| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
after 12 weeks, we measured the hippocampal and prefrontal cortical brain derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), 5-hydroxytryptamine, dopamine, norepinephrine, malondialdehyde (mda) and reduced glutathione (gsh) levels. |
2021-07-19 |
2023-08-13 |
rat |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
the rats on a diet of whole and refined grains had low bdnf, nt-3, norepinephrine, dopamine and serotonin significantly (p < .01) in both the hippocampus and prefrontal cortex as compared to control rats. |
2021-07-19 |
2023-08-13 |
rat |
| Kate Beecher, Joshua Wang, Angela Jacques, Nicholas Chaaya, Fatemeh Chehrehasa, Arnauld Belmer, Selena E Bartlet. Sucrose Consumption Alters Serotonin/Glutamate Co-localisation Within the Prefrontal Cortex and Hippocampus of Mice. Frontiers in molecular neuroscience. vol 14. 2021-07-16. PMID:34262435. |
although serotonin and glutamate co-localisation has been implicated in reward processing, it is still unknown how chronic sucrose consumption changes this transmission in regions associated with executive control over feeding-such as the prefrontal cortex (pfc) and dentate gyrus (dg) of the hippocampus. |
2021-07-16 |
2023-08-13 |
mouse |
| Barbara Dos Santos, Ariana Ern Schmitz, Gudrian Ricardo Lopes de Almeida, Luiz Felipe de Souza, Jozimar Carlos Szczepanik, Everson Araújo Nunes, Henver Simionato Brunetta, Josiel Mileno Mack, Rui Daniel Prediger, Maurício Peña Cunha, Alcir Luiz Dafr. Fructose Intake Impairs Cortical Antioxidant Defenses Allied to Hyperlocomotion in Middle-Aged C57BL/6 Female Mice. Neurochemical research. vol 45. issue 12. 2021-07-12. PMID:32968860. |
fru intake did not alter serotonin, dopamine, and norepinephrine levels in the hippocampus, prefrontal cortex, and striatum. |
2021-07-12 |
2023-08-13 |
mouse |
| Eman Soliman, Nariman Essmat, Mona F Mahmoud, Amr A A Mahmou. Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 8. 2021-07-06. PMID:32077986. |
antidiabetic agents reduced diabetes-associated depression as indicated by the reduction in the immobility time in the forced swim test, elevation of cortical and hippocampal serotonin and brain-derived neurotrophic factor (bdnf), and the increase in serum β-amyloid 1-42 (aβ1-42) levels. |
2021-07-06 |
2023-08-13 |
rat |
| Eva Florensa-Zanuy, Emilio Garro-Martínez, Albert Adell, Elena Castro, Álvaro Díaz, Ángel Pazos, Karina S Mac-Dowell, David Martín-Hernández, Fuencisla Pilar-Cuélla. Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: Modulation of inflammatory pathways. Biochemical pharmacology. vol 185. 2021-07-01. PMID:33513342. |
the precursor tryptophan (trp), and its metabolites kynurenine (kyn) and serotonin (5-ht) were measured in hippocampus and cortex by hplc. |
2021-07-01 |
2023-08-13 |
mouse |
| Romain Troubat, Pascal Barone, Samuel Leman, Thomas Desmidt, Arnaud Cressant, Boriana Atanasova, Bruno Brizard, Wissam El Hage, Alexandre Surget, Catherine Belzung, Vincent Camu. Neuroinflammation and depression: A review. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:32150310. |
some recent clinical and preclinical evidence suggests that neuroinflammation is a key factor that interacts with the three neurobiological correlates of major depressive disorder: depletion of brain serotonin, dysregulation of the hypothalamus-pituitary-adrenal (hpa) axis and alteration of the continuous production of adult-generated neurons in the dentate gyrus of the hippocampus. |
2021-06-28 |
2023-08-13 |
Not clear |
| Ke Xu, Mingyang Wang, Wei Zhou, Juncai Pu, Haiyang Wang, Peng Xi. Chronic D-ribose and D-mannose overload induce depressive/anxiety-like behavior and spatial memory impairment in mice. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33531473. |
association analysis of the metabolome and transcriptome suggested that the anxiety-like behavior and spatial memory impairment induced by rib and man may be attributed to the changes in four metabolites and 81 genes in the hippocampus, which is involved in amino acid metabolism and serotonin transport. |
2021-06-28 |
2023-08-13 |
mouse |
| Karina Festerling, Karolina Can, Sebastian Kügler, Michael Mülle. Overshooting Subcellular Redox-Responses in Rett-Mouse Hippocampus during Neurotransmitter Stimulation. Cells. vol 9. issue 12. 2021-06-22. PMID:33255426. |
the rogfp redox sensor was expressed in either the cytosol or the mitochondrial matrix of cultured mouse hippocampal neurons, and the responses to transient stimulation by glutamate, serotonin, dopamine and norepinephrine were characterized. |
2021-06-22 |
2023-08-13 |
mouse |
| Heba M Fahmy, Yasser A Khadrawy, Taiseer M Abd-El Daim, Amena S Elfeky, Amera A Abd Rabo, Amira B Mustafa, Islam T Mostaf. Thymoquinone-encapsulated chitosan nanoparticles coated with polysorbate 80 as a novel treatment agent in a reserpine-induced depression animal model. Physiology & behavior. vol 222. 2021-06-21. PMID:32353367. |
in addition, a significant decrease in the monoamine neurotransmitters serotonin (5-ht), norepinephrine (ne) and dopamine (da) was recorded in the cortex, hippocampus and striatum of reserpine-treated rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
d-lys-3-ghrp-6 impairs memory consolidation and downregulates the hippocampal serotonin ht1a, ht7 receptors and glutamate glua1 subunit of ampa receptors. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
we aimed to evaluate the effect of intracerebral injection of a ghrelin receptor antagonist (d-lys-3-ghrp-6) on memory consolidation in the inhibitory avoidance task and on the gene expression levels of serotonin ht1a and ht7 receptors, glutamate glun1 subunit of the nmda and glua1 subunit of the ampa receptors and calcium/calmodulin kinase ii-α in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
meanwhile, it led to a significant downregulation of the mrna expression levels of the hippocampal serotonin ht1a and ht7 receptors and glutamate glua1 subunit of the ampa receptors, but could not affect that of glun1 subunit of the nmda receptors and camkii-α. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
it seems that part of the impairing effect of d-lys-3-ghrp-6 on inhibitory avoidance memory consolidation might be due to a decrease in the expression of serotonin ht1a and ht7 receptors and glutamate ampa receptors in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Peng Wang, Xiaoxia Gao, Fang Zhao, Yao Gao, Kexin Wang, Jun-Sheng Tian, Zhenyu Li, Xue-Mei Qi. Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis. ACS chemical neuroscience. vol 12. issue 12. 2021-06-21. PMID:34060807. |
compared with the control group, the levels of neurotransmitters including 5-hydroxytryptamine (5-ht), acetylcholine, glutamate (glu), and dopamine (da) in the hippocampus and 5-ht, norepinephrine, γ-aminobutyric acid (gaba), and 5-hydroxyindoleacetic acid in serum were significantly changed in the cums rats. |
2021-06-21 |
2023-08-13 |
rat |
| Yong Li, Qian Jiao, Xixun Du, Hong Jian. Sirt1/FoxO1-Associated MAO-A Upregulation Promotes Depressive-Like Behavior in Transgenic Mice Expressing Human A53T α-Synuclein. ACS chemical neuroscience. vol 11. issue 22. 2021-06-18. PMID:33155799. |
we detected reduced levels of na and 5-ht in the hippocampus and na in the locus coeruleus of 6-month a53t mice. |
2021-06-18 |
2023-08-13 |
mouse |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
evaluation of the hippocampal immunoreactivity of the serotonin 5-ht1a, 5-ht2 and 5-ht7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
therefore, to gather more details about the state of the serotoninergic system in the hippocampus under an epileptogenic process, we studied the immunoreactivity of three 5-ht receptors (5-ht1a, 5-ht2 and 5-ht7) as well as the extracellular levels of 5-ht in the hippocampal tissue of epileptic rats with fr. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
a general depletion of the 5-ht and 5-hiia levels in hippocampal tissue from epileptic animals compared with those in controls was observed; in addition, a general decrease in immunoreactivity for the three receptors was found, especially in the dg, which may support the establishment of an excitatory/inhibitory imbalance in the trisynaptic circuit that underlies the fr generation process. |
2021-06-18 |
2023-08-13 |
rat |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
deep brain stimulation of the dorsal raphe abolishes serotonin 1a facilitation of ampa receptor-mediated synaptic currents in the ventral hippocampus. |
2021-06-18 |
2023-08-13 |
rat |