All Relations between hippocampus and serotonin

Reference Sentence Publish Date Extraction Date Species
J B\\xc3\\xa9\\xc3\\xafque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology vol 39 issue 10 2000 10884562 the effects of long-term administrations of a low (10 mg/kg/day) and a high (40 mg/kg/day) dose of the dual 5-ht and ne reuptake inhibitor venlafaxine (delivered s.c. by osmotic minipumps for 21 days) were assessed on the electrically-evoked release of tritium from hippocampal slices preloaded with either [(3)h]5-ht or [(3)h]ne, 48 h after the removal of the minipump. 2000-09-28 2022-01-11 Not clear
J B\\xc3\\xa9\\xc3\\xafque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology vol 39 issue 10 2000 10884562 none of the treatment regimens altered the basal uptake of [(3)h]5-ht from hippocampal or mesencephalic slices nor that of [(3)h]ne from hippocampal slices. 2000-09-28 2022-01-11 Not clear
J B\\xc3\\xa9\\xc3\\xafque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology vol 39 issue 10 2000 10884562 finally, the enhancing effect of 1 microm of paroxetine in the perfusion medium on the electrical release of [(3)h]5-ht was unaltered in hippocampal slices prepared from rats that had been treated for 21 days with 40 mg/kg/day of venlafaxine. 2000-09-28 2022-01-11 Not clear
C Martin, M Duclos, P Morm\\xc3\\xa8de, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters vol 288 issue 3 2000 10889353 hippocampal and striatal [(3)h]5-ht reuptake under acute stressors in two rat strains differing for their emotivity. 2000-09-28 2022-01-11 Not clear
C Martin, M Duclos, P Morm\\xc3\\xa8de, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters vol 288 issue 3 2000 10889353 since the 5-ht transporter plays a key role in 5-ht neurotransmission, we have analyzed whether hippocampal and/or striatal [(3)h]5-ht reuptake kinetics are altered by stress in a strain-dependent manner. 2000-09-28 2022-01-11 Not clear
C Martin, M Duclos, P Morm\\xc3\\xa8de, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters vol 288 issue 3 2000 10889353 it was found that forced swimming, treadmill running, or restraint for 30 min affected neither hippocampal nor striatal [(3)h]5-ht reuptake k(m) and v(max) values in the two rat strains. 2000-09-28 2022-01-11 Not clear
A S\\xc3\\xa9mont, M Fache, F H\\xc3\\xa9ry, M Faudon, F Youssouf, M H\\xc3\\xa9r. Regulation of central corticosteroid receptors following short-term activation of serotonin transmission by 5-hydroxy-L-tryptophan or fluoxetine. Journal of neuroendocrinology vol 12 issue 8 2000 10929085 these results show that short-term stimulation of 5-ht transmission by 5-htp decreases hippocampal and hypothalamic corticosteroid receptor numbers through a corticosterone-independent mechanism. 2000-09-06 2022-01-11 Not clear
W L Bacon, S G Bec. 5-Hydroxytryptamine(7) receptor activation decreases slow afterhyperpolarization amplitude in CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 294 issue 2 2000 10900247 5-hydroxytryptamine(7) receptor activation decreases slow afterhyperpolarization amplitude in ca3 hippocampal pyramidal cells. 2000-08-24 2022-01-11 Not clear
W L Bacon, S G Bec. 5-Hydroxytryptamine(7) receptor activation decreases slow afterhyperpolarization amplitude in CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics vol 294 issue 2 2000 10900247 based on the rank order potency of the agonists and antagonists, one of the receptors that mediates the decrease in sahp amplitude in ca3 hippocampal pyramidal cells was concluded to be the 5-ht(7) receptor. 2000-08-24 2022-01-11 Not clear
H C Akunne, K T Zoski, M D Davis, L W Cooke, L T Meltzer, S Z Whetzel, Y H Shih, D J Wustrow, L D Wise, R G MacKenzie, L M Georgic, T G Heffner, T A Pugsle. PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects. Neuropharmacology vol 39 issue 7 2000 10760362 pd 158771 showed high affinity for cloned human 5-ht(1a) (k(i) = 2.6 nm) and rat hippocampal 5-ht(1a) receptors (k(i) = 3.5 nm). 2000-08-15 2022-01-11 Not clear
J J Hagan, G W Price, P Jeffrey, N J Deeks, T Stean, D Piper, M I Smith, N Upton, A D Medhurst, D N Middlemiss, G J Riley, P J Lovell, S M Bromidge, D R Thoma. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. British journal of pharmacology vol 130 issue 3 2000 10821781 5-ct-stimulated adenylyl cyclase activity in guinea-pig hippocampal membranes (pec(50) of 8.4+/-0.2) was inhibited by sb-269970-a (0.3 microm) with a pk(b) (8.3+/-0.1) in good agreement with its antagonist potency at the human cloned 5-ht(7(a)) receptor and its binding affinity at guinea-pig cortical membranes. 2000-08-01 2022-01-11 Not clear
S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior vol 66 issue 1 2000 10837844 a review of the literature suggests that the dorsal hippocampal serotonergic system, and, in particular, the postsynaptic 5-ht(1a) receptor, mediates an anxiogenic response, whereas endogenous dorsal hippocampal cholinergic tone mediates an anxiolytic response. 2000-07-06 2022-01-11 Not clear
S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior vol 66 issue 1 2000 10837844 accordingly, it has been shown that direct dorsal hippocampal administration of the 5-ht(1a) receptor agonist, 8-oh-dpat, the nicotinic receptor antagonist, mecamylamine, and the m(1) muscarinic receptor antagonist, pirenzepine, all have anxiogenic effects in rats tested in the social interaction test. 2000-07-06 2022-01-11 Not clear
S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior vol 66 issue 1 2000 10837844 however, the anxiogenic effects of mecamylamine and nicotine in the dorsal hippocampus are blocked by coadministration of the 5-ht(1a) receptor antagonist, way 100635, suggesting that both of these compounds act by enhancing hippocampal serotonergic transmission, thereby stimulating postsynaptic 5-ht(1a) receptors. 2000-07-06 2022-01-11 Not clear
S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior vol 66 issue 1 2000 10837844 a possible mechanism by which nicotinic receptor ligands modulate hippocampal 5-ht release is discussed, and it is proposed that the dorsal hippocampal serotonergic and cholinergic systems are tightly coupled and function antagonistically in the modulation of anxiety, as measured in the social interaction test. 2000-07-06 2022-01-11 Not clear
J Farisse, F H\\xc3\\xa9ry, N Barden, M H\\xc3\\xa9ry, P Boulengue. Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number. Brain research vol 862 issue 1-2 2000 10799679 we found that 1 nm [3h]8-hydroxy-2-[di-n-propylamino]tetralin ([3h]8-oh-dpat) binding to 5-ht(1a) sites was decreased in strata oriens (-15.1+/-3.5%) and radiatum-lacunosum-moleculare (-13.3+/-4.3%) of the hippocampal ca(3) area, and 2 nm [3h]5-hydroxytryptamine binding to 5-ht(1nona) sites in the presence of 100 nm 8-oh-dpat and mesulergine was decreased in the dorsal subiculum (-17.8+/-6.9%). 2000-06-21 2022-01-11 Not clear
P Bonaventure, H Hall, W Gommeren, P Cras, X Langlois, M Jurzak, J E Leyse. Mapping of serotonin 5-HT(4) receptor mRNA and ligand binding sites in the post-mortem human brain. Synapse (New York, N.Y.) vol 36 issue 1 2000 10700024 in the in situ hybridization study, the highest levels of 5-ht(4) receptor mrna were found in caudate nucleus, putamen, nucleus accumbens, and in the hippocampal formation. 2000-06-02 2022-01-10 Not clear
T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin vol 51 issue 6 2000 10758340 5ht(2a) receptor immunolabeling was also observed in gfap-positive cells of the various brain structures we investigated (layers i/vi of the neocortex, corpus callosum, hippocampal fissure and hilus, and amygdala). 2000-05-31 2022-01-11 Not clear
M J Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, J R Seck. Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 20 issue 10 2000 10804232 in primary hippocampal cell cultures, serotonin (5-ht) increases glucocorticoid receptor expression, and this effect appears to be mediated by increased camp levels. 2000-05-25 2022-01-11 Not clear
M J Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, J R Seck. Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 20 issue 10 2000 10804232 in 7-d-old rat pups, we found that (1) postnatal handling increased adenylyl cyclase activity and hippocampal camp levels, (2) the effect of handling on camp levels was completely blocked by treatment with either propylthiouracil (ptu), a thyroid hormone synthesis inhibitor, or the 5-ht receptor antagonist, ketanserin, and (3) handling also increased hippocampal pka activity. 2000-05-25 2022-01-11 Not clear
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