All Relations between hippocampus and serotonin

Publication Sentence Publish Date Extraction Date Species
Felipe de Jesus Jiménez Vásquez, Diana Méndez Guerrero, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350985. these data show that behavioural disruption caused by prenatal stress is related to low release and lower metabolism of serotonin in the ventral hippocampus in adult male offspring, as well as to hyperactivity and hyperreactivity of the adrenal axis. 2021-09-30 2023-08-13 rat
Diana Méndez Guerrero, Felipe de Jesus Jiménez Vásquez, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350993. serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. 2021-09-30 2023-08-13 rat
Diana Méndez Guerrero, Felipe de Jesus Jiménez Vásquez, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350993. it is currently unknown whether prenatal stress modifies serotonin (5-ht) and noradrenaline (na) content and their release in the hippocampus during cognitive performance. 2021-09-30 2023-08-13 rat
Diana Méndez Guerrero, Felipe de Jesus Jiménez Vásquez, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350993. after cognitive tests, the dorsal hippocampus was dissected to quantify 5-ht and na content. 2021-09-30 2023-08-13 rat
Diana Méndez Guerrero, Felipe de Jesus Jiménez Vásquez, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350993. in other males, 5-ht and na release in the dorsal hippocampus was assessed by microdialysis, before and after cognitive tests. 2021-09-30 2023-08-13 rat
Diana Méndez Guerrero, Felipe de Jesus Jiménez Vásquez, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Serotonin and noradrenaline content and release in the dorsal hippocampus during learning and spatial memory in prenatally stressed rats. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350993. hippocampal 5-ht content decreased during learning and memory tasks in both groups, while na content was not modified in prenatally stressed males neither before, nor after learning and memory tests. 2021-09-30 2023-08-13 rat
Megumi Furukawa, Nobuo Izumo, Takayuki Manabe, Haruna Kurono, Kohsuke Hayamizu, Makoto Nakano, Yasuo Watanab. Therapeutic effects of sertraline on improvement of Ovariectomy-induced decreased spontaneous activity in mice. Drug discoveries & therapeutics. vol 15. issue 1. 2021-09-17. PMID:33627575. these results suggest that sertraline improves the decrease in spontaneous activity induced by ovx assessed by the hippocampus suppressing decreased serotonin synthesis in the serotonergic neuron. 2021-09-17 2023-08-13 mouse
Mahesh Bekal, Lue Sun, Susumu Ueno, Takashi Moritak. Neurobehavioral effects of acute low-dose whole-body irradiation. Journal of radiation research. vol 62. issue 5. 2021-09-16. PMID:33982114. a serotonin (5-ht), dopamine, gamma-aminobutyric acid (gaba) and cortisol analysis was carried out in blood, hippocampus, amygdala and whole brain tissue. 2021-09-16 2023-08-13 mouse
Yinhua Ni, Luting Hu, Song Yang, Liyang Ni, Lingyan Ma, Yufeng Zhao, Aqian Zheng, Yuanxiang Jin, Zhengwei F. Bisphenol A impairs cognitive function and 5-HT metabolism in adult male mice by modulating the microbiota-gut-brain axis. Chemosphere. vol 282. 2021-09-06. PMID:34082316. the levels of neurotransmitters in the serum, hippocampus, and colon of male mice, including tryptophan, 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid, were all decreased by bpa, together with reduced expression of tryptophan and 5-ht metabolism-related genes. 2021-09-06 2023-08-13 mouse
Vergine Chavushyan, Senik Matinyan, Margarita Danielyan, Michail Aghajanov, Konstantin Yenkoya. Embryonic proteoglycans regulate monoamines in the rat frontal cortex and hippocampus in Alzheimer's disease-like pathology. Neurochemistry international. vol 140. 2021-09-02. PMID:32853753. results showed that the levels of monoamines and especially norepinephrine in the target ad brain structures were found elevated, except serotonin, which was unaffected in the hippocampus, but decreased in the frontal cortex. 2021-09-02 2023-08-13 rat
Oliver Stiedl, Eugenia Kuteeva, Tomas Hökfelt, Sven Ove Ögre. Injection of galanin into the dorsal hippocampus impairs emotional memory independent of 5-HT Behavioural brain research. vol 405. 2021-09-02. PMID:33607166. injection of galanin into the dorsal hippocampus impairs emotional memory independent of 5-ht there is evidence that interaction between the neuropeptide galanin and the 5-ht 2021-09-02 2023-08-13 Not clear
Vibe G Frokjae. Pharmacological sex hormone manipulation as a risk model for depression. Journal of neuroscience research. vol 98. issue 7. 2021-08-26. PMID:32399989. the gnrha model work points to an estradiol-dependent depressive response in healthy women undergoing short-term sex hormone manipulation with gnrha, which is linked to serotonin transporter changes (a key regulator of synaptic serotonin), a disengagement of hippocampus, and overengagement of brain networks recruited when processing emotional salient information. 2021-08-26 2023-08-13 human
Noreen Samad, Farheen Hafeez, Imran Imra. D-galactose induced dysfunction in mice hippocampus and the possible antioxidant and neuromodulatory effects of selenium. Environmental science and pollution research international. 2021-08-23. PMID:34424474. the neurochemical assessment showed that d-gal-induced increased serotonin metabolism and decreased acetylcholine levels in the hippocampus were restored by repeated treatment of se. 2021-08-23 2023-08-13 mouse
Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. serotonin 5-ht7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of fragile x syndrome. 2021-08-18 2023-08-13 mouse
Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. we have previously demonstrated that activation of serotonin 5-ht7 receptors reverses mglur-ltd in the hippocampus of wild-type and fmr1 ko mice, thus correcting a synaptic dysfunction typically observed in this disease model. 2021-08-18 2023-08-13 mouse
He Yu, Zhong-Mei He, Kun Shi, Yan Zhao, Ying Zong, Jian-Ming Li, Wei-Jia Chen, Rui D. [Study on antidepressant effect of total alkaloids of Fibraurea recisa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 14. 2021-08-18. PMID:34402292. this study aimed to investigate the antidepressant effects of total alkaloids of fibraurea recisa in ht22 cells damaged by corticosterone (cort) in vitro and in a mouse model of chronic unpredictable mild stress (cums) as well as the underlying mechanisms.in cellular experiments,the viability of cort-damaged ht22 cells was detected using cell counting kit-8 (cck-8),and the cell apoptosis was detected by hoechst 33258 staining.in animal experiments,c57bl/6n mice were randomly divided into the control group,model group,low (100 mg·kg~(-1)),medium (200 mg·kg~(-1)) and high (400 mg·kg~(-1))-dose of total alkaloids of f.recisa groups,and positive control group.after 21 days of cums exposure,their depressive behaviors were observed in behavioral and morris water maze tests.the serum levels of 5-hydroxytryptamine (5-ht),dopamine (da),and norepinephrine (ne) were assessed by elisa.the expression levels of apoptosis-related proteins bcl-2,bax and cleaved caspase-3 in ht22 cells and mouse hippocampus were detected by western blot.the results suggested that total alkaloids of f.recisa alleviated the damage of ht22 cells induced by cort in a dose-dependent manner.the hoechst 33258 staining uncovered that total alkaloids of f.recisa better reduced the blue spots and inhibited cell apoptosis.the results of animal experiments showed that total alkaloids of f.recisa significantly improved the depression-like behaviors of mice and increased the serum levels of 5-ht,da and ne as compared with those in the model group.the western blot assays revealed a significant up-regulation of bcl-2 protein expression,but an obvious reduction in bax and cleaved caspase-3protein expression in the total alkaloids of f.recisa group.in conclusion,total alkaloids of f.recisa inhibited depression possibly by regulating the apoptosis-related protein expression or elevating the monoamine neurotransmitter levels in the brain. 2021-08-18 2023-08-13 mouse
Claudia Villani, Giuseppina Sacchetti, Mirjana Carli, Roberto W Invernizz. Fluoxetine rescues rotarod motor deficits in Mecp2 heterozygous mouse model of Rett syndrome via brain serotonin. Neuropharmacology. vol 176. 2021-08-13. PMID:32652084. mecp2 null mice, which responded poorly to fluoxetine in the rotarod, showed reduced 5-ht synthesis in the prefrontal cortex, hippocampus and striatum, and reduced efficacy of fluoxetine in raising extracellular 5-ht as compared to female mutants. 2021-08-13 2023-08-13 mouse
Jun-Qi Yao, Chang Liu, Zeng-Liang Jin, Yan-Qin Liu, Yong-Yu Yin, Xin-Xin Fang, Yu-Hua Ran, Li-Ming Zhang, Yun-Feng L. Serotonergic transmission is required for the anxiolytic-like behavioral effects of YL-IPA08, a selective ligand targeting TSPO. Neuropharmacology. vol 178. 2021-08-12. PMID:32693005. furthermore, we found that yl-ipa08 increased the extracellular levels of 5-ht in the rat ventral hippocampus in freely moving rat using the rapid and validated hplc coupled with microdialysis. 2021-08-12 2023-08-13 mouse
Zhicheng Jin, Jianer Ling, Jing Yu, Mengzi He, Pingping Ni, Fang Zhang, Yizhen Wan. Serotonin 2A receptor function and depression-like behavior in rats model of hypothyroidism. Experimental brain research. vol 239. issue 8. 2021-08-12. PMID:34106297. tt[formula: see text] and tt[formula: see text] levels were measured after the behavior tests and the expression levels of 5-ht[formula: see text] receptor and 5-ht[formula: see text] receptor proteins were analyzed in the hippocampus and prefrontal cortex. 2021-08-12 2023-08-13 rat
Rachel E Martin, Madison T Green, Jessica A Kinkade, Robert R Schmidt, Tess E Willemse, A Katrin Schenk, Jiude Mao, Cheryl S Rosenfel. Maternal Oxycodone Treatment Results in Neurobehavioral Disruptions in Mice Offspring. eNeuro. vol 8. issue 4. 2021-08-12. PMID:34312305. in the hippocampus, prenatal exposure to oxy caused sex-dependent differences in expression of genes encoding opioid receptors and those involved in serotonin signaling. 2021-08-12 2023-08-13 mouse