| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P S Rojas, F Aguayo, D Neira, M Tejos, E Aliaga, J P Muñoz, C S Parra, J L Fiedle. Dual effect of serotonin on the dendritic growth of cultured hippocampal neurons: Involvement of 5-HT Molecular and cellular neurosciences. vol 85. 2018-07-25. PMID:28974382. |
dual effect of serotonin on the dendritic growth of cultured hippocampal neurons: involvement of 5-ht serotonin acts through its receptors (5-htrs) to shape brain networks during development and modulates essential functions in mature brain. |
2018-07-25 |
2023-08-13 |
Not clear |
| Sha Liao, Jinpeng Lv, Jia Zhou, Praveen Kumar Kalavagunta, Jing Shan. Effects of two chronic stresses on mental state and hair follicle melanogenesis in mice. Experimental dermatology. vol 26. issue 11. 2018-07-20. PMID:28480983. |
we found that stress changed hippocampal morphology, decreased 5-ht level in brain and skin and down-regulated 5-ht1a receptor expression in hippocampal ca1 region and skin. |
2018-07-20 |
2023-08-13 |
mouse |
| N Kokras, N Pastromas, D Papasava, C de Bournonville, C A Cornil, C Dall. Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats. Psychoneuroendocrinology. vol 87. 2018-07-13. PMID:29054014. |
the hippocampus and prefrontal cortex (pfc) were analyzed for monoamine (noradrenaline, dopamine and serotonin), as well as amino acid (gaba, glutamate, glycine, taurine, alanine and histidine) levels. |
2018-07-13 |
2023-08-13 |
human |
| Darcy Litteljohn, Chris Rudyk, Zach Dwyer, Kyle Farmer, Teresa Fortin, Shawn Hayle. The impact of murine LRRK2 G2019S transgene overexpression on acute responses to inflammatory challenge. Brain, behavior, and immunity. vol 67. 2018-07-11. PMID:28893563. |
indeed, g2019s mice had altered basal levels and turnover of dopamine within the striatum, along with changes in hippocampal serotonin and norepinephrine activity in response to lps and ifn-γ. |
2018-07-11 |
2023-08-13 |
mouse |
| Nasrin Hashemi-Firouzi, Alireza Komaki, Sara Soleimani Asl, Siamak Shahid. The effects of the 5-HT7 receptor on hippocampal long-term potentiation and apoptosis in a rat model of Alzheimer's disease. Brain research bulletin. vol 135. 2018-07-05. PMID:28987281. |
long-term potentiation (ltp) of synaptic function is a model of learning- and memory-related neural plasticity, of which serotonin (5-ht) is a key modulator in the hippocampus. |
2018-07-05 |
2023-08-13 |
rat |
| Jaya Thomas, Razia Khanam, Divya Vohor. Activation of indoleamine 2, 3- dioxygenase pathway by olanzapine augments antidepressant effects of venlafaxine in mice. Psychiatry research. vol 258. 2018-07-03. PMID:28911850. |
swiss albino mice were subjected to chronic forced-swim stress and evaluation for antidepressant-like activity was performed on 7th, 14th and 21st day following which serum levels of pro-inflammatory cytokines (il-1β and il-6 levels) and the levels of hippocampal kynurenine (kyn), tryptophan (trp) and serotonin (5ht) were estimated. |
2018-07-03 |
2023-08-13 |
mouse |
| Yuan Liu, Dexiang Liu, Jingjing Xu, Hong Jiang, Fang Pa. Early adolescent stress-induced changes in prefrontal cortex miRNA-135a and hippocampal miRNA-16 in male rats. Developmental psychobiology. vol 59. issue 8. 2018-07-02. PMID:28944448. |
mirna-135a in the prefrontal cortex (pfc) and mirna-16 in the hippocampus (hip) are closely related to the 5-ht neurotransmitter system. |
2018-07-02 |
2023-08-13 |
rat |
| Xi Jiang, Qizhi Yan, Fuhe Liu, Changfeng Jing, Lianshu Ding, Lijin Zhang, Cong Pan. Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain. Neuroscience letters. vol 662. 2018-07-02. PMID:28982597. |
subsequent study indicated that indoleamine 2,3-dioxygenase (ido) expression increased after cci surgery in hippocampus and spinal cord, accompanied by increase of kynurenine (kyn)/tryptophan (try) ratio, decrease of serotonin (5-ht)/try ratio and decrease of 5-ht/5-hiaa ratio. |
2018-07-02 |
2023-08-13 |
mouse |
| Cheng Xue Du, Jian Liu, Yuan Guo, Li Zhang, Qiao Jun Zhan. Lesions of the lateral habenula improve working memory performance in hemiparkinsonian rats. Neuroscience letters. vol 662. 2018-06-29. PMID:29054431. |
neurochemical results found that lesions of the lhb increased da levels in the mpfc, hippocampus and amygdala in the mfb and lhb lesion group, as well as serotonin (5-ht) level in the mpfc. |
2018-06-29 |
2023-08-13 |
rat |
| Cheng Xue Du, Jian Liu, Yuan Guo, Li Zhang, Qiao Jun Zhan. Lesions of the lateral habenula improve working memory performance in hemiparkinsonian rats. Neuroscience letters. vol 662. 2018-06-29. PMID:29054431. |
these findings suggest that da depletion plays a key role in working memory impairment, and lesions of the lhb improve working memory in the mfb-lesioned rats, which involves in increases in the levels of da and 5-ht in the mpfc, hippocampus and amygdala. |
2018-06-29 |
2023-08-13 |
rat |
| Wan-Hui Lin, Xiao-Feng Li, Ming-Xing Lin, Ying Zhou, Hua-Pin Huan. Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats. Molecular medicine reports. vol 16. issue 6. 2018-06-26. PMID:28983622. |
the aim of the present study was to investigate the role of paroxetine intervention in epilepsy, and its association with the expression of serotonin transporter (sert) and hippocampal apoptosis. |
2018-06-26 |
2023-08-13 |
rat |
| Victor Mathis, Lucas Lecourtie. Role of the lateral habenula in memory through online processing of information. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28709783. |
animal research has recently attracted attention on the lateral habenula which, as shown in rodents and non-human primates, seems to process information stemming in the main regions involved in memory processing, e.g., the medial prefrontal cortex, the hippocampus, the amygdala, the septal region, the basal ganglia, and participates in the control of key memory-related neurotransmitters systems, i.e., dopamine, serotonin, acetylcholine. |
2018-06-18 |
2023-08-13 |
Not clear |
| Pei Liu, Vincent Grenier, Wootack Hong, Vikram R Muller, Evan W Mille. Fluorogenic Targeting of Voltage-Sensitive Dyes to Neurons. Journal of the American Chemical Society. vol 139. issue 48. 2018-06-18. PMID:29154543. |
by targeting ple to neurons, vf-ex2 can interrogate the neuromodulatory effects of serotonin in cultured hippocampal neurons. |
2018-06-18 |
2023-08-13 |
Not clear |
| I V Karpova, E R Bychkov, V V Marysheva, V V Mikheev, P D Shabano. Effects of Oxytocin on the Levels and Metabolism of Monoamines in the Brain of White Outbred Mice during Long-Term Social Isolation. Bulletin of experimental biology and medicine. vol 163. issue 6. 2018-06-13. PMID:29063330. |
disappearance of initial right-sided asymmetry in the content of dopamine metabolites in the striatum, increased 5-hydroxyacetic acid content in the right striatum, and disappearance of the initial left-sided asymmetry in serotonin level in the cortex were noted; we also found a decrease in norepinephrine content in the left hippocampus with appearance of asymmetry and higher content in the right olfactory tubercle. |
2018-06-13 |
2023-08-13 |
mouse |
| Cindy S Tao, Prateek Dhamija, Linda Booij, Janet L Menar. Adversity in early adolescence promotes an enduring anxious phenotype and increases serotonergic innervation of the infralimbic medial prefrontal cortex. Neuroscience. vol 364. 2018-06-08. PMID:28893650. |
after behavioural testing, we used immunohistochemistry for the 5-ht transporter (sert) to evaluate 5-ht innervation profiles in the medial prefrontal cortex (mpfc) and ventral hippocampus (vh). |
2018-06-08 |
2023-08-13 |
rat |
| Christine Winter, Dana M Greene, Paraskevi Mavrogiorgou, Helge Schaper, Reinhard Sohr, Abel Bult-Ito, Georg Jucke. Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive-compulsive disorder. Behavioural brain research. vol 337. 2018-06-08. PMID:28916503. |
the neurochemical investigation of several brain regions of the corticostriato-thalamocortical circuity, i.e., nucleus caudatus (cpu), nucleus accumbens (nac), globus pallidus (gp), hippocampus (hpc), amygdala (am), ventral tegmental area (vta) and substantia nigra (sn) was performed by electrochemical (serotonin and dopamine) and fluorescence (glutamate and gaba) hplc detection. |
2018-06-08 |
2023-08-13 |
mouse |
| Patrícia P Silveira, Irina Pokhvisneva, Carine Parent, Shirong Cai, Anu Sathyan Sathyapalan Rema, Birit F P Broekman, Anne Rifkin-Graboi, Michael Pluess, Kieran J O'Donnell, Michael J Meane. Cumulative prenatal exposure to adversity reveals associations with a broad range of neurodevelopmental outcomes that are moderated by a novel, biologically informed polygenetic score based on the serotonin transporter solute carrier family C6, member 4 (SLC6A4) gene expression. Development and psychopathology. vol 29. issue 5. 2018-06-06. PMID:29162172. |
a genetic score based on genes coexpressed with the serotonin transporter in the amygdala, hippocampus, and prefrontal cortex during prenatal life was constructed with an emphasis on functionally relevant single nucleotide polymorphisms, that is, expression quantitative trait loci. |
2018-06-06 |
2023-08-13 |
Not clear |
| Liangcai Gao, Xinnan Liu, Li Yu, Junlin Wu, Mingchu Xu, Yusi Li. Folic acid exerts antidepressant effects by upregulating brain-derived neurotrophic factor and glutamate receptor 1 expression in brain. Neuroreport. vol 28. issue 16. 2018-06-04. PMID:28906345. |
our results showed that cums caused significant depression-like behaviors, neuropathological changes, and decreased brain 5-ht concentration, bdnf, and glur1 expression in the hippocampus and association cortex. |
2018-06-04 |
2023-08-13 |
rat |
| Dong-Sheng Wang, Jing Han, Shuo Li, Ting Sun, Yan-Yan Guo, Wen-Bo Kang, Zhen Tian, Jian-Ning Zhao, Gang Liu, Shui-Bing Liu, Ming-Gao Zha. Antidepressant-Like and Anxiolytic-Like Effects of ZBD-2, a Novel Ligand for the Translocator Protein (18 kDa). Neuromolecular medicine. vol 19. issue 1. 2018-05-28. PMID:27544207. |
treatment of zbd-2 reversed the decrease in biogenic amines (norepinephrine, dopamine, and serotonin) in the brain region of hippocampus in the ucms mice. |
2018-05-28 |
2023-08-13 |
mouse |
| Masatoshi Yamashita, Takanobu Yamamot. Tryptophan circuit in fatigue: From blood to brain and cognition. Brain research. vol 1675. 2018-05-22. PMID:28893581. |
results showed that compared to control group, presynaptic levels of tryptophan, kynurenine, and kynurenic acid, but not serotonin, in the cfsd group were higher in the hypothalamus and hippocampus. |
2018-05-22 |
2023-08-13 |
rat |