All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Francis Rodriguez Bambico, Tommaso Cassano, Sergio Dominguez-Lopez, Noam Katz, Claire Dominique Walker, Daniele Piomelli, Gabriella Gobb. Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 10. 2010-12-06. PMID:20571484. electrophysiological recordings revealed a marked 34.68% increase in dorsal raphe 5-ht neural firing that was reversed by rimonabant in a subset of neurons exhibiting high firing rates (33.15% mean decrease). 2010-12-06 2023-08-12 mouse
Noam S Katz, Bruno P Guiard, Mostafa El Mansari, Pierre Blie. Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. Journal of psychopharmacology (Oxford, England). vol 24. issue 8. 2010-12-02. PMID:19939862. a significant increase in dorsal raphe nucleus 5-ht neuronal firing was seen after a two-day regimen, and remained elevated after 14 days. 2010-12-02 2023-08-12 rat
Noam S Katz, Bruno P Guiard, Mostafa El Mansari, Pierre Blie. Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. Journal of psychopharmacology (Oxford, England). vol 24. issue 8. 2010-12-02. PMID:19939862. desensitization of the 5-ht(1a) receptor on 5-ht neurons of the dorsal raphe nucleus occurred after two days of nomifensine administration. 2010-12-02 2023-08-12 rat
Mohammad Charkhpour, Ali Reza Mohajjel Nayebi, Yousef Doustar, Kambiz Hassanzade. 8-OH-DPAT prevents morphine-induced apoptosis in rat dorsal raphe nucleus: a possible mechanism for attenuating morphine tolerance. Anesthesia and analgesia. vol 111. issue 5. 2010-11-16. PMID:20736434. previously, we found that activation of serotonin 1a (5-ht1a) receptors in the dorsal raphe nucleus (drn) decreased the development of tolerance to the analgesic effect of morphine. 2010-11-16 2023-08-12 rat
Eugene Oh, Takashi Maejima, Chen Liu, Evan Deneris, Stefan Herlitz. Substitution of 5-HT1A receptor signaling by a light-activated G protein-coupled receptor. The Journal of biological chemistry. vol 285. issue 40. 2010-10-26. PMID:20643652. finally, rh-ct(5-ht1a) is able to rescue 5-ht(1a) signaling of 5-ht(1a) ko mice in cultured neurons and in slices of the dorsal raphe showing that rh-ct(5-ht1a) is able to functionally compensate for native 5-ht(1a). 2010-10-26 2023-08-12 mouse
Tatiana Longo Borges Miguel, Roger Luis Henschel Pobbe, Ailton Spiacci Junior, Hélio Zangrossi Junio. Dorsal raphe nucleus regulation of a panic-like defensive behavior evoked by chemical stimulation of the rat dorsal periaqueductal gray matter. Behavioural brain research. vol 213. issue 2. 2010-10-19. PMID:20451559. in this study we evaluated the effects of the pharmacological manipulation of the dorsal raphe nucleus (drn), which are the main source of 5-ht input to the dpag, on the escape response evoked in rats by the intra-dpag injection of the nitric oxide donor sin-1. 2010-10-19 2023-08-12 rat
Wenyu Fu, Erwan Le Maître, Veronique Fabre, Jean-Francois Bernard, Zhi-Qing David Xu, Tomas Hökfel. Chemical neuroanatomy of the dorsal raphe nucleus and adjacent structures of the mouse brain. The Journal of comparative neurology. vol 518. issue 17. 2010-10-08. PMID:20589909. here we studied, with histochemical techniques, the relation between serotonin, some other small-molecule transmitters, and a number of neuropeptides in the dorsal raphe nucleus (drn) and the adjacent ventral periaqueductal gray (vpag) of mouse, an important question being to establish possible differences from rat. 2010-10-08 2023-08-12 mouse
María Carmen Fernández-Galaz, Teresa Fernández-Agulló, Jose María Carrascosa, Manuel Ros, Luis M Garcia-Segur. Leptin accumulation in hypothalamic and dorsal raphe neurons is inversely correlated with brain serotonin content. Brain research. vol 1329. 2010-09-28. PMID:20211152. leptin accumulation in hypothalamic and dorsal raphe neurons is inversely correlated with brain serotonin content. 2010-09-28 2023-08-12 rat
María Carmen Fernández-Galaz, Teresa Fernández-Agulló, Jose María Carrascosa, Manuel Ros, Luis M Garcia-Segur. Leptin accumulation in hypothalamic and dorsal raphe neurons is inversely correlated with brain serotonin content. Brain research. vol 1329. 2010-09-28. PMID:20211152. these findings indicate that serotonin regulates leptin uptake by neuronal cell bodies of the dorsal raphe and hypothalamus, this suggests that at least part of the effects of serotonin may be mediated by the regulation of neuronal trafficking in the brain. 2010-09-28 2023-08-12 rat
B M Ruf, Z Bhagwaga. The 5-HT1B receptor: a novel target for the pathophysiology of depression. Current drug targets. vol 10. issue 11. 2010-09-27. PMID:19702551. rats predisposed to learned helplessness have exhibited downregulation of 5-ht(1b) receptor messenger ribonucleic acid (mrna) in dorsal raphe nucleus (drn). 2010-09-27 2023-08-12 rat
Bruno P Guiard, Mostafa El Mansari, Pierre Blie. Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors. Current drug targets. vol 10. issue 11. 2010-09-27. PMID:19702555. indeed, it is well established that the increase in central dopaminergic transmission regulates the neuronal activity of 5-ht and ne in the dorsal raphe (dr) and locus coeruleus (lc), respectively, while in turn, the ventral tegmental area (vta), is sensitive to changes in 5-ht and ne release. 2010-09-27 2023-08-12 Not clear
Roger Luis Henschel Pobbe, Helio Zangross. The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matter. Neuroscience letters. vol 479. issue 2. 2010-09-27. PMID:20478359. the dpag in the midbrain, which is innervated by 5-ht fibers originating from the dorsal raphe nucleus (drn), has been consistently implicated in the genesis/regulation of anxiety- and fear-related defensive responses. 2010-09-27 2023-08-12 rat
Patricia Bonnavion, Jean-François Bernard, Michel Hamon, Joëlle Adrien, Veronique Fabr. Heterogeneous distribution of the serotonin 5-HT(1A) receptor mRNA in chemically identified neurons of the mouse rostral brainstem: Implications for the role of serotonin in the regulation of wakefulness and REM sleep. The Journal of comparative neurology. vol 518. issue 14. 2010-09-16. PMID:20506474. 5-ht(1a)r mrna was found in most 5-ht neurons in the dorsal raphe (dr), the median raphe (mnr), the b9, and the interpeduncular (ip) nuclei. 2010-09-16 2023-08-12 mouse
F B Lima, C L Bethe. Ovarian steroids decrease DNA fragmentation in the serotonin neurons of non-injured rhesus macaques. Molecular psychiatry. vol 15. issue 6. 2010-09-07. PMID:19823180. we previously found that ovarian steroids promote neuroprotection in serotonin neurons by decreasing the expression of pro-apoptotic genes and proteins in the dorsal raphe nucleus of rhesus macaques, even in the absence of overt injury. 2010-09-07 2023-08-12 monkey
Jean Mazella, Olivier Pétrault, Guillaume Lucas, Emmanuel Deval, Sophie Béraud-Dufour, Carine Gandin, Malika El-Yacoubi, Catherine Widmann, Alice Guyon, Eric Chevet, Said Taouji, Grégory Conductier, Alain Corinus, Thierry Coppola, Gabriella Gobbi, Jean-Louis Nahon, Catherine Heurteaux, Marc Borsott. Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS biology. vol 8. issue 4. 2010-09-01. PMID:20405001. spadin also induced in vivo an increase of the 5-ht neuron firing rate in the dorsal raphe nucleus. 2010-09-01 2023-08-12 mouse
Latasha K Crawford, Caryne P Craige, Sheryl G Bec. Increased intrinsic excitability of lateral wing serotonin neurons of the dorsal raphe: a mechanism for selective activation in stress circuits. Journal of neurophysiology. vol 103. issue 5. 2010-08-25. PMID:20237311. increased intrinsic excitability of lateral wing serotonin neurons of the dorsal raphe: a mechanism for selective activation in stress circuits. 2010-08-25 2023-08-12 mouse
Latasha K Crawford, Caryne P Craige, Sheryl G Bec. Increased intrinsic excitability of lateral wing serotonin neurons of the dorsal raphe: a mechanism for selective activation in stress circuits. Journal of neurophysiology. vol 103. issue 5. 2010-08-25. PMID:20237311. the primary center of serotonin (5-ht) projections to the forebrain is the dorsal raphe nucleus (dr), a region known for its role in the limbic stress response. 2010-08-25 2023-08-12 mouse
Francesco Cresp. SK channel blocker apamin attenuates the effect of SSRI fluoxetine upon cell firing in dorsal raphe nucleus: a concomitant electrophysiological and electrochemical in vivo study reveals implications for modulating extracellular 5-HT. Brain research. vol 1334. 2010-08-12. PMID:20353762. sk channel blocker apamin attenuates the effect of ssri fluoxetine upon cell firing in dorsal raphe nucleus: a concomitant electrophysiological and electrochemical in vivo study reveals implications for modulating extracellular 5-ht. 2010-08-12 2023-08-12 Not clear
Xavier López-Gil, Francesc Artigas, Albert Adel. Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex. Current pharmaceutical design. vol 16. issue 5. 2010-06-25. PMID:19909228. atypical antipsychotic drugs might further act upon 5-ht(2a), 5-ht(1a) and alpha(1)-adrenoceptors present in pyramidal cells (including those projecting to the dorsal raphe nucleus), which would directly inhibit an excessive excitability of these cells. 2010-06-25 2023-08-12 rat
G S Kranz, S Kasper, R Lanzenberge. Reward and the serotonergic system. Neuroscience. vol 166. issue 4. 2010-06-17. PMID:20109531. primate research using single-unit recording of neurons within the dorsal raphe nucleus argues for a serotonergic mediation of reward value, whereas studies using intracranial self-stimulation point to an important contribution of serotonin in modulating motivational aspects of rewarding brain stimulation. 2010-06-17 2023-08-12 human