| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julia T Brouard, Judith V Schweimer, Rachel Houlton, Katherine E Burnham, Philip Quérée, Trevor Shar. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:25837696. |
5-hydroxytryptamine (5-ht) neurons in the midbrain dorsal raphe nucleus (drn) are implicated in the drug treatment and pathophysiology of a wide variety of neuropsychiatric disorders. |
2016-04-19 |
2023-08-13 |
rat |
| Pieter Schipper, Dora Lopresto, Roy J Reintjes, Joep Joosten, Marloes J A G Henckens, Tamas Kozicz, Judith R Homber. Improved Stress Control in Serotonin Transporter Knockout Rats: Involvement of the Prefrontal Cortex and Dorsal Raphe Nucleus. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26132384. |
improved stress control in serotonin transporter knockout rats: involvement of the prefrontal cortex and dorsal raphe nucleus. |
2016-04-19 |
2023-08-13 |
rat |
| Vincent Beliveau, Claus Svarer, Vibe G Frokjaer, Gitte M Knudsen, Douglas N Greve, Patrick M Fishe. Functional connectivity of the dorsal and median raphe nuclei at rest. NeuroImage. vol 116. 2016-04-08. PMID:25963733. |
the dorsal raphe (dr) and median raphe (mr) nuclei are the source of most serotonergic neurons projecting throughout the brain and thus provide a compelling target for a seed-based probe of resting-state activity related to 5-ht. |
2016-04-08 |
2023-08-13 |
human |
| Perdita Cheshire, Scott Ayton, Kelly L Bertram, Helen Ling, Abi Li, Catriona McLean, Glenda M Halliday, Sean S O'Sullivan, Tamas Revesz, David I Finkelstein, Elsdon Storey, David R William. Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 6. 2016-04-07. PMID:25649148. |
we obtained brain tissue from 44 pd cases and 17 age-matched controls and assessed monoamine levels and the serotonin and dopamine transporters in the striatum, and the extent of dopaminergic and serotonergic cell preservation in the substantia nigra (sn) and the dorsal raphe nuclei (drn), respectively. |
2016-04-07 |
2023-08-13 |
Not clear |
| Andrea E Corcoran, George B Richerson, Michael B Harri. Functional link between the hypocretin and serotonin systems in the neural control of breathing and central chemosensitivity. Journal of neurophysiology. vol 114. issue 1. 2016-03-28. PMID:25878157. |
recently, a functional interaction was found between the hypocretin system and 5-ht neurons of the dorsal raphe. |
2016-03-28 |
2023-08-13 |
mouse |
| Nozomi Asaoka, Kazuki Nagayasu, Naoya Nishitani, Mayumi Yamashiro, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus. Neuropharmacology. vol 95. 2016-03-24. PMID:25863120. |
olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing gabaergic inhibition via antagonism of 5-ht₆ receptors in the dorsal raphe nucleus. |
2016-03-24 |
2023-08-13 |
mouse |
| Nozomi Asaoka, Kazuki Nagayasu, Naoya Nishitani, Mayumi Yamashiro, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus. Neuropharmacology. vol 95. 2016-03-24. PMID:25863120. |
here, we report that olanzapine enhances the ssri-induced increase in extracellular serotonin (5-ht) levels and antidepressant-like effects by inhibiting gabaergic neurons through 5-ht6 receptor antagonism in the dorsal raphe nucleus (drn). |
2016-03-24 |
2023-08-13 |
mouse |
| Guillaume P Dugué, Magor L Lörincz, Eran Lottem, Enrica Audero, Sara Matias, Patricia A Correia, Clément Léna, Zachary F Maine. Optogenetic recruitment of dorsal raphe serotonergic neurons acutely decreases mechanosensory responsivity in behaving mice. PloS one. vol 9. issue 8. 2016-03-17. PMID:25148042. |
in behaving mice, the photostimulation of dorsal raphe serotonergic neurons produced a rapid and reversible decrease in the animals' responses to plantar stimulation, providing a new level of evidence that serotonin gates sensory-driven responses. |
2016-03-17 |
2023-08-13 |
mouse |
| Kareem S El Iskandrani, Chris A Oosterhof, Mostafa El Mansari, Pierre Blie. Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons. Journal of psychopharmacology (Oxford, England). vol 29. issue 7. 2016-03-11. PMID:25759403. |
although acute (~2 hours) ketamine administration did not affect the mean firing activity of dorsal raphe serotonin and ventral tegmental area dopamine neurons, it did increase that of locus coeruleus norepinephrine neurons. |
2016-03-11 |
2023-08-13 |
rat |
| Sean D Geddes, Saleha Assadzada, Alexandra Sokolovski, Richard Bergeron, Samir Haj-Dahmane, Jean-Claude Béïqu. Time-dependent modulation of glutamate synapses onto 5-HT neurons by antidepressant treatment. Neuropharmacology. vol 95. 2016-03-08. PMID:25747603. |
here, we show that sustained administration of the ssri citalopram leads to a homeostatic-like increase in the strength of excitatory glutamate synapses onto 5-ht neurons of the dorsal raphe nucleus that was apparent following one week of treatment. |
2016-03-08 |
2023-08-13 |
Not clear |
| Toshiharu Tazawa, Yoshinori Kamiya, Ayako Kobayashi, Kensuke Saeki, Masahito Takiguchi, Yusuke Nakahashi, Hironobu Shinbori, Kengo Funakoshi, Takahisa Got. Spinal cord stimulation modulates supraspinal centers of the descending antinociceptive system in rats with unilateral spinal nerve injury. Molecular pain. vol 11. 2016-03-08. PMID:26104415. |
the nucleus raphe magnus (nrm) in the rostral ventromedial medulla is a major source of serotonin [5-hydroxytryptamine (5-ht)] to the das, but the role of the dorsal raphe nucleus (drn) in the ventral periaqueductal gray matter is still unclear. |
2016-03-08 |
2023-08-13 |
rat |
| Boris Mlinar, Alberto Montalbano, Gilda Baccini, Francesca Tatini, Rolando Berlinguer Palmini, Renato Corradett. Nonexocytotic serotonin release tonically suppresses serotonergic neuron activity. The Journal of general physiology. vol 145. issue 3. 2016-03-04. PMID:25712017. |
using an electrophysiological approach in a slice preparation, we show that, in the dorsal raphe nucleus (drn), continuous nonexocytotic 5-ht release is responsible for suppression of phenylephrine-facilitated serotonergic neuron firing under basal conditions as well as for autoinhibition induced by ssri application. |
2016-03-04 |
2023-08-13 |
Not clear |
| Andras David Nagy, Ayaka Iwamoto, Misato Kawai, Ryosei Goda, Haruka Matsuo, Tsuyoshi Otsuka, Mao Nagasawa, Mitsuhiro Furuse, Shinobu Yasu. Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder. Chronobiology international. vol 32. issue 4. 2016-02-16. PMID:25515595. |
melatonin treatments altered the expression of genes of serotonergic neurotransmission in the dorsal raphe (tph2, sert, vmat2 and 5ht1a) and serotonin contents in the amygdala. |
2016-02-16 |
2023-08-13 |
mouse |
| Yan Jin, Bin Luo, Yan-Yan Su, Xin-Xing Wang, Liang Chen, Ming Wang, Wei-Wen Wang, Lin Che. Sodium salicylate suppresses GABAergic inhibitory activity in neurons of rodent dorsal raphe nucleus. PloS one. vol 10. issue 5. 2016-02-03. PMID:25962147. |
sodium salicylate (nasal), a tinnitus inducing agent, can activate serotonergic (5-htergic) neurons in the dorsal raphe nucleus (drn) and can increase serotonin (5-ht) level in the inferior colliculus and the auditory cortex in rodents. |
2016-02-03 |
2023-08-13 |
mouse |
| Fatemeh Keshavarzy, Chantal Bonnet, Gila Behzadi, Gila Bezhadi, Raymond Cespugli. Expression patterns of c-Fos early gene and phosphorylated ERK in the rat brain following 1-h immobilization stress: concomitant changes induced in association with stress-related sleep rebound. Brain structure & function. vol 220. issue 3. 2016-01-27. PMID:24567082. |
during the restraint, serotonin released by the dorsal raphe nucleus within the arcuate area stimulates the availability of corticotropin-like intermediate lobe peptide (clip or acth18-39). |
2016-01-27 |
2023-08-12 |
rat |
| Ran Ye, Meagan A Quinlan, Hideki Iwamoto, Hsiao-Huei Wu, Noah H Green, Christopher S Jetter, Douglas G McMahon, Jeremy Veestra-VanderWeele, Pat Levitt, Randy D Blakel. Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters. Frontiers in synaptic neuroscience. vol 7. 2016-01-21. PMID:26793096. |
additionally, dorsal raphe 5-ht neurons from nlgn2 null mice exhibit reduced excitability, a loss of gabaa receptor-mediated ipscs, and increased 5-ht1a autoreceptor sensitivity. |
2016-01-21 |
2023-08-13 |
mouse |
| C Bétry, D Overstreet, N Haddjeri, A L Pehrson, C Bundgaard, C Sanchez, A Mør. A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25697477. |
the effects of an acute intravenous administration of each compound alone and in combination were evaluated with respect to 5-ht neuronal firing rate in the dorsal raphe nucleus (drn). |
2016-01-15 |
2023-08-13 |
rat |
| Chris A Oosterhof, Mostafa El Mansari, Pierre Blie. Asenapine alters the activity of monoaminergic systems following its subacute and long-term administration: an in vivo electrophysiological characterization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 4. 2016-01-11. PMID:25656272. |
in the dorsal raphe nucleus, asenapine increased the firing rate of 5-ht neurons after two, but not 21 days of administration. |
2016-01-11 |
2023-08-13 |
Not clear |
| Nicholas J Jury, Betsy A McCormick, Nelson D Horseman, Stephen C Benoit, Karen A Gregerso. Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation. PloS one. vol 10. issue 2. 2016-01-11. PMID:25689282. |
lactating mice exhibited lower immunoreactive 5-ht and intensity in the dorsal raphe nucleus when compared with nulliparous controls. |
2016-01-11 |
2023-08-13 |
mouse |
| Caryne P Craige, Stacia Lewandowski, Lynn G Kirby, Ellen M Unterwal. Dorsal raphe 5-HT(2C) receptor and GABA networks regulate anxiety produced by cocaine withdrawal. Neuropharmacology. vol 93. 2016-01-01. PMID:25656481. |
dorsal raphe 5-ht(2c) receptor and gaba networks regulate anxiety produced by cocaine withdrawal. |
2016-01-01 |
2023-08-13 |
mouse |