| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abdelaziz M Hussein, Khaled M Abbas, Osama A Abulseoud, El-Hussainy M A El-Hussain. Effects of ferulic acid on oxidative stress, heat shock protein 70, connexin 43, and monoamines in the hippocampus of pentylenetetrazole-kindled rats. Canadian journal of physiology and pharmacology. vol 95. issue 6. 2018-01-09. PMID:28177659. |
ptz caused a significant increase in mda, cx43, and hsp70 along with a significant decrease in gsh, 5-ht, and ne levels and cat activity in the hippocampus (p < 0.05). |
2018-01-09 |
2023-08-13 |
rat |
| Abdelaziz M Hussein, Khaled M Abbas, Osama A Abulseoud, El-Hussainy M A El-Hussain. Effects of ferulic acid on oxidative stress, heat shock protein 70, connexin 43, and monoamines in the hippocampus of pentylenetetrazole-kindled rats. Canadian journal of physiology and pharmacology. vol 95. issue 6. 2018-01-09. PMID:28177659. |
pre- and post-treatment with fa caused significant improvement in behavioral parameters, mda, cat, gsh, 5-ht, ne, cx43 expression, and hsp70 expression in the hippocampal region (p < 0.05). |
2018-01-09 |
2023-08-13 |
rat |
| Daniel R Wyskiel, Rodrigo Andrad. Serotonin excites hippocampal CA1 GABAergic interneurons at the stratum radiatum-stratum lacunosum moleculare border. Hippocampus. vol 26. issue 9. 2018-01-08. PMID:27328460. |
these results indicate that serotonin interneurons expressing 5-ht2a rs are localized primarily along the sr-slm border of the ca1 region and represent a newly identified target for serotonin regulation in the hippocampus. |
2018-01-08 |
2023-08-13 |
mouse |
| Hannah Twarkowski, Hardy Hagena, Denise Manahan-Vaugha. The 5-hydroxytryptamine4 receptor enables differentiation of informational content and encoding in the hippocampus. Hippocampus. vol 26. issue 7. 2018-01-08. PMID:26800645. |
neuromodulators such as serotonin regulate hippocampal function, and the 5-ht4 -receptor contributes to processes underlying cognition. |
2018-01-08 |
2023-08-13 |
rat |
| Sebastian P Fernandez, Aude Muzerelle, Sophie Scotto-Lomassese, Jacques Barik, Agnès Gruart, José M Delgado-García, Patricia Gaspa. Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27461084. |
constitutive and acquired serotonin deficiency alters memory and hippocampal synaptic plasticity. |
2018-01-05 |
2023-08-13 |
mouse |
| Amy S Kohtz, Gary Aston-Jone. Cocaine Seeking During Initial Abstinence Is Driven by Noradrenergic and Serotonergic Signaling in Hippocampus in a Sex-Dependent Manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27515792. |
the dorsal hippocampus (dh) is prominently involved in the stress response, as are the locus coeruleus norepinephrine (lc-ne) and dorsal raphe serotonin (dr 5-ht) systems. |
2018-01-05 |
2023-08-13 |
rat |
| Mohammad Nasehi, Maryam Farrahizadeh, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Reza Zarrindas. Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning. Journal of psychopharmacology (Oxford, England). vol 30. issue 9. 2018-01-04. PMID:27296273. |
to clarify the interaction between the hippocampal serotonin (5-ht4) receptor and the cannabinoid cb1 receptor in the acquisition of fear memory, the effects of 5-ht4 agents, arachidonylcyclopropylamide (acpa; cb1 receptor agonist), and the combined use of these drugs on fear learning were studied in a fear conditioning task in adult male nmri mice. |
2018-01-04 |
2023-08-13 |
mouse |
| Yurii A Zolotarev, Georgii I Kovalev, Natalya V Kost, Margarita E Voevodina, Oleg Y Sokolov, Alexander K Dadayan, Evgenii A Kondrakhin, Ekaterina V Vasileva, Anna P Bogachuk, Vyacheslav N Azev, Valery M Lipkin, Nikolai F Myasoedo. Anxiolytic activity of the neuroprotective peptide HLDF-6 and its effects on brain neurotransmitter systems in BALB/c and C57BL/6 mice. Journal of psychopharmacology (Oxford, England). vol 30. issue 9. 2018-01-04. PMID:27464742. |
the mechanism of the specific anxiolytic activity of hldf-6-amide may include its action on the nmda-glutamatergic receptor system of the hippocampus and on serotonin 5-ht2a-receptors in the prefrontal cortex. |
2018-01-04 |
2023-08-13 |
mouse |
| Timothy R Powell, Tytus Murphy, Sang H Lee, Jack Price, Sandrine Thuret, Gerome Bree. Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning. Journal of psychopharmacology (Oxford, England). vol 31. issue 3. 2018-01-04. PMID:28208023. |
we investigated genome-wide transcriptomic changes to human hippocampal progenitor cells treated with therapeutically relevant concentrations of a tricyclic antidepressant (nortriptyline) and a selective serotonin reuptake inhibitor (escitalopram). |
2018-01-04 |
2023-08-13 |
human |
| V Marasco, P Herzyk, J Robinson, K A Spence. Pre- and Post-Natal Stress Programming: Developmental Exposure to Glucocorticoids Causes Long-Term Brain-Region Specific Changes to Transcriptome in the Precocial Japanese Quail. Journal of neuroendocrinology. vol 28. issue 5. 2018-01-04. PMID:26999292. |
brain-derived neurotrophic factor and mineralocorticoid receptor within the hippocampus; corticotrophin-releasing hormone and serotonin receptors in the hypothalamus). |
2018-01-04 |
2023-08-13 |
Not clear |
| Alberto Rubio-Casillas, Alonso Fernández-Guast. The dose makes the poison: from glutamate-mediated neurogenesis to neuronal atrophy and depression. Reviews in the neurosciences. vol 27. issue 6. 2018-01-02. PMID:27096778. |
additionally, it has been shown that chronic treatment with antidepressants having divergent mechanisms of action (including tricyclics, selective serotonin reuptake inhibitors, and ketamine) markedly reduced depolarization-evoked glutamate release in the hippocampus. |
2018-01-02 |
2023-08-13 |
Not clear |
| Keng-Fan Liu, Yingxiao Li, Kai Chun Cheng, Chao Chin Hsu, Juei-Tang Cheng, Wen-Huang Pen. Changes in PPARδ expression in a rat model of stress-induced depression. Clinical and experimental pharmacology & physiology. vol 44. issue 6. 2018-01-01. PMID:28267873. |
treatment with a pparδ agonist enhanced the expression of pparδ and the serotonin transporter in the hippocampus of rats with stress-induced depression. |
2018-01-01 |
2023-08-13 |
rat |
| Keng-Fan Liu, Yingxiao Li, Kai Chun Cheng, Chao Chin Hsu, Juei-Tang Cheng, Wen-Huang Pen. Changes in PPARδ expression in a rat model of stress-induced depression. Clinical and experimental pharmacology & physiology. vol 44. issue 6. 2018-01-01. PMID:28267873. |
additionally, treatment with a pparδ agonist increased the expression of the serotonin transporter in cultured hippocampal (h19-7) cells, and this action was ablated in the absence of pparδ, which was attenuated with shrna. |
2018-01-01 |
2023-08-13 |
rat |
| H Azizi, J Hwang, V Suen, N Z Kang, R Somvanshi, R Tadavarty, U Kumar, B R Sastr. Sleep deprivation induces changes in 5-HT actions and 5-HT Neuroscience letters. vol 655. 2018-01-01. PMID:28668380. |
sleep deprivation induces changes in 5-ht actions and 5-ht a 12h sleep deprivation enhances the expression of 5-hydroxytryptamine (5-ht) 1a receptors in rat hippocampus that recedes with 48h sleep recovery. |
2018-01-01 |
2023-08-13 |
rat |
| Meng-Yan Zhan. Establishment of a BALB/c Mouse Model for Assessing the Degree of Inebriation Induced by Luzhou-Flavor Liquors. Journal of AOAC International. vol 100. issue 5. 2017-12-28. PMID:28477404. |
the blood ethanol concentration, blood acetaldehyde concentration, acetylcholinesterase activity in the hippocampus, and concentrations of dopamine and serotonin in the striatum were also determined. |
2017-12-28 |
2023-08-13 |
mouse |
| Meng-Yan Zhan. Establishment of a BALB/c Mouse Model for Assessing the Degree of Inebriation Induced by Luzhou-Flavor Liquors. Journal of AOAC International. vol 100. issue 5. 2017-12-28. PMID:28477404. |
moreover, it had no significant effects on acetylcholinesterase activity in the hippocampus or on the concentrations of dopamine or serotonin in the striatum. |
2017-12-28 |
2023-08-13 |
mouse |
| Tomas Furmark, Ina Marteinsdottir, Andreas Frick, Kerstin Heurling, Maria Tillfors, Lieuwe Appel, Gunnar Antoni, Per Hartvig, Håkan Fischer, Bengt Långström, Elias Eriksson, Mats Fredrikso. Serotonin synthesis rate and the tryptophan hydroxylase-2: G-703T polymorphism in social anxiety disorder. Journal of psychopharmacology (Oxford, England). vol 30. issue 10. 2017-12-28. PMID:27189957. |
a significantly elevated [(11)c]5-htp accumulation rate, indicative of enhanced decarboxylase activity and thereby serotonin synthesis capacity, was detected in social anxiety disorder patients compared with controls in the hippocampus and basal ganglia nuclei and, at a more lenient (uncorrected) statistical threshold, in the amygdala and anterior cingulate cortex. |
2017-12-28 |
2023-08-13 |
Not clear |
| Andiara E Freitas, Javier Egea, Izaskun Buendia, Vanessa Gómez-Rangel, Esther Parada, Elisa Navarro, Ana Isabel Casas, Aneta Wojnicz, José Avendaño Ortiz, Antonio Cuadrado, Ana Ruiz-Nuño, Ana Lúcia S Rodrigues, Manuela G Lope. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. Molecular neurobiology. vol 53. issue 5. 2017-12-25. PMID:25966970. |
in addition, agmatine treatment in control mice increased noradrenaline, serotonin, and dopamine levels, creb phosphorylation, mature bdnf and synaptotagmin i immunocontents, and reduced pro-bdnf immunocontent in the hippocampus. |
2017-12-25 |
2023-08-13 |
mouse |
| Kristian Gaarn Du Jardin, Heidi Kaastrup Müller, Connie Sanchez, Gregers Wegener, Betina Elfvin. Gene expression related to serotonergic and glutamatergic neurotransmission is altered in the flinders sensitive line rat model of depression: Effect of ketamine. Synapse (New York, N.Y.). vol 71. issue 1. 2017-12-22. PMID:27589698. |
relative to frl rats, fsl rats displayed enhanced hippocampal transcript levels of 5-ht |
2017-12-22 |
2023-08-13 |
rat |
| Isabella Caroline da Silva Dias, Bruno Carabelli, Daniela Kaori Ishii, Helen de Morais, Milene Cristina de Carvalho, Luiz E Rizzo de Souza, Silvio M Zanata, Marcus Lira Brandão, Thiago Mattar Cunha, Anete Curte Ferraz, Joice Maria Cunha, Janaina Menezes Zanovel. Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes. Molecular neurobiology. vol 53. issue 10. 2017-12-22. PMID:26671617. |
to test this hypothesis, diabetic (dbt) and normoglycemic (ngl) groups had the cytokines (tnfα, il-1β, and il-6) and 5-ht and norepinephrine (ne) levels in the hippocampus (hip) evaluated. |
2017-12-22 |
2023-08-13 |
rat |