| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T C Ma, X Z Zh. Neurotoxic effects of interleukin-6 and sodium nitroprusside on cultured rat hippocampal neurons. Arzneimittel-Forschung. vol 50. issue 6. 2000-09-12. PMID:10918941. |
these results indicate that il-6 exerts neurotoxicity on cultured hippocampal neurons probably via overformation of nitric oxide in cultures. |
2000-09-12 |
2023-08-12 |
rat |
| L Kanit, D Taskiran, O A Yilmaz, B Balkan, S Demirgören, J J Furedy, S Pögü. Sexually dimorphic cognitive style in rats emerges after puberty. Brain research bulletin. vol 52. issue 4. 2000-08-09. PMID:10856821. |
since nitric oxide (no) is implicated in spatial learning and hippocampal function, and since brain no(-)(2) + no(-)(3) levels (stable metabolites of no) display region-specific sex differences in rat brain, no(-)(2) + no(-)(3) levels were determined after behavioral testing. |
2000-08-09 |
2023-08-12 |
human |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. |
2000-08-01 |
2023-08-12 |
rat |
| S Bastianetto, W H Zheng, R Quirio. The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C. Journal of neurochemistry. vol 74. issue 6. 2000-06-02. PMID:10820186. |
the ginkgo biloba extract (egb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase c. an excess of the free radical nitric oxide (no) is viewed as a deleterious factor involved in various cns disorders. |
2000-06-02 |
2023-08-12 |
rat |
| M Qiang, J Xie, H Wang, J Qia. Effect of nitric oxide synthesis inhibition on c-Fos expression in hippocampus and cerebral cortex following two forms of learning in rats: an immunohistochemistry study. Behavioural pharmacology. vol 10. issue 2. 2000-05-18. PMID:10780834. |
effect of nitric oxide synthesis inhibition on c-fos expression in hippocampus and cerebral cortex following two forms of learning in rats: an immunohistochemistry study. |
2000-05-18 |
2023-08-12 |
rat |
| T C Ma, X Z Zh. Effects of intrahippocampal infusion of interleukin-6 on passive avoidance and nitrite and prostaglandin levels in the hippocampus in rats. Arzneimittel-Forschung. vol 50. issue 3. 2000-05-09. PMID:10758772. |
these results indicate that il-6 impairs retention of passive avoidance probably via the overproduction of nitric oxide (no) and suggest that il-6 may possess an inducible effect on no synthase and cyclo-oxygenase in the hippocampus. |
2000-05-09 |
2023-08-12 |
rat |
| K Maiese, A M Vincen. Membrane asymmetry and DNA degradation: functionally distinct determinants of neuronal programmed cell death. Journal of neuroscience research. vol 59. issue 4. 2000-04-28. PMID:10679797. |
employing both a novel assay to follow serially pcd in individual living neurons and the neuroprotective agent lubeluzole as an investigative tool, we examined the development of nitric oxide (no)-induced pcd over time through the reversible annexin v labelling of membrane phosphatidylserine (ps) exposure and the electron microscopy of genomic dna in primary rat hippocampal neurons. |
2000-04-28 |
2023-08-12 |
rat |
| J Wu, T Kikuchi, Y Wang, K Sato, F Okumur. NOx- concentrations in the rat hippocampus and striatum have no direct relationship to anaesthesia induced by ketamine. British journal of anaesthesia. vol 84. issue 2. 2000-04-12. PMID:10743451. |
using microdialysis, we have examined the effects of ketamine on concentrations of total nitric oxide oxidation products (nox-) in the rat hippocampus and striatum in vivo to investigate the relationship between anaesthesia and nox- production in the brain. |
2000-04-12 |
2023-08-12 |
rat |
| W M Lue, M T Su, W B Lin, P L Ta. The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices. European journal of pharmacology. vol 383. issue 2. 2000-02-03. PMID:10585526. |
the role of nitric oxide in the development of morphine tolerance in rat hippocampal slices. |
2000-02-03 |
2023-08-12 |
rat |
| W M Lue, M T Su, W B Lin, P L Ta. The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices. European journal of pharmacology. vol 383. issue 2. 2000-02-03. PMID:10585526. |
in the present study, we investigated the effects of a nitric oxide (no) precursor, l-arginine, on the effect of different drugs, [trans-3, 4-dichloro-n-methyl-n-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamid e hydrochloride] (u-50,488, a kappa-opioid receptor agonist); dptyr(me)avp (a vasopressin receptor antagonist); dizocilpine (mk-801, a n-methyl-d-aspartate (nmda) receptor antagonist), to block the development of morphine tolerance or no release in sprague-dawley rat hippocampal slices (450 microm). |
2000-02-03 |
2023-08-12 |
rat |
| J Keelan, O Vergun, M R Duche. Excitotoxic mitochondrial depolarisation requires both calcium and nitric oxide in rat hippocampal neurons. The Journal of physiology. vol 520 Pt 3. 2000-02-01. PMID:10545145. |
excitotoxic mitochondrial depolarisation requires both calcium and nitric oxide in rat hippocampal neurons. |
2000-02-01 |
2023-08-12 |
rat |
| B Lei, N Adachi, T Nagaro, T Ara. Measurement of total nitric oxide metabolite (NO(x)(-)) levels in vivo. Brain research. Brain research protocols. vol 4. issue 3. 2000-01-24. PMID:10592352. |
neurosci., 3 (1994), 217-221; h. togashi, k. mori, k. ueno, m. matsumoto, n. suda, h. saito, m. yoshika, consecutive evaluation of nitric oxide production after transient cerebral ischemia in the rat hippocampus using in vivo brain microdialysis, neurosci. |
2000-01-24 |
2023-08-12 |
rat |
| Y F Lu, E R Kandel, R D Hawkin. Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575022. |
nitric oxide signaling contributes to late-phase ltp and creb phosphorylation in the hippocampus. |
1999-12-17 |
2023-08-12 |
mouse |
| A K Hammarström, P W Gag. Nitric oxide increases persistent sodium current in rat hippocampal neurons. The Journal of physiology. vol 520 Pt 2. 1999-12-15. PMID:10523414. |
nitric oxide increases persistent sodium current in rat hippocampal neurons. |
1999-12-15 |
2023-08-12 |
rat |
| A K Hammarström, P W Gag. Nitric oxide increases persistent sodium current in rat hippocampal neurons. The Journal of physiology. vol 520 Pt 2. 1999-12-15. PMID:10523414. |
the effects of nitric oxide (no) donors on whole-cell, ttx-sensitive sodium currents and single sodium channels in excised patches were examined in rat hippocampal neurons. |
1999-12-15 |
2023-08-12 |
rat |
| J G Liu, R Li, G Q Li. l-S.R-daurisoline protects cultured hippocampal neurons against glutamate neurotoxicity by reducing nitric oxide production. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 20. issue 1. 1999-12-09. PMID:10437119. |
l-s.r-daurisoline protects cultured hippocampal neurons against glutamate neurotoxicity by reducing nitric oxide production. |
1999-12-09 |
2023-08-12 |
Not clear |
| H Matsuzaki, M Tamatani, N Mitsuda, K Namikawa, H Kiyama, S Miyake, M Tohyam. Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537063. |
activation of akt kinase inhibits apoptosis and changes in bcl-2 and bax expression induced by nitric oxide in primary hippocampal neurons. |
1999-11-05 |
2023-08-12 |
Not clear |
| A M Vincent, M TenBroeke, K Maies. Neuronal intracellular pH directly mediates nitric oxide-induced programmed cell death. Journal of neurobiology. vol 40. issue 2. 1999-11-04. PMID:10413448. |
since these endonucleases are exquisitely ph dependent, we investigated in primary rat hippocampal neurons the role of intracellular ph (ph(i)) regulation during nitric oxide (no)-induced toxicity. |
1999-11-04 |
2023-08-12 |
rat |
| M H Jiang, T Kaku, J Hada, Y Hayash. 7-Nitroindazole reduces nitric oxide concentration in rat hippocampus after transient forebrain ischemia. European journal of pharmacology. vol 380. issue 2-3. 1999-11-01. PMID:10513570. |
7-nitroindazole reduces nitric oxide concentration in rat hippocampus after transient forebrain ischemia. |
1999-11-01 |
2023-08-12 |
rat |
| M H Jiang, T Kaku, J Hada, Y Hayash. 7-Nitroindazole reduces nitric oxide concentration in rat hippocampus after transient forebrain ischemia. European journal of pharmacology. vol 380. issue 2-3. 1999-11-01. PMID:10513570. |
we investigated the effects of 7-nitroindazole, a specific inhibitor of neuronal nitric oxide (no) synthase, on no concentration and on blood flow in rat hippocampus after transient forebrain ischemia which was induced by 4-vessel occlusion for 10 min. |
1999-11-01 |
2023-08-12 |
rat |