| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun Wang, Mixia Wang, Yuchuan Dai, Yilin Song, Yiding Wang, Botao Lu, Yinghui Li, Xinxia Ca. PtNPs/Short MWCNT-PEDOT: PSS-Modified Microelectrode Array to Detect Neuronal Firing Patterns in the Dorsal Raphe Nucleus and Hippocampus of Insomnia Rats. Micromachines. vol 13. issue 3. 2022-03-26. PMID:35334780. |
in order to explore the effect of 5-ht deficiency-induced insomnia on brain regions related to memory in rats, we designed and fabricated a microelectrode array that simultaneously detects the electrical activity of the dorsal raphe nucleus (drn) and hippocampus in normal, insomnia and recovery rats in vivo. |
2022-03-26 |
2023-08-13 |
rat |
| Yun Wang, Mixia Wang, Yuchuan Dai, Yilin Song, Yiding Wang, Botao Lu, Yinghui Li, Xinxia Ca. PtNPs/Short MWCNT-PEDOT: PSS-Modified Microelectrode Array to Detect Neuronal Firing Patterns in the Dorsal Raphe Nucleus and Hippocampus of Insomnia Rats. Micromachines. vol 13. issue 3. 2022-03-26. PMID:35334780. |
our findings suggest that 5-ht deficiency causes the hyperactivity of neurons in the hippocampus and drn; the drn's firing rate and the hippocampal neuronal amplitude reflect insomnia in rats more effectively. |
2022-03-26 |
2023-08-13 |
rat |
| Runlong Zhao, Yalin Zhou, Hanxu Shi, Wanyun Ye, Ying Lyu, Zhang Wen, Rui Li, Yajun X. Effect of Gestational Diabetes on Postpartum Depression-like Behavior in Rats and Its Mechanism. Nutrients. vol 14. issue 6. 2022-03-26. PMID:35334886. |
the hpa axis hormone did not show the typical stress state of depression, but the level of 5-ht decreased significantly in serum, prefrontal cortex and hippocampus, and the kyn/trp ratio increased significantly in serum and prefrontal cortex, implying the switch of the tryptophan (trp) metabolism from the 5-ht pathway to the kynurenine (kyn) pathway. |
2022-03-26 |
2023-08-13 |
rat |
| Britt T J van Hagen, Nick P van Goethem, Ellis Nelissen, Dean Paes, Karin Koymans, Scott van Hoof, Rudy Schreiber, Mark Varney, Adrian Newman-Tancredi, Jos Prickaert. Biased 5-HT Molecular and cellular neurosciences. 2022-03-14. PMID:35283305. |
biased 5-ht pattern separation is a hippocampal process in which highly similar stimuli are recognized as separate representations, and deficits could lead to memory impairments in neuropsychiatric disorders such as schizophrenia. |
2022-03-14 |
2023-08-13 |
Not clear |
| Princewill Ikechukwu Ugwu, Benneth Ben-Azu, Sandra Ugonne Ugwu, Christian I Uruaka, Chinecherem Choice Nworgu, Pamela Onyinye Okorie, Kizito Oluchukwu Okafor, Kenneth Kelechi Anachuna, Melford Uche Elendu, Amogechukwu Onyinye Ugwu, Ugochukwu Bond Anyaehie, Azubuike A Nwankwo, Eme Effiom Osi. Putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin. Brain research bulletin. 2022-03-12. PMID:35278662. |
the decreased serotonin in the prefrontal-cortex and dopamine in the striatum, elevated levels of noradrenaline and acetylcholinesterase in the prefrontal-cortex and hippocampus with corresponding decrease in bdnf were reversed by quercetin. |
2022-03-12 |
2023-08-13 |
mouse |
| Kateryna Murlanova, Netanela Cohen, Anna Pinkus, Liudmila Vinnikova, Mikhail Pletnikov, Michael Kirby, Jonathan Gorelick, Elyashiv Drori, Albert Pinhaso. Antidepressant-like effects of a chlorogenic acid- and cynarine-enriched fraction from Dittrichia viscosa root extract. Scientific reports. vol 12. issue 1. 2022-03-08. PMID:35256610. |
neurochemical profiling for 5-hydroxytryptamine (5-ht) and its primary metabolite, 5-hydroxyindoleacetic acid (5-hiaa), in prefrontal cortex and hippocampus of "k"-treated mice showed reduction in 5-hiaa, indicative of either serotonin uptake transporter or monoamine oxidase-a inhibition, as well as slight increases in 5-ht content. |
2022-03-08 |
2023-08-13 |
mouse |
| Hongxuan Kuang, Wenji Zhou, Yingwei Zeng, Da Xu, Wanqi Zhu, Shengjie Lin, Ruifang Fa. Dose makes poison: Insights into the neurotoxicity of perinatal and juvenile exposure to environmental doses of 16 priority-controlled PAHs. Chemosphere. 2022-03-08. PMID:35257710. |
except for serotonin, no significant difference in hippocampal and cortical neurotransmitter concentrations was observed between the control and pahs-exposed groups. |
2022-03-08 |
2023-08-13 |
mouse |
| Aanchal Aggarwal, Aarti Yadav, Neetu Saini, Rajat Sandhi. S-nitrosoglutathione alleviates hyperglycemia-induced neurobehavioral deficits involving nitro-oxidative stress and aberrant monaminergic system. Nitric oxide : biology and chemistry. 2022-03-08. PMID:35257853. |
these neurobehavioral deficits observed in diabetic mice could be attributed to decrease in norepinephrine (ne), dopamine (da), serotonin (5-ht) and increased monoamine oxidase (mao) activity in cortex and hippocampus. |
2022-03-08 |
2023-08-13 |
mouse |
| Sreyashi Samaddar, Sudarshana Purkayastha, Souleymane Diallo, Subramanyam J Tantry, Ryan Schroder, Pranavan Chanthrakumar, Michael J Flory, Probal Banerje. The G Protein-Coupled Serotonin 1A Receptor Augments Protein Kinase Cε-Mediated Neurogenesis in Neonatal Mouse Hippocampus-PKCε-Mediated Signaling in the Early Hippocampus. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216076. |
the g protein-coupled serotonin 1a receptor augments protein kinase cε-mediated neurogenesis in neonatal mouse hippocampus-pkcε-mediated signaling in the early hippocampus. |
2022-02-26 |
2023-08-13 |
mouse |
| Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Woźniak, Barbara Budzyńsk. Imperatorin Influences Depressive-like Behaviors: A Preclinical Study on Behavioral and Neurochemical Sex Differences. Molecules (Basel, Switzerland). vol 27. issue 4. 2022-02-25. PMID:35208969. |
there were no evident changes observed with respect to noradrenaline and serotonin metabolite levels in the male hippocampus. |
2022-02-25 |
2023-08-13 |
mouse |
| Amina E Essawy, Soad Ahmed El-Sayed, Ehab Tousson, Horeya S Abd El-Gawad, Reem Hasaballah Alhasani, Heba-Tallah Abd Elrahim Abd Elkade. Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy. Environmental science and pollution research international. 2022-02-23. PMID:35194715. |
the oxidative stress, antioxidant, and neurochemical parameters, viz., malondialdehyde (mda), nitric oxide (no), reduced glutathione (gsh), superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), acetylcholine esterase (ache), dopamine (da), norepinephrine (ne), and serotonin (5-ht), in the hippocampal and hypothalamic regions have been evaluated. |
2022-02-23 |
2023-08-13 |
rat |
| Qiliang Chen, Candong Li, Enxiang Tao, Tetsuya Asakawa, Yuanyuan Zhan. Exploration of a Brain-Liver-Communication-Related Mechanism Involved in the Experimental Perimenopausal Depression Rat Model using Chaihu-Shugan-San. Neurochemical research. 2022-02-22. PMID:35190952. |
we observed the behavioural performances of depression and anxiety, serum concentrations of biochemical indices, serum estrogen two levels, hippocampal 5-ht and ne levels and the morphological changes in liver tissues. |
2022-02-22 |
2023-08-13 |
rat |
| Alexandre Magno da Nobrega Marinho, Bruno Lobão-Soares, Hugo Alexandre Sousa Targino, Yago José Fernandes Vasconcellos, Ricardo Guarnieri, Carlos Gilberto Carlott. Decreased hippocampal serotonin 5HT Epilepsy & behavior : E&B. vol 129. 2022-02-21. PMID:35189481. |
decreased hippocampal serotonin 5ht mesial temporal lobe epilepsy related to hippocampal sclerosis (mtle-hs) is a surgically remediable epilepsy with a relatively high prevalence and psychiatric comorbidities. |
2022-02-21 |
2023-08-13 |
Not clear |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. |
2022-02-19 |
2023-08-13 |
rat |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
here we aimed to examine the effects of the para- chlorophenylalanine (pcpa; 100mg/kg/daily, s.c during the postnatal days 10-20), a reversible inhibitor of 5-ht synthesis, on the serotonin level of the hippocampal and prefrontal cortex. |
2022-02-19 |
2023-08-13 |
rat |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
our results indicated that the administration of pcpa led to a decrease in serotonin levels in the hippocampus and prefrontal cortex. |
2022-02-19 |
2023-08-13 |
rat |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
postnatal serotonin depletion also induced subtle alterations in the neuronal populations of the hippocampus and impaired spatial memory in the adulthood period of life. |
2022-02-19 |
2023-08-13 |
rat |
| Ying-Xiao Li, Kai-Chun Cheng, Chao-Tien Hsu, Juei-Tang Cheng, Ting-Ting Yan. Major Plant in Herbal Mixture Gan-Mai-Da-Zao for the Alleviation of Depression in Rat Models. Plants (Basel, Switzerland). vol 11. issue 3. 2022-02-15. PMID:35161241. |
the expression levels of the serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) in the hippocampus of the rats with depression were markedly increased by gmdz. |
2022-02-15 |
2023-08-13 |
rat |
| Xiaoyue Wei, Kezhu Wang, Jinfeng Gao, Shijian Chen, Siying Zeng, Yuhong Zha. FG7142 combined with restraint stress induces anxiogenic-like effects via downregulation gamma-aminobutyric acid type A receptor subunit alpha1 and 5-hydroxytryptamine 1A receptors expression in the hippocampus. Neuroreport. vol 33. issue 3. 2022-02-09. PMID:35139062. |
fg7142 combined with restraint stress induces anxiogenic-like effects via downregulation gamma-aminobutyric acid type a receptor subunit alpha1 and 5-hydroxytryptamine 1a receptors expression in the hippocampus. |
2022-02-09 |
2023-08-13 |
Not clear |
| Khalid A El-Saiy, Rabab H Sayed, Ayman E El-Sahar, Esraa A Kandi. Modulation of histone deacetylase, the ubiquitin proteasome system, and autophagy underlies the neuroprotective effects of venlafaxine in a rotenone-induced Parkinson's disease model in rats. Chemico-biological interactions. 2022-02-01. PMID:35104487. |
moreover, venlafaxine hampered depressive symptoms and improved hippocampal noradrenaline and serotonin levels. |
2022-02-01 |
2023-08-13 |
rat |