| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mani Surya Kumar Palepu, Siva Nageswara Rao Gajula, Malleshwari K, Rajesh Sonti, Manoj P Dandeka. SCFAs Supplementation Rescues Anxiety- and Depression-like Phenotypes Generated by Fecal Engraftment of Treatment-Resistant Depression Rats. ACS chemical neuroscience. 2024-02-21. PMID:38382546. |
administration of scfas (acetate, propionate, and butyrate at 67.5, 25, and 40 mm, respectively) for 7 days exerted robust antidepressant and antianxiety effects by restoring the levels of scfas in plasma and fecal samples, and proinflammatory cytokines (tnf-α and il-6), serotonin, gaba, norepinephrine, and dopamine in the hippocampus and/or frontal cortex of trd and trd-fmt animals. |
2024-02-21 |
2024-02-24 |
rat |
| Ping Yang, Sheng Huang, Zhihong Luo, Shaoming Zhou, Changjuan Zhang, Yong Zhu, Jingjing Yang, Liang L. Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364739. |
radix bupleuri aqueous extract significantly improved the aberrant behaviors and neuronal damage in scz mice, upregulated syp and psd-95 expression and bdnf levels in hippocampal homogenates, down-regulated da and 5-ht levels, and suppressed microglial activation in scz mice. |
2024-02-16 |
2024-02-19 |
mouse |
| Ping Yang, Sheng Huang, Zhihong Luo, Shaoming Zhou, Changjuan Zhang, Yong Zhu, Jingjing Yang, Liang L. Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364739. |
lactobacillus abundance was decreased in scz mice and reversed by radix bupleuri aqueous extract administration which exhibited a significant negative correlation with il-6, il-1β, da, and 5-ht, and a significant positive correlation with bdnf levels in hippocampal tissues. |
2024-02-16 |
2024-02-19 |
mouse |
| Kavitha Ukkirapandian, Kayalvizhi Elumalai, Karthika Priyadharshini Udaykumar, Sundaravadivel Vp, Muthulakshmi Rangasm. Behavioral and Biochemical Assays for Autism Models of Wistar Rats. Cureus. vol 16. issue 1. 2024-02-13. PMID:38344592. |
the estimation of antioxidant profile (malondialdehyde {mda}, glutathione {gsh}, catalase (cat), and superoxide dismutase {sod}), proinflammatory markers (tumor necrosis factor {tnf} alpha, transforming growth factor {tgf} beta, interleukin {il} 6, and il-1 beta), neurotransmitters (gamma-aminobutyric acid {gaba} and serotonin), and brain-derived neurotrophic factor (bdnf) in the hippocampal region was done. |
2024-02-13 |
2024-02-15 |
rat |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
at the molecular level, we largely replicated the es effects, such as reduced serotonin transporter (sert) expression in the amygdala and increased norepinephrine transporter (net) expression in the medial prefrontal cortex (mpfc) and hippocampus. |
2024-02-09 |
2024-02-12 |
mouse |
| b' Barbora \\xc4\\x8cechov\\xc3\\xa1, Jana Jur\\xc4\\x8dovi\\xc4\\x8dov\\xc3\\xa1, Ivana Petr\\xc3\\xadkov\\xc3\\xa1, \\xc5\\xa0imon Vacul\\xc3\\xadn, \\xc5\\xa0t\\xc4\\x9bp\\xc3\\xa1n \\xc5\\xa0andera, Romana \\xc5\\xa0lamberov\\xc3\\xa. Impact of altered environment and early postnatal methamphetamine exposure on serotonin levels in the rat hippocampus during adolescence. Laboratory animal research. vol 40. issue 1. 2024-02-03. PMID:38308379.' |
impact of altered environment and early postnatal methamphetamine exposure on serotonin levels in the rat hippocampus during adolescence. |
2024-02-03 |
2024-02-05 |
rat |
| b' Barbora \\xc4\\x8cechov\\xc3\\xa1, Jana Jur\\xc4\\x8dovi\\xc4\\x8dov\\xc3\\xa1, Ivana Petr\\xc3\\xadkov\\xc3\\xa1, \\xc5\\xa0imon Vacul\\xc3\\xadn, \\xc5\\xa0t\\xc4\\x9bp\\xc3\\xa1n \\xc5\\xa0andera, Romana \\xc5\\xa0lamberov\\xc3\\xa. Impact of altered environment and early postnatal methamphetamine exposure on serotonin levels in the rat hippocampus during adolescence. Laboratory animal research. vol 40. issue 1. 2024-02-03. PMID:38308379.' |
because developing brain is vulnerable by the action of drugs, or other noxious stimuli, the aim of our study was to examine the effect of early postnatal administration of ma alone or in combination with enriched environment (ee) and/or stress of separate housing, on the levels of serotonin (5ht) in the hippocampus of male rat pups at three stages of adolescence (postnatal day (pnd) 28, 35 and 45). |
2024-02-03 |
2024-02-05 |
rat |
| Hanyu Yang, Linjun You, Zhongyan Wang, Lu Yang, Xun Wang, Wenhan Wu, Hao Zhi, Guangmei Rong, Yun Sheng, Xiaodong Liu, Li Li. Bile duct ligation elevates 5-HT levels in cerebral cortex of rats partly due to impairment of brain UGT1A6 expression and activity via ammonia accumulation. Redox biology. vol 69. 2024-01-01. PMID:38163420. |
using bile duct ligation (bdl) rats as a he model, we verified the elevated 5-ht levels in the cortex but not in the hippocampus and striatum, and found that this cortical 5-ht overload may be caused by bdl-mediated inhibition of udp-glucuronosyltransferase 1a6 (ugt1a6) expression and activity in the cortex. |
2024-01-01 |
2024-01-05 |
rat |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
when l1 (weakest in vitro), l3, and l6 were orally administered in mice with pcm-induced depression, l6 most potently suppressed depression-like behaviors and hippocampal tnf-α and il-6 expression and increased hippocampal serotonin, bdnf, 5ht7, gabaarα1, and gababr1b expression, followed by l3 and l1. |
2023-12-21 |
2023-12-23 |
mouse |
| Alberto Fernández-Teruel, Toni Cañete, Daniel Sampedro-Viana, Ignasi Oliveras, Rafael Torrubia, Adolf Tobeñ. Contribution of the Roman rat lines/strains to personality neuroscience: neurobehavioral modeling of internalizing/externalizing psychopathologies. Personality neuroscience. vol 6. 2023-12-19. PMID:38107777. |
for example, relative to rla rats, rhas exhibit decreased function of the prefrontal cortex (pfc), hippocampus and amygdala, increased functional tone of the mesolimbic dopamine system, a deficit of central metabotropic glutamate-2 (mglu2) receptors, increased density of serotonin 5-ht2a receptors in the pfc, impairment of gabaergic transmission in the pfc, alterations of several synaptic markers and increased density of pyramidal immature dendrític spines in the pfc. |
2023-12-19 |
2023-12-21 |
rat |
| Daniël J van Rensburg, Zander Lindeque, Brian H Harvey, Stephan F Stey. Ndufs4 KO mice: A model to study comorbid mood disorders associated with mitochondrial dysfunction. Pharmacology, biochemistry, and behavior. vol 234. 2023-12-13. PMID:38070656. |
serotonin, kynurenine, and redox status in brain areas relevant to psychiatric pathologies (i.e., prefrontal cortex, hippocampus, and striatum). |
2023-12-13 |
2023-12-17 |
mouse |
| Handan Deng, Yongjun Yu, Qi Sha, Weiyi Sun, Lundan Liang, Feier Ren, Hua Ji, Xiangdi Shen, Xingli Fa. Construction of antibiotic-induced depression mice model and the function of intestinal microbiota. Frontiers in microbiology. vol 14. 2023-12-13. PMID:38088959. |
by using these antibiotics, the concentrations of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and brain-derived neurotrophic factor (bdnf) in mice hippocampus and prefrontal cortex tissues were significantly decreased. |
2023-12-13 |
2023-12-17 |
mouse |
| Dionysis Nikolopoulos, Modestos Nakos-Bimpos, Theodora Manolakou, Alexia Polissidis, Dimitrios T Boumpa. Impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event. Lupus. 2023-12-11. PMID:38073556. |
impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event. |
2023-12-11 |
2023-12-17 |
Not clear |
| José Luis Maldonado-García, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Lenin Pavón, Luvia Sánchez-Torres, Gabriel Gutiérrez-Ospina, Manuel Iván Girón-Pérez, Gabriela Damian-Morales, Jesús Octavio Maldonado-Tapia, Rubén López-Santiago, Martha C Moreno-Lafon. Imipramine Administration in Pharmaceuticals (Basel, Switzerland). vol 16. issue 11. 2023-11-25. PMID:38004391. |
in mouse models, it has been associated with increased levels of il-6, tnf-α, and ifn-γ, a decrease in serotonin and dopamine levels within the hippocampus, induced loss of muscle strength and equilibrium, and increased anxiety and hopelessness. |
2023-11-25 |
2023-11-28 |
mouse |
| Maria Amalia Di Castro, Stefano Garofalo, Alessandro Mormino, Laura Carbonari, Erika Di Pietro, Eleonora De Felice, Myriam Catalano, Laura Maggi, Cristina Limatol. Interleukin-15 alters hippocampal synaptic transmission and impairs episodic memory formation in mice. Brain, behavior, and immunity. vol 115. 2023-11-24. PMID:37992787. |
moreover, we describe that serotonin is involved in mediating the hippocampal effects of il-15, because a selective 5-ht |
2023-11-24 |
2023-11-28 |
mouse |
| Colby E Witt, Sergio Mena, Jordan Holmes, Melinda Hersey, Anna Marie Buchanan, Brenna Parke, Rachel Saylor, Lauren E Honan, Shane N Berger, Sara Lumbreras, Frederik H Nijhout, Michael C Reed, Janet Best, James Fadel, Patrick Schloss, Thorsten Lau, Parastoo Hashem. Serotonin is a common thread linking different classes of antidepressants. Cell chemical biology. 2023-11-22. PMID:37992715. |
we measure hippocampal serotonin in mice with voltammetry and study the effects of acute challenges of escitalopram, fluoxetine, reboxetine, and ketamine. |
2023-11-22 |
2023-11-29 |
mouse |
| Jun Huang, Wentao Jiang, Junping Pan, Xuetao X. Correlation of sLOX-1 and CSF1 with the pathological progression of hypoxic-ischemic encephalopathy in neonatal rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 10. 2023-11-13. PMID:37953571. |
compared with the blank group, slox-1-si and csf1-si groups showed significantly alleviated hippocampal damage, inhibited neuronal apoptosis, reduced 5-ht, da, ne, bax, and cl-caspase-3, and increased bcl-2 (p<0.05). |
2023-11-13 |
2023-11-20 |
rat |
| Mostafa El Mansari, Rami Hamoudeh, Stephen Daniels, Pierre Blie. Wistar Kyoto rats exhibit decreased serotonin neuronal firing and increased norepinephrine burst activity but dampened hippocampal α Journal of psychopharmacology (Oxford, England). 2023-11-09. PMID:37942525. |
wistar kyoto rats exhibit decreased serotonin neuronal firing and increased norepinephrine burst activity but dampened hippocampal α wistar kyoto (wky) rats manifest abnormalities in the function of monoamine receptors and transporters, as well as levels of these neurotransmitters in the brain. |
2023-11-09 |
2023-11-20 |
rat |
| Mostafa El Mansari, Rami Hamoudeh, Stephen Daniels, Pierre Blie. Wistar Kyoto rats exhibit decreased serotonin neuronal firing and increased norepinephrine burst activity but dampened hippocampal α Journal of psychopharmacology (Oxford, England). 2023-11-09. PMID:37942525. |
the present study assessed alterations in the firing activity of serotonin (5-hydroxytryptamine [5-ht]), norepinephrine (ne), and dopamine (da) neurons, as well as the activity of 5-ht and ne receptors and transporters in the hippocampus. |
2023-11-09 |
2023-11-20 |
rat |
| Huijuan Hu, Fan Li, Shaoli Cheng, Tingting Qu, Fanqi Shen, Jie Cheng, Lina Chen, Zhenghang Zhao, Hao H. Alternate-day fasting ameliorated anxiety-like behavior in high-fat diet-induced obese mice. The Journal of nutritional biochemistry. 2023-11-06. PMID:37931668. |
pathological changes in the hippocampus, the expression of sirt1 and its downstream protein monoamine oxidase a (mao-a) in the hippocampus, and the expression of 5-hydroxytryptamine (5-ht) were detected. |
2023-11-06 |
2023-11-08 |
mouse |