated inhibition of pyramidal cell activity, 5-hydroxytryptamine (serotonin, 5-HT) produces a rapid transient increase in amplitude of the extracellularly recorded population spike from area CA1 of the hippocampus. 1992-06-18 2022-01-07 Not clear
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.) vol 10 issue 4 1992 1585262 Intracellular recording techniques in area CA1 of rat hippocampal slices were used to identify the ionic mechanism and to characterize the 5-HT receptor mediating this excitatory response to 5-HT. 1992-06-18 2022-01-07 Not clear
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.) vol 10 issue 4 1992 1585262 We conclude that 5-HT produces a fast excitatory response by increasing subthreshold conductance in CA1 hippocampal pyramidal cells. 1992-06-18 2022-01-07 Not clear
R Corradetti, L Ballerini, A M Pugliese, G Pepe. Serotonin blocks the long-term potentiation induced by primed burst stimulation in the CA1 region of rat hippocampal slices. Neuroscience vol 46 issue 3 1992 1545909 The effect of 5-hydroxytryptamine on the induction of long-term potentiation by a train of high frequency pulses (100 Hz; 1 s) or by a stimulation consisting of one burst of five pulses at 100 Hz delivered 170 ms after a single pulse (primed burst) was investigated in the CA1 region of the rat hippocampal slice in vitro with extracellular recordings. 1992-04-13 2022-01-09 Not clear
F A Dijcks, G S Ruigt, J S de Graa. Antidepressants affect amine modulation of neurotransmission in the rat hippocampal slice--I. Delayed effects. Neuropharmacology vol 30 issue 11 1992 1663591 The effects of long-term treatment with the antidepressant drugs, desipramine (DMI) and mianserin (MIA) on neurotransmission in the hippocampal slice were studied by examining the actions of serotonin (5-HT), isoprenaline and (+/-)-baclofen on the population spike in the pyramidal cell layer, recorded in area CA1. 1992-03-05 2022-01-07 Not clear
F A Dijcks, G S Ruigt, J S de Graa. Antidepressants affects amine modulation of neurotransmission in the rat hippocampal slice--II. Acute effects. Neuropharmacology vol 30 issue 11 1992 1663592 The effects of this treatment with single doses of DMI and MIA on neurotransmission in the hippocampal slice, were studied by examining the actions of serotonin (5-HT), isoprenaline and (+/-)-baclofen on the population spike of the pyramidal cell layer, recorded in area CA1. 1992-03-05 2022-01-07 Not clear
J M Klancnik, A Obenaus, A G Phillips, K G Baimbridg. The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat. Neuropharmacology vol 30 issue 11 1992 1837848 The effects of serotonin (5-HT), the 5-HT1A receptor subtype agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and the 5-HT2 receptor subtype agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on electrophysiological responses in the dentate gyrus and area CA1 were examined in the in vitro hippocampal slice preparation. 1992-03-05 2022-01-07 Not clear
J M Klancnik, A Obenaus, A G Phillips, K G Baimbridg. The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat. Neuropharmacology vol 30 issue 11 1992 1837848 The effects of 8-OH-DPAT in both regions were attenuated significantly by the serotonergic antagonist methysergide, as were the effects of 5-HT on the population spike in the CA1. 1992-03-05 2022-01-07 Not clear
P A Broderick, M F Pierce. 5-HT1A agonists uncouple noradrenergic somatodendritic impulse flow and terminal release. Brain research bulletin vol 27 issue 5 1992 1684526 In CA1 region of hippocampus, both buspirone and ipsapirone significantly depressed NE release with potencies greater than those required for the significant depression of 5-HT release. 1992-02-06 2022-01-07 Not clear
P Van den Hooff, M Galva. Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice. European journal of pharmacology vol 196 issue 3 1991 1893914 The actions of 5-hydroxytryptamine (5-HT) and the 5-HT1A receptor ligand MDL 73005EF on neuronal activity in the CA1 region of rat hippocampal slices in vitro were recorded using intra- and extracellular recording techniques. 1991-10-24 2022-01-07 Not clear
R Andrade, Y Chapu. 5-Hydroxytryptamine4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus. The Journal of pharmacology and experimental therapeutics vol 257 issue 3 1991 2046027 Hippocampal pyramidal neurons of the CA1 region express 5-hydroxytryptamine (serotonin, 5-HT) receptors which, upon activation, elicit a slow membrane depolarization and a decrease in the calcium-activated afterhyperpolarization present in these cells. 1991-07-12 2022-01-07 Not clear
Y Chaput, R C Araneda, R Andrad. Pharmacological and functional analysis of a novel serotonin receptor in the rat hippocampus. European journal of pharmacology vol 182 issue 3 1990 2226619 The present results thus suggest the presence in the CA1 region of the hippocampus of a novel 5-HT receptor at which BRL 24924 functions as a selective antagonist and which is capable of mediating slow excitatory responses in central neurons. 1990-12-12 2022-01-07 Not clear
Y Chaput, R C Araneda, R Andrad. Pharmacological and functional analysis of a novel serotonin receptor in the rat hippocampus. European journal of pharmacology vol 182 issue 3 1990 2226619 Administration of serotonin (5-hydroxytryptamine, 5-HT) to pyramidal cells of the CA1 region of the hippocampus results in a hyperpolarizing response which is followed by a rebound depolarization and a decrease in the calcium-activated afterhyperpolarization (AHP). 1990-12-12 2022-01-07 Not clear
N Gurevich, P H Wu, P L Carle. Serotonin agonist and antagonist actions in hippocampal CA1 neurons. Canadian journal of physiology and pharmacology vol 68 issue 5 1990 2340447 Spiperone, a nonspecific 5-HT antagonist, and ritanserin, a putative specific 5-HT2 receptor antagonist, depolarized CA1 neurons with little or no change in input resistance. 1990-06-28 2022-01-07 Not clear
N Gurevich, P H Wu, P L Carle. Serotonin agonist and antagonist actions in hippocampal CA1 neurons. Canadian journal of physiology and pharmacology vol 68 issue 5 1990 2340447 The actions of serotonin (5-HT) and its putative agonists and antagonists were examined in vitro on hippocampal CA1 neurons using intracellular recordings, demonstrating that the cellular pharmacological effects can not necessarily be predicted from binding characteristics alone. 1990-06-28 2022-01-07 Not clear
A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology vol 29 issue 2 1990 1970426 Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. 1990-05-30 2022-01-07 rat
S G Beck, P M Hallora. Imipramine alters beta-adrenergic, but not serotonergic, mediated responses in rat hippocampal pyramidal cells. Brain research vol 504 issue 1 1990 2557127 This study investigated acute and chronic effects of imipramine on intracellularly-recorded responses mediated by 5-HT and beta-adrenergic receptors on pyramidal cells from area CA1 of rat hippocampal slices maintained in vitro. 1990-02-06 2022-01-07 Not clear
F Radja, G Daval, M B Emerit, M C Gallissot, M Hamon, D Verg\\xc3\\xa. Selective irreversible blockade of 5-hydroxytryptamine1A and 5-hydroxytryptamine1C receptor binding sites in the rat brain by 8-MeO-2'-chloro-PAT: a quantitative autoradiographic study. Neuroscience vol 31 issue 3 1990 2531850 A marked reduction (-50% to -75%) of [3H]8-OH-DPAT and [125I]BH-8-MeO-N-PAT specific binding to 5-hydroxytryptamine1A sites in the hippocampus (CA1 area) and the dorsal raphe nucleus, and of [3H]5-hydroxytryptamine specific binding to 5-hydroxytryptamine1C sites in the choroid plexus was found in sections exposed to 1 microM 8-MeO-2'-chloro-PAT and then washed extensively. 1990-01-25 2022-01-07 Not clear
M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research vol 502 issue 1 1990 2531014 The responses of CA1 neurons to topical application of serotonin (5-HT) and selective 5-HT1a and 5-HT1b agonists were examined with intracellular recording in the hippocampal slice. 1990-01-04 2022-01-07 Not clear
S G Bec. 5-Carboxyamidotryptamine mimics only the 5-HT elicited hyperpolarization of hippocampal pyramidal cells via 5-HT1A receptor. Neuroscience letters vol 99 issue 1-2 1989 2748003 Perfusion of the rat hippocampal slice in vitro by 5-hydroxytryptamine (5-HT) elicits 3 distinct actions recorded intracellularly from pyramidal cells in area CA1: a hyperpolarization, reduction in spike train elicited afterhyperpolarization (AHP) and depolarization. 1989-08-18 2022-01-07 Not clear
J V Halliwell, E A Grov. 9-Amino-1,2,3,4-tetrahydroacridine (THA) blocks agonist-induced potassium conductance in rat hippocampal neurones. European journal of pharmacology vol 163 issue 2-3 1989 2721578 More sensitive to the action of THA was the outward K+ current activated in CA1 neurones by 5-HT, adenosine and baclofen. 1989-07-12 2022-01-07 Not clear
A Dresse, J Scuv\\xc3\\xa9e-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology vol 11 Suppl 2 issue 1988 3180117 The interaction of tianeptine and clomipramine with the response of CA1 cells to iontophoretically applied 5-HT or GABA was also investigated. 1988-12-20 2022-01-07 Not clear
A Dresse, J Scuv\\xc3\\xa9e-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology vol 11 Suppl 2 issue 1988 3180117 The iontophoretic application of tianeptine did not modify the response of CA1 cells to 5-HT or GABA but decreased the recovery time after 5-HT and GABA. 1988-12-20 2022-01-07 Not clear
A Dresse, J Scuv\\xc3\\xa9e-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology vol 11 Suppl 2 issue 1988 3180117 The iontophoretic application of clomipramine potentiated the response of CA1 cells to 5-HT but not to GABA and increased the recovery time after 5-HT and GABA. 1988-12-20 2022-01-07 Not clear
G A Foster, M Schultzberg, F H Gage, A Bj\\xc3\\xb6rklund, T H\\xc3\\xb6kfelt, A C Cuello, A A Verhofstad, T J Visser, P C Emso. Transmitter expression and morphological development of embryonic medullary and mesencephalic raph\\xc3\\xa9 neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Experimental brain research vol 70 issue 2 1988 2454837 Outgrowth of 5HT-immunoreactive fibres was extensive, and displayed the typical pattern of 5HT innervation in the normal hippocampus-the densest plexuses were found in the dentate gyrus, with sparser networks in the CA1 and CA2 regions. 1988-07-29 2022-01-07 rat
P H Wu, N Gurevich, P L Carle. Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. Neuroscience letters vol 86 issue 1 1988 2966313 Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. 1988-06-02 2022-01-07 Not clear
P H Wu, N Gurevich, P L Carle. Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. Neuroscience letters vol 86 issue 1 1988 2966313 Serotonin (5-HT) usually induced a slow hyperpolarization lasting several minutes on first drop-application onto CA1 neurons. 1988-06-02 2022-01-07 Not clear
R Andrade, R A Nicol. Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. The Journal of physiology vol 394 issue 1988 3443977 The actions of serotonin (5-HT) on pyramidal cells of the CA1 region of the rat hippocampus were characterized using intracellular recording in in vitro brain slices. 1988-05-12 2022-01-07 Not clear
R Andrade, R A Nicol. Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology vol 336 issue 1 1987 2888027 Since the buspirone induced hyperpolarization was also accompanied by a surmountable antagonism of 5-HT responses, these results indicate that buspirone behaves as a partial agonist at a subpopulation of 5-HT receptors in the CA1 region of the hippocampus. 1987-10-22 2022-01-07 Not clear
M J Rowan, R Anwy. Neurophysiological effects of buspirone and isapirone in the hippocampus: comparison with 5-hydroxytryptamine. European journal of pharmacology vol 132 issue 1 1987 2880731 The neurophysiological effects of two novel anxiolytic compounds, buspirone and isapirone (TVX Q 7821), were compared with those of 5-hydroxytryptamine (5-HT) on the population spike in the CA1 region of the rat hippocampal slice. 1987-04-01 2022-01-07 Not clear
N J Penington, R J Reiffenstei. Lack of effect of antagonists on serotonin-induced inhibition in rat hippocampus. Canadian journal of physiology and pharmacology vol 64 issue 11 1987 3791042 Four putative central nervous system 5-hydroxytryptamine antagonists, methysergide, cyproheptadine, metergoline, and ketanserin and also lysergic acid diethylamide were applied by iontophoresis to firing CA1 hippocampal pyramidal cells to test their action on the inhibition produced by 5-hydroxytryptamine. 1987-02-18 2022-01-07 Not clear
N J Penington, R J Reiffenstei. Lack of effect of antagonists on serotonin-induced inhibition in rat hippocampus. Canadian journal of physiology and pharmacology vol 64 issue 11 1987 3791042 The results of this study suggest that CA1 hippocampus is another structure, innervated by serotonergic neurones, where all (peripherally active) serotonin antagonists tested to date are ineffective against 5-hydroxytryptamine induced inhibition. 1987-02-18 2022-01-07 Not clear
M Dowdall, C De Montign. Effect of atmospheric ions on hippocampal pyramidal neuron responsiveness to serotonin. Brain research vol 342 issue 1 1985 2412639 Unitary extracellular recordings from pyramidal neurons of the CA1 and CA3 regions of the dorsal hippocampus were obtained under urethane anesthesia, and their responsiveness to microiontophoretically applied acetylcholine (ACh), norepinephrine (NE) and 5-HT was assessed. 1985-11-12 2022-01-07 rat
P K Stanton, J M Sarve. Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 5 issue 8 1985 4040556 Therefore, we have examined the effects of depletion of NE or 5-HT on LTP in the dentate and field CA1 of the isolated in vitro hippocampal slice preparation. 1985-09-19 2022-01-07 Not clear
A Biegon, T C Rainbow, B S McEwe. Corticosterone modulation of neurotransmitter receptors in rat hippocampus: a quantitative autoradiographic study. Brain research vol 332 issue 2 1985 2986762 ADX for one week causes an increase in [3H]5-HT binding to 5-HT1 receptors which is significant in the CA1 cell field. 1985-06-25 2022-01-07 rat
A Biegon, T C Rainbow, B S McEwe. Corticosterone modulation of neurotransmitter receptors in rat hippocampus: a quantitative autoradiographic study. Brain research vol 332 issue 2 1985 2986762 CORT treatment of ADX rats for 3-5 days results in localized reductions of [3H]5-HT binding including a partial reversal of the increase observed after ADX in CA1. 1985-06-25 2022-01-07 rat
S G Beck, J Goldfar. Serotonin produces a reversible concentration dependent decrease of population spikes in rat hippocampal slices. Life sciences vol 36 issue 6 1985 3968977 Superfusion of slices of rat dorsal hippocampus in vitro with serotonin (5-HT) reversibly decreases the amplitude of the CA1 population spike evoked by stimulation of stratum radiatum. 1985-03-15 2022-01-07 Not clear
R C Meibach, S G Beck, S Maayani, J P Gree. Regional differences in binding of [3H]LSD and [3H]5-HT in calf hippocampal slices revealed by radioautography and rapid filtration studies. Brain research vol 307 issue 1-2 1984 6467009 Previous radioautographic experiments demonstrated that binding sites labeled by [3H]5-HT and [3H]LSD in rat brain were seen in all layers of CA1, CA4 and the dentate gyrus but not in fields CA2 and CA3 of the hippocampus. 1984-10-19 2022-01-07 Not clear
R C Meibach, S G Beck, S Maayani, J P Gree. Regional differences in binding of [3H]LSD and [3H]5-HT in calf hippocampal slices revealed by radioautography and rapid filtration studies. Brain research vol 307 issue 1-2 1984 6467009 Binding of both [3H]5-HT and [3H]LSD by homogenates of CA1 and dentate gyrus, but not of CA3, was saturable. 1984-10-19 2022-01-07 Not clear
M Sega. Regional differences in neuronal responses to 5-HT: intracellular studies in hippocampal slices. Journal de physiologie vol 77 issue 2-3 1981 7288653 It is suggested that 5-HT causes an increase in K+ conductance in regions CA1 and DG and that this results in hyperpolarization. 1981-12-22 2022-01-07 Not clear
H Jahnse. The action of 5-hydroxytryptamine on neuronal membranes and synaptic transmission in area CA1 of the hippocampus in vitro. Brain research vol 197 issue 1 1980 6249462 The action of 5-hydroxytryptamine on neuronal membranes and synaptic transmission in area CA1 of the hippocampus in vitro. 1980-10-24 2022-01-07 Not clear
H Jahnse. The action of 5-hydroxytryptamine on neuronal membranes and synaptic transmission in area CA1 of the hippocampus in vitro. Brain research vol 197 issue 1 1980 6249462 Cell membrane properties and synaptic transmission were examined by intracellular recording from the CA1 region of hippocampal slices during application of 5-hydroxytryptamine (5-HT). 1980-10-24 2022-01-07 Not clear
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