| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanlin He, Xing Cai, Hailan Liu, Krisitine M Conde, Pingwen Xu, Yongxiang Li, Chunmei Wang, Meng Yu, Yang He, Hesong Liu, Chen Liang, Tingting Yang, Yongjie Yang, Kaifan Yu, Julia Wang, Rong Zheng, Feng Liu, Zheng Sun, Lora Heisler, Qi Wu, Qingchun Tong, Canjun Zhu, Gang Shu, Yong X. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Molecular psychiatry. 2021-08-04. PMID:34290371. |
5-hydroxytryptamine (5-ht) neurons in the dorsal raphe nucleus (5-ht |
2021-08-04 |
2023-08-13 |
Not clear |
| Zhixiang Liu, Rui Lin, Minmin Lu. Reward Contributions to Serotonergic Functions. Annual review of neuroscience. vol 43. 2021-08-02. PMID:32640931. |
here, we review recent progress on the organization and physiology of the dorsal raphe serotonin neurons and the relationships between their activity and behavioral functions in the context of reward processing. |
2021-08-02 |
2023-08-13 |
Not clear |
| Margherita Tassan Mazzocco, Fabrizia Claudia Guarnieri, Elena Monzani, Fabio Benfenati, Flavia Valtorta, Stefano Coma. Dysfunction of the serotonergic system in the brain of synapsin triple knockout mice is associated with behavioral abnormalities resembling synapsin-related human pathologies. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:33058959. |
using in vivo electrophysiology, we recorded the spontaneous activity of dorsal raphe nucleus (drn) serotonin (5-ht) and ventral tegmental area (vta) dopamine (da) neurons. |
2021-07-19 |
2023-08-13 |
mouse |
| Saida Oubraim, Ruixiang Wang, Kathryn A Hausknecht, Roh-Yu Shen, Samir Haj-Dahman. Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors. Frontiers in pharmacology. vol 12. 2021-07-16. PMID:34262460. |
tonic endocannabinoid signaling gates synaptic plasticity in dorsal raphe nucleus serotonin neurons through peroxisome proliferator-activated receptors. |
2021-07-16 |
2023-08-13 |
Not clear |
| Saida Oubraim, Ruixiang Wang, Kathryn A Hausknecht, Roh-Yu Shen, Samir Haj-Dahman. Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors. Frontiers in pharmacology. vol 12. 2021-07-16. PMID:34262460. |
in this study, we show that both 2-ag and aea are constitutively released in the dorsal raphe nucleus (drn), where they exert tonic control of glutamatergic synaptic transmission onto serotonin (5-ht) neurons. |
2021-07-16 |
2023-08-13 |
Not clear |
| Yong Han, Guobin Xia, Dollada Srisai, Fantao Meng, Yanlin He, Yali Ran, Yang He, Monica Farias, Giang Hoang, István Tóth, Marcelo O Dietrich, Miao-Hsueh Chen, Yong Xu, Qi W. Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nature communications. vol 12. issue 1. 2021-06-29. PMID:34112797. |
here, we report that energy expenditure is regulated by a subgroup of agrp neurons that send non-collateral projections to neurons within the dorsal lateral part of dorsal raphe nucleus (dldrn) expressing the melanocortin 4 receptor (mc4r), which in turn innervate nearby serotonergic (5-ht) neurons. |
2021-06-29 |
2023-08-13 |
Not clear |
| Melina Matthiesen, Leonardo D Mendes, Ailton Spiacci, Eduardo At Fortaleza, Fernando Ma Corrêa, Hélio Zangross. Serotonin 2C receptors in the basolateral amygdala mediate the anxiogenic effect caused by serotonergic activation of the dorsal raphe dorsomedial subnucleus. Journal of psychopharmacology (Oxford, England). vol 34. issue 4. 2021-06-25. PMID:31637976. |
serotonin 2c receptors in the basolateral amygdala mediate the anxiogenic effect caused by serotonergic activation of the dorsal raphe dorsomedial subnucleus. |
2021-06-25 |
2023-08-13 |
Not clear |
| Sheng-Rong Zhang, Jian-Lin Wu, Hao Chen, Rong Luo, Wen-Jun Chen, Li-Juan Tang, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Ga. ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:31905370. |
here, using transgenic and viral approaches, we show that mice with erbb4 deficiency in 5-ht neurons exhibit heightened anxiety-like behavior and impaired fear extinction, possibly due to an increased excitability of 5-ht neurons in the dorsal raphe nucleus (drn). |
2021-06-23 |
2023-08-13 |
mouse |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
deep brain stimulation of the dorsal raphe abolishes serotonin 1a facilitation of ampa receptor-mediated synaptic currents in the ventral hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Kathryn G Common. Dorsal raphe organization. Journal of chemical neuroanatomy. vol 110. 2021-06-16. PMID:33031916. |
a recent cluster of reports have considerably deepened our understanding of the transcriptional diversity of serotonin neurons of the dorsal raphe nucleus (dr). |
2021-06-16 |
2023-08-13 |
Not clear |
| Luisa Lo Iacono, Donald Ielpo, Chiara Parisi, Giulia Napoli, Alessandra Accoto, Matteo Di Segni, Lucy Babicola, Sebastian Luca D'Addario, Serafina Manila Guzzo, Tiziana Pascucci, Rossella Ventura, Diego Andolin. MicroRNA-34a regulates 5-HT2C expression in dorsal raphe and contributes to the anti-depressant-like effect of fluoxetine. Neuropharmacology. vol 190. 2021-06-09. PMID:33845072. |
moreover, using a pharmacological strategy, we found that an increased expression of the serotonin 2c (5-ht2c) receptor in the dorsal raphe region of the brain contributes to this phenotype. |
2021-06-09 |
2023-08-13 |
mouse |
| Fabiana C Vilela, Jádina S Vieira, Fernando Vitor-Vieira, Bruna Kalil-Cutti, Josie R T da Silva, Alexandre Giusti-Paiva, Marcelo L da Silv. Maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. Neuroscience letters. vol 748. 2021-06-03. PMID:33596470. |
this study consisted of two experiments: 1) to confirm whether maternal separation increased pain sensitivity (n = 8 per group) and to evaluate the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus in animals subjected to maternal separation in comparison to controls (n = 6 per group); and 2) to evaluate the effect of fluoxetine (a selective 5-ht reuptake inhibitor) and desipramine (a na reuptake inhibitor) on sensitivity to chemical stimulation using formalin in animals subjected to maternal separation (n = 8 per group). |
2021-06-03 |
2023-08-13 |
rat |
| David K Oliver, Katheron Intson, Derya Sargin, Saige K Power, Janice McNabb, Amy J Ramsey, Evelyn K Lamb. Chronic social isolation exerts opposing sex-specific consequences on serotonin neuronal excitability and behaviour. Neuropharmacology. vol 168. 2021-05-27. PMID:32092443. |
therefore, we investigated this question in mice of both sexes, asking how the long-term stress of social isolation (from weaning into adulthood) affects the excitability of serotonin neurons in the dorsal raphe nucleus as well as mouse behaviour. |
2021-05-27 |
2023-08-13 |
mouse |
| Andrea Forero, Hsing-Ping Ku, Ana Belén Malpartida, Sina Wäldchen, Judit Alhama-Riba, Christina Kulka, Benjamin Aboagye, William H J Norton, Andrew M J Young, Yu-Qiang Ding, Robert Blum, Markus Sauer, Olga Rivero, Klaus-Peter Lesc. Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. vol 168. 2021-05-27. PMID:32113967. |
our results show that exclusive inactivation of cdh13 in 5-ht neurons selectively increases 5-ht neuron density in the embryonic dorsal raphe, with persistence into adulthood, and serotonergic innervation of the developing prefrontal cortex. |
2021-05-27 |
2023-08-13 |
mouse |
| Andrea Forero, Hsing-Ping Ku, Ana Belén Malpartida, Sina Wäldchen, Judit Alhama-Riba, Christina Kulka, Benjamin Aboagye, William H J Norton, Andrew M J Young, Yu-Qiang Ding, Robert Blum, Markus Sauer, Olga Rivero, Klaus-Peter Lesc. Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. vol 168. 2021-05-27. PMID:32113967. |
our findings further support the critical role of cdh13 in the development of dorsal raphe 5-ht circuitries, a mechanism that may underlie specific clinical features observed in neurodevelopmental disorders. |
2021-05-27 |
2023-08-13 |
mouse |
| Xiaotao Li, Shanping Chen, Haiyang Yang, Xiang Li, Kwok-Fai So, Liping Wan. GABAergic Neurons in the Dorsal Raphe Nucleus that Express 5-HT3A Receptors Participate in Responses to Stress Hormones. Neuroscience. vol 441. 2021-05-14. PMID:32512137. |
the dorsal raphe nucleus (drn) participates in stress responses and in mood regulation via its ascending release of serotonin (5-ht) onto neural circuits within the forebrain. |
2021-05-14 |
2023-08-13 |
rat |
| Hailan Liu, Chunmei Wang, Meng Yu, Yongjie Yang, Yang He, Hesong Liu, Chen Liang, Longlong Tu, Nan Zhang, Lina Wang, Julia Wang, Feng Liu, Fang Hu, Yong X. TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner. Endocrinology. vol 162. issue 1. 2021-05-14. PMID:33034617. |
abstractcentral 5-hydroxytryptamine (5-ht), which is primarily synthesized by tryptophan hydroxylase 2 (tph2) in the dorsal raphe nuclei (drn), plays a pivotal role in the regulation of food intake and body weight. |
2021-05-14 |
2023-08-13 |
mouse |
| B Coutens, K Rekik, A Harster, P Etienne, V Noirot, B Frances, L Moulédous, B P Guiar. A Citrus Based Sensory Functional Food Ingredient Induces Antidepressant-like Effects: Possible Involvement of an Interplay between the Olfactory and the Serotonergic Systems. Neuroscience. vol 451. 2021-05-14. PMID:33039523. |
serotonin and norepinephrine), it reversed the ability of cort to decrease serotonin neurons firing rate in the dorsal raphe and neuronal maturation in the hippocampus. |
2021-05-14 |
2023-08-13 |
mouse |
| Alexandra N Petrucci, Katelyn G Joyal, Jonathan W Chou, Rui Li, Kimberly M Vencer, Gordon F Buchana. Post-ictal Generalized EEG Suppression is reduced by Enhancing Dorsal Raphe Serotonergic Neurotransmission. Neuroscience. vol 453. 2021-05-14. PMID:33242541. |
seizures suppress activity of 5-ht neurons in the dorsal raphe nucleus (drn). |
2021-05-14 |
2023-08-13 |
mouse |
| Hugo R Arias, Katarzyna M Targowska-Duda, Jesús García-Colunga, Marcelo O Ortell. Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors? Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-13. PMID:33917953. |
studies on dorsal raphe nucleus serotoninergic neurons support the concept that ssri-induced nachr inhibition decreases the glutamatergic hyperstimulation observed in stress conditions, which compensates the excessive 5-ht overflow in these neurons and, consequently, ameliorates depression symptoms. |
2021-05-13 |
2023-08-13 |
Not clear |