| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Paula Farias Waltrick, Alvaro Henrique Bernardo de Lima Silva, Milene Cristina de Carvalho, Bruna Aparecida Comotti de Oliveira, Katya Naliwaiko, Joice Maria da Cunha, Janaina Menezes Zanovel. Preventive treatment with fish oil facilitates the antidepressant-like effect of antidepressant drugs in type-1 diabetes mellitus rats: implication of serotonergic system. Neuroscience letters. 2022-01-29. PMID:35090949. |
in addition, confirming these assumptions, the decreased 5-ht levels in the hippocampus from induced-t1dm rats were increased after treatment with flx (highest dose) or imi (both doses), being this increase more pronounced in animal pretreated with fo. |
2022-01-29 |
2023-08-13 |
rat |
| Bingqian Zhou, Ge Jin, Xiaoqi Pang, Qi Mo, Jie Bao, Tiaotiao Liu, Jingyi Wu, Runxiang Xie, Xiang Liu, Jinghua Liu, Hongwei Yang, Xin Xu, Bangmao Wang, Hailong Ca. Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood. Pharmacological research. 2022-01-22. PMID:35065201. |
mechanically, lgg colonization activated epithelial growth factor receptor (egfr) and enhanced serotonin transporter (sert) expression and modulated serotonergic system in the intestine, and increased brain-derived neurotrophic factor and γ-aminobutyric acid receptor levels in the hippocampus and amygdala. |
2022-01-22 |
2023-08-13 |
mouse |
| Qi Wang, Ya-Nan Sun, Chun-Ming Zou, Te-Li Zhang, Zhu Li, Min Liu, Bi-Ying Shi, Shan-Shan Shi, Chun-Yue Yu, Tai-Ming We. Regulation of the kynurenine/serotonin pathway by berberine and the underlying effect in the hippocampus of the chronic unpredictable mild stress mice. Behavioural brain research. 2022-01-20. PMID:35051489. |
this study was to investigate the hypothesis that bbr treats depressive-like behavior by shifting the balance of the kynurenine (kyn)/serotonin (5-ht) pathway toward the 5-ht pathway through downregulated indoleamine 2,3-dioxygenase 1 (ido1), monoamine oxidase a (maoa) and upregulated dopamine decarboxylase (ddc) in hippocampus. |
2022-01-20 |
2023-08-13 |
mouse |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
liquid chromatography-tandem mass spectrometry(lc-ms/ms) was used to detect the levels of dopamine(da), 5-hydroxytryptamine(5-ht), and norepinephrine(ne) in the hippocampus and serum of mice. |
2022-01-07 |
2023-08-13 |
mouse |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
in the hippocampus and serum, the levels of il-1β, il-6, tnf-α, and mda were increased(p<0.01), and the activity of sod and the levels of gsh, da, 5-ht, ne, and bdnf were reduced(p<0.01). |
2022-01-07 |
2023-08-13 |
mouse |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
the treatment with high-dose jiaotai pills increased the sucrose preference rate, movement distance, and the number of crossing centers(p<0.05), reduced tail suspension time and swimming immobility time(p<0.01), elevated hippocampal sirt1 expression level(p<0.01), decreased hippocampal and serum il-1β, il-6, tnf-α, and mda levels(p<0.01), potentiated sod activity, and up-regulated gsh, da, 5-ht, ne, and bdnf levels in the hippocampus and serum(p<0.05, p<0.01) in model mice. |
2022-01-07 |
2023-08-13 |
mouse |
| Xueting Zhang, Kazufumi Yoshihara, Noriyuki Miyata, Tomokazu Hata, Altanzul Altaisaikhan, Shu Takakura, Yasunari Asano, Satoshi Izuno, Nobuyuki Sud. Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice. Physiology & behavior. vol 244. 2021-12-11. PMID:34800493. |
the ttp-deprived group showed a reduction in ttp levels in the serum, concomitant with decreases in both phenylalanine and tyrosine levels in the hippocampus, as well as serotonin, norepinephrine, and dopamine concentrations in some regions of the brain. |
2021-12-11 |
2023-08-13 |
mouse |
| Tatiana de Queiroz Oliveira, Adriano José Maia Chaves Filho, Paloma Marinho Jucá, Michelle Verde Ramos Soares, Natássia Lopes Cunha, Charliene Freire Xavier Vieira, Carlos Venício Jataí Gadelha Filho, Glautemberg de Almeida Viana, Gabriela Mariângela Farias De Oliveira, Danielle Silveira Macedo, Silvânia Maria Mendes Vasconcelo. Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression. Behavioural brain research. vol 419. 2021-12-10. PMID:34798169. |
also, hippocampus (hc) protein expression of the serotonin transporter (sert), synaptophysin, protein kinase b-akt (total and phosphorylated) and the cytokines il-4 and il-6 were investigated. |
2021-12-10 |
2023-08-13 |
mouse |
| Nirupa Goel, Tristan J Philippe, Judy Chang, Maya E Koblanski, Victor Via. Cellular and serotonergic correlates of habituated neuroendocrine responses in male and female rats. Psychoneuroendocrinology. vol 136. 2021-12-10. PMID:34891046. |
relative to their singly restrained counterparts, males displayed an increase in 5-ht 1 a receptor expression in the raphe nucleus after repeated restraint, whereas females showed a decrease in 5-ht 1 a mrna levels in the hippocampus and in the zona incerta, representing the most proximal of cell groups expressing the 5-ht 1 a receptor in the vicinity of the pvh. |
2021-12-10 |
2023-08-13 |
rat |
| Maria Sidorova, Golo Kronenberg, Susann Matthes, Markus Petermann, Rainer Hellweg, Oksana Tuchina, Michael Bader, Natalia Alenina, Friederike Klempi. Enduring Effects of Conditional Brain Serotonin Knockdown, Followed by Recovery, on Adult Rat Neurogenesis and Behavior. Cells. vol 10. issue 11. 2021-12-07. PMID:34831469. |
serotonin (5-hydroxytryptamine, 5-ht) is a crucial signal in the neurogenic niche of the hippocampus, where it is involved in antidepressant action. |
2021-12-07 |
2023-08-13 |
rat |
| Lu Wang, Min Zhang, Jing Wen, Yalan Xiang, Xiaoyu Duan, Changwei Yu, Miao Yan, Bikui Zhang, Pingfei Fan. Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats. Frontiers in pharmacology. vol 12. 2021-12-07. PMID:34867385. |
the concentration of monoamines, amino acids, and choline neurotransmitters, the dopamine (da) and 5-hydroxytryptamine (5-ht) metabolic pathway in the hippocampus, cerebellum, striatum, prefrontal cortex, hypothalamus, serum, and plasma were detected by lc-ms/ms. |
2021-12-07 |
2023-08-13 |
rat |
| Guanlong Guo, Jiaxin Tang, Mengwen Shi, Chengmei Yang, Huaxing Ou, Weihai Che. MK212, a 5-hydroxytryptamine 2C receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 113. 2021-12-06. PMID:34560172. |
mk212, a 5-hydroxytryptamine 2c receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus. |
2021-12-06 |
2023-08-13 |
Not clear |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
in addition, semen sojae praeparatum significantly promoted the contents of norepinephrine (ne), 5-hydroxytryptamine (5-ht), brain-derived neurotrophic factor (bdnf), and gamma-aminobutyric acid (gaba) in the hippocampus and the content of bdnf in the serum (p < 0.05). |
2021-12-05 |
2023-08-13 |
rat |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
genus ruminococcaceae_ucg-008 was positively correlated with gaba and bdnf levels in the hippocampus; genus lactobacillus had a positive correlation with 5-ht; and genus bacteroides had negative correlations with 5-ht, bdnf, and ne. |
2021-12-05 |
2023-08-13 |
rat |
| Mariana Angoa-Pérez, Branislava Zagorac, Dina M Francescutti, Kevin R Theis, Donald M Kuh. Responses to chronic corticosterone on brain glucocorticoid receptors, adrenal gland, and gut microbiota in mice lacking neuronal serotonin. Brain research. vol 1751. 2021-11-30. PMID:33152342. |
neuronal 5ht depletion impaired the feedback regulation of cort levels but had no putative effect on the cort-induced decrease in hippocampal gr expression and the reduction of the adrenal cortex size. |
2021-11-30 |
2023-08-13 |
mouse |
| Jae Heon Kim, Young Soo Ahn, Yun Seob Son. Serotonin Discharge Regulation by Additional Neurotransmitters of Rat Hippocampus Associated With the Continence Central Circuit. International neurourology journal. vol 25. issue Suppl 2. 2021-11-30. PMID:34844393. |
serotonin discharge regulation by additional neurotransmitters of rat hippocampus associated with the continence central circuit. |
2021-11-30 |
2023-08-13 |
rat |
| Jae Heon Kim, Young Soo Ahn, Yun Seob Son. Serotonin Discharge Regulation by Additional Neurotransmitters of Rat Hippocampus Associated With the Continence Central Circuit. International neurourology journal. vol 25. issue Suppl 2. 2021-11-30. PMID:34844393. |
in order to advance knowledge of how serotoninergic neurons and additional nerve fibers were correlated, the purpose of the present work was to research how the discharge of serotonin from hippocampal slices was affected by different neurotransmitters in rat models. |
2021-11-30 |
2023-08-13 |
rat |
| Jae Heon Kim, Young Soo Ahn, Yun Seob Son. Liberation of Serotonin Is Not Unaffected by Acetylcholine in Rat Hippocampus. International neurourology journal. vol 25. issue Suppl 2. 2021-11-30. PMID:34844394. |
liberation of serotonin is not unaffected by acetylcholine in rat hippocampus. |
2021-11-30 |
2023-08-13 |
rat |
| Jae Heon Kim, Young Soo Ahn, Yun Seob Son. Liberation of Serotonin Is Not Unaffected by Acetylcholine in Rat Hippocampus. International neurourology journal. vol 25. issue Suppl 2. 2021-11-30. PMID:34844394. |
the current research was conducted in order to explore the role of acetylcholine in serotonin liberation from sections of rat hippocampus in order to improve the comprehension of the relationship between cholinergic and serotonergic neurons. |
2021-11-30 |
2023-08-13 |
rat |
| Meira Maria Forcelini Machado, Renata Mancini Banin, Fernanda Malanconi Thomaz, Iracema Senna de Andrade, Valter Tadeu Boldarine, Jéssica de Souza Figueiredo, Bruna Kelly Sousa Hirata, Lila Missae Oyama, João Henrique Ghilardi Lago, Eliane Beraldi Ribeiro, Mônica Marques Telle. Ginkgo biloba Extract (GbE) Restores Serotonin and Leptin Receptor Levels and Plays an Antioxidative Role in the Hippocampus of Ovariectomized Rats. Molecular neurobiology. vol 58. issue 6. 2021-11-24. PMID:33492645. |
ginkgo biloba extract (gbe) restores serotonin and leptin receptor levels and plays an antioxidative role in the hippocampus of ovariectomized rats. |
2021-11-24 |
2023-08-13 |
rat |