| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas J Pucadyil, Amitabha Chattopadhya. Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus. Biochimica et biophysica acta vol 1663 issue 1-2 2004 15157621 |
we have examined the modulatory role of cholesterol on the ligand binding activity and g-protein coupling of the bovine hippocampal 5-ht(1a) receptor by depleting cholesterol from native membranes using methyl-beta-cyclodextrin (mbetacd). |
2004-07-22 |
2022-01-12 |
Not clear |
| Thomas J Pucadyil, Amitabha Chattopadhya. Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus. Biochimica et biophysica acta vol 1663 issue 1-2 2004 15157621 |
removal of cholesterol from bovine hippocampal membranes using varying concentrations of mbetacd results in a concentration-dependent reduction in specific binding of the agonist 8-oh-dpat to 5-ht(1a) receptors. |
2004-07-22 |
2022-01-12 |
Not clear |
| Els van Riel, Neeltje G van Gemert, Onno C Meijer, Marian Jo\\xc3\\xabl. Effect of early life stress on serotonin responses in the hippocampus of young adult rats. Synapse (New York, N.Y.) vol 53 issue 1 2004 15150736 |
we conclude that maternal deprivation can alter specific aspects of hippocampal 5-ht transmission later on in life, possibly by post-translational modification of the 5-ht1a-receptor or changes in the 5-ht1a-receptor signal transduction pathway. |
2004-07-16 |
2022-01-12 |
Not clear |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry vol 89 issue 4 2004 15140183 |
anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by d and 5-ht receptors. |
2004-06-04 |
2022-01-12 |
Not clear |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry vol 89 issue 4 2004 15140183 |
the present microdialysis study evaluated the anticonvulsant activity of extracellular hippocampal dopamine (da) and serotonin (5-ht) with concomitant assessment of the possible mutual interactions between these monoamines. |
2004-06-04 |
2022-01-12 |
Not clear |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry vol 89 issue 4 2004 15140183 |
our results suggest that, within a certain concentration range, da and 5-ht contribute independently to the prevention of hippocampal epileptogenesis via, respectively, d(2) and 5-ht(1a) receptor activation. |
2004-06-04 |
2022-01-12 |
Not clear |
| Eleanor J Bull, Peter H Hutson, Kevin C F Fon. Decreased social behaviour following 3,4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity. Neuropharmacology vol 46 issue 2 2004 14680758 |
on pnd 92, hippocampal, frontal cortical and striatal 5-hydroxytryptamine (5-ht) was significantly reduced in mdma pre-treated rats by between 16% and 22%, without any accompanying change in [(3)h]paroxetine binding in cortical homogenates. |
2004-05-28 |
2022-01-14 |
Not clear |
| Philip Heiser, Eva Schulte, Christiane Hausmann, Ralf Becker, Helmut Remschmidt, J\\xc3\\xbcrgen-Christian Krieg, Helmut Vedde. Effects of clozapine and its metabolites on the 5-HT2 receptor system in cortical and hippocampal cells in vitro. Progress in neuro-psychopharmacology & biological psychiatry vol 28 issue 2 2004 14751426 |
the goal of the present study was to determine the effects of clozapine (cloz) and its metabolites norclozapine (norcloz) and clozapine-n-oxide (cloz-n-oxide) on the 5-ht(2) receptor system on the levels of protein and gene expression in in vitro systems of primary cortical cells of the rat and human hippocampal shs5y5 neuroblastoma cells. |
2004-05-28 |
2022-01-12 |
Not clear |
| Takashi Yoshitake, Jan Keh. Differential effects of (R)-, (R, S)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on hippocampal serotonin release and induction of hypothermia in awake rats. Life sciences vol 74 issue 23 2004 15050424 |
the reduction of hippocampal 5-ht levels induced by subcutaneous (s.c.) administration of (r,s)-8-oh-dpat (0.3 mg/kg) was significantly attenuated by the presence of 5-ht reuptake inhibitor citalopram in ringer solution only at its peak value at 40 min (maximal reduction to 60% compared to 46% of control values in ringer-perfused rats), whereas the overall effects were comparable at both experimental conditions. |
2004-04-20 |
2022-01-12 |
Not clear |
| Takashi Yoshitake, Jan Keh. Differential effects of (R)-, (R, S)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on hippocampal serotonin release and induction of hypothermia in awake rats. Life sciences vol 74 issue 23 2004 15050424 |
it is concluded that the acute systemic dose of (r)-, (s)- and (r,s)-8-oh-dpat enantiomers exerted enantiomer-specific effects on 5-ht(1a) receptor-mediated function both at the presynaptic and postsynaptic sites as revealed by monitoring hippocampal 5-ht levels and body temperature. |
2004-04-20 |
2022-01-12 |
Not clear |
| Amani E Khalif. Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. Pharmacology, biochemistry, and behavior vol 75 issue 4 2004 12957216 |
on the other hand, the lower dose of zuclopenthixol elevated cortical norepinephrine (ne) level, while the higher dose elevated both cortical and hippocampal ne level together with hippocampal serotonin (5-ht) level. |
2004-04-13 |
2022-01-11 |
Not clear |
| L Manuel-Apolinar, A Menese. 8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production. Behavioural brain research vol 148 issue 1-2 2004 14684258 |
thus, cortical and hippocampal increased on camp production was observed following administration of the 5-ht(1a/7) agonist 8-oh-dpat. |
2004-03-01 |
2022-01-14 |
Not clear |
| Takashi Yoshitake, Fu-Hua Wang, Eugenia Kuteeva, Kristina Holmberg, Masatoshi Yamaguchi, Jacqueline N Crawley, Robert Steiner, Tamas Bartfai, Sven Ove Ogren, Tomas H\\xc3\\xb6kfelt, Jan Keh. Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Proceedings of the National Academy of Sciences of the United States of America vol 101 issue 1 2004 14701907 |
these results suggest that the na and 5-ht hippocampal afferents in galoe/p mice are hypersensitive to both conditioned and unconditioned stressful stimuli, such as fs, and that this effect is mediated by galanin receptors. |
2004-02-25 |
2022-01-13 |
Not clear |
| Krzysztof Tokarski, Agnieszka Zahorodna, Bartosz Bobula, Grzegorz Hes. 5-HT7 receptors increase the excitability of rat hippocampal CA1 pyramidal neurons. Brain research vol 993 issue 1-2 2004 14642852 |
in the ca1 area of rat hippocampal slices, a combined application of 5-ct, a potent 5-ht(1a) and 5-ht(7) receptor agonist, and way 100635, a selective 5-ht(1a) receptor antagonist, resulted in a reversible increase of the ca1 extracellular population spike amplitude. |
2004-02-12 |
2022-01-13 |
Not clear |
| Akihiko Oshima, Cornelia Flachskamm, Johannes M H M Reul, Florian Holsboer, Astrid C E Linthors. Altered serotonergic neurotransmission but normal hypothalamic-pituitary-adrenocortical axis activity in mice chronically treated with the corticotropin-releasing hormone receptor type 1 antagonist NBI 30775. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 28 issue 12 2004 12915860 |
owing to the intricate relationship between crh and serotonin (5-ht), we studied the effects of chronic oral treatment of c57bl6/n mice with the crh-r1 antagonist nbi 30775 (formerly known as r121919) on hippocampal serotonergic neurotransmission during basal (on 15th day of treatment) and stress (forced swimming; on 16th day of treatment) conditions by in vivo microdialysis. |
2004-02-10 |
2022-01-11 |
Not clear |
| H Waage-Baudet, J M Lauder, D B Dehart, K Kluckman, S Hiller, G S Tint, K K Suli. Abnormal serotonergic development in a mouse model for the Smith-Lemli-Opitz syndrome: implications for autism. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol 21 issue 8 2004 14659996 |
using a targeting strategy designed to virtually eliminate dhcr7 activity, we have created a slos mouse model that exhibits commissural deficiencies, hippocampal abnormalities, and hypermorphic development of serotonin (5-ht) neurons. |
2004-02-09 |
2022-01-13 |
Not clear |
| Beth A Luellen, Diane B Miller, Angela C Chisnell, Dennis L Murphy, James P O'Callaghan, Anne Milasincic Andrew. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of pharmacology and experimental therapeutics vol 307 issue 3 2004 14561848 |
in the present investigation into the acute effects of 2'-nh2-mptp in mice, profound decreases in cortical and hippocampal 5-ht and ne to 10 to 40% of control were observed as early as 30 min post-treatment and lasted throughout the ensuing 21 days. |
2004-01-29 |
2022-01-12 |
Not clear |
| Stanley L Lin, Nadine N Johnson-Farley, David R Lubinsky, Daniel S Cowe. Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac. Journal of neurochemistry vol 87 issue 5 2003 14622088 |
the roles of 3',5'-cyclic adenosine monophosphate (camp) and protein kinase a in 5-hydroxytryptamine (5-ht)7 receptor-mediated activation of extracellular-regulated kinase (erk) were studied in cultured hippocampal neurons and transfected pc12 cells. |
2003-12-18 |
2022-01-12 |
Not clear |
| Boris Mlinar, Renato Corradett. Endogenous 5-HT, released by MDMA through serotonin transporter- and secretory vesicle-dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5-HT1B receptors located on CA1 pyramidal neurons. The European journal of neuroscience vol 18 issue 6 2003 14511335 |
endogenous 5-ht, released by mdma through serotonin transporter- and secretory vesicle-dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5-ht1b receptors located on ca1 pyramidal neurons. |
2003-12-05 |
2022-01-12 |
Not clear |
| E van Riel, O C Meijer, P J Steenbergen, M Jo\\xc3\\xabl. Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons. Neuroscience vol 120 issue 3 2003 12895506 |
in the present study, serotonin (5-ht) responses of hippocampal pyramidal cornu ammonis 1 (ca1) neurons were studied in rats subjected twice daily for 21 days to unpredictable stressors. |
2003-12-04 |
2022-01-11 |
Not clear |