| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jung-Wan Cho, Sun-Young Jung, Sang-Won Lee, Sam-Jun Lee, Tae-Beom Seo, Young-Pyo Kim, Dae-Young Ki. Treadmill exercise ameliorates social isolation-induced depression through neuronal generation in rat pups. Journal of exercise rehabilitation. vol 13. issue 6. 2020-09-30. PMID:29326893. |
we examined the expression of 5-hydroxytryptamine (5-ht) and tryptophan hydroxylase (tph) in the dorsal raphe using immunofluorescence. |
2020-09-30 |
2023-08-13 |
rat |
| Jung-Wan Cho, Sun-Young Jung, Sang-Won Lee, Sam-Jun Lee, Tae-Beom Seo, Young-Pyo Kim, Dae-Young Ki. Treadmill exercise ameliorates social isolation-induced depression through neuronal generation in rat pups. Journal of exercise rehabilitation. vol 13. issue 6. 2020-09-30. PMID:29326893. |
expression of 5-ht and tph in the dorsal raphe and expression of bdnf and trkb in the hippocampus were decreased by social isolation. |
2020-09-30 |
2023-08-13 |
rat |
| Jonathan M Borku. Harnessing migraines for neural regeneration. Neural regeneration research. vol 13. issue 4. 2020-09-30. PMID:29722303. |
in this paper, key components of migraine are reviewed - neurogenic inflammation with release of calcitonin gene-related peptide (cgrp) and substance p, plasma protein extravasation, platelet activation, release of serotonin by platelets and likely by the dorsal raphe nucleus, activation of endothelial nitric oxide synthase (enos), production of brain-derived neurotrophic factor (bdnf) and, in migraine aura, cortical spreading depression - along with their potential neurorestorative aspects. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yong Li, Qian Jiao, Xixun Du, Mingxia Bi, Shuaishuai Han, Lingling Jiao, Hong Jian. Investigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135645. |
although there was no obvious change in the number of 5-htergic neurons in the dorsal raphe nucleus after pcpa treatment, the levels of 5-ht and its metabolite in the frontal cortex and hippocampus were reduced, respectively. |
2020-09-30 |
2023-08-13 |
mouse |
| Motohiro Okada, Kouji Fukuyama, Ruri Okubo, Takashi Shiroyama, Yuto Ued. Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus. Pharmaceuticals (Basel, Switzerland). vol 12. issue 4. 2020-09-30. PMID:31590422. |
following systemic and local administrations of lurasidone, mk801 and 5-ht receptor modulators, we determined releases of 5-ht in dorsal raphe nucleus (drn), mediodorsal thalamic nucleus (mdtn) and medial prefrontal cortex (mpfc) and γ-aminobutyric acid (gaba) in drn using multiprobe microdialysis with ultra-high-performance liquid chromatography (uhplc). |
2020-09-30 |
2023-08-13 |
Not clear |
| Yassine Ait Bali, Saadia Ba-Mhamed, Mohamed Benni. Behavioral and Immunohistochemical Study of the Effects of Subchronic and Chronic Exposure to Glyphosate in Mice. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28848410. |
after completion of the behavioral testing, adult mice were sacrificed and the expression of tyrosine hydroxylase (th) in the substantia nigra pars compacta (snc) and serotonin (5-ht) in the dorsal raphe nucleus (drn), the basolateral amygdala (bla) and the ventral medial prefrontal cortex (mpfc) was evaluated using immunohistochemical procedure. |
2020-09-29 |
2023-08-13 |
mouse |
| Patrick A Forcell. Serotonin in the Dorsal Raphe: As I Live and Breathe. Epilepsy currents. vol 18. issue 3. 2020-09-29. PMID:29950948. |
serotonin in the dorsal raphe: as i live and breathe. |
2020-09-29 |
2023-08-13 |
Not clear |
| Shunpei Moriya, Akira Yamashita, Ryusei Nishi, Yoko Ikoma, Akihiro Yamanaka, Tomoyuki Kuwak. Acute nociceptive stimuli rapidly induce the activity of serotonin and noradrenalin neurons in the brain stem of awake mice. IBRO reports. vol 7. 2020-09-29. PMID:31194165. |
most 5-ht neurons in the dorsal raphe (dr) have ascending projections rather than descending projections, and they project to the thalamus that modulates nociception. |
2020-09-29 |
2023-08-13 |
mouse |
| Gina L Forster, Eden M Anderson, Jamie L Scholl, Jodi L Lukkes, Michael J Wat. Negative consequences of early-life adversity on substance use as mediated by corticotropin-releasing factor modulation of serotonin activity. Neurobiology of stress. vol 9. 2020-09-28. PMID:30151419. |
an introduction to the corticotropin-releasing factor (crf) and serotonin systems, their development and their interactions at the level of the dorsal raphe will be provided, illustrating how this particular stress system is sexually dimorphic, and is well positioned to be affected by stressors early in development and throughout maturation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Gina L Forster, Eden M Anderson, Jamie L Scholl, Jodi L Lukkes, Michael J Wat. Negative consequences of early-life adversity on substance use as mediated by corticotropin-releasing factor modulation of serotonin activity. Neurobiology of stress. vol 9. 2020-09-28. PMID:30151419. |
moreover, it is important to clarify whether similar neurobiological mechanisms exist for males and females, given the sexual dimorphism both in crf receptors and serotonin indices in the dorsal raphe and in the behavioral outcomes of early-life adversity. |
2020-09-28 |
2023-08-13 |
Not clear |
| Sang-Seo Park, Hye-Sang Park, Tae-Woon Kim, Sam-Jun Le. Effects of swimming exercise on social isolation-induced memory impairment and apoptosis in old rats. Journal of exercise rehabilitation. vol 16. issue 3. 2020-09-28. PMID:32724780. |
immunohistochemistry for tryptophan hydroxylase (tph) and 5-ht in the dorsal raphe and for doublecortin (dcx) in the hippocampal dentate gyrus was conducted. |
2020-09-28 |
2023-08-13 |
rat |
| Naoya Nishitani, Yu Ohmura, Kazuki Nagayasu, Norihiro Shibui, Shuji Kaneko, Akiko Ohashi, Takayuki Yoshida, Akihiro Yamanaka, Mitsuhiro Yoshiok. CRISPR/Cas9-mediated in vivo gene editing reveals that neuronal 5-HT Brain research. vol 1719. 2020-09-25. PMID:31194947. |
injection of the viral vector into the dorsal raphe nucleus (drn) of cre-dependent cas9 knock-in mice induced cre-dependent cas9 expression mainly in drn serotonin and gaba neurons. |
2020-09-25 |
2023-08-13 |
mouse |
| Sang-Seo Park, Hey-Sang Park, Chang-Ju Kim, Seung-Soo Baek, Tae-Woon Ki. Exercise attenuates maternal separation-induced mood disorder-like behaviors by enhancing mitochondrial functions and neuroplasticity in the dorsal raphe. Behavioural brain research. vol 372. 2020-09-10. PMID:31229645. |
serotonin deficits and mitochondrial dysfunction in the dorsal raphe may underlie mood disorders such as anxiety and depression. |
2020-09-10 |
2023-08-13 |
Not clear |
| Sang-Seo Park, Hey-Sang Park, Chang-Ju Kim, Seung-Soo Baek, Tae-Woon Ki. Exercise attenuates maternal separation-induced mood disorder-like behaviors by enhancing mitochondrial functions and neuroplasticity in the dorsal raphe. Behavioural brain research. vol 372. 2020-09-10. PMID:31229645. |
in this study, we investigated the effect of exercise on mitochondrial function, apoptosis, and serotonin levels in the dorsal raphe as well as behavioral changes in cases of maternal separation. |
2020-09-10 |
2023-08-13 |
Not clear |
| Motohiro Okada, Kouji Fukuyama, Tomosuke Nakano, Yuto Ued. Pharmacological Discrimination of Effects of MK801 on Thalamocortical, Mesothalamic, and Mesocortical Transmissions. Biomolecules. vol 9. issue 11. 2020-08-18. PMID:31752219. |
perfusion with mk801 into the dorsal raphe nucleus (drn) decreased gaba release in the drn but selectively increased serotonin release in the mdtn and mpfc. |
2020-08-18 |
2023-08-13 |
Not clear |
| Eric W Prouty, Daniel J Chandler, Wen-Jun Gao, Barry D Waterhous. Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction. The European journal of neuroscience. vol 50. issue 1. 2020-08-14. PMID:30687960. |
glucocorticoids regulate the function of serotonergic neurons in the dorsal raphe nucleus (dr), which are the major source of 5-ht to the forebrain. |
2020-08-14 |
2023-08-13 |
rat |
| Raimundo da Silva Soares, Luiz Luciano Falconi-Sobrinho, Rafael Carvalho Almada, Norberto Cysne Coimbr. Dorsal raphe nucleus 5-Hydroxytryptamine 2A receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced antinociception elicited by the chemical stimulation of superior colliculus neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 7. 2020-08-10. PMID:31227263. |
dorsal raphe nucleus 5-hydroxytryptamine 2a receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced antinociception elicited by the chemical stimulation of superior colliculus neurons. |
2020-08-10 |
2023-08-13 |
Not clear |
| Raimundo da Silva Soares, Luiz Luciano Falconi-Sobrinho, Rafael Carvalho Almada, Norberto Cysne Coimbr. Dorsal raphe nucleus 5-Hydroxytryptamine 2A receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced antinociception elicited by the chemical stimulation of superior colliculus neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 7. 2020-08-10. PMID:31227263. |
however, there is a shortage of studies showing the role of dorsal raphe nucleus (drn) 5-ht |
2020-08-10 |
2023-08-13 |
Not clear |
| Joanna Sowa, Magdalena Kusek, Bartosz Bobula, Grzegorz Hess, Krzysztof Tokarsk. Ketamine Administration Reverses Corticosterone-Induced Alterations in Excitatory and Inhibitory Transmission in the Rat Dorsal Raphe Nucleus. Neural plasticity. vol 2019. 2020-07-29. PMID:31511771. |
however, it is not known if and how ketamine affects the electrophysiological characteristics of neurons and synaptic transmission within the dorsal raphe nucleus (drn), the main source of 5-ht forebrain projections. |
2020-07-29 |
2023-08-13 |
human |
| Danielle A Lopes, Thaissa M O Souza, José S de Andrade, Mariana F S Silva, Hanna K M Antunes, Luciana Le Sueur Maluf, Isabel C Céspedes, Milena B Vian. Anxiolytic and panicolytic-like effects of environmental enrichment seem to be modulated by serotonin neurons located in the dorsal subnucleus of the dorsal raphe. Brain research bulletin. vol 150. 2020-07-24. PMID:31220551. |
anxiolytic and panicolytic-like effects of environmental enrichment seem to be modulated by serotonin neurons located in the dorsal subnucleus of the dorsal raphe. |
2020-07-24 |
2023-08-13 |
rat |