| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danilo De Gregorio, Ryan J McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobb. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. vol 160. issue 1. 2019-06-26. PMID:30157131. |
increasing doses of cbd (0.1-1.0 mg/kg) decreased the firing rate of 5-ht neurons in the dorsal raphe nucleus, which was prevented by administration of the 5-ht1a antagonist way 100635 (0.3 mg/kg, i.v.) |
2019-06-26 |
2023-08-13 |
rat |
| Sachie K Ogawa, Mitsuko Watabe-Uchid. Organization of dopamine and serotonin system: Anatomical and functional mapping of monosynaptic inputs using rabies virus. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:28476484. |
there is surprising similarity between the input to dopamine neurons in the ventral tegmental area (vta) and the input to serotonin neurons in the dorsal raphe (dr), suggesting functional interactions between these systems. |
2019-06-24 |
2023-08-13 |
Not clear |
| Jing Ren, Drew Friedmann, Jing Xiong, Cindy D Liu, Brielle R Ferguson, Tanya Weerakkody, Katherine E DeLoach, Chen Ran, Albert Pun, Yanwen Sun, Brandon Weissbourd, Rachael L Neve, John Huguenard, Mark A Horowitz, Liqun Lu. Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems. Cell. vol 175. issue 2. 2019-06-14. PMID:30146164. |
anatomically defined and functionally distinct dorsal raphe serotonin sub-systems. |
2019-06-14 |
2023-08-13 |
Not clear |
| Naoshige Uchida, Jeremiah Y Cohe. Slow motion. eLife. vol 6. 2019-05-31. PMID:28193318. |
optogenetic stimulation of serotonin neurons in the dorsal raphe causes mice to move more slowly without causing any apparent motor deficits or anxiety-like effects. |
2019-05-31 |
2023-08-13 |
mouse |
| Haleigh R Smith, Nicole K Leibold, Daniel A Rappoport, Callie M Ginapp, Benton S Purnell, Nicole M Bode, Stephanie L Alberico, Young-Cho Kim, Enrica Audero, Cornelius T Gross, Gordon F Buchana. Dorsal Raphe Serotonin Neurons Mediate CO The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29378860. |
dorsal raphe serotonin neurons mediate co arousal from sleep in response to co |
2019-05-20 |
2023-08-13 |
Not clear |
| Haruko Kinoshita, Naoya Nishitani, Yuma Nagai, Chihiro Andoh, Nozomi Asaoka, Hiroyuki Kawai, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Ketamine-Induced Prefrontal Serotonin Release Is Mediated by Cholinergic Neurons in the Pedunculopontine Tegmental Nucleus. The international journal of neuropsychopharmacology. vol 21. issue 3. 2019-04-18. PMID:29370396. |
although α4β2 nicotinic acetylcholine receptor (α4β2 nachr) in the dorsal raphe nucleus plays a key role in the ketamine-induced prefrontal serotonin release, the source of cholinergic afferents, and its role is unclear. |
2019-04-18 |
2023-08-13 |
mouse |
| Raimundo da Silva Soares, Luiz Luciano Falconi-Sobrinho, Tayllon Dos Anjos-Garcia, Norberto Cysne Coimbr. 5-Hydroxytryptamine 2A receptors of the dorsal raphe nucleus modulate panic-like behaviours and mediate fear-induced antinociception elicited by neuronal activation in the central nucleus of the inferior colliculus. Behavioural brain research. vol 357-358. 2019-03-29. PMID:28736332. |
5-hydroxytryptamine 2a receptors of the dorsal raphe nucleus modulate panic-like behaviours and mediate fear-induced antinociception elicited by neuronal activation in the central nucleus of the inferior colliculus. |
2019-03-29 |
2023-08-13 |
Not clear |
| Glenda Viggiano Campos, Sylvana Rendeiro de Noronha, Aline Arlindo de Souza, Paulo Marcelo Lima, Aline Rezende Abreu, Deoclecio Chianca-Jr, Rodrigo Cunha de Meneze. Estrogen receptor β activation within dorsal raphe nucleus reverses anxiety-like behavior induced by food restriction in female rats. Behavioural brain research. vol 357-358. 2019-03-29. PMID:29567265. |
estrogen receptors, mainly erβ type, are commonly found in the dorsal raphe nucleus (drn) neurons, an important nucleus related to anxiety modulation and the primary source of serotonin (5-ht) in the brain. |
2019-03-29 |
2023-08-13 |
rat |
| Roberta Monteiro Incrocci, Franciely Paliarin, Manoel Jorge Nobr. Prelimbic NMDA receptors stimulation mimics the attenuating effects of clozapine on the auditory electrophysiological rebound induced by ketamine withdrawal. Neurotoxicology. vol 69. 2019-03-15. PMID:30170016. |
these data suggest that the long-term ket treatment disrupts the collicular auditory field potentials, possibly through influencing prl glutamate activity on intrinsic 5-ht mechanisms in the dorsal raphe and cic. |
2019-03-15 |
2023-08-13 |
rat |
| Jessica J Walsh, Daniel J Christoffel, Boris D Heifets, Gabriel A Ben-Dor, Aslihan Selimbeyoglu, Lin W Hung, Karl Deisseroth, Robert C Malenk. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. vol 560. issue 7720. 2019-03-04. PMID:30089910. |
here we show in mice that bidirectional modulation of the release of serotonin (5-ht) from dorsal raphe neurons in the nucleus accumbens bidirectionally modifies sociability. |
2019-03-04 |
2023-08-13 |
mouse |
| Jessica J Walsh, Daniel J Christoffel, Boris D Heifets, Gabriel A Ben-Dor, Aslihan Selimbeyoglu, Lin W Hung, Karl Deisseroth, Robert C Malenk. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. vol 560. issue 7720. 2019-03-04. PMID:30089910. |
in a mouse model of a common genetic cause of autism spectrum disorder-a copy number variation on chromosome 16p11.2-genetic deletion of the syntenic region from 5-ht neurons induces deficits in social behaviour and decreases dorsal raphe 5-ht neuronal activity. |
2019-03-04 |
2023-08-13 |
mouse |
| Jessica J Walsh, Daniel J Christoffel, Boris D Heifets, Gabriel A Ben-Dor, Aslihan Selimbeyoglu, Lin W Hung, Karl Deisseroth, Robert C Malenk. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. vol 560. issue 7720. 2019-03-04. PMID:30089910. |
these sociability deficits can be rescued by optogenetic activation of dorsal raphe 5-ht neurons, an effect requiring and mimicked by activation of 5-ht1b receptors in the nucleus accumbens. |
2019-03-04 |
2023-08-13 |
mouse |
| Daniel G Ehlinger, Kathryn G Common. Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons. Neuropharmacology. vol 144. 2019-03-04. PMID:30176250. |
we utilized a temporally controlled and 5-ht neuron specific cacna1c knockout mouse model to assess stress-coping behavior using the forced swim test and dorsal raphe (dr) 5-ht neuron fos activation. |
2019-03-04 |
2023-08-13 |
mouse |
| Hai Zhang, Kuan Li, Hong-Sheng Chen, Shuang-Qi Gao, Zhi-Xuan Xia, Jie-Ting Zhang, Fang Wang, Jian-Guo Che. Dorsal raphe projection inhibits the excitatory inputs on lateral habenula and alleviates depressive behaviors in rats. Brain structure & function. vol 223. issue 5. 2019-02-27. PMID:29460052. |
using retrograde tract tracing with cholera toxin subunit b, we find that dorsal raphe nucleus (drn) sends primary 5-ht projection to the lhb. |
2019-02-27 |
2023-08-13 |
rat |
| Fuzhong Yang, Amy Cheung, Jing Tao, Nan Zhao, Wenbin Wan, Jianhua Shen. Physiological dosages of estradiol and diarylpropionitrile decrease depressive behavior and increase tryptophan hydroxylase expression in the dorsal raphe nucleus of rats subjected to the forced swim test. Neuroreport. vol 30. issue 2. 2019-02-25. PMID:30379725. |
the dorsal raphe nucleus (dr) is a crucial source of serotonin (5-ht) neurons involved in the regulation of stress-induced depression. |
2019-02-25 |
2023-08-13 |
rat |
| Feng Zhai, Fang Shi, Jing Wang, Chun-Fu Dai, Chunsun Fa. Preliminary study on the mechanism underlying the interaction of balance dysfunction and anxiety disorder. Neuroreport. vol 30. issue 2. 2019-02-25. PMID:30571662. |
three days after gt administration, the concentration of norepinephrine (ne) and 5-hydroxyindoleacetic acid (5-hiaa) within medial vestibular nucleus (mvn); the concentration of ne, serotonin (5-ht), and 5-hiaa within locus coeruleus (lc); and the concentration of ne, 5-ht, 5-hiaa, and 3,4-dihydroxyphenylacetic acid within dorsal raphe nucleus (drn) increased significantly compared with the control group. |
2019-02-25 |
2023-08-13 |
rat |
| S D Dolzani, M V Baratta, J M Moss, N L Leslie, S G Tilden, A T Sørensen, L R Watkins, Y Lin, S F Maie. Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29516036. |
ketamine given one week prior to an uncontrollable stressor (inescapable tailshock; is) reduced typical stress-induced activation of the serotonergic (5-ht) dorsal raphe nucleus (drn) and eliminated drn-dependent juvenile social exploration (jse) deficits 24 h after the stressor. |
2019-01-09 |
2023-08-13 |
rat |
| Joanna Sowa, Magdalena Kusek, Marcin Siwiec, Joanna Ewa Sowa, Bartosz Bobula, Krzysztof Tokarski, Grzegorz Hes. The 5-HT Psychopharmacology. vol 235. issue 12. 2019-01-09. PMID:30267130. |
the 5-ht chronic stress and corticosterone have been shown to affect serotonin (5-ht) neurotransmission; however, the influence of stress on the activity of the dorsal raphe nucleus (drn), the main source of 5-ht in the forebrain, is not well understood. |
2019-01-09 |
2023-08-13 |
Not clear |
| Nayara Pestana-Oliveira, Bruna Kalil, Cristiane Mota Leite, Ruither Oliveira Gomes Carolino, Lucas Kniess Debarba, Lucila Leico Kagohara Elias, José Antunes-Rodrigues, Janete A Anselmo-Franc. Effects of Estrogen Therapy on the Serotonergic System in an Animal Model of Perimenopause Induced by 4-Vinylcyclohexen Diepoxide (VCD). eNeuro. vol 5. issue 1. 2019-01-02. PMID:29362726. |
blood was collected for hormone measurement, the brains were removed and dorsal raphe nucleus (drn), hippocampus (hpc), and amygdala (amy) punched out for serotonin (5-ht), estrogen receptor β (erβ), and progesterone receptor (pr) mrna level measurements. |
2019-01-02 |
2023-08-13 |
rat |
| Katsuhiko Miyazaki, Kayoko W Miyazaki, Akihiro Yamanaka, Tomoki Tokuda, Kenji F Tanaka, Kenji Doy. Reward probability and timing uncertainty alter the effect of dorsal raphe serotonin neurons on patience. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29858574. |
reward probability and timing uncertainty alter the effect of dorsal raphe serotonin neurons on patience. |
2018-12-11 |
2023-08-13 |
mouse |