| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing Li, He Liu, Licai Zhang, Hongxing Zhang, Fang Zho. The CSF-contacting nucleus regulates learning and memory through synaptic connections with the hippocampus. Neuroscience letters. vol 728. 2021-05-17. PMID:32298724. |
the results showed that learning and memory abilities in animals decreased significantly after the destruction of the csf-contacting nucleus, accompanied by a decrease in 5-ht concentrations in hippocampus. |
2021-05-17 |
2023-08-13 |
Not clear |
| Qing Li, He Liu, Licai Zhang, Hongxing Zhang, Fang Zho. The CSF-contacting nucleus regulates learning and memory through synaptic connections with the hippocampus. Neuroscience letters. vol 728. 2021-05-17. PMID:32298724. |
however, after compensating for 5-ht in the hippocampus continuously, the learning and memory abilities of the animals were significantly improved. |
2021-05-17 |
2023-08-13 |
Not clear |
| Guangjian Li, Jing Yang, Xu Wang, Chen Zhou, Xiangyu Zheng, Weihong Li. Effects of EGCG on depression-related behavior and serotonin concentration in a rat model of chronic unpredictable mild stress. Food & function. vol 11. issue 10. 2021-05-14. PMID:32955535. |
comparison of both cums and cums + egcg groups indicated that egcg administration may decrease the level of serotonin (5-ht) in the colon but increase the level of serotonin (5-ht) in the hippocampus. |
2021-05-14 |
2023-08-13 |
rat |
| Guangjian Li, Jing Yang, Xu Wang, Chen Zhou, Xiangyu Zheng, Weihong Li. Effects of EGCG on depression-related behavior and serotonin concentration in a rat model of chronic unpredictable mild stress. Food & function. vol 11. issue 10. 2021-05-14. PMID:32955535. |
summarily, the investigation results of this experimental study indicated that the intervention of egcg treatment might have considerable implications in several aspects such as anti-depression, regulation of 5-ht concentration, enhancement of intestinal hyper-permeability, and neuroprotection in the hippocampus. |
2021-05-14 |
2023-08-13 |
rat |
| B Coutens, K Rekik, A Harster, P Etienne, V Noirot, B Frances, L Moulédous, B P Guiar. A Citrus Based Sensory Functional Food Ingredient Induces Antidepressant-like Effects: Possible Involvement of an Interplay between the Olfactory and the Serotonergic Systems. Neuroscience. vol 451. 2021-05-14. PMID:33039523. |
serotonin and norepinephrine), it reversed the ability of cort to decrease serotonin neurons firing rate in the dorsal raphe and neuronal maturation in the hippocampus. |
2021-05-14 |
2023-08-13 |
mouse |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
changes that occurred in lh or non-lh rats when compared with those in naïve rats suggest that suppressed da activity in the hippocampus and ofc; elevated da activity in the amygdala; and facilitated 5-ht activity in the hippocampus, mpfc, and nac are phenomena related to the expression of a non-depression-like phenotype. |
2021-05-14 |
2023-08-13 |
rat |
| Yane Costa Chaves, Karina Genaro, Cristina Aparecida Stern, Gisele de Oliveira Guaita, José Alexandre de Souza Crippa, Joice Maria da Cunha, Janaína Menezes Zanovel. Two-weeks treatment with cannabidiol improves biophysical and behavioral deficits associated with experimental type-1 diabetes. Neuroscience letters. vol 729. 2021-05-14. PMID:32360935. |
besides, the levels of serotonin (5-ht), noradrenaline (na) and dopamine (da) in two emotion-related brain regions, the prefrontal cortex (pfc) and hippocampus (hip) were evaluated using high-pressure liquid chromatography. |
2021-05-14 |
2023-08-13 |
rat |
| Yang Li, Tong Liu, Weifeng Lu. Botulinum Neurotoxin Therapy for Depression: Therapeutic Mechanisms and Future Perspective. Frontiers in psychiatry. vol 12. 2021-05-13. PMID:33967844. |
notably, we recently identified that the anti-depressant effects of bont/a associated with up-regulation of 5-ht levels and brain-derived neurotrophic factor (bdnf) expression in the hippocampus in a preclinical mouse model. |
2021-05-13 |
2023-08-13 |
mouse |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
the serotonin levels in the colon, hippocampus, and serum of mice, as well as the human colon carcinoma cells (caco-2), were measured by elisa assays. |
2021-05-10 |
2023-08-13 |
mouse |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
a. muciniphila and its evs may have a biological effect on the induction of serotonin levels in the colon and hippocampus of mice. |
2021-05-10 |
2023-08-13 |
mouse |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
both the bacterium and its evs had significant effects on the mrna expression of genes, involved in serotonin signaling/metabolism in the colon and hippocampus of mice. |
2021-05-10 |
2023-08-13 |
mouse |
| Hang Xu, Xiang Yang Zhang, Wei Wen Wang, Jiesi Wan. Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33953673. |
furthermore, hcq decreased the mrna expression of interleukin-1beta, corticotropin-releasing hormone (crh), a serotonin transporter (slc6a4), and a microglia maker (aif1) in the hippocampus and decreased the mrna expression of brain-derived neurotrophic factor (bdnf) in both the hippocampus and amygdala. |
2021-05-08 |
2023-08-13 |
mouse |
| Madhusmita P Sahu, Yago Pazos-Boubeta, Anna Steinzeig, Katja Kaurinkoski, Michela Palmisano, Olgierd Borowecki, Timo Petteri Piepponen, Eero Castré. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Frontiers in molecular neuroscience. vol 14. 2021-05-04. PMID:33935645. |
consistent with increased 5-ht, the proliferation of hippocampal progenitors is significantly increased, however, long-term survival of newborn cells is unchanged. |
2021-05-04 |
2023-08-13 |
mouse |
| Linlin Zhang, Yongzhao Fan, Xiaoyang Kong, Wu Ha. Neuroprotective effect of different physical exercises on cognition and behavior function by dopamine and 5-HT level in rats of vascular dementia. Behavioural brain research. vol 388. 2021-05-04. PMID:32339549. |
the level in hippocampal dopamine and 5-ht were detected by microdialysis coupled with high performance liquid chromatography. |
2021-05-04 |
2023-08-13 |
rat |
| Linlin Zhang, Yongzhao Fan, Xiaoyang Kong, Wu Ha. Neuroprotective effect of different physical exercises on cognition and behavior function by dopamine and 5-HT level in rats of vascular dementia. Behavioural brain research. vol 388. 2021-05-04. PMID:32339549. |
in addition, hippocampal dopamine and 5-ht level significantly decreased in vd group when compared with c group (p < 0.001); hippocampal dopamine and 5-ht level in ve-vd, ie-vd and te-vd groups were significantly increased when compared with vd group (p < 0.05). |
2021-05-04 |
2023-08-13 |
rat |
| Marta Portero-Tresserra, D Rojic-Becker, C Vega-Carbajal, G Guillazo-Blanch, A Vale-Martínez, M Martí-Nicoloviu. Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33168891. |
noradrenaline (na), dopamine (da), serotonin (5-ht) and its metabolites were measured by high-performance liquid chromatography with electrochemical detection (hplc-ed) in nine brain regions: cerebellum, pons, midbrain, hypothalamus, thalamus, hippocampus, striatum, frontal cortex, and occipital cortex. |
2021-05-03 |
2023-08-13 |
rat |
| Marta Portero-Tresserra, D Rojic-Becker, C Vega-Carbajal, G Guillazo-Blanch, A Vale-Martínez, M Martí-Nicoloviu. Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33168891. |
cr was seen to increase the na levels that are altered by aging in specific brain regions like the striatum, thalamus, cerebellum and hypothalamus, and the da levels in the striatum, as well as modifying the 5-ht levels in the striatum, hypothalamus, pons and hippocampus. |
2021-05-03 |
2023-08-13 |
rat |
| Maria Grazia Morgese, Stefania Schiavone, Maria Bove, Anna Laura Colia, Stefania Dimonte, Paolo Tucci, Luigia Trabac. N-3 PUFA Prevent Oxidative Stress in a Rat Model of Beta-Amyloid-Induced Toxicity. Pharmaceuticals (Basel, Switzerland). vol 14. issue 4. 2021-05-02. PMID:33917814. |
results showed increased hippocampal ros and nox2 levels, serotonin turnover, kynurenine, and noradrenaline contents in aβ-treated rats. |
2021-05-02 |
2023-08-13 |
rat |
| Melkamu Alemu Abame, Yang He, Song Wu, Zhifei Xie, Jian Zhang, Xudong Gong, Chunhui Wu, Jingshan She. Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. Neuroscience letters. vol 744. 2021-04-30. PMID:33388355. |
chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. |
2021-04-30 |
2023-08-13 |
mouse |