| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arina Rawat, Jackey Guo, Thibault Renoir, Terence Y Pang, Anthony J Hanna. Hypersensitivity to sertraline in the absence of hippocampal 5-HT Environmental epigenetics. vol 4. issue 2. 2020-10-01. PMID:30046455. |
hypersensitivity to sertraline in the absence of hippocampal 5-ht the male germ line is capable of transmitting a legacy of stress exposure to the next generation of offspring. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Oleuropein reduces anxiety-like responses by activating of serotonergic and neuropeptide Y (NPY)-ergic systems in a rat model of post-traumatic stress disorder. Animal cells and systems. vol 22. issue 2. 2020-10-01. PMID:30460087. |
ole also blocked the sps-induced decrease in hippocampal serotonin and neuropeptide y expression in hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Jian Liu, Yu-Hong Wang, Wei Li, Lin Liu, Hui Yang, Pan Meng, Yuan-Shan Ha. Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression. Neural regeneration research. vol 14. issue 2. 2020-10-01. PMID:30531012. |
levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line-derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. |
2020-10-01 |
2023-08-13 |
rat |
| Arnauld Belmer, Kate Beecher, Angela Jacques, Omkar L Patkar, Florian Sicherre, Selena E Bartlet. Axonal Non-segregation of the Vesicular Glutamate Transporter VGLUT3 Within Serotonergic Projections in the Mouse Forebrain. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31133811. |
therefore, we combined immunohistochemistry, high resolution confocal imaging, and 3d-reconstruction techniques to map and quantify the distribution of vglut3 immunoreactive boutons within 5-ht vs. sert-positive axons in various regions of the mouse forebrain, including the prefrontal cortex, nucleus accumbens core and shell, bed nucleus of the stria terminalis, dorsal striatum, lateral septum, basolateral and central amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Iva Lukić, Dmitriy Getselter, Omry Koren, Evan Elliot. Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31231198. |
in addition, in mice that were not subjected to atd, gf mice displayed higher levels of tryptophan, serotonin and 5-hydroxyindoleacetic acid (the main degradation product of serotonin) in medial prefrontal cortex (mpfc) and hippocampus (hippo), compared to spf mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Toyoshi Umezu, Taizo Kita, Masatoshi Morit. Hyperactive behavioral phenotypes and an altered brain monoaminergic state in male offspring mice with perinatal hypothyroidism. Toxicology reports. vol 6. 2020-10-01. PMID:31673505. |
significant decreases in dopamine (da) and serotonin turnover were observed in the striatum (st), nucleus accumbens, hypothalamus, and hippocampus in male mice with perinatal hypothyroidism. |
2020-10-01 |
2023-08-13 |
mouse |
| Hirotsugu Azechi, Kōsuke Hakamada, Takanobu Yamamot. A new inbred strain of Fawn-Hooded rats demonstrates mania-like behavioural and monoaminergic abnormalities. IBRO reports. vol 7. 2020-10-01. PMID:31763490. |
serotonin and noradrenaline levels were low in the prefrontal cortex and the hippocampus of fh/hamslc rats, but high serotonin turnover was observed in the prefrontal cortex, hippocampus, and striatum. |
2020-10-01 |
2023-08-13 |
rat |
| Toyoshi Umezu, Taizo Kita, Masatoshi Morit. Dataset on effects of perinatal exposure to propylthiouracil on serum T4, body weight gain, day of eye opening and brain monoamine contents in offspring mice. Data in brief. vol 28. 2020-10-01. PMID:31872013. |
this dataset also describes content of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt), 5-ht, and 5-hydroxyindoleacetic acid (5-hiaa) and their turnover in the hypothalamus, hippocampus, and nucleus accumbens of male offspring mice perinatally exposed to ptu. |
2020-10-01 |
2023-08-13 |
mouse |
| Jenessa N Johnston, Jonathan S Thacker, Charissa Desjardins, Brian D Kulyk, Raquel Romay-Tallon, Lisa E Kalynchuk, Hector J Carunch. Ketamine Rescues Hippocampal Reelin Expression and Synaptic Markers in the Repeated-Corticosterone Chronic Stress Paradigm. Frontiers in pharmacology. vol 11. 2020-10-01. PMID:32982757. |
we also assessed the effects of reelin and ketamine on hippocampal and cerebellar synpatosomes, and on serotonin transporter clustering in peripheral lymphocytes to determine reelin and ketamine's impact at the synaptic and peripheral levels. |
2020-10-01 |
2023-08-13 |
rat |
| Zhiying Hu, Yang Yang, Keqiang Gao, John A Rudd, Marong Fan. Ovarian hormones ameliorate memory impairment, cholinergic deficit, neuronal apoptosis and astrogliosis in a rat model of Alzheimer's disease. Experimental and therapeutic medicine. vol 11. issue 1. 2020-09-30. PMID:26889223. |
in addition, treatment with e2 and p4 was associated with increased expression levels of choline acetyltransferase and 5-hydroxytryptamine receptor 2a (5-ht2a), and decreased expression levels of the glial fibrillary acidic protein in the hippocampus of the rats. |
2020-09-30 |
2023-08-13 |
rat |
| Ping Yang, Liang Li, Xue-Jun Liu, Xiong Cai, Mei-Zhen Sun, Jun-Feng He, Guang Zeng, Hui-Yong Huan. Effect of Chaihu-Shugan-San on the mRNA expression of the 5-HT1A receptor and cellular proliferation in the hippocampus of epileptic rats with depression. Experimental and therapeutic medicine. vol 11. issue 1. 2020-09-30. PMID:26889228. |
the mrna expression levels of the 5-hydroxytryptamine 1a (5-ht1a) receptor and the number of 5-bromo-2'-deoxyuridine (brdu)-labeled cells in the hippocampal dentate gyrus were detected using reverse transcription-quantitative polymerase chain reaction and immunohistochemical analysis, respectively. |
2020-09-30 |
2023-08-13 |
rat |
| Yuan Hu, Yu-Nin Wang, Gang-Qiang Zhang, Xian-Zhe Dong, Wan-Wan Liu, Ping Li. Gan-Dan-Liang-Yi-Tang alleviates p-chlorophenylalanine-induced insomnia through modification of the serotonergic and immune system. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882122. |
gdlyt was also able to alleviate insomnia induced by pcpa in the rodent models, and increased 5-hydroxytryptamine levels in the prefrontal cortex, hippocampus, hypothalamus and corpus striatum of pcpa-treated rats. |
2020-09-30 |
2023-08-13 |
mouse |
| Dasiel O Borroto-Escuela, Caitlin M DuPont, Xiang Li, David Savelli, Davide Lattanzi, Ipsit Srivastava, Manuel Narváez, Michael Di Palma, Elisa Barbieri, Yuniesky Andrade-Talavera, Riccardo Cuppini, Yuji Odagaki, Miklos Palkovits, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:29066953. |
the fgfr1-5-ht1a heteroreceptor complexes are involved in neuroplasticity in the rat hippocampus and in the mesencephalic raphe 5-ht nerve cells. |
2020-09-30 |
2023-08-13 |
rat |
| Flóra Gölöncsér, Mária Baranyi, Diána Balázsfi, Kornél Demeter, József Haller, Tamás F F Freund, Dóra Zelena, Beáta Sperlág. Regulation of Hippocampal 5-HT Release by P2X7 Receptors in Response to Optogenetic Stimulation of Median Raphe Terminals of Mice. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:29075178. |
regulation of hippocampal 5-ht release by p2x7 receptors in response to optogenetic stimulation of median raphe terminals of mice. |
2020-09-30 |
2023-08-13 |
mouse |
| Jung-Wan Cho, Sun-Young Jung, Sang-Won Lee, Sam-Jun Lee, Tae-Beom Seo, Young-Pyo Kim, Dae-Young Ki. Treadmill exercise ameliorates social isolation-induced depression through neuronal generation in rat pups. Journal of exercise rehabilitation. vol 13. issue 6. 2020-09-30. PMID:29326893. |
expression of 5-ht and tph in the dorsal raphe and expression of bdnf and trkb in the hippocampus were decreased by social isolation. |
2020-09-30 |
2023-08-13 |
rat |
| Yong Li, Qian Jiao, Xixun Du, Mingxia Bi, Shuaishuai Han, Lingling Jiao, Hong Jian. Investigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135645. |
although there was no obvious change in the number of 5-htergic neurons in the dorsal raphe nucleus after pcpa treatment, the levels of 5-ht and its metabolite in the frontal cortex and hippocampus were reduced, respectively. |
2020-09-30 |
2023-08-13 |
mouse |
| Yan-Ping Wu, Hua-Ying Gao, Shu-Hua Ouyang, Hiroshi Kurihara, Rong-Rong He, Yi-Fang L. Predator stress-induced depression is associated with inhibition of hippocampal neurogenesis in adult male mice. Neural regeneration research. vol 14. issue 2. 2020-09-30. PMID:30531013. |
the concentrations of hippocampal 5-hydroxytryptamine and 5-hydroxyindoleacetic acid were measured using high-performance liquid chromatography-electrochemical detection. |
2020-09-30 |
2023-08-13 |
mouse |
| Ali A El-Sol. Management of nightmares in patients with posttraumatic stress disorder: current perspectives. Nature and science of sleep. vol 10. 2020-09-30. PMID:30538593. |
although the characteristics of these distressing dreams may vary with the type of traumatic event, the pathophysiology exposes central dysfunction of brain structures at the level of the hippocampus, amygdala, and locus coeruleus, modulated by neurochemical imbalance in nor-adrenergic, dopaminergic, and serotonin pathways. |
2020-09-30 |
2023-08-13 |
human |
| Jonas Waider, Sandy Popp, Boris Mlinar, Alberto Montalbano, Francesco Bonfiglio, Benjamin Aboagye, Elisabeth Thuy, Raphael Kern, Christopher Thiel, Naozumi Araragi, Evgeniy Svirin, Angelika G Schmitt-Böhrer, Renato Corradetti, Christopher A Lowry, Klaus-Peter Lesc. Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31068767. |
serotonin deficiency increases context-dependent fear learning through modulation of hippocampal activity. |
2020-09-30 |
2023-08-13 |
Not clear |
| Michelle M Karth, Brittany J Baugher, Nicole Daly, Melinda D Karth, Stephen C Gironda, Benjamin D Sach. Brain 5-HT Deficiency Prevents Antidepressant-Like Effects of High-Fat-Diet and Blocks High-Fat-Diet-Induced GSK3β Phosphorylation in the Hippocampus. Frontiers in molecular neuroscience. vol 12. 2020-09-30. PMID:31920532. |
brain 5-ht deficiency prevents antidepressant-like effects of high-fat-diet and blocks high-fat-diet-induced gsk3β phosphorylation in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |