| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristiano Bombardi, Annamaria Grandis, Nela Pivac, Marina Sagud, Guillaume Lucas, Abdeslam Chagraoui, Valérie Lemaire-Mayo, Philippe De Deurwaerdère, Giuseppe Di Giovann. Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics. Progress in brain research. vol 261. 2021-10-22. PMID:33785139. |
for this reason, we review reported data concerning the distribution and the functional roles of the 5-ht receptors in the hippocampal region in health and disease. |
2021-10-22 |
2023-08-13 |
Not clear |
| Cristiano Bombardi, Annamaria Grandis, Nela Pivac, Marina Sagud, Guillaume Lucas, Abdeslam Chagraoui, Valérie Lemaire-Mayo, Philippe De Deurwaerdère, Giuseppe Di Giovann. Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics. Progress in brain research. vol 261. 2021-10-22. PMID:33785139. |
the impact of the 5-ht systems on the hippocampal function is such that the research of new 5-ht mechanisms and drugs is still very active. |
2021-10-22 |
2023-08-13 |
Not clear |
| Tori L Schaefer, Curtis E Grace, Matthew R Skelton, Devon L Graham, Gary A Gudelsky, Charles V Vorhees, Michael T William. Neonatal citalopram treatment inhibits the 5-HT depleting effects of MDMA exposure in rats. ACS chemical neuroscience. vol 3. issue 1. 2021-10-21. PMID:22582138. |
we have previously showed that mdma exposure (4×10 mg/kg/day) from p11-20 (analogous to human third trimester exposure) induces ~50% decreases in hippocampal 5-ht throughout treatment. |
2021-10-21 |
2023-08-12 |
human |
| Tori L Schaefer, Curtis E Grace, Matthew R Skelton, Devon L Graham, Gary A Gudelsky, Charles V Vorhees, Michael T William. Neonatal citalopram treatment inhibits the 5-HT depleting effects of MDMA exposure in rats. ACS chemical neuroscience. vol 3. issue 1. 2021-10-21. PMID:22582138. |
in a series of experiments we evaluated the effects of different doses and dose regimens of cit on mdma-induced 5-ht depletions in three brain regions (hippocampus, entorhinal cortex, and neostriatum) at three time-points (p12, p16, p21) during the treatment interval (p11-20) known to induce behavioral alterations when animals are tested as adults. |
2021-10-21 |
2023-08-12 |
human |
| Xiao-Wei Ji, Chun-Ling Wu, Xing-Chen Wang, Jie Liu, Jian-Zhong Bi, Dian-Yun Wan. Monoamine neurotransmitters and fibroblast growth factor-2 in the brains of rats with post-stroke depression. Experimental and therapeutic medicine. vol 8. issue 1. 2021-10-21. PMID:24944615. |
high-performance liquid chromatography was used to detect the levels of 5-ht, da and ne, while western blotting was used to detect the fgf-2 protein expression levels in the frontal lobe and hippocampus. |
2021-10-21 |
2023-08-13 |
rat |
| Xiao-Wei Ji, Chun-Ling Wu, Xing-Chen Wang, Jie Liu, Jian-Zhong Bi, Dian-Yun Wan. Monoamine neurotransmitters and fibroblast growth factor-2 in the brains of rats with post-stroke depression. Experimental and therapeutic medicine. vol 8. issue 1. 2021-10-21. PMID:24944615. |
the levels of 5-ht, da and ne in the frontal lobe and hippocampus of the rats in the psd group were significantly lower than the levels observed in the rats in the stroke group (p<0.01). |
2021-10-21 |
2023-08-13 |
rat |
| Asia Afzal, Zehra Batool, Sadia Sadir, Laraib Liaquat, Sidrah Shahzad, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Tahira Perveen, Saida Haide. Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34409523. |
in addition to this, high corticosterone levels and decreased hippocampal bdnf, 5-ht, dopamine (da), and acetylcholine (ach) levels were also observed in depressed animals. |
2021-10-21 |
2023-08-13 |
rat |
| Stanislava Bukatova, Emese Renczes, Alexandra Reichova, Johan Filo, Anna Sadlonova, Boris Mravec, Daniela Ostatnikova, Jan Bakos, Zuzana Bacov. Shank3 Deficiency is Associated With Altered Profile of Neurotransmission Markers in Pups and Adult Mice. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34453663. |
our research found enhanced expression of serotonin transporter and choline acetyltransferase in the hippocampus and hypothalamus in shank3-deficient pups. |
2021-10-21 |
2023-08-13 |
mouse |
| Shuiyu Lu, Jeih-San Liow, Sami S Zoghbi, Jinsoo Hong, Robert B Innis, Victor W Pik. Evaluation of [C]S14506 and [F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors. Current radiopharmaceuticals. vol 3. issue 1. 2021-10-20. PMID:20657759. |
the ratios of radioactivity in 5-ht(1a) receptor-rich regions, such as cingulate or hippocampus to that in receptor-poor cerebellum reached between 1.35 and 1.5 at 60 min for both [(11)c]s14506 and [(18)f]s14506. |
2021-10-20 |
2023-08-12 |
rat |
| Ainitze Labaka, Eneritz Gómez-Lazaro, Olatz Goñi-Balentziaga, Joana Pérez-Tejada, Oscar Vegas, Larraitz Garmendi. Venlafaxine reduces the striatal il6/il10 ratio and increases hippocampal GR expression in female mice subjected to chronic social instability stress. Stress (Amsterdam, Netherlands). vol 24. issue 5. 2021-10-20. PMID:33769212. |
they also had lower levels of 5-ht, 5-hiaa and na and a higher kyn/tryp ratio in the hippocampus. |
2021-10-20 |
2023-08-13 |
mouse |
| Yanpo Si, Xiaohui Chen, Tao Guo, Wenjun Wei, Lili Wang, Fei Zhang, Xiaoya Sun, Mengqi Li. Comprehensive 16S rDNA Sequencing and LC-MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine-Induced Insomnia Rats Treated with Lilium brownie. Neurochemical research. 2021-10-18. PMID:34661797. |
it was also found that the most of metabolic phenotypes in serum, hypothalamus and hippocampus perturbed by pcpa were regulated towards normal after lb intervention, especially 5-hydroxy-l-tryptophan of the hypothalamus involving in 5-ht metabolism. |
2021-10-18 |
2023-08-13 |
rat |
| Xiaoyu Pan, Ling Chen, Wen Xu, Shihui Bao, Jun Wang, Xiao Cui, Shichao Gao, Kaiping Liu, Shivani Avasthi, Meixi Zhang, Ruijie Che. Activation of monoaminergic system contributes to the antidepressant- and anxiolytic-like effects of J147. Behavioural brain research. vol 411. 2021-10-18. PMID:34023306. |
in neurochemical assays, studies suggested that serotonin and noradrenaline levels were significantly increased in the frontal cortex and hippocampus after treatment of j147 by the high-performance liquid chromatography (hplc) with an electrochemical detector. |
2021-10-18 |
2023-08-13 |
mouse |
| Xiwen Geng, Hongyun Wu, Zifa Li, Chuanfen Li, Dan Chen, Jiancheng Zong, Zimin Liu, Sheng Wei, Wei Pen. Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway. Oxidative medicine and cellular longevity. vol 2021. 2021-10-15. PMID:34646421. |
in the hippocampus and prefrontal cortex, concentrations of 5-ht and its metabolite 5-hydroxyindoleacetic acid, as well as monoamine oxidase a, glucocorticoid receptor, and 5-ht1a receptor expression levels, were measured. |
2021-10-15 |
2023-08-13 |
rat |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
following nor and epm testing hippocampal norepinephrine (ne), 5, hydroxytryptamine (5-ht), 5, hydroxyindole acetic acid (5-hiaa), corticosterone (cort) and interleukin-6 (il-6) were determined and serum collected for basal cort analysis. |
2021-10-13 |
2023-08-13 |
mouse |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
si impaired performance in the nor and the fst, reduced hippocampal 5-ht, increased hippocampal il-6 and increased serum cort post-fst in young mice. |
2021-10-13 |
2023-08-13 |
mouse |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
aged mice either failed to respond significantly to si (nor, fst, hippocampal 5-ht, serum cort post fst) or si had synergistic effects with age (hippocampal ne, 5-hiaa:5-ht). |
2021-10-13 |
2023-08-13 |
mouse |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
chronic escitalopram treatment does not alter the effects of neonatal stress on hippocampal bdnf levels, 5-ht early life stress is considered a risk factor for the development of long-term psychiatric disorders. |
2021-10-13 |
2023-08-13 |
Not clear |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
the goal of the present study was to examine the effects of a chronic treatment with escitalopram (esc) on the hippocampal levels of bdnf and neuropeptide y (npy), expression of serotonin type 1a receptor (5-ht |
2021-10-13 |
2023-08-13 |
Not clear |
| Wenting Fang, Naian Xiao, Guirong Zeng, Daode Bi, Xiaoman Dai, Xue Mi, Qinyong Ye, Xiaochun Chen, Jing Zhan. APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34611141. |
furthermore, apoe4 increased stress-induced depression-like behaviors, accompanied by declines in the hippocampal 5-ht (1a) radioligand [18f] mppf uptake evidenced by positron emission tomography (pet). |
2021-10-11 |
2023-08-13 |
mouse |
| Ekram Nemr Abd Al Haleem, Hebatalla I Ahmed, Reem N El-Nag. Lycopene and Chrysin through Mitigation of Neuroinflammation and Oxidative Stress Exerted Antidepressant Effects in Clonidine-Induced Depression-like Behavior in Rats. Journal of dietary supplements. 2021-10-11. PMID:34633271. |
lycopene and chrysin were used to correct the concentrations of noradrenaline and serotonin hippocampal tissue concentrations. |
2021-10-11 |
2023-08-13 |
rat |