| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
diminished levels of brain serotonin (5-ht) and increased levels of hippocampal brain-derived neurotrophic factor (bdnf) were found in the hypothyroid rats compared to the control saline-vehicle administered rats. |
2015-08-24 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
the hyperthyroid rats exhibited higher anxiety- and depression-like behaviors, higher brain 5-ht level, and lower hippocampal bdnf levels than the controls. |
2015-08-24 |
2023-08-13 |
rat |
| H Bielas, P Arck, C A Bruenahl, S Walitza, E Grünblat. Prenatal stress increases the striatal and hippocampal expression of correlating c-FOS and serotonin transporters in murine offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25102410. |
prenatal stress increases the striatal and hippocampal expression of correlating c-fos and serotonin transporters in murine offspring. |
2015-08-21 |
2023-08-13 |
mouse |
| Raúl López-Arnau, José Martínez-Clemente, Teresa Rodrigo, David Pubill, Jorge Camarasa, Elena Escubed. Neuronal changes and oxidative stress in adolescent rats after repeated exposure to mephedrone. Toxicology and applied pharmacology. vol 286. issue 1. 2015-08-05. PMID:25817894. |
mephedrone induced a reduction of the densities of dopamine (30% in the frontal cortex) and serotonin (40% in the frontal cortex and the hippocampus and 48% in the striatum) transporters without microgliosis. |
2015-08-05 |
2023-08-13 |
human |
| Minkyung Lee, Young Hoon Ryu, Won Gil Cho, Tae Joo Jeon, Chul Hyoung Lyoo, Yeo Wool Kang, Soo Jin Lee, Chul Hoon Kim, Dong Goo Kim, Jee Hae Kang, Young Beom Seo, Chi Hoon Yi, Kyochul Lee, Tae Hyun Choi, Jae Yong Cho. Dopaminergic neuron destruction reduces hippocampal serotonin 1A receptor uptake of trans-[(18)F]Mefway. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. vol 94. 2015-08-04. PMID:25064461. |
dopaminergic neuron destruction reduces hippocampal serotonin 1a receptor uptake of trans-[(18)f]mefway. |
2015-08-04 |
2023-08-13 |
rat |
| Jeanette C Valleau, Elinor L Sulliva. The impact of leptin on perinatal development and psychopathology. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:24862904. |
leptin is likely involved in behavioral regulation as leptin receptors are widely distributed in the brain, and leptin influences cortisol release, the mesoaccumbens dopamine pathway, serotonin synthesis, and hippocampal synaptic plasticity. |
2015-07-31 |
2023-08-13 |
human |
| Hao Li, Jamie L Scholl, Wenyu Tu, James E Hassell, Michael J Watt, Gina L Forster, Kenneth J Renne. Serotonergic responses to stress are enhanced in the central amygdala and inhibited in the ventral hippocampus during amphetamine withdrawal. The European journal of neuroscience. vol 40. issue 11. 2015-07-31. PMID:25234335. |
conversely, stress-induced increases in ventral hippocampal serotonin (5-ht) levels have been linked to coping mechanisms. |
2015-07-31 |
2023-08-13 |
rat |
| Hao Li, Jamie L Scholl, Wenyu Tu, James E Hassell, Michael J Watt, Gina L Forster, Kenneth J Renne. Serotonergic responses to stress are enhanced in the central amygdala and inhibited in the ventral hippocampus during amphetamine withdrawal. The European journal of neuroscience. vol 40. issue 11. 2015-07-31. PMID:25234335. |
when microdialysis was used to determine the effects of restraint on extracellular 5-ht, stress-induced increases in 5-ht levels were abolished in the ventral hippocampus and augmented in the central amygdala during amphetamine withdrawal. |
2015-07-31 |
2023-08-13 |
rat |
| Hao Li, Jamie L Scholl, Wenyu Tu, James E Hassell, Michael J Watt, Gina L Forster, Kenneth J Renne. Serotonergic responses to stress are enhanced in the central amygdala and inhibited in the ventral hippocampus during amphetamine withdrawal. The European journal of neuroscience. vol 40. issue 11. 2015-07-31. PMID:25234335. |
reverse dialysis of the glucocorticoid receptor antagonist mifepristone into the ventral hippocampus blocked the stress-induced increase in 5-ht levels in saline-pretreated rats, suggesting that glucocorticoid receptors mediate stress-induced increases in 5-ht levels in the ventral hippocampus. |
2015-07-31 |
2023-08-13 |
rat |
| Hao Li, Jamie L Scholl, Wenyu Tu, James E Hassell, Michael J Watt, Gina L Forster, Kenneth J Renne. Serotonergic responses to stress are enhanced in the central amygdala and inhibited in the ventral hippocampus during amphetamine withdrawal. The European journal of neuroscience. vol 40. issue 11. 2015-07-31. PMID:25234335. |
during amphetamine withdrawal, the absence of stress-induced increases in ventral hippocampal 5-ht levels combined with enhanced stress-induced serotonergic responses in the central amygdala may contribute to drug relapse by decreasing stress-coping ability and heightening stress responsiveness. |
2015-07-31 |
2023-08-13 |
rat |
| Feng-ze Jiang, Jing Lv, Dan Wang, Hai-ying Jiang, Ying-shun Li, Qing-hua Ji. [Effect of 5-HT1A receptors in the hippocampal DG on active avoidance learning in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 31. issue 1. 2015-07-26. PMID:26016238. |
to investigate the effects of serotonin (5-htia) receptors in the hippocampal dentate gyrus (dg) on active avoidance learning in rats. |
2015-07-26 |
2023-08-13 |
rat |
| Ana Carolina D Noseda, Lais S Rodrigues, Adriano D S Targa, Mariana F Aurich, Maria A B F Vital, Cláudio Da Cunha, Marcelo M S Lim. Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade. Behavioural brain research. vol 275. 2015-07-24. PMID:25218873. |
4-p-pdot treatment of the rotenone remsd group generated a decrement in 5-ht levels within the striatum, hippocampus and snpc. |
2015-07-24 |
2023-08-13 |
rat |
| Wei-Wei Ji, Rui-Peng Li, Meng Li, Shu-Yuan Wang, Xian Zhang, Xing-Xing Niu, Wei Li, Lu Yan, Yang Wang, Qiang Fu, Shi-Ping M. Antidepressant-like effect of essential oil of Perilla frutescens in a chronic, unpredictable, mild stress-induced depression model mice. Chinese journal of natural medicines. vol 12. issue 10. 2015-07-16. PMID:25443368. |
the contents of 5-hydroxytryptamine (5-ht) and its metabolite, 5-hydroxyindoleacetic acid (5-hiaa), in mouse hippocampus were determined by hplc-ecd. |
2015-07-16 |
2023-08-13 |
mouse |
| Wei-Wei Ji, Rui-Peng Li, Meng Li, Shu-Yuan Wang, Xian Zhang, Xing-Xing Niu, Wei Li, Lu Yan, Yang Wang, Qiang Fu, Shi-Ping M. Antidepressant-like effect of essential oil of Perilla frutescens in a chronic, unpredictable, mild stress-induced depression model mice. Chinese journal of natural medicines. vol 12. issue 10. 2015-07-16. PMID:25443368. |
the results showed that cums significantly decreased the levels of 5-ht and 5-hiaa in the hippocampus, with an increase in plasma il-6, il-1β, and tnf-α levels. |
2015-07-16 |
2023-08-13 |
mouse |
| E Hernández-Andrade, A J Cortés-Camberos, N F Díaz, H Flores-Herrera, G García-López, M González-Jiménez, A Santamaría, A Molina-Hernánde. Altered levels of brain neurotransmitter from new born rabbits with intrauterine restriction. Neuroscience letters. vol 584. 2015-06-23. PMID:25304540. |
the aim of this study was to evaluate the levels of gamma-aminobutyric acid, glutamate, dopamine and serotonin in three structures of the brain related to the above-mentioned function such as the cerebral cortex, the striatum, and the hippocampus in the chronic hypoxic newborn rabbit model. |
2015-06-23 |
2023-08-13 |
rabbit |
| Udo Dannlowski, Harald Kugel, Ronny Redlich, Adriane Halik, Ilona Schneider, Nils Opel, Dominik Grotegerd, Kathrin Schwarte, Christiane Schettler, Oliver Ambrée, Stephan Rust, Katharina Domschke, Volker Arolt, Walter Heindel, Bernhard T Baune, Thomas Suslow, Weiqi Zhang, Christa Hohof. Serotonin transporter gene methylation is associated with hippocampal gray matter volume. Human brain mapping. vol 35. issue 11. 2015-06-15. PMID:24862560. |
serotonin transporter gene methylation is associated with hippocampal gray matter volume. |
2015-06-15 |
2023-08-13 |
human |
| Udo Dannlowski, Harald Kugel, Ronny Redlich, Adriane Halik, Ilona Schneider, Nils Opel, Dominik Grotegerd, Kathrin Schwarte, Christiane Schettler, Oliver Ambrée, Stephan Rust, Katharina Domschke, Volker Arolt, Walter Heindel, Bernhard T Baune, Thomas Suslow, Weiqi Zhang, Christa Hohof. Serotonin transporter gene methylation is associated with hippocampal gray matter volume. Human brain mapping. vol 35. issue 11. 2015-06-15. PMID:24862560. |
the serotonin transporter (5-htt) and the 5-httlpr/rs25531 polymorphisms in its gene (slc6a4) have been associated with depression, increased stress-response, and brain structural alterations such as reduced hippocampal volumes. |
2015-06-15 |
2023-08-13 |
human |
| Jennifer Manning, Rebecca Kulbida, Prerana Rai, Lindsay Jensen, Judith Bouma, Sanjay P Singh, Dervla O'Malley, Deniz Yilmazer-Hank. Amitriptyline is efficacious in ameliorating muscle inflammation and depressive symptoms in the mdx mouse model of Duchenne muscular dystrophy. Experimental physiology. vol 99. issue 10. 2015-06-10. PMID:24972834. |
amitriptyline treatment had anxiolytic and antidepressant effects in mdx mice associated with elevations in serotonin levels in the amygdala and hippocampus. |
2015-06-10 |
2023-08-13 |
mouse |
| April Johnston, Chris J McBain, André Fisah. 5-Hydroxytryptamine1A receptor-activation hyperpolarizes pyramidal cells and suppresses hippocampal gamma oscillations via Kir3 channel activation. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:25107925. |
multiple 5-ht receptor subtypes are expressed in the ca3 region of the hippocampus and high doses of 5-ht reduce the power of induced gamma oscillations.hypothesizing that 5-ht may have cell- and receptor subtype-specific modulatory effects, we investigated the receptor subtypes, cell types and cellular mechanisms engaged by 5-ht in the modulation of gamma oscillations in mice and rats. |
2015-06-10 |
2023-08-13 |
mouse |
| April Johnston, Chris J McBain, André Fisah. 5-Hydroxytryptamine1A receptor-activation hyperpolarizes pyramidal cells and suppresses hippocampal gamma oscillations via Kir3 channel activation. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:25107925. |
we found that 5-ht decreases the power of kainate-induced hippocampal gamma oscillations in both species via the 5-ht1a receptor subtype. |
2015-06-10 |
2023-08-13 |
mouse |