All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
R. Schreiber, J. De Vr. Neuroanatomical basis for the antidepressant-like effects of the 5-HT(1A) receptor agonists 8-OH-DPAT and ipsapirone in the rat forced swimming test. Behavioural pharmacology. vol 4. issue 6. 2019-11-20. PMID:11224231. or local application into the dorsal raphe nucleus (drn), a brain area rich in presynaptic 5-ht(1a) receptors, resulted in a parallel shift of the dose-response curve to the left (id(50) 5.1 and 3.9µg/rat, respectively). 2019-11-20 2023-08-12 rat
Constantino Sotelo, Béatrice Cholley, Salah El Mestikawy, Henri Gozlan, Michel Hamo. Direct Immunohistochemical Evidence of the Existence of 5-HT1A Autoreceptors on Serotoninergic Neurons in the Midbrain Raphe Nuclei. The European journal of neuroscience. vol 2. issue 12. 2019-11-20. PMID:12106075. double immunohistochemical staining using the anti-5-ht1a receptor antibodies and an anti-serotonin (5-ht) antiserum showed that all the 5-ht1a receptor immunoreactive neurons in the dorsal raphe, and the vast majority of them in the median raphe, are serotoninergic neurons. 2019-11-20 2023-08-12 Not clear
Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. 2019-11-20 2023-08-13 mouse
Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. the onset of antidepressant effects also coincides with desensitization of somatodendritic serotonin autoreceptors in the dorsal raphe nucleus (drn), suggesting that disrupting inhibitory feedback within the serotonin system may contribute to the therapeutic effects of ssris. 2019-11-20 2023-08-13 mouse
Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. in this work, stimulations of the dorsal raphe nucleus (drn) evoke serotonin release that is recorded in the substantia nigra pars reticulata (snpr) using in vivo fast-scan cyclic voltammetry. 2019-11-20 2023-08-13 mouse
Wenjie Zhou, Yan Jin, Qian Meng, Xia Zhu, Tongjian Bai, Yanghua Tian, Yu Mao, Likui Wang, Wen Xie, Hui Zhong, Na Zhang, Min-Hua Luo, Wenjuan Tao, Haitao Wang, Jie Li, Juan Li, Ben-Sheng Qiu, Jiang-Ning Zhou, Xiangyao Li, Han Xu, Kai Wang, Xiaochu Zhang, Yong Liu, Gal Richter-Levin, Lin Xu, Zhi Zhan. A neural circuit for comorbid depressive symptoms in chronic pain. Nature neuroscience. vol 22. issue 10. 2019-11-05. PMID:31451801. here we identify a novel pathway involving 5-hydroxytryptamine (5-ht) projections from the dorsal raphe nucleus (5-ht 2019-11-05 2023-08-13 Not clear
Ayesha Sengupta, Andrew Holme. A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory. Neuron. vol 103. issue 3. 2019-10-31. PMID:31204082. a discrete dorsal raphe to basal amygdala 5-ht circuit calibrates aversive memory. 2019-10-31 2023-08-13 Not clear
Ayesha Sengupta, Andrew Holme. A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory. Neuron. vol 103. issue 3. 2019-10-31. PMID:31204082. using convergent anatomical and functional approaches, we interrogate the contribution to fear of basal amygdala (ba) 5-ht inputs from the dorsal raphe nucleus (drn). 2019-10-31 2023-08-13 Not clear
Michael V Baratta, Nathan R Leslie, Isabella P Fallon, Samuel D Dolzani, Lauren E Chun, Andrew M Tamalunas, Linda R Watkins, Steven F Maie. Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females. The European journal of neuroscience. vol 47. issue 8. 2019-10-30. PMID:29359831. in separate experiments, behavioural (juvenile social exploration, fear and shuttle box escape) and neurochemical (activation of dorsal raphe serotonin and dorsal raphe-projecting prelimbic neurons) outcomes, which are sensitive to the dimension of control in males, were assessed. 2019-10-30 2023-08-13 rat
Hui-Ai Zhang, Nan Sang, Xian Ge, Qian Huang, Xue-Liang Li, Jie Sh. Nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-HT neurons in male maternally separated rats. Scientific reports. vol 8. issue 1. 2019-10-10. PMID:29921870. nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-ht neurons in male maternally separated rats. 2019-10-10 2023-08-13 rat
Hui-Ai Zhang, Nan Sang, Xian Ge, Qian Huang, Xue-Liang Li, Jie Sh. Nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-HT neurons in male maternally separated rats. Scientific reports. vol 8. issue 1. 2019-10-10. PMID:29921870. nesfatin-1, a satiety molecule processed from nucleobindin2 (nucb2), is implicated in visceral hypersensitivity in rats and colocalized with 5-hydroxytryptamine (5-ht) in the dorsal raphe nucleus (drn). 2019-10-10 2023-08-13 rat
Honghai Zhang, Haiting Zhao, Chang Zeng, Christa Van Dort, Carl L Faingold, Norman E Taylor, Ken Solt, Hua-Jun Fen. Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. Neurobiology of disease. vol 110. 2019-09-06. PMID:29141182. optogenetic activation of 5-ht neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the dba/1 mouse sudep model. 2019-09-06 2023-08-13 mouse
Honghai Zhang, Haiting Zhao, Chang Zeng, Christa Van Dort, Carl L Faingold, Norman E Taylor, Ken Solt, Hua-Jun Fen. Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. Neurobiology of disease. vol 110. 2019-09-06. PMID:29141182. we hypothesized that the dorsal raphe (dr), which sends 5-ht projections to the forebrain, is implicated in s-ira. 2019-09-06 2023-08-13 mouse
Haiyan Li, Chihiro Ishikawa, Takashi Shig. Effects of postnatal handling on adult behavior and brain mRNA expression of serotonin receptor, brain-derived neurotrophic factor and GABA-A receptor subunit. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 68. 2019-08-06. PMID:29678562. next, to elucidate mechanisms underlying the behavioral effects, we evaluated mrna expression of the serotonin 1a (5-ht1a) receptor, brain-derived neurotrophic factor (bdnf), and gaba-a receptor subunits in the medial prefrontal cortex, amygdala, dorsal and ventral hippocampi, and dorsal raphe nucleus by quantitative rt-pcr, since these genes and brain regions have been shown to be involved in cognition and emotion. 2019-08-06 2023-08-13 mouse
Changwoo Seo, Akash Guru, Michelle Jin, Brendan Ito, Brianna J Sleezer, Yi-Yun Ho, Elias Wang, Christina Boada, Nicholas A Krupa, Durgaprasad S Kullakanda, Cynthia X Shen, Melissa R Warde. Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. Science (New York, N.Y.). vol 363. issue 6426. 2019-08-01. PMID:30705194. intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. 2019-08-01 2023-08-13 mouse
Changwoo Seo, Akash Guru, Michelle Jin, Brendan Ito, Brianna J Sleezer, Yi-Yun Ho, Elias Wang, Christina Boada, Nicholas A Krupa, Durgaprasad S Kullakanda, Cynthia X Shen, Melissa R Warde. Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. Science (New York, N.Y.). vol 363. issue 6426. 2019-08-01. PMID:30705194. in mice, we found that stimulation of dorsal raphe serotonin neurons suppressed movement in low- and moderate-threat environments but induced escape behavior in high-threat environments, and that movement-related dorsal raphe serotonin neural dynamics inverted in high-threat environments. 2019-08-01 2023-08-13 mouse
Tomoaki M Kato, Mie Kubota-Sakashita, Noriko Fujimori-Tonou, Fumihito Saitow, Satoshi Fuke, Akira Masuda, Shigeyoshi Itohara, Hidenori Suzuki, Tadafumi Kat. Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder. Molecular psychiatry. vol 23. issue 10. 2019-07-31. PMID:29892051. dorsal raphe neurons in the heterozygous cko showed hyperexcitability, along with enhanced serotonin turnover in the nucleus accumbens and upregulation of maob in dorsal raphe. 2019-07-31 2023-08-13 mouse
Thomas R Barber, Ludovica Griffanti, Kinan Muhammed, Daniel S Drew, Kevin M Bradley, Daniel R McGowan, Marie Crabbe, Christine Lo, Clare E Mackay, Masud Husain, Michele T Hu, Johannes C Klei. Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. Brain : a journal of neurology. vol 141. issue 10. 2019-07-05. PMID:30212839. apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. 2019-07-05 2023-08-13 Not clear
Danilo De Gregorio, Ryan J McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobb. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. vol 160. issue 1. 2019-06-26. PMID:30157131. increasing doses of cbd (0.1-1.0 mg/kg) decreased the firing rate of 5-ht neurons in the dorsal raphe nucleus, which was prevented by administration of the 5-ht1a antagonist way 100635 (0.3 mg/kg, i.v.) 2019-06-26 2023-08-13 rat
Sachie K Ogawa, Mitsuko Watabe-Uchid. Organization of dopamine and serotonin system: Anatomical and functional mapping of monosynaptic inputs using rabies virus. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:28476484. there is surprising similarity between the input to dopamine neurons in the ventral tegmental area (vta) and the input to serotonin neurons in the dorsal raphe (dr), suggesting functional interactions between these systems. 2019-06-24 2023-08-13 Not clear