| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laila Abdel-Hafiz, Andreas Müller-Schiffmann, Carsten Korth, Benedetta Fazari, Owen Y Chao, Susanne Nikolaus, Sandra Schäble, Arne Herring, Kathy Keyvani, Valéria Lamounier-Zepter, Joseph P Huston, Maria A de Souza Silv. Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease. Neurobiology of aging. vol 69. 2019-05-21. PMID:29803148. |
in 7- and 12-month-old mice, levels of acetylcholine, dopamine, and serotonin were measured in neostriatum, ventral striatum, prefrontal cortex, hippocampus, amygdala, and entorhinal cortex by high-performance liquid chromatography. |
2019-05-21 |
2023-08-13 |
mouse |
| Laila Abdel-Hafiz, Andreas Müller-Schiffmann, Carsten Korth, Benedetta Fazari, Owen Y Chao, Susanne Nikolaus, Sandra Schäble, Arne Herring, Kathy Keyvani, Valéria Lamounier-Zepter, Joseph P Huston, Maria A de Souza Silv. Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease. Neurobiology of aging. vol 69. 2019-05-21. PMID:29803148. |
the tgdimer mice had lower serotonin turnover rates in hippocampus, ventral striatum, and amygdala relative to wild type controls. |
2019-05-21 |
2023-08-13 |
mouse |
| Manjun Shen, Yi Yang, Ying Wu, Beibei Zhang, Haishan Wu, Lu Wang, Hui Tang, Jindong Che. L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions. Phytotherapy research : PTR. vol 33. issue 2. 2019-05-21. PMID:30474152. |
the monoamine neurotransmitters that involve serotonin (5-ht), norepinephrine (ne), and dopamine (da) were measured in the limbic-cortical-striatal-pallidal-thalamic (lcspt)-circuit related brain regions, including the prefrontal cortex (pfc), nucleus accumbens (nac), striatum (st), amygdala, and hippocampus (hip). |
2019-05-21 |
2023-08-13 |
rat |
| Tsutomu Wada, Azusa Sameshima, Rika Yonezawa, Mayuko Morita, Kanae Sawakawa, Hiroshi Tsuneki, Toshiyasu Sasaoka, Shigeru Sait. Impact of central and peripheral estrogen treatment on anxiety and depression phenotypes in a mouse model of postmenopausal obesity. PloS one. vol 13. issue 12. 2019-05-20. PMID:30589890. |
hippocampal expression of glucocorticoid receptor mrna and serotonin 1a receptor mrna was significantly increased in ovx-hf mice and was decreased in e2-treated mice. |
2019-05-20 |
2023-08-13 |
mouse |
| I V Karpova, V V Mikheev, V V Marysheva, N A Kuritcyna, E R Bychkov, P D Shabano. [Central monoaminergic systems sensitivity to acute hypoxia with hypercapnia changes after the maintenance under the long-term social isolation]. Biomeditsinskaia khimiia. vol 64. issue 6. 2019-05-13. PMID:30632979. |
the levels of dopamine (da), serotonin (5-ht) and their metabolites - dioxyphenylacetic (dopac), homovanillic (hva), and 5-hydroxyindoleacetic (5-hiaa) acids - were determined by hplc in the cerebral cortex, hippocampus and striatum of the right and left sides of the brain. |
2019-05-13 |
2023-08-13 |
mouse |
| Jing Du, Rodrigo Machado-Vieira, Rushaniya Khairov. Synaptic plasticity in the pathophysiology and treatment of bipolar disorder. Current topics in behavioral neurosciences. vol 5. 2019-05-07. PMID:25236555. |
we conclude that increased serotonin, norepinephrine, dopamine, brain-derived neurotrophic factor (bdnf), acute corticosterone, and antidepressant treatments lead to enhanced synaptic strength in the hippocampus and also correlate with antidepressant-like behaviors. |
2019-05-07 |
2023-08-13 |
Not clear |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
t-type calcium channel enhancer sak3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. |
2019-04-29 |
2023-08-13 |
mouse |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
the t-type calcium channel-specific inhibitor, nnc 55-0396 (1 μm) significantly antagonized sak3-enhanced da and 5-ht releases in the hippocampus. |
2019-04-29 |
2023-08-13 |
mouse |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
moreover, hippocampal da and 5-ht contents were significantly decreased in appnl-gf ki mice. |
2019-04-29 |
2023-08-13 |
mouse |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
taken together, our data suggest that sak3 promotes monoamine da and 5-ht releases by enhancing the t-type calcium channel and nachr in the mouse hippocampus. |
2019-04-29 |
2023-08-13 |
mouse |
| Frances Xin, Erin Fischer, Christopher Krapp, Elizabeth N Krizman, Yemin Lan, Clementina Mesaros, Nathaniel W Snyder, Amita Bansal, Michael B Robinson, Rebecca A Simmons, Marisa S Bartolome. Mice exposed to bisphenol A exhibit depressive-like behavior with neurotransmitter and neuroactive steroid dysfunction. Hormones and behavior. vol 102. 2019-04-25. PMID:29763587. |
high performance liquid chromatography demonstrated a male-specific reduction in hippocampal serotonin. |
2019-04-25 |
2023-08-13 |
mouse |
| Karen K Y Lee, Chloe N Soutar, Hans C Dringenber. Gating of long-term potentiation (LTP) in the thalamocortical auditory system of rats by serotonergic (5-HT) receptors. Brain research. vol 1683. 2019-04-19. PMID:29325855. |
the neuromodulator serotonin (5-hydroxytryptamine, 5-ht) plays an important role in controlling the induction threshold and maintenance of long-term potentiation (ltp) in the visual cortex and hippocampus of rodents. |
2019-04-19 |
2023-08-13 |
rat |
| Haitham S Mohammed, Yasser A Khadrawy, Tharwat M El-Sherbini, Hanaa M Ame. Electrocortical and Biochemical Evaluation of Antidepressant Efficacy of Formulated Nanocurcumin. Applied biochemistry and biotechnology. vol 187. issue 3. 2019-04-17. PMID:30167967. |
the chronic administration of reserpine resulted in a significant decrease in the duration of the active phase in the fst; a significant decrease in the cortical and hippocampal levels of serotonin, norepinephrine, and dopamine; a significant increase in spectral power of alpha and delta waves; and a significant decrease in spectral power of theta, beta-1, and beta-2 waves with respect to control values. |
2019-04-17 |
2023-08-13 |
rat |
| Haitham S Mohammed, Yasser A Khadrawy, Tharwat M El-Sherbini, Hanaa M Ame. Electrocortical and Biochemical Evaluation of Antidepressant Efficacy of Formulated Nanocurcumin. Applied biochemistry and biotechnology. vol 187. issue 3. 2019-04-17. PMID:30167967. |
additionally, the levels of serotonin and dopamine have been restored; however, the level of norepinephrine has been not completely recovered in both cortex and hippocampus. |
2019-04-17 |
2023-08-13 |
rat |
| Yong-Ku Kim, Meysam Amidfar, Eunsoo Wo. A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in post-traumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 91. 2019-04-15. PMID:29932946. |
such heightened activity of the immune system may cause alterations in the structure and function of brain regions-for example, the amygdala, hippocampus, medial prefrontal cortex, anterior cingulate cortex, and insula-through changes in levels of serotonin and kynurenine pathway metabolites, and direct neurotoxic effects of cytokines. |
2019-04-15 |
2023-08-13 |
Not clear |
| Hanjie Yu, Dan Lv, Mengxin Shen, Yanhua Zhang, Dongsheng Zhou, Zhongming Chen, Chuang Wan. BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1. Psychiatry research. vol 271. 2019-04-15. PMID:30529315. |
in addition, the reserpine-induced decreases in serotonin transporter (5-htt), brain-derived neurotrophic factor (bdnf) and tryptophan hydroxylase 1 (tph1) in mouse hippocampus and prefrontal cortex (pfc) were significantly reversed by scopolamine. |
2019-04-15 |
2023-08-13 |
mouse |
| Zhi-Kun Qiu, Guan-Hua Zhang, De-Sheng Zhong, Jia-Li He, Xu Liu, Ji-Sheng Chen, Da-Nian We. Puerarin ameliorated the behavioral deficits induced by chronic stress in rats. Scientific reports. vol 7. issue 1. 2019-04-10. PMID:28740098. |
in addition, enzyme linked immunosorbent assay (elisa) and high performance liquid chromatography-electrochemical detection (hplc-ecd) showed that chronic treatment of puerarin (60 and 120 mg/kg, i.g) reversed the decreased levels of progesterone, allopregnanolone, serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in prefrontal cortex and hippocampus of post-cus rats. |
2019-04-10 |
2023-08-13 |
rat |
| Yuanyuan Liu, Zhongying Liu, Mengying Wei, Mingxin Hu, Kexin Yue, Rongbing Bi, Shan Zhai, Zifeng Pi, Fengrui Song, Zhiqiang Li. Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's disease. Food & function. vol 10. issue 1. 2019-04-09. PMID:30623955. |
in the hippocampus of the model rats, the contents of γ-aminobutyric acid, acetylcholine, glycine, norepinephrine, taurine, serotonin and dopamine were significantly decreased and the contents of glutamate and aspartic acid were increased significantly. |
2019-04-09 |
2023-08-13 |
rat |
| M Kondo, Y Koyama, Y Nakamura, S Shimad. A novel 5HT3 receptor-IGF1 mechanism distinct from SSRI-induced antidepressant effects. Molecular psychiatry. vol 23. issue 4. 2019-04-04. PMID:28439104. |
in this study, we show that a serotonin type 3 receptor (5ht3r) agonist induces antidepressant effects as well as hippocampal neurogenesis independent of fluoxetine (a commonly used ssri). |
2019-04-04 |
2023-08-13 |
Not clear |
| Aya Abdalla, Christopher W Atcherley, Pavithra Pathirathna, Srimal Samaranayake, Beidi Qiang, Edsel Peña, Stephen L Morgan, Michael L Heien, Parastoo Hashem. In Vivo Ambient Serotonin Measurements at Carbon-Fiber Microelectrodes. Analytical chemistry. vol 89. issue 18. 2019-04-01. PMID:28795565. |
in vivo, we report basal serotonin levels in the ca2 region of the hippocampus as 64.9 ± 2.3 nm (n = 15 mice, weighted average ± standard error). |
2019-04-01 |
2023-08-13 |
mouse |