| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melike Doğan Ünlü, Sanem Aşçı, Orhan İmeci, Adem Milletsever, Özlem Özmen, Serdar Sezer, Serpil Demirc. A novel insight into the neuroprotective effects of cannabidiol: maintained apelin/dopamine synthesis, NRF2 signaling, and AKT/CREB/BDNF gene expressions. Acta neurobiologiae experimentalis. vol 84. issue 1. 2024-04-08. PMID:38587319. |
additionally, purkinje cell loss in the cerebellum, as well as neuronal loss in the cerebral cortex and hippocampus, were found throughout the lps group. |
2024-04-08 |
2024-04-10 |
rat |
| Aïda Padilla-Ferrer, Alex Carrete, Anne Simon, Delphine Meffre, Mehrnaz Jafarian-Tehran. A disintegrin and Metalloprotease 10 expression within the murine central nervous system. Brain research. 2024-03-28. PMID:38548249. |
we observed adam10 expression through the whole cns, with a strong expression in the hippocampus, in the hypothalamus and in the cerebral and piriform cortex in the brain, in the purkinje and in granular cell layers in the cerebellum and in the spinal cord to a lower extent. |
2024-03-28 |
2024-03-31 |
mouse |
| Paola Rodríguez-Quintero, Moisés Rubio-Osornio, Eric Uribe, Wilhelm Moreno, Luis A Marín-Castañeda, Zayra Morales, Alonso Portila, David Vázquez, Carmen Rubi. Exposure to Ozone Downregulates Bcl-2 and Increases Executing Caspases-3 and -8 in the Hippocampus, Frontal Cortex, and Cerebellum of Rats. Cureus. vol 16. issue 2. 2024-03-22. PMID:38516464. |
conclusions this study demonstrates that acute exposure to 1 ppm of ozone can trigger neuronal apoptosis in the frontal cortex, hippocampus, and cerebellum of rats, primarily through the activation of the extrinsic apoptosis pathway via caspase-8 and caspase-3. |
2024-03-22 |
2024-03-24 |
rat |
| Houéfa Armelle Lokossou, Giovanni Rabuffo, Monique Bernard, Christophe Bernard, Angèle Viola, Teodora-Adriana Perles-Barbacar. Impact of the day/night cycle on functional connectome in ageing male and female mice. NeuroImage. 2024-03-15. PMID:38490583. |
in males, brain activity was significantly higher in the left hippocampus, the retrosplenial cortex, the superior colliculus, and the cerebellum regardless of lighting condition; consistent with the role of these structures in memory formation and integration, sleep, and sex-differences in memory processing. |
2024-03-15 |
2024-03-18 |
mouse |
| Xihan Guo, Jianfei Li, Yanmei Qi, Juanlin Chen, Minyan Jiang, Lina Zhu, Zetong Liu, Han Wang, Gongwu Wang, Xu Wan. Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic manner. Aging cell. 2024-03-07. PMID:38450924. |
tl was measured in brain (prefrontal cortex, cerebellum, pituitary gland, and hippocampus), colon and skin, and mn was measured in bone marrow in 6- to 14-month-old mice. |
2024-03-07 |
2024-03-09 |
mouse |
| Jessica A Bernar. Cerebello-Hippocampal Interactions in the Human Brain: A New Pathway for Insights Into Aging. Cerebellum (London, England). 2024-03-04. PMID:38438826. |
work in the human brain has provided evidence for interactions between the cerebellum and hippocampus, though primarily this has been in the context of spatial navigation. |
2024-03-04 |
2024-03-07 |
human |
| Álvaro González-Domínguez, Ana Sayago, Ángeles Fernández-Recamales, Raúl González-Domíngue. Mass Spectrometry-Based Metabolomics Multi-platform for Alzheimer's Disease Research. Methods in molecular biology (Clifton, N.J.). vol 2785. 2024-03-01. PMID:38427189. |
these procedures have been optimized for the analysis of multiple biological samples from human patients and transgenic animal models, including blood serum, various brain regions (e.g., hippocampus, cortex, cerebellum, striatum, olfactory bulbs), and other peripheral organs (e.g., liver, kidney, spleen, thymus). |
2024-03-01 |
2024-03-03 |
human |
| Yao Wu, Josepheen De Asis-Cruz, Catherine Limperopoulo. Brain structural and functional outcomes in the offspring of women experiencing psychological distress during pregnancy. Molecular psychiatry. 2024-02-28. PMID:38418579. |
elevated maternal psychological distress is associated with changes in fetal brain structure and function, including reduced hippocampal and cerebellar volumes, increased cerebral cortical gyrification and sulcal depth, decreased brain metabolites (e.g., choline and creatine levels), and disrupted functional connectivity. |
2024-02-28 |
2024-03-02 |
Not clear |
| Dominic Osei, Eveline Baumgart-Vogt, Barbara Ahlemeyer, Christiane Herde. Tumor Necrosis Factor-α Receptor 1 Mediates Borna Disease Virus 1-Induced Changes in Peroxisomal and Mitochondrial Dynamics in Neurons. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339126. |
using different mouse lines-i.e., tumor necrosis factor-α transgenic (tnftg; to pro-inflammatory status), tnf receptor-1 knockout (tnfr1ko), and tnfr2ko mice in comparison to wild-type (wt) mice-we analyzed the abundances of both organelles and their main antioxidant enzymes, catalase and superoxide dismutase 2 (sod2), in neurons of the hippocampal, cerebral, and cerebellar cortices. |
2024-02-10 |
2024-02-12 |
mouse |
| Yijie Huang, Chong Shen, Wei Zhao, Youlan Shang, Yisong Wang, Hui-Ting Zhang, Ruoyun Ouyang, Jun Li. Genes Associated with Altered Brain Structure and Function in Obstructive Sleep Apnea. Biomedicines. vol 12. issue 1. 2024-01-26. PMID:38275376. |
compared to the hcs, the osa group exhibited increased alff values in the left hippocampus (t = 5.294), amygdala (t = 4.176), caudate (t = 4.659), cerebellum (t = 5.896), and decreased alff values in the left precuneus (t = -4.776). |
2024-01-26 |
2024-01-28 |
human |
| Natalie A Tan, Angelica M Alvarado Carpio, H Craig Heller, Elsa C Pittara. Behavioral and Neuronal Characterizations, across Ages, of the TgSwDI Mouse Model of Alzheimer's Disease. Genes. vol 15. issue 1. 2024-01-23. PMID:38254938. |
thus, we use behavioral tests (t-maze, novel object recognition (nor), novel object location (nol)) to study long-term and working memory, and immunostaining to study β-amyloid plaque deposits, as well as brain size, in hippocampal, cerebellum, and cortical slices in tgswdi and wild-type (wt) mice at 3, 5, 8, and 12 months old. |
2024-01-23 |
2024-01-25 |
mouse |
| Patrycja Kupnicka, Joanna Listos, Maciej Tarnowski, Agnieszka Kolasa, Patrycja Kapczuk, Anna Surówka, Jakub Kwiatkowski, Kamil Janawa, Dariusz Chlubek, Irena Baranowska-Bosiack. The Effect of Prenatal and Neonatal Fluoride Exposure to Morphine-Induced Neuroinflammation. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255899. |
we provide evidence that both morphine administration and fluoride exposure have an impact on the inflammatory response by altering the expression of cox-1, cox-2, ionized calcium-binding adapter molecule (iba1), and glial fibrillary acidic protein (gfap) in brain structures involved in dependence development, such as the prefrontal cortex, striatum, hippocampus, and cerebellum. |
2024-01-23 |
2024-01-25 |
rat |
| Amanda C Wylie, Sarah J Short, Rebecca C Fry, W Roger Mills-Koonce, Cathi Proppe. Maternal prenatal lead levels and neonatal brain volumes: Testing moderations by maternal depressive symptoms and family income. Neurotoxicology and teratology. 2024-01-20. PMID:38244816. |
leveraging a sample of 101 mother-infant dyads followed beginning in mid-pregnancy, we examined the main effects of prenatal urinary lead levels on neonatal lateralized brain volumes (left and right hippocampus, amygdala, cerebellum, frontal lobes) and total gray matter. |
2024-01-20 |
2024-01-23 |
Not clear |
| Yanan Deng, Liping Ma, Ziwei Du, Huixin Ma, Yuxi Xia, Liran Ping, Zhaoxing Chen, Yinghua Zhan. The Notch1/Hes1 pathway regulates Neuregulin 1/ErbB4 and participates in microglial activation in rats with VPA-induced autism. Progress in neuro-psychopharmacology & biological psychiatry. 2024-01-19. PMID:38242426. |
our results suggest that the levels of notch1, hes1, nrg1, and phosphorylated erbb4 in the cerebellum (cb), hippocampus (hc), and prefrontal cortex (pfc) were increased in rats with valproic acid (vpa)-induced autism compared to those in the con group. |
2024-01-19 |
2024-01-22 |
rat |
| Kara Snyder, C Edward Dixon, Jeremy Henchir, Kiersten Gorse, Vincent A Vagni, Keri Janesko-Feldman, Patrick M Kochanek, Travis C Jackso. Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice. Experimental neurology. 2024-01-13. PMID:38218585. |
gene knockout of rna binding motif 5 in the brain alters rims2 protein homeostasis in the cerebellum and hippocampus and exacerbates behavioral deficits after a tbi in mice. |
2024-01-13 |
2024-01-16 |
mouse |
| Kara Snyder, C Edward Dixon, Jeremy Henchir, Kiersten Gorse, Vincent A Vagni, Keri Janesko-Feldman, Patrick M Kochanek, Travis C Jackso. Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice. Experimental neurology. 2024-01-13. PMID:38218585. |
immunoprecipitation and western blot confirmed protein expression of a novel ~170 kda rims2 variant in the cerebellum, and in the hippocampus, it was significantly increased in ko vs wt (p < 0.0001), and in a sex-dependent manner (p = 0.0390). |
2024-01-13 |
2024-01-16 |
mouse |
| Kara Snyder, C Edward Dixon, Jeremy Henchir, Kiersten Gorse, Vincent A Vagni, Keri Janesko-Feldman, Patrick M Kochanek, Travis C Jackso. Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice. Experimental neurology. 2024-01-13. PMID:38218585. |
furthermore, male kos had decreased total canonical rims2 levels in the cerebellum (p = 0.0027) and hippocampus (p < 0.0001), whereas female kos had increased total rims1 levels in the cerebellum (p = 0.0389). |
2024-01-13 |
2024-01-16 |
mouse |
| Laura Ferré-González, Ángel Balaguer, Marta Roca, Artemis Ftara, Ana Lloret, Consuelo Cháfer-Pericá. Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease. Scientific reports. vol 14. issue 1. 2024-01-09. PMID:38195731. |
this work aims to perform a lipidomic study in selected brain areas (cerebellum, amygdala, hippocampus, entire cortex) from wild-type (wt, n = 10) and appswe/ps1de9 transgenic (tg, n = 10) female mice of 5 months of age, as a model of early ad, to identify alterations in lipid composition. |
2024-01-09 |
2024-01-13 |
mouse |
| Naglaa Z H Eleiwa, Alaa S F Elsayed, Enas N Said, Mohamed M M Metwally, Yasmina M Abd-Elhaki. Di (2-ethylhexyl) phthalate alters neurobehavioral responses and oxidative status, architecture, and GFAP and BDNF signaling in juvenile rat's brain: Protective role of Coenzyme10. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-12-19. PMID:38113957. |
also, the increased immunoexpression of brain-derived neurotrophic factor, not glial fibrillary acidic protein, in the cerebral, hippocampal, and cerebellar brain tissues due to dehp exposure was alleviated with cq10. |
2023-12-19 |
2023-12-23 |
human |
| Anna M Fiorito, Eric Fakra, Guillaume Sescousse, El Chérif Ibrahim, Romain Re. Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophrenia. Translational psychiatry. vol 13. issue 1. 2023-12-13. PMID:38092734. |
we report evidence of a widespread transcriptional alteration of microglia genes both in brain tissues (we observed a decreased expression in the cerebellum, associative striatum, hippocampus, and parietal cortex of individuals with schizophrenia compared with healthy controls) and whole blood (characterized by a mixed altered expression pattern). |
2023-12-13 |
2023-12-17 |
human |