| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gongliang Zhang, David Cinalli, Sarah J Cohen, Kristina D Knapp, Lisa M Rios, José Martínez-Hernández, Rafael Luján, Robert W Stackma. Examination of the hippocampal contribution to serotonin 5-HT2A receptor-mediated facilitation of object memory in C57BL/6J mice. Neuropharmacology. vol 109. 2017-06-19. PMID:27114257. |
serotonin 5-ht2a receptors (5-ht2ar) are widely expressed throughout the hippocampus. |
2017-06-19 |
2023-08-13 |
mouse |
| Hyun-Ja Jeong, Shi-Young Yang, Hee-Yun Kim, Na-Rae Kim, Jae-Bum Jang, Hyung-Min Ki. Chelidonic acid evokes antidepressant-like effect through the up-regulation of BDNF in forced swimming test. Experimental biology and medicine (Maywood, N.J.). vol 241. issue 14. 2017-06-14. PMID:27037280. |
in addition, chelidonic acid significantly increased the levels of 5-hydroxytryptamine (serotonin), dopamine, and norepinephrine compared with those levels for the mice that were administered distilled water in the hippocampus. |
2017-06-14 |
2023-08-13 |
mouse |
| Xue-Run Chang, Li Wang, Jing Li, Dian-Shui W. Analysis of anti-depressant potential of curcumin against depression induced male albino wistar rats. Brain research. vol 1642. 2017-05-23. PMID:26972530. |
chronic administration of curcumin significantly reversed levels of 3, 4-dihydroxyphenylacetic acid, noradrenaline, serotonin and 5-hydroxyindoleacetic acid in the hippocampus region of male albino rats. |
2017-05-23 |
2023-08-13 |
rat |
| Jolien Van Schoors, Johan Viaene, Yannick Van Wanseele, Ilse Smolders, Bieke Dejaegher, Yvan Vander Heyden, Ann Van Eeckhau. An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples. Journal of pharmaceutical and biomedical analysis. vol 127. 2017-05-15. PMID:26809614. |
the sensitive uhplc-ecd assay (lloq of 100pm for na and 150pm for da and 5-ht) with an analysis time of 8min for standard solutions and 20min for in vivo microdialysis samples originating from rat hippocampus, prefrontal cortex and striatum, is validated applying accuracy profiles. |
2017-05-15 |
2023-08-13 |
rat |
| Hongli Du, Keqing Wang, Li Su, Hongxia Zhao, Songyan Gao, Qishan Lin, Xiaofang Ma, Baokang Zhu, Xin Dong, Ziyang Lo. Metabonomic identification of the effects of the Zhimu-Baihe saponins on a chronic unpredictable mild stress-induced rat model of depression. Journal of pharmaceutical and biomedical analysis. vol 128. 2017-05-15. PMID:27371920. |
high performance liquid chromatography with electrochemical detection (hplc-ecd) was applied to determine the levels of three monoamine neurotransmitters, 5-hydroxytryptamine (5-ht), noradrenaline (ne) and dopamine (da), in the rat hippocampus. |
2017-05-15 |
2023-08-13 |
rat |
| Ju-Ryun Na, Dool-Ri Oh, SeulHee Han, Yu-Jin Kim, EunJin Choi, Donghyuck Bae, Dong Hwan Oh, Yoo-Hyun Lee, Sunoh Kim, Woojin Ju. Antistress Effects of Rosa rugosa Thunb. on Total Sleep Deprivation-Induced Anxiety-Like Behavior and Cognitive Dysfunction in Rat: Possible Mechanism of Action of 5-HT6 Receptor Antagonist. Journal of medicinal food. vol 19. issue 9. 2017-05-05. PMID:27331439. |
this study aimed to screen and identify the physiological antistress effects of an extract of r. rugosa (ro) on sleep deprivation-induced anxiety-like behavior and cognitive tests (in vivo) and tested for hippocampal cort and monoamine levels (ex vivo), corticosterone (cort)-induced injury, n-methyl-d-aspartate (nmda) receptor, and serotonin 6 (5-hydroxytryptamine 6, 5-ht6) receptor activities (in vitro) in search of active principles and underlying mechanisms of action. |
2017-05-05 |
2023-08-13 |
rat |
| Bhagyashree D Rao, Sandeep Shrivastava, Amitabha Chattopadhya. Effect of local anesthetics on serotonin Chemistry and physics of lipids. vol 201. 2017-05-02. PMID:27825964. |
in this work, we have explored the effect of petoh on the function of the hippocampal serotonin |
2017-05-02 |
2023-08-13 |
Not clear |
| Martin J Brodie, Frank Besag, Alan B Ettinger, Marco Mula, Gabriella Gobbi, Stefano Comai, Albert P Aldenkamp, Bernhard J Steinhof. Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review. Pharmacological reviews. vol 68. issue 3. 2017-04-20. PMID:27255267. |
we review the common neurotransmitter systems and brain regions implicated in both epilepsy and aggression, including the gaba, glutamate, serotonin, dopamine, and noradrenaline systems and the hippocampus, amygdala, prefrontal cortex, anterior cingulate cortex, and temporal lobes. |
2017-04-20 |
2023-08-13 |
Not clear |
| Mohit Kwatra, Ashok Jangra, Murli Mishra, Yogita Sharma, Sahabuddin Ahmed, Pinaki Ghosh, Vikas Kumar, Divya Vohora, Razia Khana. Naringin and Sertraline Ameliorate Doxorubicin-Induced Behavioral Deficits Through Modulation of Serotonin Level and Mitochondrial Complexes Protection Pathway in Rat Hippocampus. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27209303. |
naringin and sertraline ameliorate doxorubicin-induced behavioral deficits through modulation of serotonin level and mitochondrial complexes protection pathway in rat hippocampus. |
2017-04-17 |
2023-08-13 |
rat |
| Zhong-Min Wu, Li-Hua Yang, Rong Cui, Gui-Lian Ni, Feng-Tian Wu, Yong Lian. Contribution of Hippocampal 5-HT Cellular and molecular neurobiology. vol 37. issue 4. 2017-04-17. PMID:27324798. |
contribution of hippocampal 5-ht one of the hypotheses about the pathogenesis of posttraumatic stress disorder (ptsd) is the dysfunction of serotonin (5-ht) neurotransmission. |
2017-04-17 |
2023-08-13 |
Not clear |
| Katarzyna Jawna-Zboińska, Kamilla Blecharz-Klin, Ilona Joniec-Maciejak, Adriana Wawer, Justyna Pyrzanowska, Agnieszka Piechal, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Passiflora incarnata L. Improves Spatial Memory, Reduces Stress, and Affects Neurotransmission in Rats. Phytotherapy research : PTR. vol 30. issue 5. 2017-03-30. PMID:26814055. |
in addition, hippocampal glutamic acid and cortical serotonin content were depleted, with increased levels of metabolites and increased turnover. |
2017-03-30 |
2023-08-13 |
rat |
| M Vázquez-Gómez, D Valent, C García-Contreras, L Arroyo, C Óvilo, B Isabel, A Bassols, A González-Bulne. Sex and intrauterine growth restriction modify brain neurotransmitters profile of newborn piglets. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 55. 2017-03-28. PMID:27616302. |
the effects of iugr were modulated by sex; there were no significant differences between lbw and nbw females, but lbw males had higher hva concentration at the amygdala and higher concentration of 5-hydroxyindoleacetic acid, the serotonin metabolite, at the hippocampus than nbw males. |
2017-03-28 |
2023-08-13 |
Not clear |
| Jana D Tchekalarova, Natasha Ivanova, Dimitrina Atanasova, Daniela M Pechlivanova, Nikolai Lazarov, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Alexander Stoyne. Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. Cellular and molecular neurobiology. vol 36. issue 6. 2017-03-22. PMID:26464042. |
the levels of serotonin in the hippocampus and neuronal loss were estimated by hplc and hematoxylin and eosin staining, respectively. |
2017-03-22 |
2023-08-13 |
rat |
| Jana D Tchekalarova, Natasha Ivanova, Dimitrina Atanasova, Daniela M Pechlivanova, Nikolai Lazarov, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Alexander Stoyne. Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. Cellular and molecular neurobiology. vol 36. issue 6. 2017-03-22. PMID:26464042. |
however, the at1 receptor antagonist did not exert a substantial influence on concomitant with epilepsy behavioral changes and decreased 5-ht levels in the hippocampus. |
2017-03-22 |
2023-08-13 |
rat |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
to address mechanisms underlying these effects, we used in vivo microdialysis study and observed impaired nicotine-induced serotonin (5-ht) release in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
combined memantine/donepezil administration, but not single administration of either, significantly antagonized the decrease in nicotine-induced 5-ht release seen in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
these results suggest that improvement of bpsd-like behaviors by the co-administration of both drugs is in part mediated by enhanced 5-ht release and camkii activity in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Hidemi Yasuda, Akiko Harauma, Maki Kato, Yuki Ootomo, Erisa Hatanaka, Toru Moriguch. Artificially reared mice exhibit anxiety-like behavior in adulthood. Experimental animals. vol 65. issue 3. 2017-03-13. PMID:26948536. |
the hippocampal norepinephrine, serotonin, and 5-hydroxyindoleacetic acid levels in the artificially reared mice were significantly higher than those of the dam-reared mice. |
2017-03-13 |
2023-08-13 |
mouse |
| Saroj Kumar Das, Manorama Patr. Neuropeptide Y expression confers benzo[a]pyrene induced anxiolytic like behavioral response during early adolescence period of male Wistar rats. Neuropeptides. vol 61. 2017-03-09. PMID:27402563. |
the neurotransmitter estimation by hplc-ecd showed significant increase in 5-ht level in both hippocampus and hypothalamus of b[a]p treated group. |
2017-03-09 |
2023-08-13 |
rat |
| Yan-Fang Xian, Ding Fan, Siu-Po Ip, Qing-Qiu Mao, Zhi-Xiu Li. Antidepressant-Like Effect of Isorhynchophylline in Mice. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27900600. |
in addition, irn treatment antagonized reserpine-induced ptosis and significantly enhanced the levels of monoamine neurotransmitters including norepinephrine (ne) and 5-hydroxytryptamine (5-ht), and the activity of monoamine oxidase a (mao-a) in the hippocampus and frontal cortex of mice. |
2017-03-07 |
2023-08-13 |
mouse |