| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaomei Yang, Yue Yang, Feng Gao, Kangping Lu, Chunling Wan. N-Acetyl Serotonin Provides Neuroprotective Effects by Inhibiting Ferroptosis in the Neonatal Rat Hippocampus Following Hypoxic Brain Injury. Molecular neurobiology. 2023-07-14. PMID:37452222. |
n-acetyl serotonin provides neuroprotective effects by inhibiting ferroptosis in the neonatal rat hippocampus following hypoxic brain injury. |
2023-07-14 |
2023-08-14 |
rat |
| Haoxing Cai, Mingyue Chen, Yang Gao, Jinpeng Ruan, Chengyong He, Zhenghong Zu. Transgenerational Effects and Mechanisms of Tributyltin Exposure on Neurodevelopment in the Male Offspring of Rats. Environmental science & technology. 2023-07-05. PMID:37406193. |
additionally, f1-f3 males exhibited increased serotonin and dopamine levels and a loose arrangement of neurons in the hippocampus. |
2023-07-05 |
2023-08-14 |
rat |
| Huiwen Kang, Wei Zhang, Jiaru Jing, Danyang Huang, Lei Zhang, Jingyu Wang, Lin Han, Ziyan Liu, Ziyan Wang, Ai Ga. The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways. Journal of hazardous materials. vol 458. 2023-07-01. PMID:37392641. |
we found that 80 nm ps-nps could reach and cause neuronal damage in the hippocampus, and alter the expression of neuroplasticity-related molecules (5-ht, ache, gaba, bdnf and creb), and even affect the learning and memory ability of mice. |
2023-07-01 |
2023-08-14 |
mouse |
| Ruixi Yang, Suzhen Ye, Shuping Zhang, Hanjin Huang, Yun Zhang, Yao Yang, Shu Xie, Lin He, Yuwei Yang, Jian Sh. Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson's disease. Neuroreport. vol 34. issue 11. 2023-06-29. PMID:37384936. |
in our murine model, mptp induced a decreased level of 5-hydroxytryptamine and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the prefrontal cortex, hippocampus, and striatum (all p < 0.05); however, it only induced a decreased level of dopamine and its metabolite homovanillic acid (hva) in the striatum (both p < 0.001), with a negative correlation in the hippocampus and a positive correlation in the cortex and striatum. |
2023-06-29 |
2023-08-14 |
mouse |
| Junxi Fu, Wentian Song, Xiaobing Song, Li Fang, Xiyan Wang, Yue Leng, Ji Wang, Chunlei Liu, Weihong Mi. Synergistic Effect of Combined Walnut Peptide and Ginseng Extracts on Memory Improvement in C57BL/6 Mice and Potential Mechanism Exploration. Foods (Basel, Switzerland). vol 12. issue 12. 2023-06-28. PMID:37372540. |
improvement in the morphology of hippocampal neurons, dendritic spines, and synaptic plasticity and upregulation of neurotransmitters ache, ach, chat, glu, da, and 5-ht supported the memory improvement effects of wnp + gse. |
2023-06-28 |
2023-08-14 |
mouse |
| Kun Zhang, Yanfei Han, Peng Zhang, Yuqiong Zheng, Aobing Chen. Comparison of fluorescence biosensors and whole-cell patch clamp recording in detecting ACh, NE, and 5-HT. Frontiers in cellular neuroscience. vol 17. 2023-06-19. PMID:37333890. |
in this study, a multiplexed method was developed to measure acetylcholine (ach), norepinephrine (ne), and serotonin (5-ht) in cultured rat hippocampal slices using simultaneous whole-cell patch clamp recordings and genetically encoded fluorescence sensor imaging. |
2023-06-19 |
2023-08-14 |
rat |
| Min-Kyung Joo, Dong-Hyun Ki. Vagus nerve-dependent effects of fluoxetine on anxiety- and depression-like behaviors in mice. European journal of pharmacology. 2023-06-18. PMID:37331682. |
the vagotomy also inhibited the effect of fluoxetine to attenuate restraint stress- or cefaclor-induced reduction in serotonin levels and htr1a mrna expression in the hippocampus. |
2023-06-18 |
2023-08-14 |
mouse |
| Sharafuddin Khairuddin, Wei Ling Lim, Luca Aquili, Ka Chun Tsui, Anna Chung-Kwan Tse, Shehani Jayalath, Ruhani Varma, Trevor Sharp, Abdelhamid Benazzouz, Harry Steinbusch, Arjan Blokland, Yasin Temel, Lee Wei Li. Prelimbic Cortical Stimulation Induces Antidepressant-like Responses through Dopaminergic-Dependent and -Independent Mechanisms. Cells. vol 12. issue 11. 2023-06-11. PMID:37296570. |
hfs prl in both the cus-susceptible and cus-resilient animals significantly increased hedonia, reduced anxiety, decreased forced swim immobility, enhanced hippocampal da and serotonin levels, and reduced corticosterone levels when compared with the respective sham groups. |
2023-06-11 |
2023-08-14 |
rat |
| Shufang Xia, Gusonghan Maitiniyazi, Yuan Liu, Yue Chen, Mengting Guo, Jianyun He, Wei Tao, Ziyuan L. Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor. Food research international (Ottawa, Ont.). vol 169. 2023-05-31. PMID:37254425. |
increasing evidence indicates that tryptophan (trp) metabolism disturbance controls hippocampal 5-hydroxytryptamine (5-ht) and thereby affecting depression-like behavior, in which the gut microbiota (gm) might be involved. |
2023-05-31 |
2023-08-14 |
mouse |
| Shufang Xia, Gusonghan Maitiniyazi, Yuan Liu, Yue Chen, Mengting Guo, Jianyun He, Wei Tao, Ziyuan L. Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor. Food research international (Ottawa, Ont.). vol 169. 2023-05-31. PMID:37254425. |
moreover, wpi promoted the hippocampal trp, 5-hydroxytryptophan (5-htp), 5-ht, 5-hydroxyindoleacetic acid (5-hiaa) levels and inhibited kynurenine (kyn) through up-regulating serotonin transporter (sert) and down-regulating indoleamine 2, 3-dioxygenase (ido). |
2023-05-31 |
2023-08-14 |
mouse |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
they also showed significant decreases in the levels of l-tyrosine, norepinephrine, vanillylmandelic acid, 5-hydroxytryptamine, and acetylcholine, in contrast to significant increases in 5-hydroxyindoleacetic acid, l-histidine, l-glutamine, and l-arginine in the hippocampus. |
2023-05-31 |
2023-08-14 |
mouse |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
moreover, the expression of the alpha 1a adrenergic receptor (adra1a), serotonin 1 a receptor (5ht1a), and γ-aminobutyric acid a receptor subunit alpha-2 (gabra2) was significantly downregulated in the hippocampus of 3×tg-ad mice, while histamine h3 receptor (h3r) expression was significantly upregulated. |
2023-05-31 |
2023-08-14 |
mouse |
| Amine Bahi, Jean-Luc Dreye. Anxiety and Ethanol Consumption in Socially Defeated Mice; Effect of Hippocampal Serotonin Transporter Knockdown. Behavioural brain research. 2023-05-27. PMID:37244437. |
anxiety and ethanol consumption in socially defeated mice; effect of hippocampal serotonin transporter knockdown. |
2023-05-27 |
2023-08-14 |
mouse |
| Hiromi Shiozaki, Nahoko Kuga, Tasuku Kayama, Yuji Ikegaya, Takuya Sasak. Selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. Journal of pharmacological sciences. vol 152. issue 2. 2023-05-11. PMID:37169478. |
selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. |
2023-05-11 |
2023-08-14 |
Not clear |
| Hiromi Shiozaki, Nahoko Kuga, Tasuku Kayama, Yuji Ikegaya, Takuya Sasak. Selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. Journal of pharmacological sciences. vol 152. issue 2. 2023-05-11. PMID:37169478. |
administration of the selective serotonin reuptake inhibitors (ssris) fluoxetine and fluvoxamine inhibited the generation of ventral hippocampal swrs and reduced locomotor activity and local field potential power in the gamma bands. |
2023-05-11 |
2023-08-14 |
Not clear |
| Wenyan Xian, Yu Deng, Yuzhe Yang, Zhaolun Tan, Chunlian Chen, Wu Li, Ruili Yan. Ameliorative Effect of Ellagic Acid on Aging in Rats with the Potential Mechanism Relying on the Gut Microbiota and Urolithin A-Producing Ability. Journal of agricultural and food chemistry. 2023-05-03. PMID:37132992. |
our results showed that ea improved cognitive impairment and hippocampal damage, increased the gaba (by 107.84-117.86%) and 5-ht (by 72.56-100.85%) levels, and suppressed the inflammatory and oxidative stress in aging rats. |
2023-05-03 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
5ht1ar-fgfr1 heteroreceptor complexes differently modulate girk currents in the dorsal hippocampus and the dorsal raphe serotonin nucleus of control rats and of a genetic rat model of depression. |
2023-04-28 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
the midbrain raphe serotonin (5ht) neurons provide the main ascending serotonergic projection to the forebrain, including hippocampus, which has a role in the pathophysiology of depressive disorder. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
we examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of neurotransmitters, including dopamine, serotonin, glutamate, glutamine, and gaba in the amygdala and hippocampus. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
dopamine, serotonin, glutamate, glutamine, and gaba were extracted from both the amygdala and hippocampus and were separated and quantified using a developed and validated hplc-ms/ms method. |
2023-04-28 |
2023-08-14 |
rat |