All Relations between hippocampus and serotonin

Reference Sentence Publish Date Extraction Date Species
Fritz Kobe, Daria Guseva, Thomas P Jensen, Alexander Wirth, Ute Renner, Dietmar Hess, Michael M\\xc3\\xbcller, Lucian Medrihan, Weiqi Zhang, Mingyue Zhang, Katharina Braun, S\\xc3\\xb6ren Westerholz, Andreas Herzog, Konstantin Radyushkin, Ahmed El-Kordi, Hannelore Ehrenreich, Diethelm W Richter, Dmitri A Rusakov, Evgeni Ponimaski. 5-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 32 issue 9 2012 22378867 here we report that activation of the serotonin 5-ht(7) receptor promotes synaptogenesis and enhances synaptic activity in hippocampal neurons at early postnatal stages. 2012-04-20 2022-01-12 Not clear
V M Piccolini, S Cerri, E Romanelli, G Bernocch. Interactions of neurotransmitter systems during postnatal development of the rat hippocampal formation: effects of cisplatin. Experimental neurology vol 234 issue 1 2012 22245617 the distribution of neuroimmunohistochemical markers for the serotoninergic, noradrenergic, glutamatergic and gabaergic systems (respectively, 5ht(2a)r, \xce\xb21ar, glur 2/3 and gad65/67) was determined in the hippocampal formation at stages pd11, pd17 and pd30 of postnatal development of untreated rats and cisplatin-treated rats after a single injection of the drug at 10days of life. 2012-04-19 2022-01-12 Not clear
Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schi\\xc3\\xb6th, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides vol 32 issue 11 2012 21820473 taking in mint these evidences, we studied the release of radioactive 5-ht to the superfusion medium from hippocampal slices treated with two doses of ghr (0.3 and 3 nm/\xce\xbcl). 2012-04-16 2022-01-12 Not clear
Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Giuseppa Mud\\xc3\\xb3, Mileidys P\\xc3\\xa9rez-Alea, Francisco Ciruela, Alexander O Tarakanov, Manuel Narvaez, Valentina Di Liberto, Luigi F Agnati, Natale Belluardo, Kjell Fux. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological psychiatry vol 71 issue 1 2012 22035699 fibroblast growth factor receptor 1- 5-hydroxytryptamine 1a heteroreceptor complexes and their enhancement of hippocampal plasticity. 2012-03-30 2022-01-12 Not clear
Seung-Soo Baek, Tae-Won Jun, Ki-Jeong Kim, Mal-Soon Shin, Sun-Young Kang, Chang-Ju Ki. Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups. Brain & development vol 34 issue 1 2012 21353411 in this study, we investigated the effects of postnatal treadmill exercise on the long-term memory capability, spatial learning ability, and depressive state, on the 5-hydroxytryptamine (5-ht, serotonin) synthesis and tryptophan hydroxylase (tph) expression in the dorsal raphe nuclei, and on the apoptosis and cell proliferation in the hippocampal dentate gyrus of rat pups following maternal separation. 2012-03-30 2022-01-12 Not clear
Seung-Soo Baek, Tae-Won Jun, Ki-Jeong Kim, Mal-Soon Shin, Sun-Young Kang, Chang-Ju Ki. Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups. Brain & development vol 34 issue 1 2012 21353411 the 5-ht synthesis and tph expression in the dorsal raphe nuclei and cell proliferation in the hippocampal dentate gyrus were significantly decreased in the maternal-separated rat pups, and postnatal treadmill exercise increased 5-ht synthesis, the tph expression, and the cell proliferation. 2012-03-30 2022-01-12 Not clear
J H Meye. Neuroimaging markers of cellular function in major depressive disorder: implications for therapeutics, personalized medicine, and prevention. Clinical pharmacology and therapeutics vol 91 issue 2 2012 22218074 neuroimaging of monoamine oxidase-a (mao-a) binding; glutamate levels; indexes of 5-ht(2a), 5-htt, 5-ht(1a), and 5-ht(1b) receptors; levels of dopamine transporters d(1) and d(2); and hippocampal volume are described here. 2012-03-20 2022-01-12 Not clear
Ouissame Mnie-Filali, C\\xc3\\xa9line Faure, Laura Lamb\\xc3\\xa1s-Se\\xc3\\xb1as, Mostafa El Mansari, Hassina Belblidia, Elise Gondard, Adeline Eti\\xc3\\xa9vant, H\\xc3\\xa9l\\xc3\\xa8ne Scarna, Anne Didier, Anne Berod, Pierre Blier, Nasser Haddjer. Pharmacological blockade of 5-HT7 receptors as a putative fast acting antidepressant strategy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 36 issue 6 2012 21326194 in contrast with fluoxetine, a 1-week treatment with sb-269970 did not alter 5-ht firing activity but desensitized cell body 5-ht autoreceptors, enhanced the hippocampal cell proliferation, and counteracted the depressive-like behavior in olfactory bulbectomized rats. 2012-02-09 2022-01-12 Not clear
Gregory C Hadlock, Katy M Webb, Lisa M McFadden, Pei Wen Chu, Jonathan D Ellis, Scott C Allen, David M Andrenyak, Paula L Vieira-Brock, Christopher L German, Kevin M Conrad, Amanda J Hoonakker, James W Gibb, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. 4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. The Journal of pharmacology and experimental therapeutics vol 339 issue 2 2012 21810934 results revealed that, similar to methylenedioxymethamphetamine, methamphetamine, and methcathinone, repeated mephedrone injections (4\xc3\x97 10 or 25 mg/kg s.c. per injection, 2-h intervals, administered in a pattern used frequently to mimic psychostimulant "binge" treatment) cause a rapid decrease in striatal dopamine (da) and hippocampal serotonin (5-hydroxytryptamine; 5ht) transporter function. 2012-01-16 2022-01-12 Not clear
C Nothdurfter, S Tanasic, G Rammes, R Rupprech. Modulation of ligand-gated ion channels as a novel pharmacological principle. Pharmacopsychiatry vol 44 Suppl 1 issue 2011 21544743 electrophysiological recordings of 5-ht evoked cation currents were recorded with n1e-115 and hek-5-ht (3a) cells and hippocampal neurons. 2011-12-19 2022-01-12 Not clear
Sven Parkel, Lauri T\\xc3\\xb5ntson, Ago Rinke. Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins. Neurotoxicology vol 32 issue 1 2011 21126535 in the present report we have studied the influence of mn(2+) on 5-ht(1a) receptor signaling complexes in rat brain and found that mn(2+) in millimolar concentration caused an increase of high-affinity agonist binding to rat hippocampal membranes in comparison with experiments in the presence of mg(2+), but not in rat cortical membranes and in sf9 cell membranes expressing 5-ht(1a) receptors and g(i1) heterotrimers. 2011-12-09 2022-01-12 Not clear
Sven Parkel, Lauri T\\xc3\\xb5ntson, Ago Rinke. Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins. Neurotoxicology vol 32 issue 1 2011 21126535 activation of g proteins with 30\xce\xbcm gtp\xce\xb3s turned all 5-ht(1a) receptors in these preparations into a low-affinity state for agonist binding in the presence of 1mm mg(2+), but not in the presence of 1mm mn(2+) in rat hippocampal membranes. 2011-12-09 2022-01-12 Not clear
Tamaki Nagata, Atsuko Nishiyama, Takako Yamato, Toshio Obata, Masahiro Aomin. Diabetes modulates ethanol-induced increase in serotonin release from rat hippocampus: an in vivo microdialysis study. Nutritional neuroscience vol 14 issue 3 2011 21756530 hippocampal 5-ht was measured by using in vivo microdialysis. 2011-11-21 2022-01-12 Not clear
Martin Egeland, Jennifer Warner-Schmidt, Paul Greengard, Per Svenningsso. Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum. Neuropharmacology vol 61 issue 3 2011 21300076 in the caudate-putamen, the hippocampal pyramidal cell layer of ca1 and the hippocampal granule cell layer of dentate gyrus, most p11 containing cells co-expressed both 5-ht(1b)r and 5-ht(4)r. in the cingulate cortex, stratum radiatum/oriens of ca1, hilus of the dentate gyrus and cerebellar cortex, many cells co-expressed p11 and 5-ht(1b)r, but not 5-ht(4)r. in the studied brain regions, few cells solely expressed p11 without any significant expression of 5-ht(1b)r or 5-ht(4)r. it can be concluded that p11 is anatomically positioned to modulate serotonin neurotransmission, via 5-ht(1b)r and 5-ht(4)r, in brain regions important for emotionality, cognition and locomotion. 2011-10-14 2022-01-12 Not clear
Wendy Adams, Maarten van den Buus. Hippocampal serotonin depletion facilitates the enhancement of prepulse inhibition by risperidone: possible role of 5-HT(2C) receptors in the dorsal hippocampus. Neuropharmacology vol 61 issue 3 2011 21477601 hippocampal serotonin depletion facilitates the enhancement of prepulse inhibition by risperidone: possible role of 5-ht(2c) receptors in the dorsal hippocampus. 2011-10-14 2022-01-12 Not clear
Wendy Adams, Maarten van den Buus. Hippocampal serotonin depletion facilitates the enhancement of prepulse inhibition by risperidone: possible role of 5-HT(2C) receptors in the dorsal hippocampus. Neuropharmacology vol 61 issue 3 2011 21477601 selective upregulation of 5-ht(2c) receptors in the dorsal, but not ventral, hippocampus of these lesioned rats suggests that hippocampal 5-ht(2c) receptors vary in their adaptability to changes in serotonergic tone along the dorsoventral axis. 2011-10-14 2022-01-12 Not clear
Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology vol 31 issue 6 2011 20800616 when assessed 7 days after the last mdma injection, levels of hippocampal and striatal serotonin (5ht) were significantly reduced, consistent with published animal studies. 2011-09-29 2022-01-12 Not clear
Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology vol 31 issue 6 2011 20800616 however, the collective pattern of changes in 5ht, ins, glutamate and gaba is consistent with persistent hippocampal neuroadaptations caused by mdma. 2011-09-29 2022-01-12 Not clear
Guadalupe Garc\\xc3\\xada-Alcocer, Angelina Rodr\\xc3\\xadguez, Paulina Moreno-Layseca, Laura C Berumen, Jesica Escobar, Ricardo Miled. Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment. Neuroscience letters vol 486 issue 3 2011 20863873 in this work we studied the changes on the expression of 5-ht(5a) receptors in rat hippocampus induced by leptin, an adipocyte-derived hormone that has been reported to participate in the modulation of food intake and in adult hippocampal neurogenesis. 2011-09-06 2022-01-12 Not clear
Harumasa Takano, Hiroshi Ito, Hidehiko Takahashi, Ryosuke Arakawa, Masaki Okumura, Fumitoshi Kodaka, Tatsui Otsuka, Motoichiro Kato, Tetsuya Suhar. Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [\\xc2\\xb9\\xc2\\xb9C]dasb and [\\xc2\\xb9\\xc2\\xb9C]WAY100635 in young healthy men. Synapse (New York, N.Y.) vol 65 issue 7 2011 21484882 in contrast, the highest binding to 5-ht(1a) receptors was seen in the hippocampal regions, insula, neocortical regions, and dorsal raphe nucleus, and very low binding was found in the thalamus and basal ganglia. 2011-08-16 2022-01-12 Not clear
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