All Relations between hippocampus and Autism Spectrum Disorder

Publication Sentence Publish Date Extraction Date Species
Tegan A White, Suzanne L Miller, Amy E Sutherland, Beth J Allison, Emily J Cam. Perinatal compromise affects development, form, and function of the hippocampus part one; clinical studies. Pediatric research. 2024-03-23. PMID:38519794. in turn, deficits in hippocampal development and structure mediate a range of neurodevelopmental disorders, including cognitive and learning problems, autism, and attention-deficit/hyperactivity disorder (adhd). 2024-03-23 2024-03-26 human
Isabel Barón-Mendoza, Montserrat Mejía-Hernández, Karina Hernández-Mercado, Jessica Guzmán-Condado, Angélica Zepeda, Aliesha González-Arena. Altered hippocampal neurogenesis in a mouse model of autism revealed by genetic polymorphisms and by atypical development of newborn neurons. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38409172. altered hippocampal neurogenesis in a mouse model of autism revealed by genetic polymorphisms and by atypical development of newborn neurons. 2024-02-28 2024-03-01 mouse
Isabel Barón-Mendoza, Montserrat Mejía-Hernández, Karina Hernández-Mercado, Jessica Guzmán-Condado, Angélica Zepeda, Aliesha González-Arena. Altered hippocampal neurogenesis in a mouse model of autism revealed by genetic polymorphisms and by atypical development of newborn neurons. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38409172. individuals with autism spectrum disorder (asd) often exhibit atypical hippocampal anatomy and connectivity throughout their lifespan, potentially linked to alterations in the neurogenic process within the hippocampus. 2024-02-28 2024-03-01 mouse
Lindsay E Rexrode, Joshua Hartley, Kurt C Showmaker, Lavanya Challagundla, Michael W Vandewege, Brigitte E Martin, Estelle Blair, Ratna Bollavarapu, Rhenius B Antonyraj, Keauna Hilton, Alex Gardiner, Jake Valeri, Barbara Gisabella, Michael R Garrett, Theoharis C Theoharides, Harry Pantazopoulo. Molecular profiling of the hippocampus of children with autism spectrum disorder. Molecular psychiatry. 2024-02-14. PMID:38355786. molecular profiling of the hippocampus of children with autism spectrum disorder. 2024-02-14 2024-02-17 mouse
Khadijeh Mirzaee Khoram-Abadi, Sara Haratizadeh, Mohsen Basiri, Mahdieh Parvan, Fahimeh Pourjafari, Iraj Aghaei, Sedigheh Amiresmaili, Masoumeh Nozar. Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus. Iranian journal of basic medical sciences. vol 27. issue 3. 2024-02-09. PMID:38333751. due to the crucial role of polyamines during fetal growth and development, we aimed to determine the effect of prenatal administration of agmatine, an endogenous active metabolite of arginine, and a nutritional supplement, on autistic-like behaviors, oxidative-anti-oxidative profile, and histopathological changes of the prefrontal cortex (pfc) and ca1 area of the hippocampus in valproic acid (vpa) model of autism in male rats. 2024-02-09 2024-02-11 rat
Leandra Severino, Jinhyun Kim, Min-Ho Nam, Thomas J McHug. From synapses to circuits: What mouse models have taught us about how autism spectrum disorder impacts hippocampal function. Neuroscience and biobehavioral reviews. 2024-01-21. PMID:38246230. from synapses to circuits: what mouse models have taught us about how autism spectrum disorder impacts hippocampal function. 2024-01-21 2024-01-24 mouse
Yanan Deng, Liping Ma, Ziwei Du, Huixin Ma, Yuxi Xia, Liran Ping, Zhaoxing Chen, Yinghua Zhan. The Notch1/Hes1 pathway regulates Neuregulin 1/ErbB4 and participates in microglial activation in rats with VPA-induced autism. Progress in neuro-psychopharmacology & biological psychiatry. 2024-01-19. PMID:38242426. our results suggest that the levels of notch1, hes1, nrg1, and phosphorylated erbb4 in the cerebellum (cb), hippocampus (hc), and prefrontal cortex (pfc) were increased in rats with valproic acid (vpa)-induced autism compared to those in the con group. 2024-01-19 2024-01-22 rat
Sébastien Delhaye, Marielle Jarjat, Asma Boulksibat, Clara Sanchez, Alessandra Tempio, Andrei Turtoi, Mauro Giorgi, Sandra Lacas-Gervais, Gabriele Baj, Carole Rovere, Viviana Trezza, Manuela Pellegrini, Thomas Maurin, Enzo Lalli, Barbara Bardon. Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of phosphodiesterase 2 a. Neurobiology of disease. 2023-12-28. PMID:38154608. in cerebral cortex and hippocampus, pde2a expression level is upregulated in fmr1-ko mice, a model of the fragile x syndrome (fxs), the most common form of inherited intellectual disability (id) and autism spectrum disorder (asd). 2023-12-28 2023-12-31 mouse
Juan F Duarte-Campos, C Noé Vázquez-Moreno, Mónica Martínez-Marcial, Anahí Chavarría, Ricardo Jair Ramírez-Carreto, Marco A Velasco Velázquez, Marisol De La Fuente-Granada, Aliesha González-Arena. Changes in neuroinflammatory markers and microglial density in the hippocampus and prefrontal cortex of the C58/J mouse model of autism. The European journal of neuroscience. 2023-12-07. PMID:38057955. changes in neuroinflammatory markers and microglial density in the hippocampus and prefrontal cortex of the c58/j mouse model of autism. 2023-12-07 2023-12-10 mouse
Lauretta El Hayek, Darlene DeVries, Ashlesha Gogate, Ariel Aiken, Kiran Kaur, Maria H Chahrou. Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity. Science advances. vol 9. issue 47. 2023-11-24. PMID:37992166. disruption of the autism gene and chromatin regulator kdm5a alters hippocampal cell identity. 2023-11-24 2023-11-28 Not clear
Gonzalo Ugarte, Ricardo Piña, Darwin Contreras, Felipe Godoy, David Rubio, Carlos Rozas, Marc Zeise, Rodrigo Vidal, Jorge Escobar, Bernardo Morale. Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity. Biology. vol 12. issue 9. 2023-09-28. PMID:37759640. magnetic resonance imaging (mri) has revealed that neuroanatomical abnormalities such as the volume reduction in the neocortex and hippocampus are shared by several neuropsychiatric diseases such as schizophrenia, autism spectrum disorder and adhd. 2023-09-28 2023-10-07 Not clear
Yue Ming, Zhihui Deng, Xianhua Tian, Yuerong Jia, Meng Ning, Shuhua Chen. Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism. Metabolic brain disease. 2023-09-26. PMID:37751122. anti-apoptotic capacity of malat1 on hippocampal neurons correlates with casp3 dna methylation in a mouse model of autism. 2023-09-26 2023-10-07 mouse
Yue Ming, Zhihui Deng, Xianhua Tian, Yuerong Jia, Meng Ning, Shuhua Chen. Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism. Metabolic brain disease. 2023-09-26. PMID:37751122. this study primarily investigates the underlying mechanism of how the long non-coding rna malat1 affects neuronal apoptosis in the hippocampus of mice with autism spectrum disorder (asd). 2023-09-26 2023-10-07 mouse
Carolina D Alberca, Ligia A Papale, Andy Madrid, Reid S Alisc. Hippocampal and peripheral blood DNA methylation signatures correlate at the gene and pathway level in a mouse model of autism. Human molecular genetics. 2023-09-02. PMID:37658766. hippocampal and peripheral blood dna methylation signatures correlate at the gene and pathway level in a mouse model of autism. 2023-09-02 2023-09-07 mouse
Maryam Saadat, Abbas Ali Taherian, Mohammad Reza Aldaghi, Payman Raise-Abdullahi, Hamid Reza Sameni, Abbas Ali Vafae. Prangos ferulacea (L.) ameliorates behavioral alterations, hippocampal oxidative stress markers, and apoptotic deficits in a rat model of autism induced by valproic acid. Brain and behavior. 2023-08-18. PMID:37596045. prangos ferulacea (l.) ameliorates behavioral alterations, hippocampal oxidative stress markers, and apoptotic deficits in a rat model of autism induced by valproic acid. 2023-08-18 2023-10-07 rat
Maryam Saadat, Abbas Ali Taherian, Mohammad Reza Aldaghi, Payman Raise-Abdullahi, Hamid Reza Sameni, Abbas Ali Vafae. Prangos ferulacea (L.) ameliorates behavioral alterations, hippocampal oxidative stress markers, and apoptotic deficits in a rat model of autism induced by valproic acid. Brain and behavior. 2023-08-18. PMID:37596045. this study investigated the effect of prangos ferulacea (l.) on behavioral alterations, hippocampal oxidative stress markers, and apoptotic deficits in a rat model of autism induced by valproic acid. 2023-08-18 2023-10-07 rat
Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Chen. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model. Molecular neurobiology. 2023-08-17. PMID:37592184. as the hippocampus and prefrontal cortex are involved in social recognition, they are the regions of the brain implicated in autism. 2023-08-17 2023-09-07 rat
Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Chen. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model. Molecular neurobiology. 2023-08-17. PMID:37592184. mrna and mirna sequencing was performed on samples from the hippocampus and prefrontal cortex of the vpa model of autism. 2023-08-17 2023-09-07 rat
Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Chen. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model. Molecular neurobiology. 2023-08-17. PMID:37592184. importantly, the fact that mir-10a-5p downregulated grm3 in both the hippocampus and the prefrontal cortex may play a potentially significant role in the occurrence and development of autism. 2023-08-17 2023-09-07 rat
Janina Neufeld, Simon Maier, Mirian Revers, Marco Reisert, Ralf Kuja-Halkola, Ludger Tebartz van Elst, Sven Bölt. Reduced brain connectivity along the autism spectrum controlled for familial confounding by co-twin design. Scientific reports. vol 13. issue 1. 2023-08-12. PMID:37573391. reduced brainstem-cuneus connectivity might point towards alterations in low-level visual processing in clinical autism while higher autistic traits seemed to be more associated with reduced connectivity in networks involving the hippocampus and the fusiform gyrus, crucial especially for processing of faces and other (higher order) visual processing. 2023-08-12 2023-08-16 Not clear