| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emilie Puginier, Rahul Bharatiya, Abdeslam Chagraoui, Julien Manem, Yoon H Cho, Maurice Garret, Philippe De Deurwaerdèr. Early neurochemical modifications of monoaminergic systems in the R6/1 mouse model of Huntington's disease. Neurochemistry international. vol 128. 2020-04-24. PMID:31054882. |
the metabolite of 5-ht was also lower in r6/1 mice, mainly in the substantia nigra and hippocampus. |
2020-04-24 |
2023-08-13 |
mouse |
| Kinga Krzysztoforska, Agnieszka Piechal, Kamilla Blecharz-Klin, Justyna Pyrzanowska, Ilona Joniec-Maciejak, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Administration of protocatechuic acid affects memory and restores hippocampal and cortical serotonin turnover in rat model of oral D-galactose-induced memory impairment. Behavioural brain research. vol 368. 2020-04-23. PMID:30978406. |
administration of protocatechuic acid affects memory and restores hippocampal and cortical serotonin turnover in rat model of oral d-galactose-induced memory impairment. |
2020-04-23 |
2023-08-13 |
rat |
| Kinga Krzysztoforska, Agnieszka Piechal, Kamilla Blecharz-Klin, Justyna Pyrzanowska, Ilona Joniec-Maciejak, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Administration of protocatechuic acid affects memory and restores hippocampal and cortical serotonin turnover in rat model of oral D-galactose-induced memory impairment. Behavioural brain research. vol 368. 2020-04-23. PMID:30978406. |
d-gal significantly impaired cognitive performance during the acquisition and recall of mwm compared to control rats and changed concentrations of cortical serotonin as well as its cortical and hippocampal turnover. |
2020-04-23 |
2023-08-13 |
rat |
| Toshiaki Ishii, Ken-Ichi Kinoshita, Yoshikage Muro. Serotonin 5-HT International journal of molecular sciences. vol 20. issue 21. 2020-04-13. PMID:31717815. |
serotonin 5-ht previously, we found that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced parkinson's disease (pd) model mice (pd mice) showed facilitation of hippocampal memory extinction via reduced cyclic adenosine monophosphate (camp)/camp-dependent response element-binding protein (creb) signaling, which may cause cognitive impairment in pd. |
2020-04-13 |
2023-08-13 |
mouse |
| Floriana Volpicelli, L Speranza, S Pulcrano, R De Gregorio, M Crispino, C De Sanctis, M Leopoldo, E Lacivita, U di Porzio, G C Bellenchi, C Perrone-Capan. The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31292861. |
the microrna-29a modulates serotonin 5-ht7 receptor expression and its effects on hippocampal neuronal morphology. |
2020-04-02 |
2023-08-13 |
mouse |
| Floriana Volpicelli, L Speranza, S Pulcrano, R De Gregorio, M Crispino, C De Sanctis, M Leopoldo, E Lacivita, U di Porzio, G C Bellenchi, C Perrone-Capan. The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31292861. |
indeed, it downregulates 5-ht7r gene expression in cultured hippocampal neurons, while the expression of other serotonin receptors is not affected. |
2020-04-02 |
2023-08-13 |
mouse |
| Yun-Ju Huang, Kuan-Hung Lu, Yu-En Lin, Suraphan Panyod, Hsin-Yu Wu, Wan-Ting Chang, Lee-Yan Shee. Garlic essential oil mediates acute and chronic mild stress-induced depression in rats via modulation of monoaminergic neurotransmission and brain-derived neurotrophic factor levels. Food & function. vol 10. issue 12. 2020-04-01. PMID:31735946. |
geo (25 mg per kg bw) effectively decreased the frontal cortex turnover ratio of serotonin (5-ht) and dopamine (da), thus increasing the 5-ht and da levels, with no hippocampal effects. |
2020-04-01 |
2023-08-13 |
rat |
| Peng Chen, Maofang Hei, Lili Kong, Yinyin Liu, Yu Yang, Haibo Mu, Xiuyun Zhang, Shanting Zhao, Jinyou Dua. One water-soluble polysaccharide from Ginkgo biloba leaves with antidepressant activities via modulation of the gut microbiome. Food & function. vol 10. issue 12. 2020-04-01. PMID:31742291. |
consistent with the improvement of depression-like behavior above, gps mice had elevated serotonin and dopamine levels in multiple brain regions including the hippocampus, cerebral cortex and olfactory bulb, relative to unpredictable chronic mild stress (ucms) treatment mice. |
2020-04-01 |
2023-08-13 |
mouse |
| Dariusz Zurawek, Piotr Gruca, Lucyna Antkiewicz-Michaluk, Marta Dziedzicka-Wasylewsk. Resilient Phenotype in Chronic Mild Stress Paradigm Is Associated with Altered Expression Levels of miR-18a-5p and Serotonin 5-HT Molecular neurobiology. vol 56. issue 11. 2020-03-12. PMID:31098953. |
resilient phenotype in chronic mild stress paradigm is associated with altered expression levels of mir-18a-5p and serotonin 5-ht disturbed serotonergic signaling in the hippocampus observed in many individuals vulnerable to stress has been suggested as one of the primary factors contributing to the development of depression. |
2020-03-12 |
2023-08-13 |
human |
| Yael Abreu-Villaça, Vinicius M S Guimarães, André Nunes-Freitas, Ana Carolina Dutra-Tavares, Alex C Manhães, Claudio C Filgueiras, Anderson Ribeiro-Carvalh. Tobacco smoke and ethanol during adolescence: Both combined- and single-drug exposures lead to short- and long-term disruption of the serotonergic system in the mouse brain. Brain research bulletin. vol 146. 2020-03-10. PMID:30584905. |
at pn45 (end-of-exposure), hippocampal serotonin transporter (5 h tt) binding was increased in smk and decreased in etoh male mice. |
2020-03-10 |
2023-08-13 |
mouse |
| Liubov S Kalinichenko, Lara Hammad, Martin Reichel, Zacharias Kohl, Erich Gulbins, Johannes Kornhuber, Christian P Mülle. Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice. Brain research bulletin. vol 146. 2020-03-10. PMID:30716394. |
we found reduced basal extracellular da levels in the nucleus accumbens (nac) and dorsal hippocampus (dh) of tgasm mice with little effect on 5-ht and ne levels. |
2020-03-10 |
2023-08-13 |
mouse |
| Dai Han, Shenxun Shi, Hong Lu. The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia. Journal of integrative neuroscience. vol 18. issue 3. 2020-03-05. PMID:31601072. |
we measured the levels of cognitive impairment using the morris water maze test and protein kinase a activity in hippocampal neurons on presynaptic and postsynaptic serotonin 1a receptors to investigate the effect of dizocilpine-induced cognitive impairment associated with atypical antipsychotic drugs in rats treated by quetiapine alone or combined with way100635/tandospirone. |
2020-03-05 |
2023-08-13 |
human |
| Zian Xia, Chunhu Zhang, Yuanhao Du, Wei Huang, Zhihua Xing, Hui Cao, Kechao Nie, Yang Wang, Xingui Xiong, Bo Yan. The Effect of Traditional Chinese Medicine Zhike-Houpu Herbal Pair on Depressive Behaviors and Hippocampal Serotonin 1A Receptors in Rats After Chronic Unpredictable Mild Stress. Psychosomatic medicine. vol 81. issue 1. 2020-03-02. PMID:30216226. |
the effect of traditional chinese medicine zhike-houpu herbal pair on depressive behaviors and hippocampal serotonin 1a receptors in rats after chronic unpredictable mild stress. |
2020-03-02 |
2023-08-13 |
rat |
| Ankit Uniyal, Raghunath Singh, Ansab Akhtar, Yashika Bansal, Anurag Kuhad, Sangeeta Pilkhwal Sa. Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus. Pharmacology, biochemistry, and behavior. vol 185. 2020-02-26. PMID:31445955. |
neurotransmitters (dopamine and serotonin and their metabolites), bdnf, proinflammatory cytokines (tnf-α, il-6), caspase-3, and markers for oxidative stress were assessed in the hippocampus and cortex while corticosterone and nitrite levels were estimated in plasma. |
2020-02-26 |
2023-08-13 |
rat |
| Daehyuk Jang, Hyun-Ju Lee, Kyungjun Lee, Kyu-Ri Kim, Ran Won, Seung Eun Lee, Insop Shi. White Ginseng Ameliorates Depressive Behavior and Increases Hippocampal 5-HT Level in the Stressed Ovariectomized Rats. BioMed research international. vol 2019. 2020-02-26. PMID:31612144. |
white ginseng ameliorates depressive behavior and increases hippocampal 5-ht level in the stressed ovariectomized rats. |
2020-02-26 |
2023-08-13 |
rat |
| Sophia French, Carter Wra. Serotonin Syndrome and Hippocampal Infarction. Pediatric neurology. vol 90. 2020-02-25. PMID:30420109. |
serotonin syndrome and hippocampal infarction. |
2020-02-25 |
2023-08-13 |
Not clear |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. Correction: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 14. issue 1. 2020-02-25. PMID:30682166. |
correction: t-type calcium channel enhancer sak3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. |
2020-02-25 |
2023-08-13 |
mouse |
| Yang Li, Jing Liu, Xu Liu, Cun-Jin Su, Qi-Lin Zhang, Zhi-Hong Wang, Lei-Fang Cao, Xue-Yan Guo, Ya Huang, Weifeng Luo, Tong Li. Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. Neuroscience bulletin. vol 35. issue 4. 2020-02-18. PMID:30900142. |
bont/a significantly increased the 5-hydroxytryptamine (5-ht) levels in several brain regions, including the hippocampus and hypothalamus, in srs mice. |
2020-02-18 |
2023-08-13 |
mouse |
| Yang Li, Jing Liu, Xu Liu, Cun-Jin Su, Qi-Lin Zhang, Zhi-Hong Wang, Lei-Fang Cao, Xue-Yan Guo, Ya Huang, Weifeng Luo, Tong Li. Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. Neuroscience bulletin. vol 35. issue 4. 2020-02-18. PMID:30900142. |
collectively, these results demonstrated that bont/a treatment has anti-depressant-like activity in mice, and this is associated with increased 5-ht levels and the activation of bdnf/erk/creb pathways in the hippocampus, supporting further investigation of bont/a therapy in depression. |
2020-02-18 |
2023-08-13 |
mouse |
| Atef Tadros Fahim, Amal Ahmed Abd El-Fattah, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate testicular dysfunction caused by chronic unpredictable mild stress-induced depression in rats. Archives of biochemistry and biophysics. vol 665. 2020-02-14. PMID:30904419. |
cums-induced depressive-like behaviours in rats were evidenced by increased serum corticosterone levels and decreased serum and hippocampal serotonin levels as well as decreased hippocampal bdnf levels. |
2020-02-14 |
2023-08-13 |
rat |