| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Cooper, M S Grober, C R Nicholas, K L Huhma. Aggressive encounters alter the activation of serotonergic neurons and the expression of 5-HT1A mRNA in the hamster dorsal raphe nucleus. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19362123. |
serotonergic (5-ht) neurons in the dorsal raphe nucleus (drn) have been implicated in stress-induced changes in behavior. |
2009-08-24 |
2023-08-12 |
Not clear |
| Jonathan Savitz, Irwin Lucki, Wayne C Drevet. 5-HT(1A) receptor function in major depressive disorder. Progress in neurobiology. vol 88. issue 1. 2009-08-18. PMID:19428959. |
reduced somatodendritic and postsynaptic 5-ht(1a) receptor numbers or affinity have been reported in some post-mortem studies of suicide victims, a result consistent with well-replicated pet analyses demonstrating reduced 5-ht(1a) receptor binding potential in diverse regions such as the dorsal raphe, medial prefrontal cortex (mpfc), amygdala and hippocampus. |
2009-08-18 |
2023-08-12 |
mouse |
| Paul V Strong, Benjamin N Greenwood, Monika Fleshne. The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats. Psychopharmacology. vol 203. issue 4. 2009-08-17. PMID:19037632. |
learned helplessness is thought to be caused by hyperactivation of serotonin (5-ht) neurons in the dorsal raphe nucleus (drn) and a subsequent exaggerated release of 5-ht in drn projection sites. |
2009-08-17 |
2023-08-12 |
human |
| Michael J Watt, Andrew R Burke, Kenneth J Renner, Gina L Forste. Adolescent male rats exposed to social defeat exhibit altered anxiety behavior and limbic monoamines as adults. Behavioral neuroscience. vol 123. issue 3. 2009-08-13. PMID:19485563. |
adolescent defeat also affected adult monoamine levels in stress-responsive limbic regions, causing decreased medial prefrontal cortex dopamine, increased norepinephrine and serotonin in the ventral dentate gyrus, and decreased norepinephrine in the dorsal raphe. |
2009-08-13 |
2023-08-12 |
rat |
| Hideki Miura, Tetsuya Shirokawa, Kenichi Isobe, Norio Ozak. Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice. Stress (Amsterdam, Netherlands). vol 12. issue 3. 2009-08-03. PMID:19006008. |
we measured the trp, kyn, and 5-ht levels in the prefrontal cortex, hippocampus, amygdala, and dorsal raphe nuclei. |
2009-08-03 |
2023-08-12 |
mouse |
| L Dahan, H Husum, O Mnie-Filali, J Arnt, P Hertel, N Haddjer. Effects of bifeprunox and aripiprazole on rat serotonin and dopamine neuronal activity and anxiolytic behaviour. Journal of psychopharmacology (Oxford, England). vol 23. issue 2. 2009-07-28. PMID:18515444. |
using in-vivo electrophysiological and behavioural paradigms in the rat, the effects of bifeprunox and aripiprazole were assessed on ventral tegmental area (vta) dopamine and dorsal raphe serotonin (5-ht) cell activity and on foot shock-induced ultrasonic vocalisation (usv). |
2009-07-28 |
2023-08-12 |
rat |
| Cristiano Nazzaro, Silvia Marino, Mario Barbieri, Anna Siniscalch. Inhibition of serotonin outflow by nociceptin/orphaninFQ in dorsal raphe nucleus slices from normal and stressed rats: Role of corticotropin releasing factor. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19418633. |
inhibition of serotonin outflow by nociceptin/orphaninfq in dorsal raphe nucleus slices from normal and stressed rats: role of corticotropin releasing factor. |
2009-07-28 |
2023-08-12 |
rat |
| Cristiano Nazzaro, Silvia Marino, Mario Barbieri, Anna Siniscalch. Inhibition of serotonin outflow by nociceptin/orphaninFQ in dorsal raphe nucleus slices from normal and stressed rats: Role of corticotropin releasing factor. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19418633. |
dorsal raphe nucleus slices prepared from rats exposed to 15 min of forced swim stress displayed a reduced [(3)h]5-hydroxytryptamine outflow, in part reversed by antalarmin and further inhibited by nociceptin/orphaninfq. |
2009-07-28 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Ouissame Mnie-Filali, Véronique Ravailhe, Christelle Benas, Marc Marien, Cécile Bétry, Luc Zimmer, Nasser Haddjeri, Adrian Newman-Tancred. F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: influence on neuronal firing and neurotransmitter release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19326477. |
herein, we compared its effects on rat ventral tegmental area dopamine and dorsal raphe serotonin electrical activity with those of the dopamine d2 receptor partial agonist/5-ht1a receptor agonist, ssr181507. |
2009-07-07 |
2023-08-12 |
rat |
| Fabricia Viana Fonseca, André Souza Mecawi, Iracema Gomes Araujo, Gislaine Almeida-Pereira, Ana Paula Magalhães-Nunes, Daniel Badauê-Passos, Luís Carlos Rei. Role of the 5-HT(1A) somatodendritic autoreceptor in the dorsal raphe nucleus on salt satiety signaling in rats. Experimental neurology. vol 217. issue 2. 2009-07-07. PMID:19328786. |
role of the 5-ht(1a) somatodendritic autoreceptor in the dorsal raphe nucleus on salt satiety signaling in rats. |
2009-07-07 |
2023-08-12 |
rat |
| Fabricia Viana Fonseca, André Souza Mecawi, Iracema Gomes Araujo, Gislaine Almeida-Pereira, Ana Paula Magalhães-Nunes, Daniel Badauê-Passos, Luís Carlos Rei. Role of the 5-HT(1A) somatodendritic autoreceptor in the dorsal raphe nucleus on salt satiety signaling in rats. Experimental neurology. vol 217. issue 2. 2009-07-07. PMID:19328786. |
we investigated the possible role of 5-ht(1a) somatodendritic autoreceptors in the dorsal raphe nucleus (drn) on salt intake response during basal conditions and following natriorexigenic challenge aroused by sodium depletion in rats. |
2009-07-07 |
2023-08-12 |
rat |
| J Amat, E Paul, L R Watkins, S F Maie. Activation of the ventral medial prefrontal cortex during an uncontrollable stressor reproduces both the immediate and long-term protective effects of behavioral control. Neuroscience. vol 154. issue 4. 2009-06-29. PMID:18515010. |
failure to learn, exaggerated fear, dorsal raphe nucleus (drn) 5-ht activation). |
2009-06-29 |
2023-08-12 |
human |
| João M Braz, Lynn W Enquist, Allan I Basbau. Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing. The Journal of comparative neurology. vol 514. issue 2. 2009-06-25. PMID:19274668. |
we show that diverse brainstem regions differentially target the 5ht neurons of the dorsal raphe (dr) and the nucleus raphe magnus of the rostroventral medulla (rvm). |
2009-06-25 |
2023-08-12 |
mouse |
| J A Henderson, C L Bethe. Differential effects of ovarian steroids and raloxifene on serotonin 1A and 2C receptor protein expression in macaques. Endocrine. vol 33. issue 3. 2009-06-19. PMID:19021000. |
to further understand the role of ovarian hormones in the function of the serotonin neural system, we investigated the effects of estradiol (e), progesterone (p), and raloxifene on 5ht 1a and 2c receptor protein expression in the dorsal raphe region using western blot analysis. |
2009-06-19 |
2023-08-12 |
monkey |
| Ester Aso, Thibault Renoir, Guadalupe Mengod, Catherine Ledent, Michel Hamon, Rafael Maldonado, Laurence Lanfumey, Olga Valverd. Lack of CB1 receptor activity impairs serotonergic negative feedback. Journal of neurochemistry. vol 109. issue 3. 2009-06-09. PMID:19302195. |
extracellular recordings in the dorsal raphe nucleus (drn) revealed that the genetic and pharmacological blockade of cb(1) receptor induced a 5-ht(1a) autoreceptor functional desensitization. |
2009-06-09 |
2023-08-12 |
mouse |
| K G Common. Alpha4 containing nicotinic receptors are positioned to mediate postsynaptic effects on 5-HT neurons in the rat dorsal raphe nucleus. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18403129. |
alpha4 containing nicotinic receptors are positioned to mediate postsynaptic effects on 5-ht neurons in the rat dorsal raphe nucleus. |
2009-06-08 |
2023-08-12 |
rat |
| K G Common. Alpha4 containing nicotinic receptors are positioned to mediate postsynaptic effects on 5-HT neurons in the rat dorsal raphe nucleus. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18403129. |
therefore in this study it was examined how alpha4-containing receptors are positioned to modulate the function of 5-ht neurons using ultrastructural analysis of immunolabeling for the alpha4 receptor subunit in the dorsal raphe nucleus (dr), a primary source of forebrain 5-ht in the rat. |
2009-06-08 |
2023-08-12 |
rat |
| E Martínez-García, B García-Iglesias, J A Terró. Effect of central serotonin depletion on 5-HT receptor-mediated vasomotor responses in the middle meningeal artery of anaesthetized rats. Autonomic & autacoid pharmacology. vol 29. issue 1-2. 2009-06-08. PMID:19302555. |
2 pretreatment with 5,7-dht produced a drastic and selective decrease of 5-ht levels in the brain (78 +/- 6% and 94 +/- 2% in dorsal raphe and hypothalamic paraventricular nuclei, respectively) compared with controls (1% ascorbic acid). |
2009-06-08 |
2023-08-12 |
rat |
| Laura Lambás-Señas, Ouissame Mnie-Filali, Véronique Certin, Céline Faure, Laetitia Lemoine, Luc Zimmer, Nasser Haddjer. Functional correlates for 5-HT(1A) receptors in maternally deprived rats displaying anxiety and depression-like behaviors. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19111592. |
although the hypothermic response to the 5-ht(1a) receptor agonist 8-oh-dpat was increased in adult deprived rats compared to non-deprived control group, no differences between groups were found in the effect of the systemic 8-oh-dpat administration on serotoninergic cell firing in dorsal raphe nucleus and in the 5-ht release at the ventral hippocampus levels. |
2009-06-02 |
2023-08-12 |
rat |
| Renato Leonardo Freitas, Célio Marcos dos Reis Ferreira, Maria Angélica Castiblanco Urbina, Andrés Uribe Mariño, Andressa Daiane Carvalho, Giuseppe Butera, Ana Maria de Oliveira, Norberto Cysne Coimbr. 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. Experimental neurology. vol 217. issue 1. 2009-05-26. PMID:19416688. |
however, when the same 5-hydroxytryptamine receptors antagonist was microinjected (at 1.0, 3.0 and 5.0 microg/0.2 microl) in the dorsal raphe nucleus, a mesencephalic structure rich in serotonergic neurons and 5-ht receptors, the post-ictal hypo-analgesia was consistently antagonized. |
2009-05-26 |
2023-08-12 |
Not clear |